Association between Human Papillomavirus and Oral Cancer in Iranian Clinical Samples: A Meta-Analysis Review
-
Mohammad Reza Haghshenas
,
Mahmood Moosazadeh
,
Saeid Taghiloo
,
Sogol Sattari
,
Reza Valadan
,
Tahoora Mousavi
Abstract
Background: Oral squamous cell carcinoma (OSCC) is one of the most common malignancies and is a serious problem worldwide. The role of HPV in oral cavity squamous cell carcinoma has been studied in several researches. This present review and meta-analysis aimed to investigate the relation between human papillomavirus (HPV) and oral cancer.
Methods: Relevant studies were found using online international databases including Science direct, Web of science (ISI), PubMed, Scopus, Embase, and Google scholar, to determine relevant studies published between 2000 and Jan 2020. Suitable studies were selected and assessed by two independent researchers. The quality of all papers were determined by a checklist. Heterogeneity assay among the primary studies was evaluated by Cochran's Q test and I2 index. The statistical analyses were done using Stata SE, V.11 software. Trim and Fill method was applied to confirm the validity of the results.
Results: This meta-analysis consists of 8 primary studies on the incidence of HPV infection in Iranian patients with oral diseases. The odds ratio between HPV infection and risk of oral cancer was 4.00 (95%CI: 2.31, 6.93).
Conclusion: This meta-analysis showed associations between prevalence of HPV infection and oral cancer among Iranian patients. The chance of developing oral cancer among HPV positive patients was higher than that in HPV negative patients.
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20. Mokhtari-Azad T, Moradi A, Khodayari-Nemin A, et al (2006). Detection of human papillomavirus DNA in intraosseus ameloblastoma. Int J Virol, 2(1):1-6.
21. Tabatabai SH, Nabieyan M, Sheikhha MH, Zarmehi S, Tadbir AA, Ahmadi NA (2015). Detection of Human papillomavirus 16 and 18 types in oral squamous cell carcinoma patients in Yazd, Iran: A Case-Control Study. J Paramed Sci, 6(1):11-17.
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26. Bukhari N, Joseph JP, Hussain J, et al (2019). Prevalence of human papilloma virus sub genotypes following head and neck squamous cell carcinomas in asian continent, a systematic review Article. Asian Pac J Cancer Prev, 20(11):3269.
27. Pinzon LM, Velazquez A, Rutkoski H, et al (2022). Cross-cultural adaptation of a Spanish version of a previously validated HPV survey that evaluates dental students’ knowledge, perception and clinical practices in Latin America. BMC Oral Health, 22(1):1-8.
28. Carlander AF, Jakobsen KK, Bendtsen SK, et al (2021). A contemporary systematic review on repartition of HPV-positivity in oropharyngeal cancer worldwide. Viruses, 9;13(7):1326.
29. Nikakhlagh S, Saki N, Shoar MH, Sartipipor A, Saki S (2012). Incidence of etiologic factors in squamous cell carcinoma of head and neck in Ahvaz. Iran J Otorhinolaryngol, 24(67):85-90.
30. Delavarian Z, Pakfetrat A, Falaki F, Pazouki M, Pazouki N (2010). The role of viruses in oral squamous cell carcinoma in young patients in Khorasan (Northeast of Iran). J Appl Sci, 10(11):981-5.
31. Lee SY, Cho NH, Choi EC, et al (2010). Relevance of human papilloma virus (HPV) infection to carcinogenesis of oral tongue cancer. Int J Oral Maxillofac Surg, 39(7):678-83.
32. El-Salem F, Mansour M, Gitman M, et al (2019). Real-time PCR HPV genotyping in fine needle aspirations of metastatic head and neck squamous cell carcinoma: Exposing the limitations of conventional p16 immunostaining. Oral Oncol, 1;90:74-9.
33. Vidal Loustau AC, Dulguerov N, Curvoisier D, McKee T, Lombardi T (2019). Low prevalence of HPV‐induced oral squamous cell carcinoma in Geneva, Switzerland. Oral Dis, 25(5):1283-90.
34. Wu W, Wang Z, Zhou Z (2019). Role of the human papillomavirus in malignant transformation of oral leukoplakia distinct from oropharyngeal squamous cell carcinoma: A study of 76 patients with internal-control specimens. Oral Surg Oral Med Oral Pathol Oral Radiol, 1;128(3):273-9.
