Original Article

Mental Health Assessment of Cancer Patients: Prevalence and Predictive Factors of Depression and Anxiety

Abstract

Background: Patients with oncological diseases often have mental disorders in the form of comorbidity. The aim of this study was to research the association of cancer with the presence of symptoms of depression and anxiety in primary health care patients.

Methods: This prospective observational study done in 2020 included adult users of health care at the Health Center Trstenik, Central Serbia, aged 19 and over, both sexes, with a diagnosis of oncological disease. A research instrument to assess depressive symptoms is used PHQ-9 (The Patient Health Questionnaire) questionnaire, derived from PRIME MD- and (The Primary Care Evaluation of Mental Disorders), and the Beck Anxiety Scale (BAI) to register the presence of certain anxiety symptoms.

Results: The largest percentage of patients had symptoms of mild (27.2%) or moderate depression (22%), while 18% reported symptoms of major depression. The level of depression was higher in older subjects, in the presence of chronic diseases with greater limitations of activity and the presence of difficulties in performing daily activities, with a more pronounced effect of pain on activity, the presence of stress. All subjects were characterized as persons with severe anxiety (score 26-63). The level of anxiety was higher in older respondents, in the presence of long-term illness, with greater limitations of activities and difficulties in performing daily activities, with a more pronounced influence of pain on performing activities and the influence of the media.

Conclusion: Caring for the mental health of cancer patients must occupy a significant part of each country's national health policy.

