Utilization of Activated Carbon Catalyzed Ozonation (ACCO) for Removal of Ciprofloxacin and Vancomycin from Hospital Wastewater
Abstract
Background: Hospital wastewater is considered by health and environmental researchers due to the presence of various hazardous chemical contaminants such as residual of antibiotics and other drugs. The conventional treatment processes are not able to complete removal of them, and could lead to the entry of these compounds into the environment. Then, we aimed to analyze and evaluate the removal of ciprofloxacin and vancomycin antibiotics from hospital wastewater.
Methods: The effect of antibiotic concentration and reaction time was investigated on the performance of single ozonation (SOZ) and activated carbon catalyzed ozonation (ACCO). In addition, COD and BOD of the effluent, antibiotics degradation kinetics and mathematical modeling were determined. Solid phase extraction columns (SPE) and high-performance liquid chromatography (HPLC) methods were used to extract and measure the intended antibiotics, respectively.
Results: The results of this study showed that degradation of both antibiotics follow pseudo-first order kinetic. SOZ was able to eliminate 6 mg/L of vancomycin and ciprofloxacin within 45 and 65 min, respectively. Due to the synergistic effect of activated carbon on ozonation, ACCO significantly reduced the degradation time to 20 and 25 minutes, respectively. BOD/COD ratio at the outlet of ACCO process increases from 0.2 in raw wastewater to 0.4 in treated wastewater, which could be appropriate for biological treatment.
Conclusion: ACCO could be considered an efficient process for degradation of antibiotics in hospital wastewater.
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13. Márquez G, Rodríguez EM, Beltrán FJ, Ál-varez PM (2014). Solar photocatalytic ozonation of a mixture of pharmaceuti-cal compounds in water. Chemosphere, 113:71-78.
14. Nawrocki J, Kasprzyk-Hordern B (2010). The efficiency and mechanisms of cata-lytic ozonation. Appl Catal B-Environ, 99:27-42.
15. Mousavi SMS, Dehghanzadeh R, Ebrahimi SM (2017). Comparative analysis of ozo-nation (O3) and activated carbon cata-lyzed ozonation (ACCO) for destroying chlorophyll a and reducing dissolved organic carbon from a eutrophic water reservoir. Chem Eng J, 314:396-405.
16. Pourakbar M, Moussavi G, Shekoohiyan S (2016). Homogenous VUV advanced ox-idation process for enhanced degrada-tion and mineralization of antibiotics in contaminated water. Ecotoxicol Environ Saf, 125:72-7.
17. Mehrjouei M, Müller S, Möller D (2015). A review on photocatalytic ozonation used for the treatment of water and wastewater. Chem Eng J, 263:209-219.
18. Oh B-T, Seo Y-S, Sudhakar D, et al (2014). Oxidative degradation of endotoxin by advanced oxidation process (O3/H2O2 & UV/H2O2). J Hazard Mater, 279:105-110.
19. Srithep S, Phattarapattamawong S (2017). Kinetic removal of haloacetonitrile pre-cursors by photo-based advanced oxida-tion processes (UV/H2O2, UV/O3, and UV/H2O2/O3). Chemosphere, 176:25-31.
20. Dehghani Kiadehi A, Ebadi A, Aghaeinejad-Meybodi A (2017). Removal of methyl tert-butyl ether (MTBE) from aqueous medium in the presence of nano-perfluorooctyl alumina (PFOAL): Experimental study of adsorption and catalytic ozonation processes. Sep Purif Technol, 182:238-246.
21. Golet EM, Alder AC, Hartmann A, Ternes TA, Giger W (2001). Trace determina-tion of fluoroquinolone antibacterial agents in urban wastewater by solid-phase extraction and liquid chromatog-raphy with fluorescence detection. Anal Chem, 73:3632-8.
22. Hutinel M, Larsson DGJ, Flach C-F (2022). Antibiotic resistance genes of emerging concern in municipal and hospital wastewater from a major Swedish city. Sci Total Environ, 812: 151433.
23. Eaton AD, Franson MAH, Association APH, et al (2005). Standard Methods for the Examination of Water & Wastewater. ed. American Public Health Association.
24. Dehghanzadeh R, Safavy N, Ghaem Ma-ghami Hezaveh SJ, et al (2014). Deter-mination of Extraction and Analysis Method for Imipenem in Hospital Sew-age Samples Using High Performance Liquid Chromatography-UV Detector and with Solid Phase Extraction Col-umn. Arak Medical University Journal, 17:9-18.
