Evaluation of Nutritional Status of Colorectal Cancer Patients from Algerian East Using Anthropometric Measurements and Laboratory Assessment
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Abstract
Background: Chemotherapy may lead to cancer patient malnutrition, associated with reduced response, and increased complications to anticancer therapy. This study aimed to evaluate the nutritional status of Algerian colorectal cancer patients.
Methods: This cross-sectional study was conducted during 2016-2017 at the Oncology departments from the Algerian East included 90 patients with colorectal cancer. For each patient, a questionnaire, anthropometric measurements and biochemical tests have been done.
Results: The 50-59 yr and 60-69 age groups represented more than half of the population. Obesity and underweight were significantly higher in female patients according to their actual Body mass index (BMI). Prevalence of underweight increased after cancer diagnosis, while obesity prevalence has decreased significantly. The malnutrition classification based on Mid-upper-arm muscle circumference (MUAMC) and the triceps skinfold thickness (TST) has shown a significant higher prevalence of malnutrition among male patients than females. The classification of Nutrition risk index (NRI) has shown a significant high percentage of male patients having malnutrition. In our study, no significant differences were recorded for biochemical tests. Anemia recorded the higher prevalences for both sex compared to other deficiency. Hypoironemia prevalence’s was higher among male patients than females while hypokalemia and hypoproteinemia prevalence’s were higher in female patients.
Conclusion: Malnutrition in CRC patients must be combated by early detection to decrease complications associated to cancer and chemotherapy.
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7. Lopes JP, de Castro Cardoso Pereira PM, dos Reis Baltazar Vicente AF, et al (2013). Nutritional status assessment in colorectal cancer patients. Nutr Hosp, 28(2):412-8.
8. Muscaritoli M, Lucia S, Farcomeni A, et al (2017). Prevalence of malnutrition in pa-tients at first medical oncology visit: the PreMiO study. Oncotarget, 8(45): 79884-79896.
9. Aaldriks AA, van der Geest LG, Giltay EJ, et al (2013). Frailty and malnutrition pre-dictive of mortality risk in older patients with advanced colorectal cancer receiving chemotherapy. J Geriatr Oncol, 4(3):218-26.
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11. Warr DG, Grunberg SM, Gralla RJ, et al (2005). The oral NK(1) antagonist aprepi-tant for the prevention of acute and de-layed chemotherapy-induced nausea and vomiting: Pooled data from 2 random-ised, double-blind, placebo controlled tri-als. Eur J Cancer, 41(9):1278-85.
12. Hong JH, Omur- Ozbek P, Stanek BT, et al (2009). Taste and odorabnormalities in cancer patients. J Support Oncol, 7:58-65.
13. Arnold M, Freisling H, Stolzenberg-Solomon R, et al (2016). Overweight du-ration in older adults and cancer risk: a study of cohorts in Europe and the Unit-ed States. Eur J Epidemiol, 31(9): 893-904.
14. Boyle T, Fritschi L, Platell C, et al (2013).Lifestyle factors associated with survival after colorectal cancer diagnosis. Br J Cancer, 109(3):814-822.
15. De Ulibarri Pérez JI, Picón César MJ, García Benavent E, et al (2002). [Early detection and control of hospital malnutrition]. Nutr Hosp, 17(3):139-46.[Article in Span-ish].
16. Hébuterne X (2009). Dénutrition et traite-ment en cancérologie digestive. http://www.fmcgastro.org/wp-content/uploads/file/pdf/344.pdf
17. Ferrera L.A (2005). Body Mass Index. Nova Publishers.
18. Piquet MA, Hébuterne X (2007). Nutrition en pathologie digestive. Doin Editeurs, John Libbey Eurotext.
19. Lippincott Williams & Wilkins (2008). Manu-al of Nutritional Therapeutics. Wolters Kluwer Health,105-106.
20. Université Médicale Virtuelle Francophone (2011). Diagnostic de la dénutrition et de ses facteurs de risque. http://campus.cerimes.fr/nutrition/enseignement/nutrition_31/site/html/3.html
21. Berg DT (2001). Contemporary Issues in Colorectal Cancer: A Nursing Perspec-tive. Jones & Bartlett Publishers.
22. Negrichi S, Taleb S (2018). Epidemiology of cancers and Prevalence of colorectal can-cer between 2014 and 2016 in the East of Algeria. Transylvanian Review, 26(34):8929-8939.
