Analysis of Adverse Reactions of Blood Transfusion and Discussion of Influencing Factors in Linyi Area from 2013 To 2020
Abstract
Background: We aimed to explore the influencing factors of clinical adverse blood transfusion reactions, to provide theoretical basis and support for clinical safe blood transfusion, and to minimize the occurrence of adverse blood transfusion reactions.
Methods: The method was to retrospectively analyze the report of adverse blood transfusion reports from 6 hospitals in Linyi area, Shandong, China to the blood station in Linyi City center from 2013 to 2020. We aimed to classify factors, analyze the occurrence of adverse transfusion reactions, and discuss the correlation between the occurrence of adverse transfusion reactions and the above factors.
Results: Overall, 248 patients (77.98%) had a history of blood transfusion. The difference between this group and the group with no history was statistically significant (P<0.05). The incidence of adverse transfusion reactions in middle-aged and elderly patients was relatively high, especially for those over 50 yr old, with an adverse reaction of 135, for example, the proportion reached 42.45%. In addition, a retrospective analysis found that the occurrence of adverse transfusion reactions was mostly concentrated from Mar to Sep, a total of 228 cases, accounting for 71.69% of all adverse reactions, which was the highest incidence of adverse transfusion reactions.
Conclusion: The main adverse reactions of transfusion were allergic reactions, followed by non-hemolytic febrile reactions, mainly caused by transfusion of suspended red blood cells.
2. Bassi R, Aggarwal S, Bhardwaj K, et al (2017). Patterns of Adverse Transfusion Reactions in a Tertiary Care Centre of North India: A Step Towards Hemovigi-lance. Indian J Hematol Blood Transfus, 33(2):248-253.
3. Philip J, Pawar A, Chatterjee T, et al (2016). Non Infectious Complications Related to Blood Transfusion: An 11 year Retro-spective Analysis in a Tertiary Care Hos-pital. Indian J Hematol Blood Transfus, 32(3): 292-298.
4. Perelman I, Khair S, Dermer E, et al (2019). The epidemiology of multicomponent blood transfusion: a systematic review. Transfus Med, 29(2): 80-94.
5. Kato H, Nakayama T, Uruma M, et al (2015). A retrospective observational study to assess adverse transfusion reac-tions of patients with and without prior transfusion history. Vox Sang, 108(3): 243-250.
6. De Pascale MR, Belsito A, Sommese L, et al (2019). Blood transfusions and adverse acute events: a retrospective study from 214 transfusion-dependent pediatric pa-tients comparing transfused blood com-ponents by apheresis or by whole blood. Ann Ist Super Sanita, 55(4): 351 -356.
7. He C, Deng S (2020). Analysis of 79 cases of adverse reactions caused by blood transfusion and its counter measures. La-boratory Medicine and Clinical, 15(22): 3339-3341.
8. Daurat G (2010). Reporting and notification of transfusion serious adverse events in France. Transfus Clin Biol, 17(5/6): 362-365.
9. Luo B, Li X (2017). Analysis of related fac-tors of transfusion adverse reactions in 15594 blood recipients and preventive measures. Clinical Transfusion and Examina-tion, 2017: 36-39.
10. Goel R, Tobian AAR, Shaz BH (2019). Non-infectious transfusion-associated adverse events and their mitigation strat-egies. Blood, 133(17): 1831-1839.
11. Raval JS, Griggs JR, Fleg A (2020). Blood Product Transfusion in Adults: Indica-tions, Adverse Reactions, and Modifica-tions. Am Fam Physician, 102(1): 30-38.
| Files | ||
| Issue | Vol 50 No 7 (2021) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/ijph.v50i7.6631 | |
| Keywords | ||
| Blood transfusion Allergic reactions Fever Blood products | ||
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