25. Yargeau V, Leclair C (2007). Potential of ozonation for the degradation of anti-biotics in wastewater. Water Sci Technol, 55:321-6.
26. Naddeo V, Ricco D, Scannapieco D, Bel-giorno V (2012). Degradation of Antibi-otics in Wastewater during Sonolysis, Ozonation, and Their Simultaneous Ap-plication: Operating Conditions Effects and Processes Evaluation. Int J Photoener-gy, 2012: 624270.
27. Ahmed MJ, Theydan SK (2014). Fluoro-quinolones antibiotics adsorption onto microporous activated carbon from lig-nocellulosic biomass by microwave py-rolysis. J Taiwan Inst Chem E, 45:219-226.
28. Shokouhi SB, Dehghanzadeh R, Aslani H, Shahmahdi N (2020). Activated carbon catalyzed ozonation (ACCO) of Reac-tive Blue 194 azo dye in aqueous saline solution: Experimental parameters, ki-netic and analysis of activated carbon properties. Journal of Water Process Engineer-ing, 35:101188.
29. Stan M, Lung I, Soran M-L, et al (2017). Removal of antibiotics from aqueous so-lutions by green synthesized magnetite nanoparticles with selected agro-waste extracts. Process Saf Environ, 107:357-372.
2. Madikizela LM, Ncube S, Chimuka L (2020). Analysis, occurrence and removal of pharmaceuticals in African water re-sources: A current status. J Environ Man-age, 253:109741.
3. López-Serna R, Petrović M, Barceló D (2012). Occurrence and distribution of multi-class pharmaceuticals and their ac-tive metabolites and transformation products in the Ebro River basin (NE Spain). Sci Total Environ, 440:280-289.
4. Bueno MJM, Gomez MJ, Herrera S, et al (2012). Occurrence and persistence of organic emerging contaminants and priority pollutants in five sewage treat-ment plants of Spain: Two years pilot survey monitoring. Environ Pollut, 164:267-273.
5. Liu H-Q, Lam JCW, Li W-W, Yu H-Q, Lam PKS (2017). Spatial distribution and re-moval performance of pharmaceuticals in municipal wastewater treatment plants in China. Sci Total Environ, 586:1162-1169.
6. Hollis A, Ahmed Z (2013). Preserving An-tibiotics, Rationally. N Engl J Med, 369:2474-2476.
7. He X, Mezyk SP, Michael I, Fatta-Kassinos D, Dionysiou DD (2014). Degradation kinetics and mechanism of β-lactam an-tibiotics by the activation of H2O2 and Na2S2O8 under UV-254 nm irradiation. J Hazard Mater, 279:375-383.
8. Furia F, Minella M, Gosetti F, Turci F, et al (2021). Elimination from wastewater of antibiotics reserved for hospital settings, with a Fenton process based on zero-valent iron. Chemosphere, 283:131170.
9. Ekwanzala MD, Dewar JB, Kamika I, Momba MNB (2020). Comparative ge-nomics of vancomycin-resistant Entero-coccus spp. revealed common resistome determinants from hospital wastewater to aquatic environments. Sci Total Envi-ron, 719:137275.
10. Babić S, Ćurković L, Ljubas D, Čizmić M (2017). TiO2 assisted photocatalytic deg-radation of macrolide antibiotics. Curr Opin Green Sustain Chem, 6:34-41.
11. Pan M, Chu LM (2017). Fate of antibiotics in soil and their uptake by edible crops. Sci Total Environ, 599–600:500-512.
12. Mir-Tutusaus JA, Parladé E, Llorca M, et al (2017). Pharmaceuticals removal and microbial community assessment in a continuous fungal treatment of non-sterile real hospital wastewater after a coagulation-flocculation pretreatment. Water Res, 116:65-75.
13. Márquez G, Rodríguez EM, Beltrán FJ, Ál-varez PM (2014). Solar photocatalytic ozonation of a mixture of pharmaceuti-cal compounds in water. Chemosphere, 113:71-78.
14. Nawrocki J, Kasprzyk-Hordern B (2010). The efficiency and mechanisms of cata-lytic ozonation. Appl Catal B-Environ, 99:27-42.
