Short Communication

Renal Insufficiency According to Time after Cancer Diagnosis: Findings of a Nationwide Cross-Sectional Study

Abstract

Background: Little is known about the relationship between renal insufficiency and time after cancer diagnosis.

Methods: The data of 71,302 individuals (aged 19 to 79 yr) that participated in the 2007–2019 Korean National Health and Nutrition Examination Surveys were subjected to analysis. Renal insufficiency was defined as an estimated glomerular filtration rate of < 60 ml/min/1.73 m2. Odds ratios of renal insufficiency were estimated using multivariate logistic regression models adjusted for potential covariates.

Results: Of the 71,302 study subjects, 3.7% were cancer survivors and 2.2% were long-term (≥ 5 yr) survivors. Renal insufficiency was significantly more prevalent among short-term survivors, but not among long-term survivors, than among subjects without cancer.

Conclusion: A cancer history of ≥ 5 yr is not an independent risk factor of renal insufficiency.

 

1. Shapiro CL (2018). Cancer Survivorship. N Engl J Med, 379(25):2438-2450.
2. Felicetti F, Fortunati N, Brignardello E (2018). Cancer survivors: An expanding population with an increased cardiometabolic risk. Diabetes Res Clin Pract, 143:432-442.
3. Launay-Vacher V (2010). Epidemiology of chronic kidney disease in cancer patients: lessons from the IRMA study group. Semin Nephrol, 30(6):548-556.
4. Chang A, Finelli A, Berns JS, Rosner M (2014). Chronic kidney disease in patients with renal cell carcinoma. Adv Chronic Kidney Dis, 21(1):91-95.
5. Soisson S, Ganz PA, Gaffney D, et al (2018). Long-term, adverse genitourinary outcomes among endometrial cancer survivors in a large, population-based cohort study. Gynecol Oncol, 148(3):499-506.
6. Chang CP, Chen YJ, Blackburn B, et al (2020). Genitourinary disease risks among ovarian cancer survivors in a population-based cohort study. Gynecol Oncol, 157(2):529-535.
7. Nome RV, Smastuen MC, Bjoro T, Kiserud CE, Fossa SD (2020). Longitudinal kidney function outcome in aging testicular cancer survivors. Acta Oncol, 59(4):467-474.
8. Shin HY, Linton JA, Shim JY, Kang HT (2015). Cancer survivors aged 40 years or elder are associated with high risk of chronic kidney disease: the 2010-2012 Korean National Health and Nutrition Examination Survey. Asian Pac J Cancer Prev, 16(4):1355-1360.
9. Kweon S, Kim Y, Jang MJ, et al (2014). Data resource profile: the Korea National Health and Nutrition Examination Survey (KNHANES). Int J Epidemiol, 43(1):69-77.
10. Verbeeck RK, Musuamba FT (2009). Pharmacokinetics and dosage adjustment in patients with renal dysfunction. Eur J Clin Pharmacol, 65(8):757-773.
11. Cosmai L, Porta C, Gallieni M, Perazella MA (2016). Onco-nephrology: a decalogue. Nephrol Dial Transplant, 31(4):515-519.
12. Launay-Vacher V, Janus N, Deray G (2016). Renal insufficiency and cancer treatments. ESMO Open, 1(4):e000091.
13. Bacchetta J, Juillard L, Cochat P, Droz JP (2009). Paraneoplastic glomerular diseases and malignancies. Crit Rev Oncol Hematol, 70(1):39-58.
Files
IssueVol 52 No 3 (2023) QRcode
SectionShort Communication(s)
DOI https://doi.org/10.18502/ijph.v52i3.12148
Keywords
Cancer survivors Long term adverse effects Renal insufficiency

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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Hwang IC, Ahn HY. Renal Insufficiency According to Time after Cancer Diagnosis: Findings of a Nationwide Cross-Sectional Study. Iran J Public Health. 2023;52(3):655-658.