Coffee and the Risk of Lymphoma: A Meta-analysis Article
Abstract
Background: Coffee is implicated in the susceptibility to several cancers. However, the association between coffee and lymphoma remains unclear. This meta-analysis aimed to assess quantitatively the association between coffee and the incidence of lymphoma.
Methods: A literature search was performed for cohort and case-control studies published using PubMed, Cochrane, and EMBASE databases. Studies were included if they reported relative ratios (RR) and corresponding 95% confidence intervals (CIs) of lymphoma with respect to coffee consumption. Pooled relative risk (RR) and its 95% confidence interval (CI) were calculated. All P values are two tailed
Results: Seven studies met the inclusion criteria, which included three cohort and four case-control studies. Compared with did not or seldom drink coffee per day, being no significantly association between coffee and risk of lymphoma (pooled RR: 1.05, 95%CI: 0.89-1.23). In the subgroup analysis, no significant association between coffee and lymphoma risk was detected not only in different study types (cohort studies RR: 1.29; 95% CI, 0.92-1.80; case control studies RR: 0.99; 95% CI, 0.82-1.99) but also in different regions (Europe RR: 1.21; 95% CI: 0.99-1.47; USA RR: 0.85; 95% CI, 0.62-1.15; Asia RR: 1.08, 95% CI: 0.84-1.40) and coffee consumption status (≥4cups/d 1.03, 95% CI: 0.69–1.56; ＜4cups/d RR: 1.06, 95% CI: 0.89- 1.26 ). The funnel plot revealed no evidence for publication bias.
Conclusion: There was no sufficient evidence to support coffee consumption association with the risk of lymphoma. Further well-designed large-scaled cohort studies are needed to provide conclusions that are more definitive.
Muller AM, Ihorst G, Mertelsmann R, Engelhardt M (2005). Epidemiology of non-Hodgkin's lymphoma (NHL): trends, geographic distribution, and etiology. Ann Hematol, 84(1):1-12.
Siegel R, Naishadham D, Jemal A (2012). Cancer statistics, 2012. CA Cancer J Clin, 62(1):10-29.
Hartge P, Devesa SS (1992). Quantification of the impact of known risk factors on time trends in non-Hodgkin's lymphoma incidence. Cancer Res, 52(19):5566s-9s.
Hosnijeh FS, Heederik D, Vermeulen R (2012). A review of the role of lymphoma markers and occupational and environmental exposures. Vet Q,32(2):61-73.
Yu X, Bao Z, Zou J, Dong J (2011). Coffee consumption and risk of cancers: a meta-analysis of cohort studies. BMC Cancer ,11:96.
Bohn SK, Blomhoff R, Paur I (2014). Coffee and cancer risk, epidemiological evidence, and molecular mechanisms. Mol Nutr Food Res, 58(5):915-30.
Stroup DF, Berlin JA, Morton SC,Olkin I,Williamson GD, Rennie D, Moher D, Becker BJ, Sipe TA, Thacker SB(2000). Meta-analysis of observa-tional studies in epidemiology: a pro-posal for reporting. Meta-analysis Of Observational Studies in Epidemiolo-gy (MOOSE) group. JAMA , 283(15):2008-12.
Stang A (2010). Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol,25(9):603-5.
Li MY, Zhu M, Zhu B, Wang ZQ (2013). Tryptase disturbs endocytic allergen degradation in intestinal epithelial cells. Anal Biochem,434(1):54-9.
Mantel N, Haenszel W (1959). Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst,22(4):719-48.
DerSimonian R, Laird N (1986). Meta-analysis in clinical trials.Control Clin Trials,7(3):177-88.
Egger M, Davey Smith G, Schneider M, Minder C (1997). Bias in meta-analysis detected by a simple, graphical test. BMJ ,315(7109):629-34.
Jacobsen BK, Bjelke E, Kvale G, Heuch I (1986). Coffee drinking, mortality, and cancer incidence: results from a Norwegian prospective study. J Natl Cancer Inst,76(5):823-31.
Stensvold I, Jacobsen BK (1994). Coffee and cancer: a prospective study of 43,000 Norwegian men and women. Cancer Causes Control,5(5):401-8.
