2023 Impact Factor: 1.3
2023 CiteScore: 2.2
pISSN: 2251-6085
eISSN: 2251-6093
Chairman & Editor-in-Chief:
Dariush D. Farhud, MD, Ph.D., MG.
This journal is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE). 
Vol 3 No 2 (1974)
Articles
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With the recent changes in the status of malaria and in the strategy of malaria eradication, and with more emphasis given to the planning of .the anti-malarial campaign within a coordinated health and socio-economic development plan; with the, betterment of methodology for comprehensive health planning and the refinement of administration and management techniques; and with rapidly increasing medical knowledge and technology; there is need for a revision of the programs for the training of the professional malaria staff, particu1arly the "malariologist".In the present paper, the above changes and developments as well as the experience gained are reviewed, the profile of an ideal epidemiologist malariologist is given, and the pattern of the program for the training of such a person, including basic, special and advanced training, is described and, wherever necessary, is exemplified.
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A total of 711 beta-hemolytic streptococci were isolated from throat cultures of patients during 1970-73. These strains were grouped in parallel by the precipitin and bacitracin paper disk method. The former method was established as the standard by which the bacitracin technique was compared. The difference in results was about 5.67%. The greatest error (5.4%) was seen with non-group A strains being sensitive to bacitracin. In spite of this, it was shown to be advantageous to use the bacitracin disk for primary isolation from throat cultures rather than to consider all beta-hemolytic streptococci isolated as group A, which would give a magnitude of error around 16%.
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One hundred sera from children 1 - 6 years of age, representative of a large serum collection, were tested for the prevalence of antibodies against different viruses. Hemagglutination-inhibition (HI) antibodies were found in 68% for measles; 61 % for rubella; 75'% for influenza A2/Hong Kong/68, 16% for influenza B/Md./59, 0% for group A arboviruses, 10% for group B arboviruses, 3% for phlebotomus fever group and 4% for Congo-Crimean hemorrhagic fever (C-CHF) group of arboviruses Poliomyelitis-neutralizing antibodies for type 1, 2 and 3 were 90%; 85% and 84%~ respectively. Antibody to EH virus was detected in 84% of the sera by immuno-fluorescence. None of the sera were positive for hepatitis-B antigen or antibody by immuno-precipitation test. The prevalence of some viral antibodies found in this survey are compared with results obtained from surveys in other parts of the country.
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The effect of a new anthelmintic compound, Leavo-tetramisole, in the mass-treatment of several intestinal helminthes has been evaluated during a study undertaken among the population of the village of Zavieh Hajian, located about 10 km northwest of Dezful, Khuzestan.In the autumn of 1972, a total of 83 inhabitants, 65 of whom were simultaneously infected with Ascaris, hookworm (Ancylostoma) and Trichostrongylus spp. and 18 of whom where infected with the first two helminthes only, were treated with 40 mg tablets of the drug., The drug was given in a single dose of one tablet to the age group below 6, two tablets to the age group 6-15 and 3 tablets to adults. A group of 61 patients was kept as a control. Administration of the drug resulted in cure rates of 98.8% for Ascaris, 95.2% for Ancylostoma and 93.9% for trichostrongylus:, The reduction in the mean number of eggs among remaining cases was very high Low intensity side-effects, which were encountered among 20% of treated cases only, included, in order of frequency abdominal pain, headache, vertigo and vomiting. The high efficacy of this drug on 3 species of helminthes prevalent in the area, together with ifs effect in a single dose, make it the drug of choice for the mass-treatment of patients infected with helminthiasis in the southwestern part of Iran.
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The effect of dietary sucrose on DNA formation in rat liver and kidney compared with that of starch was studied. Male, weanling rats were fed for 6 and 14 days on diets containing 68% 'sucrose or 68% starch, and liver and kidneys were examined for 1ilie amount and rate of formation of DNA; and also for content of fat, protein, and moisture. Food intake and weight gain were estimated. Sucrose fed animals had heavier liver and kidneys than starch fed animals. Food intake and weight gain were similar on both diets. The enlargement of the liver after six days was mainly due to increase in1cell number calculated from DNA content. Whereas, after 14 days, the enlargement was mostly due to incensement of cell size. The proportion of protein and moisture in the liver of sucrose fed animals was less than in the starch fed ones, whereas fat content was 25'% higher. Sucrose feeding had no effect in six days on weight of kidneys, but after 14 days heavier kidneys were produced. Exemption of cortex showed no difference in cell number or cell size. Twenty-four hours before killing the animals were injected intraperitoneally with H3 thymidine. Radioactive count was too low, the results too variable for any conclusions to be drawn.
