The Comparison of the Impact of Improving Emergency Care on the Prognosis and Treatment Rate of Elderly Patients in the Emergency Departments: A Meta-Analysis
Abstract
Background: A meta-analysis study was implemented to review the comparison of the impact of improving emergency care on the prognosis and treatment rate of elderly patients in the emergency department who have acute strokes.
Methods: An inclusive literature investigation was completed until April 2025, and 1765 related studies were reviewed. The 12 selected studies encompassed 1300 elderly patients in the emergency department who had acute strokes. The dichotomous or continuous methodologies with a fixed or random model were used to assess the comparison of the impact of improving emergency care on the prognosis and treatment rate of elderly patients in the emergency department who have acute strokes using odds ratios (ORs), mean difference (MD), and 95% confidence intervals (CIs).
Results: First-aid nursing had significantly lower rescue time (MD, -11.16; 95% CI, -15.74- -6.58, P<0.001), fatality rate (OR, 0.26; 95% CI, 0.16-0.43, P<0.001), and disability rate (OR, 0.30; 95% CI, 0.15-0.58, P<0.001) compared to control in elderly patients in the emergency department who have acute strokes.
Conclusion: First-aid nursing had significantly lower rescue time, fatality rate, and disability rate compared to control in elderly patients in the emergency department who have acute strokes. Nevertheless, since most of the studies nominated for evaluation in the meta-analysis had low sample sizes, care must be taken when working with their values.
2. Maleki MS, Mazaheri SA, Hosseini SH, et al (2023). Epidemiology of Traumatic Brain Injury in Iran: A Systematic Review and Meta-Analysis. Iran J Public Health, 52 (9):1818-1831.
3. Saheban Maleki M, Khedri B, Ebrahimpour Roodposhti M, et al (2022). Epidemiology of Traumatic Spinal Cord Injuries in Iran; a Systematic Review and Meta-Analysis. Arch Acad Emerg Med, 10 (1):e80.
4. Soroush S, Arefi MF, Pouya AB, et al (2022). The effects of neck, core, and combined stabilization practices on pain, disability, and improvement of the neck range of motion in elderly with chronic non-specific neck pain. Work, 71 (4):889-900.
5. Azizi A, Veisi FM, Amirian F, et al (2016). Epidemiology of lowers limb fractures in patient of taleghani hospital in Kermanshah in 2014. Res J Med Sci, 10:325-329.
6. Bieth T, Beauvais D, Romeu P, et al (2021). Validation of a new test for early assessment of unilateral neglect in acute stroke: The Rapid Unilateral Neglect Screening (RUNS) test. Ann Phys Rehabil Med, 64 (4):101399.
7. Alameri A, Patel P, Abidali H, et al (2020). Su1450 outcomes of ercp in patients with acute stroke: a national study. Gastrointest Endosc, 91 (6):AB352.
8. Han TS, Sharma P (2020). Response by Han and Sharma to Letter Regarding Article, “Prestroke Disability Predicts Adverse Poststroke Outcome: A Registry-Based Prospective Cohort Study of Acute Stroke”. Stroke, 51 (6):e117-e117.
9. Dwyer M, Peterson GM, Gall S, et al 2020). Health care providers’ perceptions of factors that influence the provision of acute stroke care in urban and rural settings: A qualitative study. SAGE Open Med, 8:2050312120921088.
10. Bruno A, Nichols FT (2020). Letter by Bruno and Nichols Regarding Article, “Prestroke Disability Predicts Adverse Poststroke Outcome: A Registry-Based Prospective Cohort Study of Acute Stroke”. Stroke, 51 (6):e116.
11. Abraira L, Giannini N, Santamarina E, et al (2020). Corrigendum to "Correlation of blood biomarkers with early-onset seizures after an acute stroke event" [Epilepsy Behav 104(Pt B) (2020 Mar)]. Epilepsy Behav, 106:107045.
12. Benfield JK, Everton LF, Bath PM, et al (2020). Accuracy and clinical utility of comprehensive dysphagia screening assessments in acute stroke: A systematic review and meta-analysis. J Clin Nurs, 29 (9-10):1527-1538.
13. Suda S, Muraga K, Ishiwata A, et al (2020). Early Cognitive Assessment Following Acute Stroke: Feasibility and Comparison between Mini-Mental State Examination and Montreal Cognitive Assessment. J Stroke Cerebrovasc Dis, 29 (4):104688.
14. Han JY, Tan IYL (2020). Retrospective single-centre experience on the effect of the DAWN trial on the utilisation pattern, diagnostic yield and accuracy of CT perfusions performed for suspected acute stroke. J Med Imaging Radiat Oncol, 64 (4):477-483.
15. Baby P (2020). Malnutrition in acute stroke: what are we treating? BJNN, 16 (Sup2):S4-S9.
16. Cook AM, Morgan Jones G, Hawryluk GWJ, et al (2020). Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients. Neurocrit Care, 32 (3):647-666.
17. Rudd A, Bladin C, Carli P, et al (2020). Utstein recommendation for emergency stroke care. Int J Stroke, 15 (5):555-564.
18. Amlie-Lefond C, Shaw DWW, Cooper A, et al (2020). Risk of Intracranial Hemorrhage Following Intravenous tPA (Tissue-Type Plasminogen Activator) for Acute Stroke Is Low in Children. Stroke, 51 (2):542-548.
19. Suddick KM, Cross V, Vuoskoski P, et al (2021). Holding space and transitional space: stroke survivors’ lived experience of being on an acute stroke unit. A hermeneutic phenomenological study. Scand J Caring Sci, 35 (1):104-114.
20. Zaheer M, Pechuho SI (2020). The frequency of elevated serum glucose levels in acute stroke patients who are not known to have diabetes at the time of presentation in lady ready hospital Peshawar a cross-sectional study. IJSBAR, 49 (1):196-199.
21. Morello F, Santoro M, Fargion AT, et al (2021). Diagnosis and management of acute aortic syndromes in the emergency department. Intern Emerg Med, 16 (1):171-181.
22. Qi R, Liu H, Liu C, Xu Y, Liu C (2020). Expression and short‑term prognostic value of miR‑126 and miR‑182 in patients with acute stroke. Exp Ther Med, 19 (1):527-534.
23. Stroup DF, Berlin JA, Morton SC, et al (2000). Meta-analysis of observational studies in epidemiology: a proposal for reporting. JAMA, 283 (15):2008-2012.
24. Gu R, Xu G (2024). A meta-analysis looking at the effects of continuous management for complications related to intraoperative pressure wound ulcers in women with breast cancer. Int J Clin Med Res, 2 (4):100-107.
25. Liberati A, Altman DG, Tetzlaff J, et al (2009). The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol, 62 (10):e1-34.
26. Koang Y (2024). A meta-analysis on the use of photobiomodulation to regulate gingival wound healing in addition to periodontal therapies. Int J Clin Med Res, 2 (4):108-117.
27. Gupta S, Rout G, Patel AH, et al (2018). Efficacy of generic oral directly acting agents in patients with hepatitis C virus infection. J Viral Hepat, 25 (7):771-778.
28. Rabie SB, Kang H-C, Choi M, Suk H (2025). Assessing the efficacy of pharmacist-engaged interventions in influencing antibiotic prescribing behavior among general practitioners: meta-analysis. Int J Clin Med Res, 3 (3):52-65.
29. Higgins J, Thomas J, Chandler J, et al (2019). eds. Cochrane Handbook for Systematic Reviews of Interventions. . 2nd ed. ed. Chichester, UK: Wiley & Sons; .
30. Sheikhbahaei S, Trahan TJ, Xiao J, et al (2016). FDG-PET/CT and MRI for evaluation of pathologic response to neoadjuvant chemotherapy in patients with breast cancer: a meta-analysis of diagnostic accuracy studies. Oncologist, 21 (8):931-939.
31. Gupta A, Das A, Majumder K, et al (2018). Obesity is Independently Associated With Increased Risk of Hepatocellular Cancer–related Mortality. Am J Clin Oncol, 41 (9):874-881.
32. Higgins JP, Thompson SG, Deeks JJ, et al (2003). Measuring inconsistency in meta-analyses. BMJ, 327 (7414):557-560.
33. Haixia W (2016). Talking about the application effect of emergency quick nursing process in rescuing patients with acute stroke. A series Contemp Med, 14 (11):46-48.
34. Wei Y (2017). Effect of emergency nursing fast track on treatment time and effect of acute stroke. The latest Medical Information Abstracts in the World, 17 (A4):246.
35. Yan S (2017). Analysis of the application value of emergency quick nursing process in the rescue of patients with acute stroke. TCM, 15 (1):199-200.
36. Yuhui C (2021). Effect of emergency quick nursing process in the treatment of patients with acute stroke. TCM, 19 (33):160-161.
37. Turner AC, Zachrison KS (2021). Utilization of Advanced Imaging for Acute Ischemic Stroke. Circ Cardiovasc Qual Outcomes, 14 (4):e007845.
38. Huishan Y (2021) Effect of emergency nursing green channel on treatment success rate and satisfaction of acute stroke patients. Grass-roots Medical Forum, pp. 3466-3467.
39. Wenjing Y, Youmei R (2021). Effect of optimization of pre-hospital first aid nursing process on first aid efficiency and prognosis of patients with acute stroke. Heilongjiang med, 45 (12):1274-1275.