Nilsson LM, Johansson I, Lenner P, Lindahl B, Van Guelpen B (2010). Consumption of filtered and boiled coffee and the risk of incident cancer: a prospective cohort study. Cancer Causes Control, 21(10):1533-44.
Tavani A, Negri E, Franceschi S, Talamini R, La Vecchia C (1994). Coffee consumption and risk of non-Hodgkin's lymphoma.Eur J Cancer Prev, 3(4):351-6.
Ward MH, Zahm SH, Weisenburger DD,Gridley G, Cantor K P, Saal RC, Blair A(1994). Dietary factors and non-Hodgkin's lymphoma in Nebraska (United States). Cancer Causes Con-trol,5(5):422-2.
Matsuo K, Hamajima N, Hirose K ,Inoue M, Takezaki T, Kuroishi T, Tajima K,(2001). Alcohol, smoking, and dietary status and susceptibility to malignant lymphoma in Japan: results of a hospital-based case-control study at Aichi Cancer Center. Jpn J Cancer Res,92(10):1011-7.
Chiu BC, Dave BJ, Ward MH ,Fought AJ,Hou L,Jain S,Gapstur S,Evens AM,Zahm SH,Blair A,Weisenburger DD,(2008). Dietary factors and risk of t(14;18)-defined subgroups of non-Hodgkin lymphoma. Cancer Causes Control,19(8):859-67.
Surh YJ (2003). Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer ,3(10):768-780.
Svilaas A, Sakhi AK, Andersen LF ,Svilaas T, Strom EC. Jacobs DR Jr, Ose L,Blomhoff R(2004). Intakes of antioxidants in coffee, wine, and vege-tables are correlated with plasma ca-rotenoids in humans. J Nutr,134(3):562-7.
Balstad TR, Carlsen H, Myhrstad MC,Kolberg M, Reiersen H, Gilen L, Ebihara K, Paur I, Blomhoff R, (2011). Coffee, broccoli and spices are strong inducers of electrophile re-sponse element-dependent transcrip-tion in vitro and in vivo - studies in electrophile response element trans-genic mice. Mol Nutr Food Res,55(2):185-97.
Bravi F, Bosetti C, Tavani A ,Bagnardi V, Gallus S, Negri E, Franceschi S, La Vecchia C(2007). Coffee drinking and hepatocellular carcinoma risk: a meta-analysis. Hepatology ,46(2):430-5.
Larsson SC, Wolk A (2007). Coffee consumption and risk of liver cancer: a meta-analysis. Gastroenterology ,132(5):1740-5.
Simonsson M, Soderlind V, Henningson M,Hjertberg M, Rose C, Ingvar C, Jernstrom H (2013). Coffee prevents early events in tamoxifen-treated breast cancer patients and modulates hormone receptor status. Cancer Causes Control, 24(5):929-40.
Tang N, Zhou B, Wang B, Yu R (2009). Coffee consumption and risk of breast cancer: a metaanalysis. Am J Obstet Gynecol,200(3):290-9.
Jiang W, Wu Y, Jiang X (2013). Coffee and caffeine intake and breast cancer risk: an updated dose-response meta-analysis of 37 published studies. Gynecol Oncol,129(3):620-9.
Tian C, Wang W, Hong Z, Zhang X (2013). Coffee consumption and risk of colorectal cancer: a dose-response analysis of observational studies. Cancer Causes Control, 24(6):1265-8.
Galeone C, Turati F, La Vecchia C, Tavani A (2010). Coffee consumption and risk of colorectal cancer: a meta-analysis of case-control studies. Cancer Causes Control ,21(11):1949-59.
Bosire C, Stampfer MJ, Subar AF, Wilson KM, Park Y, Sinha R (2013). Coffee consumption and the risk of overall and fatal prostate cancer in the NIH-AARP Diet and Health Study. Cancer Causes Control, 24(8):1527-34.
Li Q, Kakizaki M, Sugawara Y ,Tomata Y, Watanabe T, Nishino Y, Tsuji I(2013). Coffee consumption and the risk of prostate cancer: the Ohsaki Cohort Study. Br J Cancer ,108(11):2381-9.
Arab L, Su LJ, Steck SE,Ang A, Fon-tham ET, Bensen JT, Mohler J L. (2012). Coffee consumption and pros-tate cancer aggressiveness among Af-rican and Caucasian Americans in a population-based study. Nutr Can-cer,64(5):637-42.
