Effects of Multi-Sensory Stimulation on Apathy Symptoms in Elderly Patients with Alzheimer's Disease
-
Yang Li
,
Yu Wang
,
Teng Zhao
,
Xuewen Yang
,
Yinghui Lv
,
Shumei Li
,
Xiujun Yang
,
Li Li
Abstract
Background: We aimed to explore the effect of multi-sensory stimulation on apathy symptoms in elderly patients with Alzheimer's disease (AD).
Methods: Eighty elderly patients with AD admitted to the Third Affiliated Hospital of Qiqihar Medical University, China from January 2022 to February 2023 were selected as the research objects by convenient sampling method. According to the random number table, they were divided into intervention group and control group, with 40 cases in each group. The control group was given routine nursing, while the intervention group was given multi-sensory stimulation based on this nursing. Apathy evaluation scale (AES), Behavioral pathology in Alzheimer’s disease rating scale (BEHAVE-AD) and Quality of Life Scale for dementia patients（QoL-AD） were used to compare the results.
Results: Compared with the control group, the scores of AES and BEHAVE-AD in intervention group were lower (t was -7.312 and 11.88 respectively, P < 0.05), and the scores of QoL-AD in intervention group were significantly higher than those in control group were (t was -15.311, P < 0.01).
Conclusion: Multi-sensory stimulation can relieve apathy symptoms, mental and behavioral symptoms and improve the quality of life of elderly patients with AD, which is worth popularizing in clinical practice.
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2. Gómez GM, Gómez GJ (2017). Music ther-apy and AD: Cognitive, psychological, and behavioural effects. Neurologia, 32(5): 300-308.
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5. Zhu CW, Grossman HT, Sano M (2019). Why Do They Just Sit? Apathy symp-toms as a Core Symptom of Alzheimer Disease. Am J Geriatr Psychiatry, 27(4): 395-405.
6. Strom BS, Ytrehus S, Grov EK (2016). Sen-sory stimulation for persons with de-mentia: a review of the literature. J Clin Nurs, 25(13-14): 1805-1834.
7. Smith BC, D'Amico M (2020). Sensory-Based Interventions for Adults with Dementia and AD: A Scoping Review. Occup Ther Health Care, 34(3): 171-201.
8. UK NCCF (2007). Dementia: A NICE-SCIE Guideline on Supporting People With Dementia and Their Carers in Health and Social Care. Leicester (UK): British Psychological Society.
9. Prins AJ, Scherder E, van Straten A, et al (2020). Sensory Stimulation for Nursing-Home Residents: Systematic Review and Meta-Analysis of Its Effects on Sleep Quality and Rest-Activity Rhythm in Dementia. Dement Geriatr Cogn Disord, 49(3): 219-234.
10. Marin RS, Biedrzycki RC, Firinciogullari S (1991). Reliability and validity of the Apathy symptoms Evaluation Scale. Psy-chiatry Res, 38(2): 143-162.
11. Reisberg B, Auer SR, Monteiro IM (1996). Behavioral pathology in AD (BEHAVE-AD) rating scale. Int Psychogeriatr, 8 Suppl 3: 301-308, 351-354.
12. Sung-Wan K, ShinIlSeon (2006). Patients’ versus caregivers’ reports of quality of life in AD. Journal of the Korean Society of Biological Therapies in Psychiatry, 12(2): 224-230.
13. Lanctot KL, Aguera-Ortiz L, Brodaty H, et al (2017). Apathy symptoms associated with neurocognitive disorders: Recent progress and future directions. Alzheimers Dement, 13(1): 84-100.
14. van der Linde RM, Matthews FE, Dening T, et al (2017). Patterns and persistence of behavioural and psychological symp-toms in those with cognitive impair-ment: the importance of apathy symp-toms. Int J Geriatr Psychiatry, 32(3): 306-315.
15. Dauphinot V, Delphin-Combe F, Mou-choux C, et al (2015). Risk factors of caregiver burden among patients with AD or related disorders: a cross-sectional study. J Alzheimers Dis, 44(3): 907-916.
16. Picillo M, Santangelo G, Moccia M, et al (2016). Serum uric acid is associated with apathy symptoms in early, drug-naive Parkinson's disease. J Neural Transm (Vi-enna), 123(4): 371-377.
17. Nijsten J, Leontjevas R, Pat-El R, et al (2017). Apathy symptoms: Risk Factor for Mortality in Nursing Home Patients. J Am Geriatr Soc, 65(10): 2182-2189.
18. Orgeta V, Tabet N, Nilforooshan R, et al (2017). Efficacy of Antidepressants for Depression in AD: Systematic Review and Meta-Analysis. J Alzheimers Dis, 58(3): 725-733.
19. Zhao QF, Tan L, Wang HF, et al (2016). The prevalence of neuropsychiatric symptoms in AD: Systematic review and meta-analysis. J Affect Disord, 190: 264-271.
