Original Article

Comparison of some Anthropometric Parameters and Blood Pressure between Adolescents with Down Syndrome and Healthy Ones

Abstract

Background: Most of the people with Down syndrome have short stature compared to general population. There is also a high prevalence of overweight and obesity, mainly in the adolescence and in the adult life. The aim of this study was to compare some anthropometric parameters, heart rate and blood pressure of children with Down syndrome and those with normal development. Down syndrome is among the most commonly classified categories of mental sub normality, with the incidence at birth being around 1: 700 and 1: 750 in live births in most countries worldwide, with the risk of increasing with mother’s age.

Methods: The sample consisted of 82 children, 32 with Down syndrome and 50 healthy children, male, aged 14-15 yr from the population of Kosovo in 2022. There were no health problems present in the healthy children.

Results: About 53% of children with Down syndrome have normal body mass, 15.62% are overweight, and 21.8 are obese. In terms of blood pressure, Down syndrome children have higher systolic pressure (121.94mm/hg), sd ±21.69 than healthy children (111.18mm/hg, sd ±10.88).

Conclusion: Children with Down syndrome had significantly higher body mass index, heart rate, and systolic pressure at rest compared to healthy children. However, after short physical activity, healthy children exhibited greater diastolic pressure than children with Down syndrome.

1. Cuckle HS, Wald NJ, Thompson SG (1987). Estimating a woman's risk of having a pregnancy associated with Down's syn-drome using her age and serum alpha-fetoprotein level. Br J Obstet Gynaecol, 94 (5): 387-402.
2. Lopes Tde S, Ferreira DM, Pereira RA, Veiga GV, Marins VM (2008). Assess-ment of anthropometric indexes of children and adolescents with Down syndrome. J Pediatr (Rio J), 84 (4): 350-356.
3. Björkstén, B, Bäck, O, Hägglöf, B, Tärnvik, A (1979). Immune function in Down’s syn-drome. In: Güttler, F, Seakins, J.W.T, Harkness, R.A (eds) Inborn Errors of Im-munity and Phagocytosis. Spr, Dord.
4. George EK, Mearin ML, Bouquet J, et al (1996). High frequency of celiac disease in Down syndrome. J Pediatr, 128 (4): 555-557.
5. Yahya NHA, Indriyanti R, Hartanto R (2012). Comparison of the head circum-ference measurement between Down syndrome and normal children. Padjad-jaran Journal of Dentistry, 24 (2):100-106.
6. McCoy EE (1992). Growth patterns in Down’s syndrome. Down syndrome: advanc-es in medical care. New York: Wiley-Liss, Inc.
7. Prasher VP (1995). Overweight and obesity amongst Down's syndrome adults. J In-tellect Disabil Res, 39 (Pt 5): 437–441.
8. Cronk C, Crocker AC, Pueschel SM, et al (1988). Growth charts for children with Down syndrome: 1 month to 18 years of age. Pediatrics, 81 (1): 102–110.
9. Aburawi EH, Nagelkerke N, Deeb A, Ab-dulla S, Abdulrazzaq YM (2015). Nation-al growth charts for United Arab Emir-ates children with Down syndrome from birth to 15 years of age. J Epidemi-ol, 25 (1): 20-29.
10. Su X, Lau JTF, Yu CM, et al (2014). Growth charts for Chinese Down syndrome children from birth to 14 years. Arch Dis Child, 99 (9): 824-829.
11. Cremers MJG, Van der Tweel I, Boersma B, Wit JM, Zonderland M (1996). Growth curves of Dutch children with Down's syndrome. J Intellect Disabil Resz, 40 (Pt 5): 412-420.
12. Tüysüz B, Göknar NT, Öztürk B (2012). Growth charts of Turkish children with Down syndrome. Am J Med Genet A, 158 (11): 2656-2664.
13. Myrelid Å, Gustafsson J, Ollars B, Annerén G (2002). Growth charts for Down's syndrome from birth to 18 years of age. Arch Dis Child, 87 (2): 97-103.
14. Styles ME, Cole TJ, Dennis J, Preece MA (2002). New cross-sectional stature, weight, and head circumference refer-ences for Down's syndrome in the UK and Republic of Ireland. Arch Dis Child, 87 (2): 104-108.
15. Morrison RA, McGrath A, Davidson G, Brown JJ, Murray GD, Lever AF (1996). Low blood pressure in Down's syn-drome: a link with Alzheimer's disease?. Hypertension, 28 (4): 569-575.
16. Richards BW, Enver F (1979). J Ment Defic Res, 23 (2): 123-35.
17. Declaration of Helsinki. World Medical Association. Available from: https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/
18. Marfell-Jones MJ, Stewart A, De Ridder J (2012). International Standards for Anthropo-metric Assessment. International Society for the Advancement of Kinanthropometry: Lower Hutt, New Zealand.
19. World Health Organization (2002). Diet, nutrition, and the prevention of chronic diseases: report of a joint WHO/FAO expert consultation (Vol. 916). World Health Organization.
20. Bertapelli F, Machado MR, do Val Roso R, Guerra‐Júnior G (2017). Body mass in-dex reference charts for the individuals with Down syndrome aged 2‐18 years. J Pediatr (Rio J), 93 (1): 94-99.
21. Vicente A, Bravo-González LA, López-Romero A, Muñoz CS, Sánchez-Meca J (2020). Craniofacial morphology in down syndrome: a systematic review and meta-analysis. Sci Rep, 10: 19895.
22. Pastore E, Marino B, Calzolari A, Digilio MC, Giannotti A, Turchetta A (2000). Clinical and cardiorespiratory assess-ment in children with Down syndrome without congenital heart disease. Arch Pediatr Adolesc Med, 154 (4): 408–410.
Files
IssueVol 53 No 3 (2024) QRcode
SectionOriginal Article(s)
DOI https://doi.org/10.18502/ijph.v53i3.15140
Keywords
Healthy adolescents Down syndrome Anthropometry Blood pressure Heart rate

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Shaqiri B, Bahtiri A. Comparison of some Anthropometric Parameters and Blood Pressure between Adolescents with Down Syndrome and Healthy Ones. Iran J Public Health. 2024;53(3):586-591.