Original Article

The Pattern of Tuberculosis in Iran: A National Cross-Sectional Study


Background: Despite of the remarkable achievement in control of tuberculosis, it is still a challenging health problem in Iran. Success in any health program depends on monitor the diseases epidemiology and finding the gaps. We aimed to describe the epidemiological profile of TB patients in Iran to find the gaps in the TB program and using the finding to set the program activities.

Methods: This cross-sectional study was performed based on the data of tuberculosis patients registered in Iran in 2016-2017. The information of all TB patients is registered in the TB registry software. The patients were followed during the treatment phase. The data were analyzed by SPSS 23 software using Chi-Square test.

Results:  Overall 12% of cases were Afghans and 72.3% of patients had pulmonary tuberculosis. There was a significant difference in the success rate of treatment in smear-positive pulmonary patients by gender, HIV status, marital status, history of hospitalization and incarceration (P <0.01). The highest prevalence of antibiotic resistance was related to isoniazid (9.9%). In close contact persons who requiring prophylaxis, 65.3% of adults and 73.6% of children received full period of prophylaxis,

Conclusion: Despite of the TB treatment success and low prevalence of MDR cases, TB incidence has not been decreased significantly in Iran. Delay in diagnosis, high TB burden in refugees and close contact investigation and prophylaxis are important issues in the TB control program in Iran to be considered in the control planning.  


1. Fukunaga R, Glaziou P, Harris JB, Date A, Floyd K, Kasaeva T (2021). Epidemiology of tuberculosis and progress toward meeting global targets—worldwide, 2019. MMWR Morb Mortal Wkly Rep, 70 (12): 427.
2. Houben RM, Dodd PJ (2016). The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling. PLoS Med, 13:e1002152.
3. Nyoko YO, Putra IA, Sawitri AA (2014). Correlation Between Demographics, Clinical and Risk Factor for HIV Infection with HIV/TB Coinfected in Amertha Clinic Kerti Praja Foundation Denpasar. Public Health and Preventive Medicine Archive, 2:164677.
4. Nasehi M, Hassanzadeh J, Rezaianzadeh A, Zeigami B, Tabatabaee H, Ghaderi E (2012). Diagnosis delay in smear positive tuberculosis patients. J Res Med Sci, 17:1001-4.
5. Uplekar M, Weil D, Lonnroth K, et al (2015). WHO's new end TB strategy. Lancet, 385:1799-1801.
6. Ministry of Health and Medical Education (2017). Department of Tuberculosis and Leprosy-Annual Report on Tuberculosi in Iran.
7. Janati A, Hosseiny M, Gouya MM, Moradi G, Ghaderi E (2015). Communicable Disease Reporting Systems in the World: A Systematic Review Article. Iran J Public Health, 44:1453-65.
8. Balkhy HH, El Beltagy K, El-Saed A, et al (2017). Prevalence of latent Mycobacterium tuberculosis infection (LTBI) in Saudi Arabia; population based survey. Int J Infect Dis, 60:11-16.
9. Dodd PJ, Looker C, Plumb ID, et al (2016). Age-and sex-specific social contact patterns and incidence of Mycobacterium tuberculosis infection. Am J Epidemiol, 183:156-166.
10. Van Ness SE, Chandra A, Sarkar S, et al (2017). Predictors of delayed care seeking for tuberculosis in southern India: an observational study. BMC Infect Dis, 17:1-9.
11. Hassanzadeh J, Nasehi M, Rezaianzadeh A, Tabatabaee H, Rajaeifard A, Ghaderi E (2013). Pattern of reported tuberculosis cases in Iran 2009–2010. Iran J Public Health, 42:72-78.
12. Khazaei S, Hassanzadeh J, Rezaeian S, et al (2016). Treatment outcome of new smear positive pulmonary tuberculosis patients in Hamadan, Iran: A registry-based cross-sectional study. Egyptian Journal of Chest Diseases and Tuberculosis, 65:825-830.
13. Tesfaye B, Alebel A, Gebrie A, Zegeye A, Tesema C, Kassie B (2018). The twin epidemics: Prevalence of TB/HIV co-infection and its associated factors in Ethiopia; A systematic review and meta-analysis. PloS One, 13:e0203986.
14. Yen YF, Chuang PH, Yen MY, et al (2016). Association of body mass index with tuberculosis mortality: a population-based follow-up study. Medicine (Baltimore), 95(1):e2300.
15. Lin HP, Deng CY, Chou P (2009). Diagnosis and treatment delay among pulmonary tuberculosis patients identified using the Taiwan reporting enquiry system, 2002–2006. BMC Public Health, 9: 1-6.
IssueVol 52 No 1 (2023) QRcode
SectionOriginal Article(s)
DOI https://doi.org/10.18502/ijph.v52i1.11682
Tuberculosis Cross-sectional study Public health Epidemiology Iran

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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Doosti A, Nasehi M, Moradi G, Roshani D, Sharafi S, Ghaderi E. The Pattern of Tuberculosis in Iran: A National Cross-Sectional Study. Iran J Public Health. 2023;52(1):193-200.