Original Article

Assessment of Iodine Status in Iranian Students Aged 8-10 Years: Monitoring the National Program for the Prevention and Control of Iodine Deficiency Disorders in 2016

Abstract

Background: Iodine is a key element in the synthesis of thyroid hormones. The deficiency of the secretion of them will Reduce IQ, disturbance in the psychomotor growth and shortened height. Urinary iodine is a good indicator of iodine intake status. Urinary iodine status in at-risk groups is one of the most important indicators of community status.

Methods: All 56 universities/medical faculties in Iran should determine and report median urinary iodine and its relative distribution in school children aged 8 to 10 yr, to determine the status of urine output. The sample size in each university/college is 240 students and the cluster sampling method (48 clusters in each area in 2016) and based on probability Measurement. The amount of urinary iodine was measured quantitatively by acid digestion.

Results: The mean urinary iodine excretion was estimated at 18.61 μg/dl. The median urinary iodine concentration in 52 universities was sufficient, and the national mean of urinary iodine excretion rate was 19.3 μg/dl. The iodine status was estimated in the optimal range in 65.6% of the students and in only 4.7% in the range of moderate and severe deficits, based on the urinary iodine index.

Conclusion: Iodine is sufficient in most parts of the country. The implementation of the country’s national program for the prevention and control of iodine deficiency disorders has made more important the quality control of the collaborative laboratories of this program than before. Moreover, it is absolutely essential to avoid excessive iodine in order to prevent possible side effects.

1. Glinoer D (2006). Iodine nutrition requirements during pregnancy. Thyroid, 16(10):947-8.
2. de Escobar Morreale G (2001).The role of thyroid hormone in fetal neurodevelopment. J Pediatr Endocrinol Metab,14:1453-62.
3. 3. Bleichrodt N, Born MP (1994). A meta-analysis of research on iodine and its relationship to cognitive development. In: The Damaged Brain of Iodine Deficiency: Cognitive, Behavioral, Neuromotor, Educative Aspects. Franklin Institute Symposium Pub. Illustrated, Cognizant Communication Corporation, UC, pp.195-200.
4. De Benoist B, McLean E, Andersson M, Rogers L (2008). Iodine deficiency in 2007: global progress since 2003. Food Nutr Bull., 29(3):195-202.
5. Delange F, de Benoist B, Pretell E, Dunn JT (2001). Iodine deficiency in the world: where do we stand at the turn of the century? Thyroid, 11(5):437-47.
6. Organization WH (2013). Urinary iodine concentrations for determining iodine status in populations. Available from: https://apps.who.int/iris/bitstream/handle/10665/85972/WHO_NMH_NHD_EPG_13.1_eng.pdf?ua=1
7. Azizi F, Delshad H, Amouzegar A et al (2014). Prevention of Iodine-deficiency Induced Goiter and Brain Damage in the Islamic Republic of Iran. IJEM,15(5):411-29.
8. Andersson M, Karumbunathan V, Zimmermann MB (2012). Global Iodine Status in 2011 and Trends over the Past Decade–3. J Nutr, 142(4):744-50.
9. De Benoist B, Andersson M, Egli IM et al (2004). Iodine status worldwide: WHO global database on iodine deficiency. Available from: https://apps.who.int/iris/bitstream/handle/10665/43010/9241592001.pdf
10. Emami A, Shahbazi H, Sabzevari M et al ( 1969). Goiter in Iran. Am J Clin Nutr, 22(12):1584-8.
11. Mirmiran P, Golzarand M, Serra-Majem L, Azizi F (2012). Iron, iodine and vitamin a in the middle East; a systematic review of deficiency and food fortification. Iran J Public Health,41(8):8–19.
12. Azizi F, Kimiagar M, Navai L, Nafarabadi M, Mostafavi H (1986). Goiter in Tehran and suburbs. Recent progress in thyroidology. In Proceedings of the Third Asia and Oceania Thyroid Association Meeting (Vichayanart, A. et al, eds.), Dec 4, pp. 388-391).
13. Kimiagar M, Yassai M, Nafarabadi M, Samimi B, Azizi F (1989). Endemic goiter in boyer-ahmad. MJIRI, 3(1):27-9.
14. Rajabian R, Shahbazi H, Parizadeh J (1990). Goiter survey in Mashhad, Iran. J Mashhad Uni Med Sci, 4:207-10.
15. Azizi F, Sheikholeslam R, Hedayati M et al (2002). Sustainable control of iodine deficiency in Iran: beneficial results of the implementation of the mandatory law on salt iodization. J Endocrinol Invest,25(5):409-13.
16. Azizi F, Mehran L, Sheikholeslam R et al (2008). Sustainability of a well-monitored salt iodization program in Iran: marked reduction in goiter prevalence and eventual normalization of urinary iodine concentrations without alteration in iodine content of salt. J Endocrinol Invest, 31(5):422-31.
17. Delshad H, Amouzegar A, Mirmiran P, Mehran L, Azizi F (2012). Eighteen years of continuously sustained elimination of iodine deficiency in the Islamic Republic of Iran: the vitality of periodic monitoring. Thyroid, 22(4):415-21.
18. Zimmermann MB, Jooste PL, Pandav CS. Iodine-deficiency disorders (2008). The Lancet, 372(9645):1251-62.
19. Jooste PL, Strydom E (2010). Methods for determination of iodine in urine and salt. Best Pract Res Clin Endocrinol Metab, 24(1):77-88.
20. Delshad H, Azizi F (2017). Review of Iodine Nutrition in Iranian Population in the Past Quarter of Century. Int J Endocrinol Metab, 15(4): e57758
21. Kelishadi R, Gheisari A, Zare N et al (2013). Salt intake and the association with blood pressure in young Iranian children: first report from the middle East and north Africa. Int J Prev Med, 4(4):475-83.
Files
IssueVol 49 No 2 (2020) QRcode
SectionOriginal Article(s)
DOI https://doi.org/10.18502/ijph.v49i2.3109
Keywords
Iodine deficiency; Iodized salt; Student Iran

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
REZAIE M, DOLATI S, HARIRI FAR A, ABDOLLAHI Z, SADEGHIAN S. Assessment of Iodine Status in Iranian Students Aged 8-10 Years: Monitoring the National Program for the Prevention and Control of Iodine Deficiency Disorders in 2016. Iran J Public Health. 2020;49(2):377-385.