Association between Indoor Environment, Blood Trace Elements, and Immune Globulin among Workers from Vegetables Plastic Greenhouses in Yinchuan, China
-
Honghui Li
,
Jiangping Li
,
Wei Sun
,
Lijun Dong
,
Lingqin Zhu
,
Zhen Jiang
,
Huifang Yang
Abstract
Background: To study the association between indoor environment (MiE), blood trace elements (BTE), and immune globulin (PRO) among workers from vegetables plastic greenhouse, and to assess the mediate effects on MiE and PRO by BTE.
Methods: Overall, 168 practitioner and corresponding sheds were included from cross-sectional study in 2016. BTE and PRO were determined by physical test and MiE data from field and laboratory measurement. The association was assessed using canonical correlation analysis. The direct and indirect effects between MiE, PRO and BTE were conducted by structural equation model. 5000 times bootstrap methods were performed to estimate coefficient and 95% confidence interval.
Results: MiE was moderately correlated with BTE (canonical coefficient = 0.439), and BTE was strongly correlated with PRO (canonical coefficient = 0.514 and 0.481). No statistical evidence was found for the overall impact of MiE on PRO, and BTE as an intermediary affecting its relevance was not confirmed. Only the path way of the BTE impact on PRO had a significant positive effect (P=0.012).
Conclusion: BTE was positively associated with PRO, therefore, reducing exposure in greenhouse is a pathway to remain blood trace elements, and further effect the immune protein in human body.
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37. Guo Y, Barnett AG, Pan X, et al (2011). The impact of temperature on mortality in Tianjin, China: a case-crossover design with a distributed lag nonlinear model. Environ Health Perspect, 119(12): 1719-1725.
38. Hänninen O, Knol AB, Jantunen M, et al (2014). Environmental burden of disease in Europe: assessing nine risk factors in six countries. Environ Health Perspect, 122(5): 439-446.
2. Yu J, Zhou J (2016). Progress in Protected Vegetable Production and Research dur-ing China's 12th Five-Year Plan. Vegetable of China, 9: 18-30.
3. Li X, Jiao W, Xiao R, et al (2015). Soil pollu-tion and site remediation policies in Chi-na: A review. Environ Rev, 23: 263-274.
4. Allardyce CS, Fankhauser C, Zakeeruddin SM, et al (2017). The influence of green-house-integrated photovoltaics on crop production. Solar Energy, 155: 517-522.
5. Basu R, Samet JM (2002). Relation between elevated ambient temperature and mortal-ity: a review of the epidemiologic evi-dence. Epidemiol Rev, 24(2): 190-202.
6. Kovats RS, Hajat S (2008). Heat stress and public health: a critical review. Annu Rev Public Health, 29: 41-55.
7. Medina-Ramón M, Zanobetti A, Cavanagh D P, Schwartz J (2006). Extreme tem-peratures and mortality: assessing effect modification by personal characteristics and specific cause of death in a multi-city case-only analysis. Environ Health Perspect, 114(9): 1331-1336.
8. Basu R, Ostro BD (2008). A multicounty analysis identifying the populations vul-nerable to mortality associated with high ambient temperature in California. Am J Epidemiol, 168(6): 632-637.
9. He F, Jiang R, Chen Q, et al (2009). Nitrous oxide emissions from an intensively managed greenhouse vegetable cropping system in Northern China. Environ Pollut, 157(5): 1666-1672.
10. Hui-ping S (2013). Occupational hazards and its defense measures in operating environment of greenhouse planting. J Occupation and Health, Corpus ID: 130102723.
11. Kampa M, Castanas E (2008). Human health effects of air pollution. Environ Pol-lut, 151(2): 362-367.
12. Moreno JA, Nicholls E, Ojeda N, et al (2015). Caregiving in Dementia and its Impact on Psychological Functioning and Health-Related Quality of Life: Findings from a Colombian Sample. J Cross Cult Gerontol, 30(4): 393-408.
13. Hayes AF (2009). Beyond Baron and Kenny: Statistical Mediation Analysis in the New Millennium. Communication Monographs, 76: 408-420.
14. Maggini S, Wintergerst ES, Beveridge S, Hornig DH (2007). Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. Br J Nutr, 98 Suppl 1: S29-35.
15. Wintergerst ES, Maggini S, Hornig DH (2007). Contribution of selected vitamins and trace elements to immune function. Ann Nutr Metab, 51(4): 301-323.
16. Girodon F, Galan P, Monget AL, et al (1999). Impact of trace elements and vit-amin supplementation on immunity and infections in institutionalized elderly pa-tients: a randomized controlled trial. MIN. VIT. AOX. Geriatric network. Arch Intern Med, 159(7): 748-754.
17. Basu N, Todgham AE, Ackerman PA, et al (2002). Heat shock protein genes and their functional significance in fish. Gene, 295(2): 173-183.
18. Cohen J (1969). Statistical Power Analysis for the Behavioral Sciences. Academic Press, New York, xvi + 416 pp.
19. Asahi R, Morikawa T, Ohwaki T, et al (2001). Visible-light photocatalysis in ni-trogen-doped titanium oxides. Science, 293(5528): 269-271.
20. DeLuca TH, Gundale MJ, MacKenzie MD, et al (2015). Biochar effects on soil nutri-ent transformations. In: Biochar for environ-mental management. 2: 421-454. eBook ISBN 9781849770552.
21. He X, Pang S, Ma JB, Zhang YH (2017). In-fluence of relative humidity on heteroge-neous reactions of O 3 and O 3 /SO 2 with soot particles: Potential for envi-ronmental and health effects. Atmospheric Environment, 165: 198-206.
22. Ibs KH, Rink L (2003). Zinc-Altered Im-mune Function. J Nutr, 133(1): 1452S- 6S.
23. Rink L, Kirchner H (2000). Zinc-altered immune function and cytokine produc-tion. J Nutr, 130(5S Suppl): 1407s-1411s.
24. Chandra R K,Dayton D H (1982). Trace El-ement Regulation of Immunity and Infec-tion. Nutr Res, 2, 721-733.
25. Land S, Park-Holohan SJ, Smith NP, et al (2017). A model of cardiac contraction based on novel measurements of tension development in human cardiomyocytes. J Mol Cell Cardiol, 106: 68-83.
26. Larsson TE, Olauson H (2015). FGF23 and Phosphate: Two Cardiovascular Toxins with Distinct Toxicity Profiles? Cardio-Renal Clinical Challenges. Springer, Cham, 73-80.
27. Kurian GA, Paddikkala J (2007). Effect of Intra-Operative Magnesium Supplemen-tation on Plasma Antioxidant Levels, Trace Elements and Electrolyte Balance in Serum of Coronary Artery Bypass Graft Patients. J Clin Basic Cardiol, 10: 11-15.
28. Kusuoka H, Weisfeldt ML, Zweier JL, et al (1986). Mechanism of early contractile failure during hypoxia in intact ferret heart: evidence for modulation of maxi-mal Ca2+-activated force by inorganic phosphate. Circ Res, 59(3): 270-282.
29. Palmer S, Kentish JC (1994). The role of troponin C in modulating the Ca2+ sen-sitivity of mammalian skinned cardiac and skeletal muscle fibres. J Physiol, 480(Pt 1): 45-60.
30. Bayır A, Kara H, Kıyıcı A, et al (2013). Levels of selenium, zinc, copper, and cardiac troponin I in serum of patients with acute coronary syndrome. Biol Trace Elem Res, 154(3): 352-356.
31. Shankar AH, Prasad AS (1998). Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr, 68(2 Suppl): 447s-463s.
32. Prasad AS (2008). Zinc in human health: ef-fect of zinc on immune cells. Mol Med, 14(5-6): 353-357.
33. Huang J, Hu RF, Cao J, Rozelle S (2008). Training programs and in-the-field guid-ance to reduce China's overuse of fertiliz-er without hurting profitability. Journal of Soil Water Conservation, 63: 165A-167A.
34. Miller DM, Gulbis JM (2014). The molecules of life: physical and chemical principles. Crystallography Reviews, 20: 307-311.
35. Michaelsen KF, Greer FR (2014). Protein needs early in life and long-term health. Am J Clin Nutr, 99(3): 718s-722s.
36. Braga AL, Zanobetti A, Schwartz J (2002). The effect of weather on respiratory and cardiovascular deaths in 12 U.S. cities. Environ Health Perspect, 110(9): 859-863.
37. Guo Y, Barnett AG, Pan X, et al (2011). The impact of temperature on mortality in Tianjin, China: a case-crossover design with a distributed lag nonlinear model. Environ Health Perspect, 119(12): 1719-1725.
38. Hänninen O, Knol AB, Jantunen M, et al (2014). Environmental burden of disease in Europe: assessing nine risk factors in six countries. Environ Health Perspect, 122(5): 439-446.
| Files | ||
| Issue | Vol 51 No 6 (2022) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/ijph.v51i6.9671 | |
| Keywords | ||
| Plastic greenhouse Microenvironment Body trace element Immune globulin | ||
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How to Cite
1.
Li H, Li J, Sun W, Dong L, Zhu L, Jiang Z, Yang H. Association between Indoor Environment, Blood Trace Elements, and Immune Globulin among Workers from Vegetables Plastic Greenhouses in Yinchuan, China. Iran J Public Health. 2022;51(6):1274-1282.
