The Association between Suicidal Ideation and Albuminuria in Korean Adults
Abstract
Background: Data on the association between suicide and kidney function in the general population are scarce. This study evaluated albuminuria across suicidal ideation in Korean adults.
Methods: We performed a cross-sectional study using data from the 2011 to 2013 Korean National Health and Nutrition Examination Survey. Overall, 14,101 adults were included in an examination of the amount of albuminuria associated with suicidal ideation. Suicidal ideation was measured using a self-reported questionnaire and albuminuria was assessed using the urinary albumin-to-creatinine ratio (ACR).
Results: Various factors, including suicidal ideation, were associated with ACR. Multivariate regression analyses were stratified by age group and type 2 diabetes due to their strong relation to ACR. In the non-diabetic young group, individuals with suicidal ideation presented ACR 11.4 mg/g higher than those without suicidal ideation (P=0.038).
Conclusion: In healthy young people, suicidal ideation is associated with increased albuminuria.
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2. WHO (2019). The global burden of disease-estimates for 2000-2016. Geneva; World Health Organization.
3. CDC (2015). Suicide facts at a glance 2015. National Center for Injury Prevention and Control.
4. Fazel S, Runeson B (2020). Suicide. N Engl J Med, 382:266-274.
5. Bautovich A, Katz I, Smith M, Loo CK, Harvey SB (2014). Depression and chronic kidney disease: A review for clinicians. Aust N Z J Psychiatry, 48:530-41.
6. Liu CH, Yeh MK, Weng SC, Bai MY, Chang JC (2017). Suicide and chronic kidney disease: a case-control study. Nephrol Dial Transplant, 32:1524-1529.
7. Jhee JH, Lee E, Cha MU, et al (2017). Prevalence of depression and suicidal ideation increases proportionally with renal function decline, beginning from early stages of chronic kidney disease. Medicine (Baltimore), 96:e8476.
8. Liu Q, Li YX, Hu ZH, Jiang XY, Li SJ, Wang XF (2018). Reduced estimated glomerular filtration rate is associated with depressive symptoms in elder Chinese: A population-based cross-sectional study. Neurosci Lett, 666:127-132.
9. Chronic Kidney Disease Prognosis C, Matsushita K, van der Velde M, et al (2010). Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet, 375:2073-81.
10. Katon WJ, Lin EH, Russo J, et al (2004). Cardiac risk factors in patients with diabetes mellitus and major depression. J Gen Intern Med, 19:1192-9.
11. Martens RJH, Kooman JP, Stehouwer CDA, et al (2018). Albuminuria is associated with a higher prevalence of depression in a population-based cohort study: the Maastricht Study. Nephrol Dial Transplant, 33:128-138.
12. Miret M, Ayuso-Mateos JL, Sanchez-Moreno J, Vieta E (2013). Depressive disorders and suicide: Epidemiology, risk factors, and burden. Neurosci Biobehav Rev, 37:2372-4.
13. Kweon S, Kim Y, Jang MJ, et al (2014). Data resource profile: the Korea National Health and Nutrition Examination Survey (KNHANES). Int J Epidemiol, 43:69-77.
14. Gaynes BN, West SL, Ford CA, et al (2004). Screening for suicide risk in adults: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med, 140:822-35.
15. Kim Y, Cho WK (2014). Factors Associated with Successful Smoking Cessation in Korean Adult Males: Findings from a National Survey. Iran J Public Health, 43:1486-96.
16. Gigantesco A, Morosini P (2008). Development, reliability and factor analysis of a self-administered questionnaire which originates from the World Health Organization's Composite International Diagnostic Interview - Short Form (CIDI-SF) for assessing mental disorders. Clin Pract Epidemiol Ment Health, 4:8.
17. Alegria M, NeMoyer A, Falgas Bague I, Wang Y, Alvarez K (2018). Social Determinants of Mental Health: Where We Are and Where We Need to Go. Curr Psychiatry Rep, 20:95.
18. Chrysohoou C, Kollia N, Tousoulis D (2018). The link between depression and atherosclerosis through the pathways of inflammation and endothelium dysfunction. Maturitas, 109:1-5.
19. Tsai YC, Chiu YW, Hung CC, et al (2012). Association of symptoms of depression with progression of CKD. Am J Kidney Dis, 60:54-61.
20. Lambers Heerspink HJ, Brantsma AH, de Zeeuw D, et al (2008). Albuminuria assessed from first-morning-void urine samples versus 24-hour urine collections as a predictor of cardiovascular morbidity and mortality. Am J Epidemiol, 168:897-905.
