STUDY OF MULTI-DRUG RESISTANT SALMONELLA TYPHI IN PATIENTS WITH TYPHOID FEVER

Abstract

Determination of drug resistance rate, as a new major problem in patients with typhoid fever is inevitable for treatment of the disease. In a cross-sectional study, during March 1994 till February 1995, a total of 39 Patients with typhoid fever admitted to dept. of infections diseases, Emam Khomeini Hospital, and were examined for the rate of resistance to routine drugs usually used for treatment of the disease. The results of the present investigation showed that 33% of the patients were resistant to chloramphenicol, 48% to cotrimoxazole, 38% to ampicillin and finally 33% to the triple drug treatment.