15. Mousavi SMS, Dehghanzadeh R, Ebrahimi SM (2017). Comparative analysis of ozo-nation (O3) and activated carbon cata-lyzed ozonation (ACCO) for destroying chlorophyll a and reducing dissolved organic carbon from a eutrophic water reservoir. Chem Eng J, 314:396-405.
16. Pourakbar M, Moussavi G, Shekoohiyan S (2016). Homogenous VUV advanced ox-idation process for enhanced degrada-tion and mineralization of antibiotics in contaminated water. Ecotoxicol Environ Saf, 125:72-7.
17. Mehrjouei M, Müller S, Möller D (2015). A review on photocatalytic ozonation used for the treatment of water and wastewater. Chem Eng J, 263:209-219.
18. Oh B-T, Seo Y-S, Sudhakar D, et al (2014). Oxidative degradation of endotoxin by advanced oxidation process (O3/H2O2 & UV/H2O2). J Hazard Mater, 279:105-110.
19. Srithep S, Phattarapattamawong S (2017). Kinetic removal of haloacetonitrile pre-cursors by photo-based advanced oxida-tion processes (UV/H2O2, UV/O3, and UV/H2O2/O3). Chemosphere, 176:25-31.
20. Dehghani Kiadehi A, Ebadi A, Aghaeinejad-Meybodi A (2017). Removal of methyl tert-butyl ether (MTBE) from aqueous medium in the presence of nano-perfluorooctyl alumina (PFOAL): Experimental study of adsorption and catalytic ozonation processes. Sep Purif Technol, 182:238-246.
21. Golet EM, Alder AC, Hartmann A, Ternes TA, Giger W (2001). Trace determina-tion of fluoroquinolone antibacterial agents in urban wastewater by solid-phase extraction and liquid chromatog-raphy with fluorescence detection. Anal Chem, 73:3632-8.
22. Hutinel M, Larsson DGJ, Flach C-F (2022). Antibiotic resistance genes of emerging concern in municipal and hospital wastewater from a major Swedish city. Sci Total Environ, 812: 151433.
23. Eaton AD, Franson MAH, Association APH, et al (2005). Standard Methods for the Examination of Water & Wastewater. ed. American Public Health Association.
24. Dehghanzadeh R, Safavy N, Ghaem Ma-ghami Hezaveh SJ, et al (2014). Deter-mination of Extraction and Analysis Method for Imipenem in Hospital Sew-age Samples Using High Performance Liquid Chromatography-UV Detector and with Solid Phase Extraction Col-umn. Arak Medical University Journal, 17:9-18.
25. Yargeau V, Leclair C (2007). Potential of ozonation for the degradation of anti-biotics in wastewater. Water Sci Technol, 55:321-6.
26. Naddeo V, Ricco D, Scannapieco D, Bel-giorno V (2012). Degradation of Antibi-otics in Wastewater during Sonolysis, Ozonation, and Their Simultaneous Ap-plication: Operating Conditions Effects and Processes Evaluation. Int J Photoener-gy, 2012: 624270.
27. Ahmed MJ, Theydan SK (2014). Fluoro-quinolones antibiotics adsorption onto microporous activated carbon from lig-nocellulosic biomass by microwave py-rolysis. J Taiwan Inst Chem E, 45:219-226.
28. Shokouhi SB, Dehghanzadeh R, Aslani H, Shahmahdi N (2020). Activated carbon catalyzed ozonation (ACCO) of Reac-tive Blue 194 azo dye in aqueous saline solution: Experimental parameters, ki-netic and analysis of activated carbon properties. Journal of Water Process Engineer-ing, 35:101188.
29. Stan M, Lung I, Soran M-L, et al (2017). Removal of antibiotics from aqueous so-lutions by green synthesized magnetite nanoparticles with selected agro-waste extracts. Process Saf Environ, 107:357-372.
| Files | ||
| Issue | Vol 52 No 7 (2023) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/ijph.v52i7.13255 | |
| Keywords | ||
| Catalyzed ozonation Antibiotic Hospital wastewater Activated carbon | ||
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How to Cite
1.
Ghanbari-Ghozikali M, Mohammadpour A, Dehghanzadeh R. Utilization of Activated Carbon Catalyzed Ozonation (ACCO) for Removal of Ciprofloxacin and Vancomycin from Hospital Wastewater. Iran J Public Health. 2023;52(7):1522-1535.
