First Cases of SARS-CoV-2 in Iran, 2020: Case Series Report

  • Jila Yavarian Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Nazanin-zahra Shafiei-jandaghi Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Kaveh Sadeghi Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Somayeh Shatizadeh Malekshahi Department of Virology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
  • Vahid Salimi Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Ahmad Nejati Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Fatemeh Ajaminejad Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Nastaran Ghavvami Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Fatemeh Saadatmand Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Saeedeh Mahfouzi Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Ghazal Fateminasab
  • Najmeh Parhizgari Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Akramsadat Ahmadi Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Kobra Razavi Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Soad Ghabeshi Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Mostafa Saberian Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  • Elham Zanjani Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  • Fatemeh Namazi School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
  • Tayebeh Shahbazi Department of Bacteriology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
  • Farshid Rezaie Iranian Center for Communicable Disease Control, Tehran, Iran
  • Hosseinn Erfani Iranian Center for Communicable Disease Control, Tehran, Iran
  • Mohammad Mehdi Gouya Iranian Center for Communicable Disease Control, Tehran, Iran
  • Mohammad Nasr Dadras Iranian Center for Communicable Disease Control, Tehran, Iran
  • Talat Mokhtari-azad Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Keywords:
SARS-CoV-2, Iran, Emerging disease, Virus, COVID-19

Abstract

In Jan 2020, the outbreak of the 2019 novel coronavirus (SARS-CoV-2) in Wuhan, Hubei Province of China spread increasingly to other countries worldwide which WHO declared it as a public health emergency of international concern. Iran was included in the affected countries. Throat swab specimens were collected and tested by using real-time reverse transcription PCR (RT-PCR) kit targeting the E region for screening and RNA dependent RNA polymerase for confirmation. Conventional RT-PCR was conducted for the N region and the PCR products were sequenced by Sanger sequencing. The first seven cases of SARS-CoV-2 infections were identified in Qom, Iran. This report describes the clinical and epidemiological features of the first cases of SARS-CoV-2 confirmed in Iran. Future research should focus on finding the routes of transmission for this virus, including the possibility of transmission from foreign tourists to identify the possible origin of SARS-CoV-2 outbreak in Iran.

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Published
2020-07-30
How to Cite
1.
Yavarian J, Shafiei-jandaghi N- zahra, Sadeghi K, Shatizadeh Malekshahi S, Salimi V, Nejati A, Ajaminejad F, Ghavvami N, Saadatmand F, Mahfouzi S, Fateminasab G, Parhizgari N, Ahmadi A, Razavi K, Ghabeshi S, Saberian M, Zanjani E, Namazi F, Shahbazi T, Rezaie F, Erfani H, Mehdi Gouya M, Nasr Dadras M, Mokhtari-azad T. First Cases of SARS-CoV-2 in Iran, 2020: Case Series Report. Iran J Public Health. 49(8):1564-1568.
Section
Case Report(s)