35. Méndez-Martínez R, Maldonado-Frías S, Vázquez-Vega S, et al (2020). High prevalent human papillomavirus infections of the oral cavity of asymptomatic HIV-positive men. BMC Infect Dis, 20(1):1-9.
2. Akhondnezhad M, Haghshenas MR, Ghasemi M, Mousavi T (2018). The prevalence and genotyping of human papillomavirus in patients with oral tumors in health centers and clinics of Mazandaran in Iran. Virusdisease, 29(3):297-302.
3. Sritippho T, Chotjumlong P, Iamaroon A. Roles of human papillomaviruses and p16 in oral cancer (2015). Asian Pac J Cancer Prev, 16(15):6193-200.
4. Sathish N, Wang X, Yuan Y. Human papillomavirus (HPV)-associated oral cancers and treatment strategies (2014). J Dent Res, 93(7_suppl):29S-36S.
5. Baniebrahimi G, Mir F, Khanmohammadi R. Cancer stem cells and oral cancer: insights into molecular mechanisms and therapeutic approaches (200). Cancer Cell Int, 20(1):1-5.
6. Wierzbicka M, San Giorgi MR, Dikkers FG. Transmission and clearance of human papillomavirus infection in the oral cavity and its role in oropharyngeal carcinoma–A review (2020). Rev Med Virol, 22:e2337.
7. Akram N, Imran M, Noreen M, Ahmed F, Atif M, Fatima Z, Bilal Waqar A (2017). Oncogenic role of tumor viruses in humans. Viral Immunol, 1;30(1):20-7.
8. Chen X, Zhao Y (2017). Human papillomavirus infection in oral potentially malignant disorders and cancer. Arch. Oral Biol, 83:334-9.
9. de Sanjosé S, Brotons M, Pavón MA (2018). The natural history of human papillomavirus infection. Best Pract Res Clin Obstet Gynaecol, 47:2-13.
10. Okunade KS (2020). Human papillomavirus and cervical cancer. J Obstetrics Gynaecol, 40(5):602-8.
11. Taberna M, Mena M, Pavón M, Alemany L, Gillison M, Mesía R (2017). Human papillomavirus-related oropharyngeal cancer. Ann Oncol, 28(10):2386-98.
12. Haghshenas MR, Mousavi T, Moosazadeh M, Afshari M (2016). Human papillomavirus and breast cancer in Iran: a meta-analysis. Iran J Basic Med Sci, 19(3):231.
13. Janecka-Widła A, Mucha-Małecka A, Majchrzyk K, Halaszka K, Przewoźnik M, Słonina D, Biesaga B (2020). Active HPV infection and its influence on survival in head and neck squamous-cell cancer. J Cancer Res Clin Oncol, 146(7):1677-92.
14. Shang Q, Peng J, Zhou Y, Chen Q, Xu H (2020). Association of human papillomavirus with oral lichen planus and oral leukoplakia: A meta-analysis. J Evid Based Dent Pract, 1;20(4):101485.
15. Von Elm E, Altman DG, Egger M, et al (2007). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Ann Intern Med, 147(8):573-7.
16. Ashraf MJ, Hosseini S, Monabati A, et al (2017). The prevalence of human papilloma virus in squamous cell carcinoma of oral tongue. Iran J Pathol, 12(2):144-149.
17. SahebJamee M, Boorghani M, Ghaffari SR, AtarbashiMoghadam F, Keyhani A (2009). Human papillomavirus in saliva of patients with oral squamous cell carcinoma. Med Oral Patol Oral Cir Bucal, 14(10):e525-8.
18. Saghravanian N, Ghazi N, Meshkat Z, Mohtasham N (2015). Human Papillomavirus in Oral Leukoplakia, Verrucous Carcinoma, Squamous Cell Carcinoma, and Normal Mucous Membrane. Oman Med J, 30(6):455-60.
19. Rahbarnia L, Farajnia S, Bayazian G, Naderpour M, Feizi H (2019). Prevalence of Human Papillomavirus in Patients With Oral Squamous Cell Carcinoma in Tabriz, Iran. Crescent J Med Biol Sci, 6(1):105-8.
20. Mokhtari-Azad T, Moradi A, Khodayari-Nemin A, et al (2006). Detection of human papillomavirus DNA in intraosseus ameloblastoma. Int J Virol, 2(1):1-6.
