HATCH Score for Predicting Mortality in COVID-19 Patients
Abstract
Background: We aimed to evaluate the relationship between HATCH score [hypertension, age >75 yr, previous transient ischemic attack (TIA) or stroke (doubled), chronic obstructive pulmonary disease, heart failure (doubled)] and in-hospital mortality in COVID-19 patients.
Methods: Overall, 572 COVID-19 patients hospitalized between Mar 15 and Apr 15, 2020, were included in this multicenter retrospective study, in Turkey. The HATCH score of each patient was calculated. Mortality results were followed for 50 days. The patients were divided into 2 groups developing mortality (n=267) and non-mortality (n=305). Clinical outcomes were defined as in-hospital mortality improvement status.
Results: HATCH scores in non-survivors of COVID-19 were significantly higher than in survivors (P<0.001). In logistic regression analysis, HATCH score (OR: 1.253, 95% CI: 1.003–1.565; P=0.047), platelet count (OR: 0.995, 95% CI: 0.993-0.998; P<0.001), C-reactive protein level (OR: 1.010, 95% CI: 1.007-1.013, P<0.001) and estimated glomerular filtration ratio (eGFR) level (OR: 0.963, 95% CI: 0.953-0.973; P<0.001) were independent predictors of in-hospital mortality in COVID-19 patients.
Conclusion: The HATCH score is useful in predicting in-hospital mortality in patients hospitalized with COVID-19.
2. De Vos CB, Pisters R, Nieuwlaat R, et al. (2010). Progression from paroxysmal to persistent atrial fibrillation: clinical correlates and prognosis. J Am Coll Cardiol, 55 (8): 725-31.
3. Wynants L, Van Calster B, Collins GS, et al (2020). Prediction models for diagnosis and prognosis in Covid-19: systematic review and critical appraisal. British BMJ, 369: m1328.
4. Bilimsel Denetleme Kurulu Çalışması (2022). Covid-19 (Sars-CoV-2 Enfeksiyonu) Erişkin Hasta Tedavisi [Available from: https://covid19.saglik.gov.tr/Eklenti/43095/0/covid-19rehberieriskinhastayonetimivetedavi-12042022pdf.pdf
5. Pedersen SF, Ho Y-C (2020). SARS-CoV-2: a storm is raging. J Clin Invest, 130 (5): 2202-05.
6. Fang X, Li S, Yu H, et al (2020). Epidemiological, comorbidity factors with severity and prognosis of COVID-19: a systematic review and meta-analysis. Aging (Albany NY), 12 (13): 12493-12503.
7. Ejaz H, Alsrhani A, Zafar A, et al. (2020). COVID-19 and comorbidities: Deleterious impact on infected patients. Journal of infection and public health, 13 (12): 1833-39.
8. Quisi A, Alıcı G, Harbalıoğlu H, et al (2020). The CHA2DS2-VASc score and in-hospital mortality in patients with COVID-19: a multicenter retrospective cohort study. Turk Kardiyol Dern Ars, 48 (7): 656-63.
9. Abacioglu OO, Yildirim A (2021). The ATRIA score is superior to the m-CHA 2 DS 2-Vasc score in predicting in-hospital mortality in COVID-19. Rev Assoc Med Bras, 67: 443-48.
10. Aciksari G, Cetinkal G, Kocak M, et al. (2021). Evaluation of Modified ATRIA Risk Score in Predicting Mortality in Hospitalized Patients With COVID-19. Am J Med Sci, 362 (6): 553-61.
11. Gunduz R, Yildiz BS, Ozdemir IH, et al. (2021). CHA2DS2-VASc score and modified CHA2DS2-VASc score can predict mortality and intensive care unit hospitalization in COVID-19 patients. J Thromb Thrombolysis, 52 (3): 914-24.
12. Pranata R, Huang I, Lim MA, et al (2020). Impact of cerebrovascular and cardiovascular diseases on mortality and severity of COVID-19–systematic review, meta-analysis, and meta-regression. J Stroke Cerebrovasc Dis, 29 (8): 104949.
13. Yu J-N, Wu B-B, Yang J, et al (2021). Cardio-cerebrovascular disease is associated with severity and mortality of COVID-19: a systematic review and meta-analysis. Biol Res Nurs, 23 (2): 258-69.
14. Gao C, Cai Y, Zhang K, et al (2020). Association of hypertension and antihypertensive treatment with COVID-19 mortality: a retrospective observational study. Eur Heart J, 41 (22): 2058-66.
15. Leung JM, Niikura M, Yang CWT, et al. (2020). Covid-19 and COPD. Eur Respir J, 56 (2): 2002108.
16. Ho FK, Petermann-Rocha F, Gray SR, et al (2020). Is older age associated with COVID-19 mortality in the absence of other risk factors? General population cohort study of 470,034 participants. PLoS One, 15 (11): e0241824.
17. Smilowitz NR, Kunichoff D, Garshick M, et al (2021). C-reactive protein and clinical outcomes in patients with COVID-19. Eur Heart J, 42 (23): 2270-79.
18. Longhitano E, Nardi C, Calabrese V, et al (2021). Hypernatraemia and low eGFR at hospitalization in COVID-19 patients: a deadly combination. Clinical Kidney Journal, 14 (10): 2227-33.
19. Bi X, Su Z, Yan H, et al (2020). Prediction of severe illness due to COVID-19 based on an analysis of initial Fibrinogen to Albumin Ratio and Platelet count. Platelets, 31 (5): 674-79.
Files | ||
Issue | Vol 51 No 12 (2022) | |
Section | Original Article(s) | |
DOI | https://doi.org/10.18502/ijph.v51i12.11462 | |
Keywords | ||
SARS-CoV-2 Score Mortality |
Rights and permissions | |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |