Articles

• IMMUNE RESPONSES IN ESOPHAGEAL CARCINOMA EC PATIENTS

  S. Hashemi , B. Parhami , M.S. Enayat , K. Dowlatshahi , N.E. Day , N. Mohagheghpour

  XML | PDF | downloads: 51 | views: 92 | pages: 121-134

  Abstract

  General immune responses were studied in patients with esophageal carcinoma (EC) and were compared to those in normal individuals of similar age, sex and ethnic origin. There was a significant increase in the titer of "background” antibodies in the sera of cancer patients; however, this elevation was not associated with an increase in the levels of serum immunoglobulin. EC patients had a diminished number of E rosetting lymphocytes but normal proportion of EAC rosetting cells. Lymphocytes from a small but significant number of patients showed decreased responses to PHA when cultured in medium containing fetal calf serum. Plasma sample from these patients were capable of inhibiting the in vitro proliferate responses of lymphocytes to PPD.
• ISOLATION AND PURIFICATION OF LECTIN FROM IRANIAN RICINUS COMMUNIS SEEDS

  Badri Tavasolian , S Mottaghian

  XML | PDF | downloads: 83 | views: 140 | pages: 145-154

  Abstract

  Iranian castor bean lectin was isolated and purified by several column chromatography methods. Then, the sugar and amino acid content of the purified lectin was identified. Castor bean lectin has some anti tumor and anti leukemia action. Thus it may be used commercially for medical and biochemical purposes.
• EFFECT OF FAVA BEAN EXTRACTS ON THE ERYTHROCYTE POTASSIUM TO HEMOGLOBIN RATION IN NORMAL SUBJECTS AND G6PD DEFICEICY PATIENTS

  M. Rahmanian , M. Sadre , G. Donoso , H. Ghassemi , O. Mickelsen

  XML | PDF | downloads: 54 | views: 107 | pages: 155-164

  Abstract

  A procedure for the in vitro evaluation of the toxicity of fava beans has been applied to 17 varieties of the bean and one batch of beans purchased on the open market; the latter consisted of unknown varieties. The procedure involves the incubation of a saline extract of the beans with red cells from normal individuals and with red cells from G6PD deficient patients. 2. Normal red cells under those circumstances absorb potassium from the fava bean extract whereas the cells from G6PD deficient patients lose potassium. 3. This work suggest a relation between the toxicity of the fava beans and the lose of potassium by the red cells. On the basis of this assay, it appears that two of the 17 varieties may be non-toxic.