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pISSN: 2251-6085
eISSN: 2251-6093
Chairman & Editor-in-Chief:
Dariush D. Farhud, MD, Ph.D., MG.
This journal is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE). 
Vol 2 No 2 (1973)
Articles
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A study was undertaken to find out the prevalence rate or rheumatic fever (R.F.) and rheumatic heart disease (R.H.D.) among pupils in selected schools of Tehran, and to evaluate the rate of socio-economical factors on prevalence rate of this disease. During period of 5 months, 6, 183 children and adolescents aged 5-17 were studied. Out of 6,183 pupils, 3, 680 were boys (59.5) and 2,503 were girls (40.5%). 1,425(23%) were in high, 1,381 (22%) in mid, and (55%) in low socio- economic classes. Out of these, 32 (5.2/per 1000) had history of R.F. in the past and 17 (2.7/per 1000) had R.H.D. with an all together prevalence rate of 7.9/per 1000. There was no significant difference in the prevalence rate of rheumatic fever and rheumatic heart disease between the children in high and low socioeconomic group.
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One hundred and eight male (108) cases, which have been using Lippes Loops (I.U.D.) for contraception, were followed for five (+5) years, and unwanted pregnancies and side effects were analyzed. Our over all impression is that because of the frequency of uterine bleeding which they cause, Lippes Loops are not an ideal contraceptive method for Iranian women.
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The resistance of Plasmodium falciparum to 4-amioquinolines has been confirmed in parts of South America such as Venezuela, Colombia, Brazil and Panama since 1961. During 1968-1970, 147 P. falciparum cases in the Kazeroon and Bandar Abbas areas were tested against 4-aminoquinolines, bases on 25 mg Resochin /kg of body weight over a period of 3 days. Twenty–foure, 48 , 72 and 96 hours after drug administration, the parasitemia rate was 80.5, 24.8, 1.65 and 0 per cennt, respectively . Blood samples taken from the subjects showed no asexual parasitemia for up to 28 days. Tests were carried out by the two – stage and single – stage methods (WHO, 1965 , 1967).The subjects were observed daily for 7 days after drug administration and then weekly for up to 4 weeks. Urine samples were taken and examined for chloroqine by days, one subject showed parasitemia. He was re-treated with 4-aminoquinolines and his blood was cleared of asexual parasites after the administration of 1500 mg of chloroqine.These studies showed that the local strain of P. falciparum in this area was susceptible to chloroqine.
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Because of possible increase in the incidence of Brucellosis in the city Ghom , serological and bacteriological studies were conducted to investigate the rate of infection in this city. A total of 819 blood samples from Human , “suspected” cases were investigated (serologically) 121 of these were positive for brucellosis ,(14/6%).Of 182 samples of milk collected from cattle 50 were positive (27/5%). Serological test performed on 122 samples from cattle, goats and sheep cases were positive for brucellosis, (40%). The above study no doubt indicates that there is a high rate of human and animal infection with brucellosis in the city Ghom.
