THE BACTERICIDAL EFFECTS OF SOME CHEMICAL COMPOUNDS ON ENTEROPATHOGENIC BACTERIA

Abstract

The evaluation of bactericidal effects of chemical compounds is one of the primary duties of the Public health laboratories. To meet this, several compounds were tested against various strains of bacteria (Salmonella typhosa, Sh. flexneri type 2, E. Coli Pathogen serotype 0124B17, and Cholera vibrio-Eltor serotype Inaba) at Reference laboratories, Ministry of Health. It was found that Sodium p-toluensulfonchloramide, Benzalkonium chloride land Calcium hypochlorite at 1000 PPM concentration and in 10 minutes have a complete kil1ing effect on four bacteria and are successively the compound of choice. Sublimate soap and Potassium permanganate in 1/100 concentration have significant killing effects on all tested bacteria in 5 minutes exposure; but at this concentration, both compounds (particularly the second ,one) will deteriorate the exposed materials. Domestic detergents (in ordinary concentrations) and Sodium chloride (even in saturated concentration) have no significant bactericidal effects.