Trends of Colorectal Cancer Incidence, Prevalence and Mortality in Worldwide From 1990 to 2017
Background: Colorectal cancer is a major health problem both in developing and developed countries. This cancer is among the top three commonly diagnosed cancers in males and females. In this context, assessing the Incidence, Prevalence and Mortality Rate trend of this cancer is of great importance.
Methods: We used the data from the GBD 2017 study to assess the global trend of 3 important indicators of colorectal cancer burden and to examine the relationship between trends of these indicators with Human Development Index (HDI). We used the multivariate mixed effects modeling framework with time and HDI as the covariates.
Results: Trend analysis of colorectal cancer burden indicators showed a rather steady trend for mortality rate, while it revealed increasing slopes for both the incidence and prevalence rates. In addition, our findings showed a direct relationship between prevalence and incidence rates of this cancer and HDI level and indirect association between mortality rate and level of HDI.
Conclusion: There were significant changes in indicators of colorectal cancer during the study period. The inverse relationship between mortality due to this cancer and socio-economic status of the countries indicated an urgent need for screening the patients and promoting the level of care in countries with lower levels of HDI.
2. Marley AR, Nan H (2016). Epidemiology of colorectal cancer. Int J Mol Epidemiol Genet, 7(3): 105-114.
3. Valastyan S, Weinberg RA (2011). Tumor metastasis: molecular insights and evolv-ing paradigms. Cell, 147(2): 275-92.
4. Boyle P, Leon ME (2002). Epidemiology of colorectal cancer. Br Med Bull, 64: 1-25.
5. Favoriti P, Carbone G, Greco M, et al (2016). Worldwide burden of colorectal cancer: a review. Updates Surg, 68(1): 7-11.
6. Ansa BE, Coughlin SS, Alema-Mensah E, et al (2018). Evaluation of Colorectal Cancer Incidence Trends in the United States (2000-2014). J Clin Med, 7(2): 22.
7. Haggar FA, Boushey RP (2009). Colorectal cancer epidemiology: incidence, mortality, survival, and risk factors. Clin Colon Rectal Surg, 22(4): 191-7.
8. White A, Ironmonger L, Steele RJC, et al (2018). A review of sex-related differ-ences in colorectal cancer incidence, screening uptake, routes to diagnosis, cancer stage and survival in the UK. BMC Cancer, 18(1): 906.
9. Kim SE, Paik HY, Yoon H, et al (2015). Sex- and gender-specific disparities in colorec-tal cancer risk. World J Gastroenterol, 21(17): 5167-75.
10. Goodarzi E, Beiranvand R, Naemi H, et al (2019). Worldwide incidence and Mortali-ty of colorectal cancer and Human devel-opment index (HDI): an ecological study. World Cancer Res J, 6: e1433.
11. Khazaei S, Rezaeian S, Khazaei S, et al (2016). Effects of Human Development Index and Its Components on Colorectal Cancer Incidence and Mortality: a Global Ecological Study. Asian Pac J Cancer Prev, 17(S3): 253-6.
12. Rafiemanesh H, Mohammadian-Hafshejani A, Ghoncheh M, et al (2016). Incidence and Mortality of Colorectal Cancer and Relationships with the Human Develop-ment Index across the World. Asian Pac J Cancer Prev, 17(5): 2465-73.
13. Shah A, Laird N, Schoenfeld D (1997). A random-effects model for multiple char-acteristics with possibly missing data. J Am Stat Assoc, 92(438):775-9.
14. Fitzmaurice G, Laird N, Ware J (2011). Ap-plied Longitudinal Analysis. 2nd ed. John Wiley & Sons, New York, pp.: 709-710.
15. GBD Collaborators (2018). Findings from the Global Burden of Disease Study 2017. IHME & the Lancet. Available from: https://www.healthdata.org/sites/default/files/files/policy_report/2019/GBD_2017_Booklet.pdf
16. GBD Collaborators (2019). GBD Results Tools. Available from: https://www.healthdata.org/data-visualization/gbd-compare
17. GBD 2017 Mortality Collaborators (2018). Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet, 392(10159): 1684-1735.
18. UNDP (United Nations Development Pro-gramme) (2019). Human Development Report 2019: Beyond income, beyond averages, beyond today: Inequalities in human development in the 21st century. New York.
19. Fitzmaurice G, Laird N, Ware J (2005). Ap-plied Longitudinal Analysis. 1st ed. John Wiley & Sons, New York, pp.: 0-266.
20. Gad AM, El-zayat NI (2018). Fitting Multi-variate Linear Mixed Model for Multiple Outcomes Longitudinal Data with Non-ignorable Dropout. Int J Prob Stat, 7(4): 97-105.
21. Torre LA, Siegel RL, Ward EM, et al (2016). Global Cancer Incidence and Mortality Rates and Trends--An Update. Cancer Ep-idemiol Biomarkers Prev, 25(1): 16-27.
22. Arnold M, Sierra MS, Laversanne M, et al (2017). Global patterns and trends in colorectal cancer incidence and mortality. Gut, 66(4): 683-691.
23. Bray F, Ferlay J, Soerjomataram I, et al (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 68(6): 394-424.
24. Siegel RL, Fedewa SA, Anderson WF, et al (2017). Colorectal Cancer Incidence Pat-terns in the United States, 1974-2013. J Natl Cancer Inst, 109(8): djw322.
25. Oh CM, Won YJ, Jung KW, et al (2016). Community of Population-Based Re-gional Cancer Registries. Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2013. Cancer Res Treat, 48(2): 436-50.
26. Jung KW, Won YJ, Kong HJ, et al (2018). Community of Population-Based Re-gional Cancer Registries. Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2015. Cancer Res Treat, 50(2): 303-316.
27. Vuik FER, Nieuwenburg SAV, Bardou M, et al (2019). Increasing incidence of colorec-tal cancer in young adults in Europe over the last 25 years. Gut BMJ, 68(10): 1820-1826.
|Issue||Vol 52 No 2 (2023)|
|Multivariate mixed effects model Colon and rectum Colorectal Incidence Prevalence Mortality rate|
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