2023 Impact Factor: 1.3
2023 CiteScore: 2.2
pISSN: 2251-6085
eISSN: 2251-6093
Chairman & Editor-in-Chief:
Dariush D. Farhud, MD, Ph.D., MG.
This journal is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE). 
Vol 5 No 1 (1976)
Articles
-
A total of 1,497 serum and blood specimens from residents of 18 different Iranian communities were examined by plaque reduction neutralization test for antibodies against four (Neaples, Sicilian, Karimabad and Salehabad) Phlebotomus fever virus serotypes. Neutralizing antibodies against the Naples and Sicilian serotypes were found in every community sampled, indicating that these viruses are widely distributed in the country. In contrast, Karimabad antibodies were restricted mainly to residents of Isfahan, Tehran and Khorassan Provinces. No evidence of human infection with Salehabad virus was found. Results of this study indicate that the frequency of human infection with Phlebotomus fever viruses is high in Iran. The symptoms of sand fly fever are also reviewed.
-
A total of 698 blood and serum specimens from residents of 13 Iranian communities were examined by plaque reduction neutralization test for antibodies to West Nile virus. In general, infection rates in the north of the country were low while higher rates were observed among residents of central and southwestern Iran. The highest prevalence of infection was found among residents of Khuzestan province, indicating that this region is one of endemic West Nile virus activity. The symptoms of west Nile virus infection in man are also discussed.
-
The levels of serum tota1 protein, albumin, transaminases and phosphatases were estimated in a group of children with severe Marasmus or mild malnutrition in order to identify some of the associated deficiencies in these syndromes. The biochemical pattern was similar in the normal and malnourished children.
-
In a series of heterologous immunity studies S. haematobium, S. bovis and O. turkestanicum in calves, a large number of S. haematobium cercariae (21,000 cercariae) were used repeatedly as the immunization agent. At autopsy, 22 weeks after initial exposure, immature S. haematobium was detected. Thirteen weeks after initial exposure a group of calves was challenged with S. bovis and another group with O. turkestanicum cercariae. The resu1t of this investigation showed that the calves had developed limited S. haematobium infections. The number of worms recovered by perfusion varied from 250 to 640 (378±99) and the mean percentage of worms recovered was 1.8%. Most of the worms were found in the portal veins, but in one calf some larger worms were detected in the lower mesenteric veins of the large intestine with some reformatted eggs in the caecum substances. No worms or eggs were found in the vesicle plexus or bladder tissue. The immune response which developed in calves with S. haematobium infection was considerable. The protective effects of immunity were measured by detecting the effects on the expected worm burden and tissue egg counts of the challenge infection compared with the control group. It was found that the mean reduction of worm recovery and tissue egg counts was 42.3% and 62.2% in group S. haematobium versus S. bovis, and 31.4% and 81.0% in group S. haematobium versus O. turkestanicum infection. This suggests that the immune phenomen will occur in endemic areas like Khuzestan, Iran, and that under natural conditions this might reduce the severity of the disease in livestock.
-
A two-year laboratory study on the biology (including self-fertilization) of Bulinus truncatus, the intermediate host of Schistosoma haematobium, S. bovis and Paramphistomum microbotrium in Iran, has revealed information on the longevity, reproduction, hatchability rate, hatching time during various months of the year, and growth and mortality rates of this snail. It was found that the reproduction, hatchability and growth rate of Bulinus truncatus increase under condition of self-fertilization.