20. Gilmore-Bykovskyi A, Block L, Johnson R, et al (2019). Symptoms of apathy symp-toms and passivity in dementia: A simul-taneous concept analysis. J Clin Nurs, 28(3-4): 410-419.
21. Baker R, Holloway J, Holtkamp CC, et al (2003). Effects of multi-sensory stimula-tion for people with dementia. J Adv Nurs, 43(5): 465-477.
22. Staal JA, Sacks A, Matheis R, et al (2007). The effects of Snoezelen (multi-sensory behavior therapy) and psychiatric care on agitation, apathy symptoms, and ac-tivities of daily living in dementia pa-tients on a short term geriatric psychiat-ric inpatient unit. Int J Psychiatry Med, 37(4): 357-370.
23. Starkstein SE, Jorge R, Mizrahi R, et al (2006). A prospective longitudinal study of apathy symptoms in AD. J Neurol Neurosurg Psychiatry, 77(1): 8-11.
24. Padala PR, Boozer EM, Lensing SY, et al (2020). Neuromodulation for Apathy symptoms in AD: A Double-Blind, Ran-domized, Sham-Controlled Pilot Study. J Alzheimers Dis, 77(4): 1483-1493.
25. Cruz J, Marques A, Barbosa AL, et al (2011). Effects of a motor and multisensory-based approach on residents with mod-erate-to-severe dementia. Am J Alzheimers Dis Other Demen, 26(4): 282-289.
26. Maseda A, Sanchez A, Marante MP, et al (2014). Multi-sensory stimulation on mood, behavior, and biomedical pa-rameters in people with dementia: is it more effective than conventional one-to-one stimulation? Am J Alzheimers Dis Other Demen, 29(7): 637-647.
27. McDermott O, Crellin N, Ridder HM, et al (2013). Music therapy in dementia: a nar-rative synthesis systematic review. Int J Geriatr Psychiatry, 28(8): 781-794.
28. van Weert JC, van Dulmen AM, Spreeu-wenberg PM, et al (2005). Behavioral and mood effects of snoezelen integrated into 24-hour dementia care. J Am Geriatr Soc, 53(1): 24-33.
29. Ward-Smith P, Llanque SM, Curran D (2009). The effect of multi-sensory stim-ulation on persons residing in an ex-tended care facility. Am J Alzheimers Dis Other Demen, 24(6): 450-455.
30. Martorell AJ, Paulson AL, Suk HJ, et al (2019). Multi-sensory Gamma Stimula-tion Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. Cell, 177(2): 256-271.
31. Todder D, Levartovsky M, Dwolatzky T (2016). Measuring the effect of multi-sensory stimulation in the snoezelen room on sleep quality of Alzheimer pa-tients using actigraph. Harefuah, 155(12): 727-730.
2. Gómez GM, Gómez GJ (2017). Music ther-apy and AD: Cognitive, psychological, and behavioural effects. Neurologia, 32(5): 300-308.
3. Ismail Z, Smith EE, Geda Y, et al (2016). Neuropsychiatric symptoms as early manifestations of emergent dementia: Provisional diagnostic criteria for mild behavioral impairment. Alzheimers De-ment, 12(2): 195-202.
4. Zhao QF, Tan L, Wang HF, et al (2016). Corrigendum to: "The prevalence of neuropsychiatric symptoms in AD: Sys-tematic review and meta-analysis". J Af-fect Disord, 206: 8.
5. Zhu CW, Grossman HT, Sano M (2019). Why Do They Just Sit? Apathy symp-toms as a Core Symptom of Alzheimer Disease. Am J Geriatr Psychiatry, 27(4): 395-405.
6. Strom BS, Ytrehus S, Grov EK (2016). Sen-sory stimulation for persons with de-mentia: a review of the literature. J Clin Nurs, 25(13-14): 1805-1834.
7. Smith BC, D'Amico M (2020). Sensory-Based Interventions for Adults with Dementia and AD: A Scoping Review. Occup Ther Health Care, 34(3): 171-201.
8. UK NCCF (2007). Dementia: A NICE-SCIE Guideline on Supporting People With Dementia and Their Carers in Health and Social Care. Leicester (UK): British Psychological Society.
9. Prins AJ, Scherder E, van Straten A, et al (2020). Sensory Stimulation for Nursing-Home Residents: Systematic Review and Meta-Analysis of Its Effects on Sleep Quality and Rest-Activity Rhythm in Dementia. Dement Geriatr Cogn Disord, 49(3): 219-234.
10. Marin RS, Biedrzycki RC, Firinciogullari S (1991). Reliability and validity of the Apathy symptoms Evaluation Scale. Psy-chiatry Res, 38(2): 143-162.
11. Reisberg B, Auer SR, Monteiro IM (1996). Behavioral pathology in AD (BEHAVE-AD) rating scale. Int Psychogeriatr, 8 Suppl 3: 301-308, 351-354.
12. Sung-Wan K, ShinIlSeon (2006). Patients’ versus caregivers’ reports of quality of life in AD. Journal of the Korean Society of Biological Therapies in Psychiatry, 12(2): 224-230.