23. Winkels RM, Snetselaar T, Adriaans A, et al (2016). Changes in body weight in pa-tients with colorectal cancer treated with surgery and adjuvant chemotherapy: An observational study. Cancer Treatment and Research Communications, (9): 111-115
24. Tolentino R, Quizon O (2007). Nutritional status of patients with malignancy of the gastrointestinal tract and other malignan-cies-comparison of chara-cteristics and pattern: two-year study in a private tertiary care hospital in the Philippines. Philip J Oncology, 8:37-44.
25. Blaak E (2001). Gender differences in fat metabolism. Curr Opin Clin Nutr Metab Care, 4(6):499-502.
26. Selvaraj K, Jayalakshmy R, Yousuf A, et al (2017). Can mid-upper arm circumfer-ence and calf circumference be the proxy measures to detect undernutrition among elderly? Findings of a community-based survey in rural Puducherry, India. J Family Med Prim Care, 6(2): 356-359.
27. Righini CA, Timi N, Junet P, et al (2013). Assessment of nutritional status at the time of diagnosis in patients treated for head and neck cancer. Eur Ann Otorhino-laryngol Head Neck Dis, 130(1):8-14.
28. Myers CE, Hoelzinger DB, Truong TN, et al (2017). Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet. Oncotarget, 8(3): 5426-5438.
29. Ziętarska M, Krawczyk-Lipiec J, Kraj L, et al (2017). Nutritional status assessment in colorectal cancer patients qualified to sys-temic treatment. Contemp Oncol (Pozn), 21(2): 157–161.
30. Mahon SM, Casperson DS (1993). Patho-physiology of hypokalemia in patients with cancer: implications for nurses. Oncol Nurs Forum, 20(6):937-46; quiz 947-8.
31. Chen Y, Liu BL, Shang B, et al (2011). Nu-trition support in surgical patients with colorectal cancer. World J Gastroenterol, 17(13): 1779-1786.
32. Thean K, Yo SL, Nambiar R, et al (1988). The use of serum transferrin in the evalu-ation of protein-calorie malnutrition in cancer patients. Ann Acad Med Singapore, 17(1):124-8.
33. Ludwig H, Müldür E, Endler G, et al (2013).Prevalence of iron deficiency across different tumors and its associa-tion with poor performance status, dis-ease status and anemia. Ann Oncol, 24(7):1886-1892.
34. Zietarska M, Krawczyk-Lipiec J, Kraj L et al (2017). Chemotherapy-Related Toxicity, Nutritional Status and Quality of Life in Precachectic Oncologic Patients with, or without, High Protein Nutritional Sup-port. A Prospective, Randomized Study. Nutrients, 9(10): 1108.
35. Kishida T, Shinozawa I, Tanaka S et al (1997). Significance of serum iron and ferritin in patients with colorectal adeno-mas. Scand J Gastroenterol, 32(3):233-7.
36. Naoum FA (2016). Iron deficiency in cancer patients. Rev Bras Hematol Hemoter, 38(4): 325-330.
37. Ludwig H, Van Belle S, Barrett-Lee P, et al (2004). The European Cancer Anaemia Survey (ECAS): a large, multinational, prospective survey defining the preva-lence, incidence, and treatment of anae-mia in cancer patients. Eur J Cancer, 40(15):2293-2306.
38. Bermejo F, García-López S (2009). A guide to diagnosis of iron deficiency and iron deficiency anemia in digestive diseases. World J Gastroenterol, 15(37): 4638-4643.
39. Ludwig H, Evstatiev R, Kornek G, et al (2015). Iron metabolism and iron sup-plementation in cancer patients. Wien Klin Wochenschr, 127(23-24):907-19.
40. Hu WH, Chen HH, Lee KC et al (2016). As-sessment of the Addition of Hypoalbu-minemia to ACS-NSQIP Surgical Risk Calculator in Colorectal Cancer. Medicine (Baltimore), 95(10): e2999.
41. McMillan DC (2009). Systemic inflamma-tion, nutritional status and survival in pa-tients with cancer. Curr Opin Clin Nutr Metab Care, 12(3):223-6.
42. Detsky AS, Baker JP, Mendelson RA, et al (1984). Evaluating the accuracy of nutri-tional assessment techniques applied to hospitalized patients: methodology and comparisons. JPEN J Parenter Enteral Nutr, 8(2):153-9.
43. Barber MD, Ross JA, Fearon KC (1999). Changes in nutritional, functional, and in-flammatory markers in advanced pancre-atic cancer. Nutr Cancer, 35(2):106-10.
44. Forse RA, Rompre C, Crosilla P, et al (1985). Reliability of the total lymphocyte count as a parameter of nutrition. Can J Surg, 28(3):216-9.
2. Hamdi Cherif M, Bidoli E, Birri S, et al (2015). Cancer estimation of incidence and survival in Algeria 2014. J Cancer Res Ther, 3(9):100-4.