21. Tabatabai SH, Nabieyan M, Sheikhha MH, Zarmehi S, Tadbir AA, Ahmadi NA (2015). Detection of Human papillomavirus 16 and 18 types in oral squamous cell carcinoma patients in Yazd, Iran: A Case-Control Study. J Paramed Sci, 6(1):11-17.
22. Namin AK, Azad TM, Eslami B, Sarkarat F, Shahrokhi M, Kashanian F (2003). A study of the relationship between ameloblastoma and human papilloma virus. J Maxillofac Oral Surg, 61(4):467-70.
23. Saghravanian N, Ghazvini K, Babakoohi S, Firooz A, Mohtasham N (2011). Low prevalence of high risk genotypes of human papilloma virus in normal oral mucosa, oral leukoplakia and verrucous carcinoma. Acta Odontol Scand, 69(6):406-9.
24. Giraldi L, Collatuzzo G, Hashim D, et al (2021). Infection with Human Papilloma Virus (HPV) and risk of subsites within the oral cancer. Cancer Epidemiol, 1;75:102020.
25. Yete S, D'Souza W, Saranath D (2018). High-risk human papillomavirus in oral cancer: clinical implications. Oncology, 94(3):133-41.
26. Bukhari N, Joseph JP, Hussain J, et al (2019). Prevalence of human papilloma virus sub genotypes following head and neck squamous cell carcinomas in asian continent, a systematic review Article. Asian Pac J Cancer Prev, 20(11):3269.
27. Pinzon LM, Velazquez A, Rutkoski H, et al (2022). Cross-cultural adaptation of a Spanish version of a previously validated HPV survey that evaluates dental students’ knowledge, perception and clinical practices in Latin America. BMC Oral Health, 22(1):1-8.
28. Carlander AF, Jakobsen KK, Bendtsen SK, et al (2021). A contemporary systematic review on repartition of HPV-positivity in oropharyngeal cancer worldwide. Viruses, 9;13(7):1326.
29. Nikakhlagh S, Saki N, Shoar MH, Sartipipor A, Saki S (2012). Incidence of etiologic factors in squamous cell carcinoma of head and neck in Ahvaz. Iran J Otorhinolaryngol, 24(67):85-90.
30. Delavarian Z, Pakfetrat A, Falaki F, Pazouki M, Pazouki N (2010). The role of viruses in oral squamous cell carcinoma in young patients in Khorasan (Northeast of Iran). J Appl Sci, 10(11):981-5.
31. Lee SY, Cho NH, Choi EC, et al (2010). Relevance of human papilloma virus (HPV) infection to carcinogenesis of oral tongue cancer. Int J Oral Maxillofac Surg, 39(7):678-83.
32. El-Salem F, Mansour M, Gitman M, et al (2019). Real-time PCR HPV genotyping in fine needle aspirations of metastatic head and neck squamous cell carcinoma: Exposing the limitations of conventional p16 immunostaining. Oral Oncol, 1;90:74-9.
33. Vidal Loustau AC, Dulguerov N, Curvoisier D, McKee T, Lombardi T (2019). Low prevalence of HPV‐induced oral squamous cell carcinoma in Geneva, Switzerland. Oral Dis, 25(5):1283-90.
34. Wu W, Wang Z, Zhou Z (2019). Role of the human papillomavirus in malignant transformation of oral leukoplakia distinct from oropharyngeal squamous cell carcinoma: A study of 76 patients with internal-control specimens. Oral Surg Oral Med Oral Pathol Oral Radiol, 1;128(3):273-9.
35. Méndez-Martínez R, Maldonado-Frías S, Vázquez-Vega S, et al (2020). High prevalent human papillomavirus infections of the oral cavity of asymptomatic HIV-positive men. BMC Infect Dis, 20(1):1-9.
| Files | ||
| Issue | Vol 51 No 12 (2022) | |
| Section | Review Article(s) | |
| DOI | https://doi.org/10.18502/ijph.v51i12.11459 | |
| Keywords | ||
| Oral cancer Iran Human papillomavirus | ||
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How to Cite
1.
Haghshenas MR, Moosazadeh M, Taghiloo S, Sattari S, Valadan R, Mousavi T. Association between Human Papillomavirus and Oral Cancer in Iranian Clinical Samples: A Meta-Analysis Review. Iran J Public Health. 2022;51(12):2688-2696.