Steevens J, Schouten LJ, Verhage BA, Goldbohm RA, van den Brandt PA (2007). Tea and coffee drinking and ovarian cancer risk: results from the Netherlands Cohort Study and a meta-analysis. Br J Cancer ,97(9):1291-4.
Bhoo-Pathy N, Uiterwaal CS, Dik VK (2013). Intake of coffee, decaffeinated coffee, or tea does not affect risk for pancreatic cancer: results from the European Prospective Investigation into Nutrition and Cancer Study. Clin Gastroenterol Hepatol,11(11): 1486-92.
Bidel S, Hu G, Jousilahti P, Pukkala E, Hakulinen T, Tuomilehto J (2013).Coffee consumption and risk of gastric and pancreatic cancer--a prospective cohort study. International journal of cancer. Int J Cancer ,132(7):1651-9.
Jiang X, Zhang D, Jiang W (2014).Coffee and caffeine intake and incidence of type 2 diabetes mellitus: a meta-analysis of prospective studies. Eur J Nutr,53(1): 25-38.
Mitri J, Castillo J, Pittas AG (2008). Diabetes and risk of Non-Hodgkin's lymphoma: a meta-analysis of observational studies. Diabetes Care ,31(12): 2391-7.
Ferruzzi MG (2010). The influence of beverage composition on delivery of phenolic compounds from coffee and tea. Physiol Behav,100(1): 33-41.
Abraham SK, Vukicevic V and Stopper H (2004). Coffee-mediated protective effects against directly acting genotoxins and gamma-radiation in mouse lymphoma cells. Cell Biol Toxicol ,20(2): 121-32.
Abraham SK, Stopper H (2004). Anti-genotoxicity of coffee against N-methyl-N-nitro-N-nitrosoguanidine in mouse lymphoma cells. Mutat Res,561(1-2): 23-33.
Loftfield E, Shiels MS, Graubard BI ,Katki HA, Chaturvedi A K, Trabert B, Pinto L A, Kemp TJ, Shebl FM, Mayne ST, Wentzensen N, Purdue MP, Hildesheim A, Sinha R, Freed-man ND(2015). Associations of Cof-fee Drinking with Systemic Immune and Inflammatory Markers.Cancer Epi-demiol Biomarkers Prev,24(7): 1052-60.
Raffetti E, Donato F, Castelnuovo F ,Paraninfo G, Di Filippo E, Segala D, Cologni G, Bandera A, Zacchi F, Digiambenedetto S, Di Pietro M, Cas-telli F, Quiros-Roldan E(2015). The prognostic role of systemic inflamma-tory markers on HIV-infected patients with non-Hodgkin lymphoma, a mul-ticenter cohort study.J Transl Med,13: 89.
Ullrich K, Blumenthal-Barby F, Lamprecht B,Kochert K, Lenze D, Hummel M, Mathas S, Dorken B, Janz M(2015). The IL-15 cytokine system provides growth and survival signals in Hodgkin lymphoma and enhances the inflammatory phenotype of HRS cells. Leukemia ,29(5): 1213-8.
Tsioufis C, Dimitriadis K, Vasiliadou C ,Taxiarchou E, Vezali E, Tsiamis E, Stefanadis C, Kallikazaros I(2006). Heavy coffee consumption in con-junction with smoking is accompanied by increased inflammatory processes and impaired thrombosis/fibrinolysis system in essential hypertensive sub-jects. J Hum Hypertens,20(6): 470-2.
Wilson KM, Mucci LA, Rosner BA , Wil-lett WC (2010).A prospective study on dietary acrylamide intake and the risk for breast, endometrial, and ovari-an cancers. Cancer Epidemiol Biomarkers Prev ,19(10): 2503-15.
Hogervorst JG, Baars BJ, Schouten LJ, Konings EJ, Goldbohm RA,van den Brandt PA (2010). The carcinogenicity of dietary acrylamide intake: a comparative discussion of epidemiological and experimental animal research. Crit Rev Toxicol,40(6): 485-512.
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| Issue | Vol 45 No 9 (2016) | |
| Section | Review Article(s) | |
| Keywords | ||
| Lymphoma Coffee Cohort study Case-control study Meta-analysis | ||
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