21. Nock MK, Borges G, Bromet EJ, et al (2008). Suicide and suicidal behavior. Epidemiol Rev, 30:133-54.
22. Turecki G, Brent DA, Gunnell D, et al (2019). Suicide and suicide risk. Nat Rev Dis Primers, 5:74.
2. WHO (2019). The global burden of disease-estimates for 2000-2016. Geneva; World Health Organization.
3. CDC (2015). Suicide facts at a glance 2015. National Center for Injury Prevention and Control.
4. Fazel S, Runeson B (2020). Suicide. N Engl J Med, 382:266-274.
5. Bautovich A, Katz I, Smith M, Loo CK, Harvey SB (2014). Depression and chronic kidney disease: A review for clinicians. Aust N Z J Psychiatry, 48:530-41.
6. Liu CH, Yeh MK, Weng SC, Bai MY, Chang JC (2017). Suicide and chronic kidney disease: a case-control study. Nephrol Dial Transplant, 32:1524-1529.
7. Jhee JH, Lee E, Cha MU, et al (2017). Prevalence of depression and suicidal ideation increases proportionally with renal function decline, beginning from early stages of chronic kidney disease. Medicine (Baltimore), 96:e8476.
8. Liu Q, Li YX, Hu ZH, Jiang XY, Li SJ, Wang XF (2018). Reduced estimated glomerular filtration rate is associated with depressive symptoms in elder Chinese: A population-based cross-sectional study. Neurosci Lett, 666:127-132.
9. Chronic Kidney Disease Prognosis C, Matsushita K, van der Velde M, et al (2010). Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet, 375:2073-81.
10. Katon WJ, Lin EH, Russo J, et al (2004). Cardiac risk factors in patients with diabetes mellitus and major depression. J Gen Intern Med, 19:1192-9.
11. Martens RJH, Kooman JP, Stehouwer CDA, et al (2018). Albuminuria is associated with a higher prevalence of depression in a population-based cohort study: the Maastricht Study. Nephrol Dial Transplant, 33:128-138.
12. Miret M, Ayuso-Mateos JL, Sanchez-Moreno J, Vieta E (2013). Depressive disorders and suicide: Epidemiology, risk factors, and burden. Neurosci Biobehav Rev, 37:2372-4.
13. Kweon S, Kim Y, Jang MJ, et al (2014). Data resource profile: the Korea National Health and Nutrition Examination Survey (KNHANES). Int J Epidemiol, 43:69-77.
14. Gaynes BN, West SL, Ford CA, et al (2004). Screening for suicide risk in adults: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med, 140:822-35.
15. Kim Y, Cho WK (2014). Factors Associated with Successful Smoking Cessation in Korean Adult Males: Findings from a National Survey. Iran J Public Health, 43:1486-96.
16. Gigantesco A, Morosini P (2008). Development, reliability and factor analysis of a self-administered questionnaire which originates from the World Health Organization's Composite International Diagnostic Interview - Short Form (CIDI-SF) for assessing mental disorders. Clin Pract Epidemiol Ment Health, 4:8.
17. Alegria M, NeMoyer A, Falgas Bague I, Wang Y, Alvarez K (2018). Social Determinants of Mental Health: Where We Are and Where We Need to Go. Curr Psychiatry Rep, 20:95.
18. Chrysohoou C, Kollia N, Tousoulis D (2018). The link between depression and atherosclerosis through the pathways of inflammation and endothelium dysfunction. Maturitas, 109:1-5.
19. Tsai YC, Chiu YW, Hung CC, et al (2012). Association of symptoms of depression with progression of CKD. Am J Kidney Dis, 60:54-61.
20. Lambers Heerspink HJ, Brantsma AH, de Zeeuw D, et al (2008). Albuminuria assessed from first-morning-void urine samples versus 24-hour urine collections as a predictor of cardiovascular morbidity and mortality. Am J Epidemiol, 168:897-905.
21. Nock MK, Borges G, Bromet EJ, et al (2008). Suicide and suicidal behavior. Epidemiol Rev, 30:133-54.
22. Turecki G, Brent DA, Gunnell D, et al (2019). Suicide and suicide risk. Nat Rev Dis Primers, 5:74.
| Files | ||
| Issue | Vol 51 No 6 (2022) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/ijph.v51i6.9667 | |
| Keywords | ||
| Albuminuria Kidney function test Suicidal ideation Young adults | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Choi SJ, Nam T, Hwang IC. The Association between Suicidal Ideation and Albuminuria in Korean Adults. Iran J Public Health. 2022;51(6):1245-1250.
