Preliminary Report: EVIDENCE OF AUTOSOMAL RECESSIVE FORM OF ALPORT SYNDROME IN IRAN

Abstract

Alport syndrome is a progressive hereditary nephritis leading to renal failure. Nearly all of the documents declare that Alport syndrome is inherited as X-linked dominant trait and reports of autosomal inheritance form is very rare. This paper presents an Iranian large Alport family with autosomal recessive inheritance. In our patients Alport disease was confirmed with electron microscopic studies of renal biopsies.