13. Lanctot KL, Aguera-Ortiz L, Brodaty H, et al (2017). Apathy symptoms associated with neurocognitive disorders: Recent progress and future directions. Alzheimers Dement, 13(1): 84-100.
14. van der Linde RM, Matthews FE, Dening T, et al (2017). Patterns and persistence of behavioural and psychological symp-toms in those with cognitive impair-ment: the importance of apathy symp-toms. Int J Geriatr Psychiatry, 32(3): 306-315.
15. Dauphinot V, Delphin-Combe F, Mou-choux C, et al (2015). Risk factors of caregiver burden among patients with AD or related disorders: a cross-sectional study. J Alzheimers Dis, 44(3): 907-916.
16. Picillo M, Santangelo G, Moccia M, et al (2016). Serum uric acid is associated with apathy symptoms in early, drug-naive Parkinson's disease. J Neural Transm (Vi-enna), 123(4): 371-377.
17. Nijsten J, Leontjevas R, Pat-El R, et al (2017). Apathy symptoms: Risk Factor for Mortality in Nursing Home Patients. J Am Geriatr Soc, 65(10): 2182-2189.
18. Orgeta V, Tabet N, Nilforooshan R, et al (2017). Efficacy of Antidepressants for Depression in AD: Systematic Review and Meta-Analysis. J Alzheimers Dis, 58(3): 725-733.
19. Zhao QF, Tan L, Wang HF, et al (2016). The prevalence of neuropsychiatric symptoms in AD: Systematic review and meta-analysis. J Affect Disord, 190: 264-271.
20. Gilmore-Bykovskyi A, Block L, Johnson R, et al (2019). Symptoms of apathy symp-toms and passivity in dementia: A simul-taneous concept analysis. J Clin Nurs, 28(3-4): 410-419.
21. Baker R, Holloway J, Holtkamp CC, et al (2003). Effects of multi-sensory stimula-tion for people with dementia. J Adv Nurs, 43(5): 465-477.
22. Staal JA, Sacks A, Matheis R, et al (2007). The effects of Snoezelen (multi-sensory behavior therapy) and psychiatric care on agitation, apathy symptoms, and ac-tivities of daily living in dementia pa-tients on a short term geriatric psychiat-ric inpatient unit. Int J Psychiatry Med, 37(4): 357-370.
23. Starkstein SE, Jorge R, Mizrahi R, et al (2006). A prospective longitudinal study of apathy symptoms in AD. J Neurol Neurosurg Psychiatry, 77(1): 8-11.
24. Padala PR, Boozer EM, Lensing SY, et al (2020). Neuromodulation for Apathy symptoms in AD: A Double-Blind, Ran-domized, Sham-Controlled Pilot Study. J Alzheimers Dis, 77(4): 1483-1493.
25. Cruz J, Marques A, Barbosa AL, et al (2011). Effects of a motor and multisensory-based approach on residents with mod-erate-to-severe dementia. Am J Alzheimers Dis Other Demen, 26(4): 282-289.
26. Maseda A, Sanchez A, Marante MP, et al (2014). Multi-sensory stimulation on mood, behavior, and biomedical pa-rameters in people with dementia: is it more effective than conventional one-to-one stimulation? Am J Alzheimers Dis Other Demen, 29(7): 637-647.
27. McDermott O, Crellin N, Ridder HM, et al (2013). Music therapy in dementia: a nar-rative synthesis systematic review. Int J Geriatr Psychiatry, 28(8): 781-794.
28. van Weert JC, van Dulmen AM, Spreeu-wenberg PM, et al (2005). Behavioral and mood effects of snoezelen integrated into 24-hour dementia care. J Am Geriatr Soc, 53(1): 24-33.
29. Ward-Smith P, Llanque SM, Curran D (2009). The effect of multi-sensory stim-ulation on persons residing in an ex-tended care facility. Am J Alzheimers Dis Other Demen, 24(6): 450-455.
30. Martorell AJ, Paulson AL, Suk HJ, et al (2019). Multi-sensory Gamma Stimula-tion Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. Cell, 177(2): 256-271.
31. Todder D, Levartovsky M, Dwolatzky T (2016). Measuring the effect of multi-sensory stimulation in the snoezelen room on sleep quality of Alzheimer pa-tients using actigraph. Harefuah, 155(12): 727-730.
| Files | ||
| Issue | Vol 53 No 6 (2024) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/ijph.v53i6.15908 | |
| Keywords | ||
| Multi-sensory stimulation Elderly Alzheimer's disease Apathy Mental behavior Quality of life | ||
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How to Cite
1.
Li Y, Wang Y, Zhao T, Yang X, Lv Y, Li S, Yang X, Li L. Effects of Multi-Sensory Stimulation on Apathy Symptoms in Elderly Patients with Alzheimer’s Disease. Iran J Public Health. 2024;53(6):1343-1351.
