Visualizing the Research Hotspots and Emerging Trends in Neural Tube Defects: A Review
-
Baohong MAO
,
Chichen ZHANG
,
Liping YANG
,
Yanxia WANG
,
Chunhui SU
,
Huining ZHAO
,
Yawen SHAO
,
Qing LIU
Abstract
Background: Neural tube defects (NTDs) are among the second most common serious birth defects and constitute a major cause of infant death. Research about NTDs has achieved tremendous progress over the last 50 years.
Methods: Visualization analysis has been used to explore the hot topic and their emerging trends in NTDs research domain. The scientific literature of research for NTDs has been retrieved from Web of Science™ Core Collection (1966–2014) databases, and final acquire 9125 related bibliographic records, then analyze time trend, distribution of journals, hot keywords, and try to explore the hot topic and their emerging trends in NTDs research domain using Histcite and CiteSpace.
Results: The number of publications about NTDs have shown an increased tendency over the last 50 years although there was on a slight decline. Birth Defects Research Part A published the most articles on NTDs research, followed by Lance and Teratology, and the Lancet had the greatest number of total citations. The largest cited frequency keywords was the “Folate”, followed by “Pregnancy”, “Prevention”, and “Spina bifida”. The research hotspots in NTDs research were homocysteine, anencephaly, and screening.
Conclusion: With the help of visualization analysis, we explore a quantitative and efficient way of understanding the NTDs knowledge field.
1. Yi YN, Lindemann M, Colligs A, Snowball C (2011). Economic burden of neural tube defects and impact of prevention with folic acid: a literature review. Eur J Pediatr, 170(11):1391-400.
2. Yu M, Ping Z, Zhang S, He Y, Dong R, Guo X (2015). The Survey of Birth De-fects Rate Based on Birth Registration System. Chin Med J (Engl), 128(1):7-14.
3. Dai L, Zhu J, Liang J, Wang Y-P, Wang H, Mao M (2011). Birth defects surveillance in China. World J Pediatr, 7(4):302-10.
4. Zaganjor I, Sekkarie A, Tsang BL et al (2016). Describing the Prevalence of Neural Tube Defects Worldwide: A Sys-tematic Literature Review. PLoS One, 11(4):e0151586.
5. De Wals P, Tairou F, Van Allen MI et al (2007). Reduction in neural-tube defects after folic acid fortification in Canada. N Engl J Med, 357(2):135-42.
6. Wallingford JB, Niswander LA, Shaw GM, Finnell RH (2013). The Continuing Chal-lenge of Understanding, Preventing, and Treating Neural Tube Defects. Science, 339(6123): 1222002.
7. Chen CM (2006). CiteSpace II: Detecting and visualizing emerging trends and tran-sient patterns in scientific literature. J Am Soc Inf Sci Tec, 57(3):359-77.
8. Chen C (2013). The Structure and Dynamics of Scientific Knowledge. Mapping Scien-tific Frontiers: The Quest for Knowledge Visualization. London: Springer London; p. 163-99.
9. Chen C (2006). CiteSpace II: Detecting and visualizing emerging trends and transient patterns in scientific literature. J Assoc Soc Inf Sci Tec, 57(3):359-77.
10. Leydesdorff L (1997). Why words and co-words cannot map the development of the sciences. J Am Soc Inf Sci, 48(5):418-27.
11. Chen CM, Ibekwe-SanJuan F, Hou JH (2010). The Structure and Dynamics of Cocitation Clusters: A Multiple-Perspective Cocitation Analysis. J Am Soc Inf Sci Tec, 61(7):1386-409.
12. Mrc vitamin study research group (1991). Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group. Lancet, 338(8760):131-7.
13. Milunsky A, Jick H, Jick SS et al (1989). Mul-tivitamin folic-acid supplementation in early-pregnancy reduces the prevalence of neural-tube defects. JAMA, 262(20):2847-52.
14. Mills JL, Rhoads GG, Simpson JL et al (1989). The absence of a relation between the periconceptional use of vitamins and neural-tube defects. N Engl J Med, 321(7):430-5.
15. Wang CD, Wang Z (1998). Evaluation of the models for Bradford's law. Scientomet-rics, 42(1):89-95.
16. He Q (1999). Knowledge discovery through co-word analysis. Libr Trends, 48(1):133-59.
17. Laurence KM, James N, Miller MH et al (1981). Double-blind randomized con-trolled trial of folate treatment before conception to prevent recurrence of neu-ral-tube defects. Br Med J (Clin Res Ed), 282(6275):1509-11.
