Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 12 2022 12 17 2717 2723 Gökhan Alıcı Department of Cardiology, Adana City Training and Research Hospital, University of Health Sciences, Adana, Turkey Ömer Genç Department of Cardiology, Cam and Sakura City Hospital, University of Health Sciences, Istanbul, Turkey Hazar Harbalıoğlu Department of Cardiology, Duzce Atatürk State Hospital, Duzce, Turkey Ahmed Başhir Department of Internal Medicine, Somalia-Turkey Training and Research Hospital, Mogadishu, Somalia Samir Allahverdiyev Department of Cardiology, Istanbul Aydın University VM Medical Park Florya Hospital, Istanbul, Turkey Abdullah Yıldırım Department of Cardiology, Adana City Training and Research Hospital, University of Health Sciences, Adana, Turkey Alaa Quisi Department of Cardiology, Medline Hospital Adana, Adana, Turkey Örsan Urgun Department of Cardiology, Kozan State Hospital, Adana, Turkey İbrahim Kurt Department of Cardiology, Adana City Training and Research Hospital, University of Health Sciences, Adana, Turkey 2022 02 19 2022 12 17 Background: We aimed to evaluate the relationship between HATCH score [hypertension, age >75 yr, previous transient ischemic attack (TIA) or stroke (doubled), chronic obstructive pulmonary disease, heart failure (doubled)] and in-hospital mortality in COVID-19 patients. Methods: Overall, 572 COVID-19 patients hospitalized between Mar 15 and Apr 15, 2020, were included in this multicenter retrospective study, in Turkey. The HATCH score of each patient was calculated. Mortality results were followed for 50 days. The patients were divided into 2 groups developing mortality (n=267) and non-mortality (n=305). Clinical outcomes were defined as in-hospital mortality improvement status. Results: HATCH scores in non-survivors of COVID-19 were significantly higher than in survivors (P<0.001). In logistic regression analysis, HATCH score (OR: 1.253, 95% CI: 1.003–1.565; P=0.047), platelet count (OR: 0.995, 95% CI: 0.993-0.998; P<0.001), C-reactive protein level (OR: 1.010, 95% CI: 1.007-1.013, P<0.001) and estimated glomerular filtration ratio (eGFR) level (OR: 0.963, 95% CI: 0.953-0.973; P<0.001) were independent predictors of in-hospital mortality in COVID-19 patients. Conclusion: The HATCH score is useful in predicting in-hospital mortality in patients hospitalized with COVID-19.   https://ijph.tums.ac.ir/index.php/ijph/article/view/27915 https://ijph.tums.ac.ir/index.php/ijph/article/download/27915/7802