Review Article

Determination the Research Priorities in the Field of HIV/AIDS in Iran: A Systematic Review Article


Background: HIV and AIDS have many different epidemiological, social and political aspects. The aim of this study was to determine the research priorities according to the necessary aspects of HIV and AIDS in Iran.

Methods: The national and international databases were searched to obtain the published articles regarding HIV and AIDS in Iran. All Epidemiologic studies were included in this review for assess research priorities.

Results: Of 3059 retrieved references, 362 studies were included. The most studies were conducted in Tehran, Kermanshah, Fars and Kerman provinces. The cross-sectional studies with 71.55% have higher proportion. Studies related to adherence to treatment (0.55%), drug resistance (0.83%) and experience, perception and behavior of HIV/AIDS patients (0.83%) had the lowest proportion of conducted studies. Proportion of studies regarding prevention of HIV was 2.76%. The authors of studies on female sex workers (FSWs) (63.64%) and prisoners (58.82%) suggested further studies on these groups.

Conclusion: According to our results, the high-risk groups such as female sex workers, injecting drug users and prisoners are in priority for research. Moreover, topics related to the prevention of HIV and AIDS, adherence to treatment and antiretroviral drug resistance are other research priorities in Iran.



Fauci AS (2003). HIV and AIDS: 20 years of science. Nat Med, 9:839-843.

Moreno CL (2007). The relationship between culture, gender, structural factors, abuse, trauma, and HIV/AIDS for Latinas. Qual Health Res, 17:340-352.

World Health Organization HIV/AIDS [cited 13 April 2015]. Available from:

UNAIDS Global report: UNAIDS report on the global AIDS epidemic 2013. Geneva.

Haghdoost AA, Mostafavi E, Mirzazadeh A, Navadeh S, Feizzadeh A, Fahimfar N, Kamali K, Namdari H, Sedaghat A, Gooya M (2011). Modelling of HIV/AIDS in Iran up to 2014. J AIDS HIV Res, 3:231-239.

UNAIDS HIV and AIDS estimates (2013) [cited April 14, 2015]. Available from:

Feizzadeh A, Nedjat S, Asghari S, Keshtkar A, Heshmat R, Setayesh H, Majdzadeh R (2010). Evidence-based approach to HIV/AIDS policy and research prioritization in the Islamic Republic of Iran. East Mediterr Health J, 16:259-265.

Mavedzenge SN, Baggaley R, Corbett EL (2013). A review of self-testing for HIV: research and policy priorities in a new era of HIV prevention. Clin Infect Dis, 57:126-138.

Kelley K, Clark B, Brown V, Sitzia J (2003). Good practice in the conduct and reporting of survey research. Int J Qual Health Care, 15:261-266.

Kelly JA, Somlai AM, DiFranceisco WJ, Otto-Salaj LL, McAuliffe TL, Hackl KL, Heckman TG, Holtgrave DR, Rompa D (2000). Bridging the gap between the science and service of HIV prevention: Transferring effective research-based HIV prevention interventions to community AIDS service providers. Am J Public Health, 90:1082-8.

Haghdoost A, Sadeghi M, Nasirian M, Mirzazadeh A, Navadeh S (2012). Research priorities in the field of HIV and AIDS in Iran. J Res Med Sci, 17:481-6.

Mirzazadeh A, Nedjat S, Navadeh S, Haghdoost A, Mansournia M-A, McFarland W, Mohammad K (2014). HIV and related risk behaviors among female sex workers in Iran: bias-adjusted estimates from the 2010 National Bio-Behavoral Survey. AIDS Behav, 18:S19-24.

Razani N, Mohraz M, Kheirandish P, Malekinejad M, Malekafzali H, Mokri A, McFarland W, Rutherford G (2007). HIV risk behavior among injection drug users in Tehran, Iran. Addiction, 102:1472-1482.

Tabarsi P, Baghaei P, Mirsaeidi M, Amiri M, Alipanah N, Emami H, Novin A, Mansouri D, Masjedi MR, Velayati AA (2008). Treatment outcome of tuberculosis patients diagnosed with human immunodeficiency virus infection in Iran. Saudi Med J, 29:148-150.

Tabarsi P, Chitsaz E, Moradi A, Baghaei P, Farnia P, Marjani M, Shamai M, Amiri M, Nikaein S, Mansouri D, Masjedi M, Altice F (2012). Treatment outcome, mortality and their predictors among HIV-associated tuberculosis patients. Int J STD AIDS, 23:e1-e4.

Mannheimer S, Matts J, Telzak E, Chesney M, Child C, Wu A, Friedland G (2005). Quality of life in HIV-infected individuals receiving antiretroviral therapy is related to adherence. AIDS Care, 17:10-22.

World Health Organization (2013). Consolidated guidelines on general HIV care and the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach. WHO, Geneva

Krefting L (1991). Rigor in qualitative research: The assessment of trustworthiness. Am J Occup Ther, 45:214-222.

Kaptchuk TJ (2001). The double-blind, randomized, placebo-controlled trial: gold standard or golden calf? J Clin Epidemiol, 54:541-549.

Szklo M, Nieto FJ (2012). Epidemiology: beyond the basics. ed. Jones & Bartlett Publishers.

Borenstein M, Hedges LV, Higgins JP, Rothstein HR (2011). Introduction to meta-analysis. ed. John Wiley & Sons, UK.

Haghdoost AA, Pourkhandani A, Motaghipisheh SH, Farhoudi B, Fahimifar N, Sadeghirad B (2011). Knowledge and attitude concerning HIV/AIDS among Iranian population: A systematic review and meta- analysis. Iran J Epidemiol, 6:8-20.

Mardani A, Mardani A, Moghadam H (2011). A survey of knowledge production of Iranian researchers on AIDS: evidence from the Web of Science database. JHA, 14:35-46.

IssueVol 45 No 9 (2016) QRcode
SectionReview Article(s)
HIV AIDS Research priority Iran

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How to Cite
DOOSTI-IRANI A, HOLAKOUIE-NAIENI K. Determination the Research Priorities in the Field of HIV/AIDS in Iran: A Systematic Review Article. Iran J Public Health. 2016;45(9):1149-1158.