1. Daré LO, Bruand P, Gérard D, et al (2019). Co-morbidities of mental disorders and chronic physical diseases in developing and emerging countries: a meta-analysis. BMC Public Health, 19: 304.
2. Chiu CJ, Hsu YC, Tseng SP (2017). Psychological prognosis after newly diagnosed chronic conditions: Socio-demographic and clinical correlations. Int Psychogeriatr, 29: 281–92.
3. Comijs HC, Nieuwesteeg J, Kok R, et al (2015). The two-year course of late-life depression; results from the Netherlands study of depression in older persons. BMC Psychiatry, 15: 20.
4. Kristina Geue, Philipp Göbel, Katja Leuteritz, et al (2019). Anxiety and Depression in Young Adult German Cancer Patients: Time Course and Associated Factors. Psychooncology, 28 (10): 2083-90.
5. Mitchell AJ, Chan M, Bhatti H, et al (2011). Prevalence of depression, anxiety, and adjustment disorder in oncological, haematological, and palliative-care settings: a meta-analysis of 94 interview-based studies. The Lancet Oncol, 12 (2): 160–74.
6. Lu D, Andersson TM, Fall K, Hultman CM, Czene K, Valdimarsdottir U, Fang F (2016). Clinical Diagnosis of Mental Disorders Immediately Before and After Cancer Diagnosis: A Nationwide Matched Cohort Study in Sweden. JAMA Oncol, 2 (9): 1188–96.
7. Jianwei Zhu, Arvid Sjölander, Katja Fall, Unnur Valdimarsdottir, Fang Fang (2018). Mental disorders around cancer diagnosis and increased hospital admission rate - a nationwide cohort study of Swedish cancer patients. BMC Cancer, 18: 322.
8. Ozaki Y, Sposito AP, Bueno DR, Guariento ME (2015). Depression and chronic diseases in the elderly. Rev Soc Bras Clin Med, 13 (2): 149–53.
9. Granek L, Nakash O, Ariad S, Shapira S, Ben-David M (2019). Strategies and Barriers in Addressing Mental Health and Suicidality in Patients With Cancer. Oncol Nurs Forum, 46 (5): 561-71.
10. Granek L, Nakash O, Ben-David M, Shapira S, Ariad S (2018). Oncologists' Treatment Responses to Mental Health Distress in Their Cancer Patients. Qual Health Res, 28 (11): 1735-45.
11. Vuk Pisk S, Filipčić I, Bogović A, Milovac Ž, Todorić Laidlaw I, Caratan S (2017). Ma-lignant diseases and mental disorders - prevalence, mortality, therapeutic chal-lenge. Soc Psychiatry, 45: 187-201.
12. Eurostat (2013). European Health Interview Survey (EHIS wave 2). Methodological manual, 2013 Edition. Luxembourg: Publications Office of the European Union.
13. Beck AT, Steer RA (1990). Beck Anxiety Inventory (BAI) Manual. Oxford (UK): Pearson.
14. Kroenke K, Spitzer RL, Williams JB (2001). The PHQ-9: Validity of a Brief Depression Severity Measure. J Gen Intern Med, 16 (9): 606-13.
15. Bøen H, Dalgard OS, Bjertness E (2012). The importance of social support in the associations between psychological distress and somatic health problems and socio-economic factors among older adults living at home: a cross sectional study. BMC Geriatr, 12: 27.
16. Yi JC, Syrjala KL (2017). Anxiety and Depression in Cancer Survivors. Med Clin North Am, 101 (6): 1099-113.
17. Vehling S, Mehnert A, Hartmann M, Oing C, Bokemeyer C, Oechsle K (2016). Anxiety and depression in long-term testicular germ cell tumor survivors. Gen Hosp Psychiatry, 38: 21–5.
18. Marroquin B, Czamanski-Cohen J, Weihs KL, Stanton AL (2016). Implicit loneliness, emotion regulation, and depressive symptoms in breast cancer survivors. J Behav Med, 39 (5): 832–44.
19. Cohee AA, Adams RN, Johns SA, B, et al (2017). Long-term fear of recurrence in young breast cancer survivors and partners. Psychooncology, 26 (1): 22-8.
20. Koch L, Bertram H, Eberle A, et al (2014). Fear of recurrence in long-term breast cancer survivors—still an issue. Results on prevalence, determinants, and the association with quality of life and depression from the cancer survivorship—a multi-regional population-based study. Psychooncology, 23: 547–54.
21. Inhestern L, Beierlein V, Bultmann JC, et al (2017). Anxiety and depression in working-age cancer survivors: a register-based study. BMC Cancer. 17 (1): 347.
22. Linden W, Vodermaier A, Mackenzie R, Greig D (2012). Anxiety and depression after cancer diagnosis: prevalence rates by cancer type, gender, and age. J Affect Disord, 141 (2-3): 343-51.
23. Swartzman S, Booth JN, Munro A, Sani F (2017). Posttraumatic stress disorder after cancer diagnosis in adults: A meta-analysis. Depress Anxiety, 34 (4): 327–39.
24. Hinz A, Herzberg PY, Lordick F, et al (2019). Age and gender differences in anxiety and depression in cancer patients compared with the general population. Eur J Cancer Care (Engl), 28 (5): e13129.
25. Braamse AM, van Turenhout ST, Terhaar Sive Droste JS, et al (2016). Factors associated with anxiety and depressive symptoms in colorectal cancer survivors. Eur J Gastroenterol Hepatol, 28 (7): 831–5.
26. Muffly LS, Hlubocky FJ, Khan N, et al (2016). Psychological morbidities in adolescent and young adult blood cancer patients during curative-intent therapy and early survivorship. Cancer, 122 (6): 954–61.
27. Tsaras K, Papathanasiou IV, Mitsi D, et al (2018). Assessment of Depression and Anxiety in Breast Cancer Patients: Prevalence and Associated Factors. Asian Pac J Cancer Prev, 19 (6): 1661-9.
28. Mols F, Schoormans D, de Hingh I, Oerlemans S, Husson O (2018). Symptoms of anxiety and depression among colorectal cancer survivors from the population-based, longitudinal PROFILES Registry: Prevalence, predictors, and impact on quality of life. Cancer, 124 (12): 2621-8.
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IssueVol 50 No 10 (2021) QRcode
SectionOriginal Article(s)
DOI https://doi.org/10.18502/ijph.v50i10.7502
Keywords
Mental health Cancer Patients Depression Anxiety

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How to Cite
1.
Vucic V, Radovanovic S, Radevic S, Savkovic Z, Mihailovic N, Mihaljevic O, Zivanović Macuzic I, Djordjic M, Gavrilovic A, Boskovic Matic T. Mental Health Assessment of Cancer Patients: Prevalence and Predictive Factors of Depression and Anxiety. Iran J Public Health. 2021;50(10):2017-2027.