18. Czeizel AE, Dudas I (1992). Prevention of the 1st occurrence of neural-tube defects by periconceptional vitamin supplementa-tion. N Engl J Med, 327(26):1832-5.
19. Wald N (1991). Prevention of neural-tube defects - results of the medical-research-council vitamin study. Lancet, 338(8760):131-7.
20. Frosst P, Blom HJ, Milos R et al (1995). A candidate genetic risk factor for vascular-disease - a common mutation in methyl-enetetrahydrofolate reductase. Nat Genet, 10(1):111-3.
21. Vanderput NMJ, Steegerstheunissen RPM, Frosst P et al (1995). Mutated methylene-tetrahydrofolate reductase as a risk factor for spina-bifida. Lancet, 346(8982):1070-1.
22. Berry RJ, Li Z, Erickson JD et al (1999). Prevention of neural-tube defects with folic acid in China. N Engl J Med, 341(20):1485-90.
23. Khoury MJ, Erickson JD, James LM (1982). Etiologic heterogeneity of neural-tube de-fects - clues from epidemiology. Am J Ep-idemiol, 115(4):538-48.
24. Holmes LB, Driscoll SG, Atkins L (1976). Etiologic heterogeneity of neural-tube de-fects. N Engl J Med, 294(7):365-9.
25. Hall JG, Friedman JM, Kenna BA et al (1988). Clinical, genetic, and epidemiolog-ical factors in neural-tube defects. Am J Hum Gene, 43(6):827-37.
26. Hamburger V, Hamilton HL (1951). a series of normal stages in the development of the chick embryo. J Morphol, 88(1):49-92.
27. Karfunkel P (1974). The mechanisms of neural tube formation. Int Rev Cytol, 38(0):245-71.
28. Copp AJ, Greene NDE, Murdoch JN (2003). The genetic basis of mammalian neurulation. Nat Rev Genet, 4(10):784-93.
29. Kibar Z, Vogan KJ, Groulx N et al (2001). Ltap, a mammalian homolog of Dro-sophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. Nat Genet, 28(3):251-5.
30. Juriloff DM, Harris MJ (2000). Mouse mod-els for neural tube closure defects. Hum Mol Genet, 9(6):993-1000.
31. Brock DJH, Sutcliffe RG (1972). Alpha-fetoprotein in antenatal diagnosis of an-encephaly and spina-bifida. Lancet, 2(7770):197-9.
32. Steegers-theunissen RPM, Boers GHJ, Trijbels FJM et al (1994). Maternal hyper-homocysteinemia - a risk factor for neu-ral-tube defects. Metabolism, 43(12):1475-80.
33. Mills JL, McPartlin JM, Kirke PN et al (1995). Homocysteine metabolism in pregnancies complicated by neural-tube defects. Lancet, 345(8943):149-51.
2. Yu M, Ping Z, Zhang S, He Y, Dong R, Guo X (2015). The Survey of Birth De-fects Rate Based on Birth Registration System. Chin Med J (Engl), 128(1):7-14.
3. Dai L, Zhu J, Liang J, Wang Y-P, Wang H, Mao M (2011). Birth defects surveillance in China. World J Pediatr, 7(4):302-10.
4. Zaganjor I, Sekkarie A, Tsang BL et al (2016). Describing the Prevalence of Neural Tube Defects Worldwide: A Sys-tematic Literature Review. PLoS One, 11(4):e0151586.
5. De Wals P, Tairou F, Van Allen MI et al (2007). Reduction in neural-tube defects after folic acid fortification in Canada. N Engl J Med, 357(2):135-42.
6. Wallingford JB, Niswander LA, Shaw GM, Finnell RH (2013). The Continuing Chal-lenge of Understanding, Preventing, and Treating Neural Tube Defects. Science, 339(6123): 1222002.
7. Chen CM (2006). CiteSpace II: Detecting and visualizing emerging trends and tran-sient patterns in scientific literature. J Am Soc Inf Sci Tec, 57(3):359-77.
8. Chen C (2013). The Structure and Dynamics of Scientific Knowledge. Mapping Scien-tific Frontiers: The Quest for Knowledge Visualization. London: Springer London; p. 163-99.
9. Chen C (2006). CiteSpace II: Detecting and visualizing emerging trends and transient patterns in scientific literature. J Assoc Soc Inf Sci Tec, 57(3):359-77.
10. Leydesdorff L (1997). Why words and co-words cannot map the development of the sciences. J Am Soc Inf Sci, 48(5):418-27.
