Evaluation of the Effect of Macronutrients Combination on Blood Sugar Levels in Healthy Individuals
Abstract
Background: The positive effects of blood glucose levels should be demonstrated in healthy or type 2 diabetic individuals who can be recommended to consume macronutrients (protein + fat) with carbohydrates. Therefore, at the end of the research planned with the amount of carbohydrates and fats that can be consumed in a meal, we aimed to recommend the consumption of food with high protein content egg together with the carbohydrate source.
Methods: The study was carried out from Nov 2017 to Apr 2018 by looking at fasting blood glucose levels using feeding 2 different test foods on a minimum of 8 h of fasting in the Haliç University Sutluce Campus, Istanbul, Turkey. Before and after the carbohydrate and carbohydrate + protein source, blood glucose was measured from the fingertip for 3 days in 30 min, 60 min and 120 min periods. The average of 3 days was used in the analysis.
Results: Blood glucose values were compared after individuals were given carbohydrate and carbohydrate + protein source. The mean blood glucose value 60 min after the carbohydrate administration was significantly higher than the average blood glucose value 60 min after the carbohydrate + protein administration (P= 0.006
Conclusion: A protein-containing diet positively affects the glycemia response and can recommend it. In individuals with diabetes, they should focus on the effects of proteins to achieve glycemia control.
2. Jenkins DJ, Kendall CW, Augustin LS, et al (2002). Effect of wheat bran on glycemic control and risk factors for cardiovascu-lar disease in type 2 diabetes. Diabetes Care, 25(9): 1522-8.
3. Jenkins DJ, Kendall CW, Augustin LS, et al (2002). Glycemic index: overview of im-plications in health and disease. Am J Clin Nutr, 76(1):266S-73S.
4. Azzout-Marniche D, Gaudichon C, Tomé D (2014). Dietary protein and blood glu-cose control. Curr Opin Clin Nutr Metab Care, 17(4): 349- 54.
5. Nuttall FQ, Gannon MC (2013). Dietary protein and the blood glucose concentra-tion. Diabetes, 62(5): 1371-1372.
6. Nansel TR, Gellar L, McGill A (2008). Ef-fect of varying glycemic index meals on blood glucose control assessed with con-tinuous glucose monitoring in youth with type 1 diabetes on basal-bolus insulin regimens. Diabetes care, 31(4):695-7.
7. Goossens GH, Blaak EE, Amer P, et al (2007). Angiotensin II: A Hormone That Affects Lipid Metabolism İn Adipose Tissue. Int J Obes (Lond), 31(2):382-4.
8. Karakoc E, Yalcin BM, Yalcin E (2017). The comparison of insulin levels between over weighted and non-obese smokers. Journal of Experimental & Clinical Medicine, 34(1): 67-71.
9. Savas HB, Gultekin F (2017). Insulin re-sistance and clinical significance. Med J SDU, 24(3):116-125.
10. Bozbulut R, Sanlıer N (2016). The effect of dietary fat, protein and glycemic index on glycemic control and its use in insulin ap-plications in Type 1 Diabetes. Turkey Clin-ical J Endocrin,11(2): 46-54.
11. Ekici M, Nergiz-Unal R (2017). Association Between Insulin Resistance, Nutrition, Fatty Meal Desire and CD36 Receptor. Turkish Journal of Agriculture: Food Science and Technology, 5(9): 1108-1118.
12. Hsueh WA, Orloski L, Wyne K (2010). Pre-diabetes: the importance of early identifi-cation and intervention. Postgrad Med, 122(4): 129-43.
13. Kitiş Y, Bilgili N, Hisar F, et al (2010). Preva-lence of metabolic syndrome in women aged 20 and above and factors affecting it. Anatolian J Cardiology:10(2).
14. Erin E Kershaw, Jeffrey S Flier (2004). Adi-pose tissue as an endocrine organ. J Clin Endocrinol Metab, 89(6):2548-56.
15. Bao J, Atkinson F, Petocz P, et al (2011). Prediction of postprandial glycemia and insulinemia in lean, young, healthy adults: glycemic load compared with carbohy-drate content alone. Am J Clin Nutr, 93(5): 984-96.
16. He T, Giuseppin ML (2014). Slow and fast dietary proteins differentially modulate postprandial metabolism. Int J Food Sci Nutr, 65(3): 386-90.
17. Moghaddam E, Vogt JA, Wolever TM (2006). The effects of fat and protein on glycemic responses in nondiabetic hu-mans vary with waist circumference, fast-ing plasma insulin, and dietary fiber in-take. J Nutr, 136(10): 2506-11.
18. Lodi A, Karsten B, Bosco G, et al (2016). The effects of different high-protein low-carbohydrates proprietary foods on blood sugar in healthy subjects. J Med Food, 19(11): 1085-1095.
19. Angela L, Bonnema AL, Altschwager BDK, et al (2016). The effects of the combina-tion of egg and fiber on appetite, glyce-mic response and food intake in normal weight adults – a randomized, controlled, crossover trial. Int J Food Sci Nutr, 67(6): 723-31.
Files | ||
Issue | Vol 50 No 2 (2021) | |
Section | Original Article(s) | |
DOI | https://doi.org/10.18502/ijph.v50i2.5340 | |
PMCID | PMC7956086 | |
PMID | 33747991 | |
Keywords | ||
Carbohydrate Protein Fasting blood sugar Glycemic response |
Rights and permissions | |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |