The Burden of Premature Mortality in Southern Iran during 2004-2019 Using Standard Expected Years of Life Lost: A Population-Based Study
Abstract
Background: Traditionally, mortality rates are used to estimate public health problems and determine the relative significance of different causes of mortality, but they cannot necessarily determine the burden of premature death. We aimed to investigate the 16-year trend of burden of premature mortality in Southern Iran.
Methods: In this cross-sectional study, all deaths due to various causes of death in Fars Province from the electronic population-based death registration system (EDRS) were obtained. Crude and age-standardized mortality rate, Years of Life Lost (YLL) and YLL rate data were calculated and to examine the trend, joinpoint regression was used.
Results: During the study period, 281,903 deaths occurred, of which, 59.85% (n=168,735) occurred in men. Also, 42.18% of these deaths (n=118,610) occurred due to cardiovascular diseases (CVDs). The total number of YLLs due to premature death was 4,154,828 years. Of these, 2,591,564 years (62.37%) were in men. The highest number of YLL was due to CVDs, external causes of death and cancer. Trend of YLL rate due to premature mortality was decreasing: the annual percent change (APC) was -2.1% (95% CI -2.6 to -1.6, P<0.001) for males, -0.9% (95% CI -1.4 to -0.4, P=0.002) (P=0.002) for females.
Conclusion: Although the trend of premature death has been decreasing during the years of study, but the seven major causes of premature death in 2004 to 2019 were non-communicable diseases, especially ischemic heart diseases, stroke, external cause of morbidity, and cancer. Furthermore, our findings indicate a change in the role of non-communicable diseases in premature mortality in recent years.
2. Tokuç B, Ayhan S, Saraçoğlu GV(2016). The burden of premature mortality in Turkey in 2001 and 2008. Balkan Med J, 33(6):662-667.
3. Baigi V, Nedjat S, Parsaeian M, Mansournia MA, Aliabadi HR, Fotouhi A (2020). Trend and Projection of Premature Mortality in Iran through 2030: A Modeling Study. Arch Iran Med , 23(2):69-74.
4. Rahmanian V, Rahmanian K, Mansoorian E, Jahromi AS, Madani AJ (2017). Years of potential life lost in the south of Iran in 2011 and 2015: A population-based study. Middle East Journal of Family Medicine, 7(10):91.
5. Nalini M, Oranuba E, Poustchi H, et al (2018). Causes of premature death and their associated risk factors in the Golestan Cohort Study, Iran. BMJ Open, 8(7):e021479.
6. Saadat S, Yousefifard M, Asady H, Jafari AM, Fayaz M, Hosseini MJE (2015). The most important causes of death in Iranian population; a retrospective cohort study. Emerg (Tehran), 3(1):16-21.
7. Sheidaei A, Gohari K, Kasaeian A, et al (2017). National and subnational patterns of cause of death in Iran 1990–2015: applied methods. Arch Iran Med, 20(1):2-11.
8. Kazemi E, Khosravi A, Aghamohamadi S, Shariati M, Kazemeini H (2021). Trends in premature mortality in the Islamic Republic of Iran: probability of dying between ages 30 and 70 years. East Mediterr Health J, 27(1):33-40.
9. Mokhtari AM, Sahraian S, Hassanipour S, Baseri A, Mirahmadizadeh AJ (2019). The epidemiology of suicide in the elderly population in Southern Iran, 2011–2016. Asian J Psychiatr, 44:90-94.
10. Izadi N, Mirtorabi SD, Najafi F, Nazparvar B, Kangavari HN, Nazari SS (2018). Trend of years of life lost due to suicide in Iran (2006–2015). Int J Public Health, 63(8):993-1000.
11. Farivarnia F, Entezarmahdi R, Delirrad MJIJoMT, Medicine F (2020). The Epidemiology of Human Mortality in West Azerbaijan Province, Iran, 2016. International Journal of Medical Toxicology and Forensic Medicine, 10(4):30049.
12. Shahraz S, Forouzanfar MH, Sepanlou SG, et al (2014). Population health and burden of disease profile of Iran among 20 countries in the region: from Afghanistan to Qatar and Lebanon. Arch Iran Med, 17(5):336-42.
13. Sankoh O, Sharrow D, Herbst K, et al (2014). The INDEPTH standard population for low-and middle-income countries, 2013. Glob Health Action, 7:23286.
14. Gupta PD (1993). Standardization and decomposition of rates: a user's manual: US Department of Commerce, Economics and Statistics Administration, Bureau of the Census. Current Population Report, pp: 23-186.
15. Li Y, Zeng X, Liu J, et al (2017). Can China achieve a one-third reduction in premature mortality from non-communicable diseases by 2030? BMC Med, 15(1):132.
16. Mathers CD, Vos T, Lopez AD, Salomon J, Ezzati MJGWHO (2001). National burden of disease studies: a practical guide. WHO.
17. Nahvijou AJIJoPH (2021). Disability-Adjusted Life Years (DALY) for Cancers in Iran, 1990 to 2016: Review of Findings from the Global Burden of Disease Study. Iran J Public Health, 50(10):2095-2104.
18. Bazargan-Hejazi S, Ahmadi A, Shirazi A, et al (2018). The burden of road traffic injuries in Iran and 15 surrounding countries: 1990–2016. Arch Iran Med, 21(12):556-565.
19. Shahbazi F, Soori H, Khodakarim S, Ghadirzadeh MR, Hashemi Nazari SSJAoTR (2019). Analysis of mortality rate of road traffic accidents and its trend in 11 years in Iran. Arch Trauma Res, 8(1):17-22.
20. Azadnajafabad S, Mohammadi E, Aminorroaya A, et al (2021). Non-communicable diseases’ risk factors in Iran; a review of the present status and action plans. J Diabetes Metab Disord, 22:1-9.
21. Ghasemian A, Ataie-Jafari A, Khatibzadeh S, et al (2014). National and sub-national burden of chronic diseases attributable to lifestyle risk factors in Iran 1990-2013; study protocol. Arch Iran Med, 17(3):146-58.
22. Yarahmadi S, Etemad K, Hazaveh AM, Azhang NJIjoph (2013). Urbanization and non-communicable risk factors in the capital city of 6 big provinces of Iran. Iran J Public Health, 42(Supple1):113-8.
23. Jamshidbeygi E, Rastad H, Qorbani M, et al (2014). National and sub-national trend and burden of injuries in Iran, 1990-2013: a study protocol. Arch Iran Med, 17(3):138-45.
24. Khosravi Shadmani F, Farzadfar F, Larijani B, Mirzaei M, Haghdoost AAJPo (2019). Trend and projection of mortality rate due to non-communicable diseases in Iran: A modeling study. PLoS One, 14(2):e0211622.
25. Naghavi M, Abolhassani F, Pourmalek F, et al (2009). The burden of disease and injury in Iran 2003. Popul Health Metr, 7:9.
26. Poorolajal J, Zamani R, Mir-Moeini R, et al (2012). Five-year evaluation of chronic diseases in Hamadan, Iran: 2005–2009. Iran J Public Health, 41(3):71-81.
27. Forouzanfar MH, Sepanlou SG, Shahraz S, et al (2014). Evaluating causes of death and morbidity in Iran, global burden of diseases, injuries, and risk factors study 2010. Arch Iran Med, 17(5):304-20.
28. Kumar S, Kumar N, Vivekadhish S, Medicine S (2016). Millennium development goals (MDGS) to sustainable development goals (SDGS): Addressing unfinished agenda and strengthening sustainable development and partnership. Indian J Community Med, 41(1):1-4.
29. Naghavi M, Shahraz S, Sepanlou SG, et al (2014). Health transition in Iran toward chronic diseases based on results of Global Burden of Disease 2010. Arch Iran Med, 17(5):321-35.
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Issue | Vol 52 No 10 (2023) | |
Section | Original Article(s) | |
DOI | https://doi.org/10.18502/ijph.v52i10.13858 | |
Keywords | ||
Years of life lost Premature death Mortality rate Join point regression Iran |
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