3. American Cancer Society (2017). Colorectal Cancer Facts & Figures 2017-2019. Atlan-ta: American Cancer Society.
4. Vrieling A, Kampman E (2010). The role of body mass index, physical activity,and di-et in colorectal cancer recurrence and sur-vival: a review of the literature. Am J Clin Nutr, 92(3):471-490.
5. Ryan AM, Power DG, Daly L, et al (2016). Cancer-associated malnutrition, cachexia and sarcopenia: the skeleton in the hospi-tal closet 40 years later. Proc Nutr Soc, 75(2):199-211
6. Kumar NB (2012). Nutritional Management of Cancer Treatment Effects. Springer Science & Business Media.
7. Lopes JP, de Castro Cardoso Pereira PM, dos Reis Baltazar Vicente AF, et al (2013). Nutritional status assessment in colorectal cancer patients. Nutr Hosp, 28(2):412-8.
8. Muscaritoli M, Lucia S, Farcomeni A, et al (2017). Prevalence of malnutrition in pa-tients at first medical oncology visit: the PreMiO study. Oncotarget, 8(45): 79884-79896.
9. Aaldriks AA, van der Geest LG, Giltay EJ, et al (2013). Frailty and malnutrition pre-dictive of mortality risk in older patients with advanced colorectal cancer receiving chemotherapy. J Geriatr Oncol, 4(3):218-26.
10. Baba AI, Câtoi C (2007). Comparative On-cology: Chapter 19: PRINCIPLES OF ANTICANCER THERAPY, Bucharest: The Publishing House of the Romanian Academy. https://www.ncbi.nlm.nih.gov/books/NBK9546/
11. Warr DG, Grunberg SM, Gralla RJ, et al (2005). The oral NK(1) antagonist aprepi-tant for the prevention of acute and de-layed chemotherapy-induced nausea and vomiting: Pooled data from 2 random-ised, double-blind, placebo controlled tri-als. Eur J Cancer, 41(9):1278-85.
12. Hong JH, Omur- Ozbek P, Stanek BT, et al (2009). Taste and odorabnormalities in cancer patients. J Support Oncol, 7:58-65.
13. Arnold M, Freisling H, Stolzenberg-Solomon R, et al (2016). Overweight du-ration in older adults and cancer risk: a study of cohorts in Europe and the Unit-ed States. Eur J Epidemiol, 31(9): 893-904.
14. Boyle T, Fritschi L, Platell C, et al (2013).Lifestyle factors associated with survival after colorectal cancer diagnosis. Br J Cancer, 109(3):814-822.
15. De Ulibarri Pérez JI, Picón César MJ, García Benavent E, et al (2002). [Early detection and control of hospital malnutrition]. Nutr Hosp, 17(3):139-46.[Article in Span-ish].
16. Hébuterne X (2009). Dénutrition et traite-ment en cancérologie digestive. http://www.fmcgastro.org/wp-content/uploads/file/pdf/344.pdf
17. Ferrera L.A (2005). Body Mass Index. Nova Publishers.
18. Piquet MA, Hébuterne X (2007). Nutrition en pathologie digestive. Doin Editeurs, John Libbey Eurotext.
19. Lippincott Williams & Wilkins (2008). Manu-al of Nutritional Therapeutics. Wolters Kluwer Health,105-106.
20. Université Médicale Virtuelle Francophone (2011). Diagnostic de la dénutrition et de ses facteurs de risque. http://campus.cerimes.fr/nutrition/enseignement/nutrition_31/site/html/3.html
21. Berg DT (2001). Contemporary Issues in Colorectal Cancer: A Nursing Perspec-tive. Jones & Bartlett Publishers.
22. Negrichi S, Taleb S (2018). Epidemiology of cancers and Prevalence of colorectal can-cer between 2014 and 2016 in the East of Algeria. Transylvanian Review, 26(34):8929-8939.
23. Winkels RM, Snetselaar T, Adriaans A, et al (2016). Changes in body weight in pa-tients with colorectal cancer treated with surgery and adjuvant chemotherapy: An observational study. Cancer Treatment and Research Communications, (9): 111-115
24. Tolentino R, Quizon O (2007). Nutritional status of patients with malignancy of the gastrointestinal tract and other malignan-cies-comparison of chara-cteristics and pattern: two-year study in a private tertiary care hospital in the Philippines. Philip J Oncology, 8:37-44.
25. Blaak E (2001). Gender differences in fat metabolism. Curr Opin Clin Nutr Metab Care, 4(6):499-502.
26. Selvaraj K, Jayalakshmy R, Yousuf A, et al (2017). Can mid-upper arm circumfer-ence and calf circumference be the proxy measures to detect undernutrition among elderly? Findings of a community-based survey in rural Puducherry, India. J Family Med Prim Care, 6(2): 356-359.
27. Righini CA, Timi N, Junet P, et al (2013). Assessment of nutritional status at the time of diagnosis in patients treated for head and neck cancer. Eur Ann Otorhino-laryngol Head Neck Dis, 130(1):8-14.
28. Myers CE, Hoelzinger DB, Truong TN, et al (2017). Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet. Oncotarget, 8(3): 5426-5438.
29. Ziętarska M, Krawczyk-Lipiec J, Kraj L, et al (2017). Nutritional status assessment in colorectal cancer patients qualified to sys-temic treatment. Contemp Oncol (Pozn), 21(2): 157–161.
30. Mahon SM, Casperson DS (1993). Patho-physiology of hypokalemia in patients with cancer: implications for nurses. Oncol Nurs Forum, 20(6):937-46; quiz 947-8.
31. Chen Y, Liu BL, Shang B, et al (2011). Nu-trition support in surgical patients with colorectal cancer. World J Gastroenterol, 17(13): 1779-1786.
32. Thean K, Yo SL, Nambiar R, et al (1988). The use of serum transferrin in the evalu-ation of protein-calorie malnutrition in cancer patients. Ann Acad Med Singapore, 17(1):124-8.
33. Ludwig H, Müldür E, Endler G, et al (2013).Prevalence of iron deficiency across different tumors and its associa-tion with poor performance status, dis-ease status and anemia. Ann Oncol, 24(7):1886-1892.
34. Zietarska M, Krawczyk-Lipiec J, Kraj L et al (2017). Chemotherapy-Related Toxicity, Nutritional Status and Quality of Life in Precachectic Oncologic Patients with, or without, High Protein Nutritional Sup-port. A Prospective, Randomized Study. Nutrients, 9(10): 1108.
35. Kishida T, Shinozawa I, Tanaka S et al (1997). Significance of serum iron and ferritin in patients with colorectal adeno-mas. Scand J Gastroenterol, 32(3):233-7.
36. Naoum FA (2016). Iron deficiency in cancer patients. Rev Bras Hematol Hemoter, 38(4): 325-330.
37. Ludwig H, Van Belle S, Barrett-Lee P, et al (2004). The European Cancer Anaemia Survey (ECAS): a large, multinational, prospective survey defining the preva-lence, incidence, and treatment of anae-mia in cancer patients. Eur J Cancer, 40(15):2293-2306.
38. Bermejo F, García-López S (2009). A guide to diagnosis of iron deficiency and iron deficiency anemia in digestive diseases. World J Gastroenterol, 15(37): 4638-4643.
39. Ludwig H, Evstatiev R, Kornek G, et al (2015). Iron metabolism and iron sup-plementation in cancer patients. Wien Klin Wochenschr, 127(23-24):907-19.
40. Hu WH, Chen HH, Lee KC et al (2016). As-sessment of the Addition of Hypoalbu-minemia to ACS-NSQIP Surgical Risk Calculator in Colorectal Cancer. Medicine (Baltimore), 95(10): e2999.
41. McMillan DC (2009). Systemic inflamma-tion, nutritional status and survival in pa-tients with cancer. Curr Opin Clin Nutr Metab Care, 12(3):223-6.
42. Detsky AS, Baker JP, Mendelson RA, et al (1984). Evaluating the accuracy of nutri-tional assessment techniques applied to hospitalized patients: methodology and comparisons. JPEN J Parenter Enteral Nutr, 8(2):153-9.
43. Barber MD, Ross JA, Fearon KC (1999). Changes in nutritional, functional, and in-flammatory markers in advanced pancre-atic cancer. Nutr Cancer, 35(2):106-10.
44. Forse RA, Rompre C, Crosilla P, et al (1985). Reliability of the total lymphocyte count as a parameter of nutrition. Can J Surg, 28(3):216-9.
| Files | ||
| Issue | Vol 49 No 7 (2020) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/ijph.v49i7.3577 | |
| PMCID | PMC7548495 | |
| PMID | 33083290 | |
| Keywords | ||
| Malnutrition; Nutritional deficiencies; Colorectal cancer; Algerian East | ||
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How to Cite
1.
NEGRICHI S, TALEB S. Evaluation of Nutritional Status of Colorectal Cancer Patients from Algerian East Using Anthropometric Measurements and Laboratory Assessment. Iran J Public Health. 2020;49(7):1242-1251.