11. Chen CM, Ibekwe-SanJuan F, Hou JH (2010). The Structure and Dynamics of Cocitation Clusters: A Multiple-Perspective Cocitation Analysis. J Am Soc Inf Sci Tec, 61(7):1386-409.
12. Mrc vitamin study research group (1991). Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group. Lancet, 338(8760):131-7.
13. Milunsky A, Jick H, Jick SS et al (1989). Mul-tivitamin folic-acid supplementation in early-pregnancy reduces the prevalence of neural-tube defects. JAMA, 262(20):2847-52.
14. Mills JL, Rhoads GG, Simpson JL et al (1989). The absence of a relation between the periconceptional use of vitamins and neural-tube defects. N Engl J Med, 321(7):430-5.
15. Wang CD, Wang Z (1998). Evaluation of the models for Bradford's law. Scientomet-rics, 42(1):89-95.
16. He Q (1999). Knowledge discovery through co-word analysis. Libr Trends, 48(1):133-59.
17. Laurence KM, James N, Miller MH et al (1981). Double-blind randomized con-trolled trial of folate treatment before conception to prevent recurrence of neu-ral-tube defects. Br Med J (Clin Res Ed), 282(6275):1509-11.
18. Czeizel AE, Dudas I (1992). Prevention of the 1st occurrence of neural-tube defects by periconceptional vitamin supplementa-tion. N Engl J Med, 327(26):1832-5.
19. Wald N (1991). Prevention of neural-tube defects - results of the medical-research-council vitamin study. Lancet, 338(8760):131-7.
20. Frosst P, Blom HJ, Milos R et al (1995). A candidate genetic risk factor for vascular-disease - a common mutation in methyl-enetetrahydrofolate reductase. Nat Genet, 10(1):111-3.
21. Vanderput NMJ, Steegerstheunissen RPM, Frosst P et al (1995). Mutated methylene-tetrahydrofolate reductase as a risk factor for spina-bifida. Lancet, 346(8982):1070-1.
22. Berry RJ, Li Z, Erickson JD et al (1999). Prevention of neural-tube defects with folic acid in China. N Engl J Med, 341(20):1485-90.
23. Khoury MJ, Erickson JD, James LM (1982). Etiologic heterogeneity of neural-tube de-fects - clues from epidemiology. Am J Ep-idemiol, 115(4):538-48.
24. Holmes LB, Driscoll SG, Atkins L (1976). Etiologic heterogeneity of neural-tube de-fects. N Engl J Med, 294(7):365-9.
25. Hall JG, Friedman JM, Kenna BA et al (1988). Clinical, genetic, and epidemiolog-ical factors in neural-tube defects. Am J Hum Gene, 43(6):827-37.
26. Hamburger V, Hamilton HL (1951). a series of normal stages in the development of the chick embryo. J Morphol, 88(1):49-92.
27. Karfunkel P (1974). The mechanisms of neural tube formation. Int Rev Cytol, 38(0):245-71.
28. Copp AJ, Greene NDE, Murdoch JN (2003). The genetic basis of mammalian neurulation. Nat Rev Genet, 4(10):784-93.
29. Kibar Z, Vogan KJ, Groulx N et al (2001). Ltap, a mammalian homolog of Dro-sophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. Nat Genet, 28(3):251-5.
30. Juriloff DM, Harris MJ (2000). Mouse mod-els for neural tube closure defects. Hum Mol Genet, 9(6):993-1000.
31. Brock DJH, Sutcliffe RG (1972). Alpha-fetoprotein in antenatal diagnosis of an-encephaly and spina-bifida. Lancet, 2(7770):197-9.
32. Steegers-theunissen RPM, Boers GHJ, Trijbels FJM et al (1994). Maternal hyper-homocysteinemia - a risk factor for neu-ral-tube defects. Metabolism, 43(12):1475-80.
33. Mills JL, McPartlin JM, Kirke PN et al (1995). Homocysteine metabolism in pregnancies complicated by neural-tube defects. Lancet, 345(8943):149-51.
| Files | ||
| Issue | Vol 49 No 3 (2020) | |
| Section | Review Article(s) | |
| DOI | https://doi.org/10.18502/ijph.v49i3.3122 | |
| Keywords | ||
| Visualization analysis Neural tube defects Scientometrics CiteSpace | ||
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How to Cite
1.
MAO B, ZHANG C, YANG L, WANG Y, SU C, ZHAO H, SHAO Y, LIU Q. Visualizing the Research Hotspots and Emerging Trends in Neural Tube Defects: A Review. Iran J Public Health. 2020;49(3):416-425.
