2023 Impact Factor: 1.3
2023 CiteScore: 2.2
pISSN: 2251-6085
eISSN: 2251-6093
Chairman & Editor-in-Chief:
Dariush D. Farhud, MD, Ph.D., MG.
This journal is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE). 
Vol 16 No 1-4 (1987)
Articles
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A group of Iranian patients suffering from Factor VIII deficiency (Hemophilia A) and treated with contaminated coagulation factor (imported), became seropositive as determined by ELISA method. Sixty of these individuals, which were available, were studied for ABO distribution. The B blood group in anti HIV pos. individuals (13.33%) shows a significant decrease in comparison with the total (1504) of factor VIII hemophilia (21.87%). Statistical analysis of ABO distribution in anti HIV Pos. compared with hemophilia A and the control group showed x2 values of 6.86(0.10 > p>0.05) and 10.21(0.02> P >0.01) respectively.
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Current sampling instruments of respirable dust (RD) may over estimate the inhaled dose by up to 400% depending on the size distribution of airborne dust. This limitation and the practice of assigning a single value for RD to all jobs regardless of the level of activity are incompatible with the advances in occupational epidemiology. A new dust sampler designed to estimate pulmonary deposition (PD) was developed to alleviate these limitations. The device consists of a 10 mm diameter microscope cover slip. Estimation of PD is obtained by selecting the appropriate air flow rate and diameter of impactor so that the combined performance will simulate the bell shaped curves of PD at various respiratory frequencies and tidal volumes. To obtain better matching of PD, this configuration was selected, rather than two impactors in series, (impactors have sharp cut- off curves). A cyclone can also collect large amounts of the sampler wax evaluated using monodispersed aerosols 1.1, 2.7, 4.7, 9.8, um and geometric standard deviations 1.2. The results indicate that PD is estimated very closely by the new sampler.
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Human chromosomes in amnion cells and lymphocytes with normal karyotype and in lymphocytes with pathological karyotype (2n=47, +21) were compared as to their position in the metaphase. None of the collectives showed sex differences. Measurement of the radial distances revealed more peripheral position of the majority of large chromosomes. The satellite-carrying chromosomes of the D group always had a central position in the mitosis. The chromosomes of the groups D, E, F and G were closest to the centre; with the exception of chromosome 18 which was peripheral in all three collectives. For the male probands, the y-chromosome was shown in all three collectives to have a smaller radial distance than the x-chromosome. A typical distribution was found for the radial and homologue distances for the trisomic cells, two of them had a very large radial distance, the third a value corresponding to its size. For the homolarger measurements hereby the distribution is quite independent of parental source. Comparison of the groups showed no differences either between normal and trisomy cells or between the different cell types. Examination of chromosomes 6 and 15 proved conclusively that the chromosomes are not particularly orientated in the c-metaphase regarding the position of short and long arm. A preferential combination of particular satellite carrying chromosomes leads to the frequent fusions of chromosomes 13 and 14, or 14 and 21. Equally, no preferential association could be demonstrated of the chromosome 21 and the chromosomes with large heterochromatin blocks in the centromere region (chromosomes 1 and 9). The distances were of the same order of magnitude as those between 21 and chromosome 6, a submetacentric chromosome without a marked heterochromatin region. Both latter observations are of specific importance for genetic councelling of couples after birth of a child with a de Novo chromosome aberration asking for the recurrence risk.
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Reproductive behavior of 1525 pregnant woman were studied in the time of termination of pregnancy in relation to maternal age, education, prenatal care and the number of previous pregnancies. The results show that the frequency of maternal attendance at the centers of prenatal care is significantly related to maternal education. And the total pregnancies per woman are inversely correlated with maternal education. The kind of termination of pregnancy which resulted in live births or abortion have significant relation to maternal age such a way that the highest percentage of abortion observed in the age group of 15-19 ; and the highest number of natural deliveries has been in the age group of 20-29.
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Two isolates of Trichinella were obtained from the jackal, Canis aureus: one from the north Caspian area, the other from the south-west Khuzestan area of Iran. The infectivity of the isolates was tested in laboratory animals, in a wild rodent (Tatera indica) and in wild pigs. The isolate from Khuzestan was of low infectivity to albino rats and it was provisionally identified as Trichinella nelsoni. The Caspian isolate was highly infective for albino rats and wild pigs and was identified as Trichinella spiralis.
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Different examination have shown that rheumatoid factor is not responsible for false positive reaction (F.P.R.) in Cr. Neoformanse’s free capsular antigen latex agglutination test, whereas high levels of iron in sera of patients with rheumatoid arthritis as well as other sera was responsible not only for this F.P.R. , but also had an important role in the production of F.P.R. in many slide latex agglutination tests. This is because of Iron’s Ion reaction with reagent’s preservative: sodium azid and/or negative charge of the antigens fixed to the latex particles.
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Antibiotic resistance in Shigella species has been showing a rising trend all over the world. This study was performed to discover the state of antibiotic resistance of Shigella species with regards to six common antibiotics in use in Iran.