40. Juan W, Rongzhi T, Tingyi Z (2022). Study on the effect of optimizing emergency nursing process on patients with acute stroke. Psychol monthly, 17 (3):167-169.
41. Li H, Shen Y, Huang X, et al (2023). Application effect of multidisciplinary collaborative nursing process in emergency care of patients with hypertensive cerebral hemorrhage. Eur Rev Med Pharmacol Sci, 27 (7):2745-2750.
42. Deng Y, Song J (2024). Application Effect Evaluation of Optimizing Emergency Nursing Process Before Emergency Coronary Intervention in Patients with AMI and Hypertension. Altern Ther Health Med, 30 (1):339-343.
43. Wang L, Hao X, Zou W, et al (2024). Optimizing the Effects of a Comprehensive Emergency Nursing Model on Rescued Patients with Acute Myocardial Infarction in the Cardiology Department. Altern Ther Health Med, 30(1):339-343.
44. Zhang Z, Gu D, Li S (2024). The Improved Emergency Nursing Procedure and Human-oriented Nursing Care Can Significantly Reduce Hard Feelings of Patients with Acute Myocardial Infarction. Altern Ther Health Med, 30 (12):406-410.
45. Harrington RA (2019). Prehospital Phase of Acute Stroke Care: Guideline and Policy Considerations as Science and Evidence Rapidly Evolve. Stroke, 50 (7):1637-1639.
46. Schlechtriemen T, Becker M, Hoor L (2019). Prähospitalphase der Schlaganfallversorgung. Der Radiologe, 59 (7):596-602.
47. Hosseinighousheh S, Arefi MF, Pouya AB, et al (2021). Health in disasters in Iranian schools: A systematic review. J Educ Health Promot, 10:365.
48. Azadi F, Amjad RN, Marioryad H, et al (2019). Effect of 12-Week Neck, Core, and Combined Stabilization Exercises on the Pain and Disability of Elderly Patients With Chronic Non-specific Neck Pain: A Clinical Trial. Salmand: Iran J Ageing, 13 (5):614-625.
49. Helms J (1978). Zur chirurgischen Anatomie des Felsenbeins. In: Kleinhirnbrückenwinkel-Tumoren: Diagnostik und Therapie. Ed(s), Plester D, Wende S, Nakayama N. Berlin, Heidelberg: Springer Berlin Heidelberg, pp. 3-23.
50. Ng JC, Churojana A, Pongpech S, et al (2019). Current state of acute stroke care in Southeast Asian countries. Interv Neuroradiol, 25 (3):291-296.
51. Amani S, Abbasi Dolatabadi Z, Ilaghinezhad Bardsiri T, et al (2022). Designing and Validation of Self-Assessment Tool of Professional Competency and Its Psychometrics in the Administrators of Preschool Educational Centers. Iran J Public Health, 51 (11):2582-2591.
52. Zaro-Weber O, Fleischer H, Reiblich L, et al (2019). Penumbra detection in acute stroke with perfusion magnetic resonance imaging: Validation with 15O-positron emission tomography. Ann Neurol, 85 (6):875-886.
53. Avasarala J, Wesley K (2018). Optimization of acute stroke care in the emergency department: a call for better utilization of healthcare resources amid growing shortage of neurologists in the United States. CNS Spectr, 23 (4):248-250.
54. Hosseini Foladi S, Poursadeqiyan M, Sheikh Aboumasoudi A (2023). Emergency First Aid Allocation Model in Prehospital Triage in Two-Level Supply Chain Network. Iran J Public Health, 52 (4):868-869.
55. Rinaldo L, Brinjikji W (2019). Response by Rinaldo and Brinjikji to Letter Regarding Article, “Racial and Ethnic Disparities in the Utilization of Thrombectomy for Acute Stroke: Analysis of Data From 2016 to 2018”. Stroke, 50 (11):e340.
56. Bohmann FO, Kurka N, du Mesnil de Rochemont R, et al (2019). Simulation-Based Training of the Rapid Evaluation and Management of Acute Stroke (STREAM)—A Prospective Single-Arm Multicenter Trial. Front Neurol, 10:969.
57. Rehman H, Kalra A, Kochar A, et al (2020). Secondary prevention of cardiovascular diseases in India: Findings from registries and large cohorts. Indian Heart J, 72 (5):337-344.
58. Yokota C, Yamamoto Y, Kamada M, et al (2019). Acute stroke rehabilitation for gait training with cyborg type robot Hybrid Assistive Limb: A pilot study. J Neurol Sci, 404:11-15.
| Files | ||
| Issue | Vol 55 No 1 (2026) | |
| Section | Review Article(s) | |
| DOI | https://doi.org/10.18502/ijph.v55i1.20973 | |
| Keywords | ||
| Elderly Emergency department Acute strokes First-aid nursing | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |



