Daily Weather Conditions and Anticipated Death from Cancer
Background: The effect of weather conditions on human health has been documented. However, the role of daily weather on anticipated death remains unclear. This study aimed to evaluate the relationship between daily weather conditions and death in terminally ill cancer patients.
Methods: We retrospectively searched a medical database of 935 consecutive terminally ill cancer patients who passed away in the palliative care unit from Oct 2009 to Sep 2013. We used Poisson regression to assess the relative risk (RR) of anticipated death based on various weather variables, using mean values calculated from the 10 d around the time of death.
Results: The final study population consisted of 745 patients with a mean age of 65.9 ± 12.2 yr. The mean palliative prognostic index (PPI) score in the last week of life was 8.0 ± 3.8. After adjustment for age, sex, cancer type, and PPI score, RRs were 1.69 (95% CI, 1.17–2.46) for low temperature, 2.57 (1.77–3.77) for high diurnal temperature variation, 2.35 (1.61–3.36) for low humidity, and 1.75 (1.22–2.53) for high levels of sunlight.
Conclusion: Weather conditions may be a predictor of death in terminally ill cancer patients.
Jessup CM, Balbus JM, Christian C et al (2013). Climate change, human health, and biomedical research: analysis of the National Institutes of Health research portfolio. Environ Health Perspect, 121:399-404.
McGeehin MA, Mirabelli M (2001). The potential impacts of climate variability and change on temperature-related morbidity and mortality in the United States. Environ Health Perspect, 109(Suppl 2): 185–189.
Gorjanc ML, Flanders WD, VanDerslice J et al (1999). Effects of temperature and snowfall on mortality in Pennsylvania. Am J Epidemiol, 149:1152-60.
Plavcova E, Kysely J (2010). Relationships between sudden weather changes in summer and mortality in the Czech Republic, 1986-2005. Int J Biometeorol, 54:539-51.
Gerber Y, Jacobsen SJ, Killian JM et al (2006). Seasonality and daily weather conditions in relation to myocardial infarction and sudden cardiac death in Olmsted County, Minnesota, 1979 to 2002. J Am Coll Cardiol, 48:287-92.
Gill RS, Hambridge HL, Schneider EB et al (2013). Falling temperature and colder weather are associated with an increased risk of aneurysmal subarachnoid hemorrhage. World Neurosurg, 79:136-42.
Coventry PA, Grande GE, Richards DA et al (2005). Prediction of appropriate timing of palliative care for older adults with non-malignant life-threatening disease: a systematic review. Age Ageing, 34:218-27.
Kehl KA, Kowalkowski JA (2013). A systematic review of the prevalence of signs of impending death and symptoms in the last 2 weeks of life. Am J Hosp Palliat Care, 30:601-16.
Glare PA, Sinclair CT (2008). Palliative medicine review: prognostication. J Palliat Med, 11:84-103.
Morita T, Tsunoda J, Inoue S et al (1999). The Palliative Prognostic Index: a scoring system for survival prediction of terminally ill cancer patients. Support Care Cancer, 7:128-33.
Morita T, Tsunoda J, Inoue S et al (2001). Improved accuracy of physicians' survival prediction for terminally ill cancer patients using the Palliative Prognostic Index. Palliat Med, 15:419-24.
Bierton C, Cashman K, Langlois NE (2013). Is sudden death random or is it in the weather? Forensic Sci Med Pathol, 9:31-5.
Bart JL, Bourque DA (1995). Acknowledging the weather-health link. CMAJ, 153:941-4.
Nichols L, Saunders R, Knollmann FD (2012). Causes of death of patients with lung cancer. Arch Pathol Lab Med, 136:1552-7.
Plavcova E, Kysely J (2014). Effects of sudden air pressure changes on hospital admissions for cardiovascular diseases in Prague, 1994-2009. Int J Biometeorol, 58:1327-37.
Wolf K, Schneider A, Breitner S et al (2009). Air temperature and the occurrence of myocardial infarction in Augsburg, Germany. Circulation, 120:735-42.
de Pablo F, Tomás C, Rivas Soriano L et al (2009). Winter circulation weather types and hospital admissions for cardiovascular, respiratory and digestive diseases in Salamanca, Spain. Int J Climatol, 29:1692-1703.
Barnett AG, Sans S, Salomaa V et al (2007). The effect of temperature on systolic blood pressure. Blood Press Monit, 12:195-203.
Neild PJ, Syndercombe-Court D, Keatinge WR et al (1994). Cold-induced increases in erythrocyte count, plasma cholesterol and plasma fibrinogen of elderly people without a comparable rise in protein C or factor X. Clin Sci (Lond), 86:43-8.
Inagaki J, Rodriguez V, Bodey GP (1974). Proceedings: Causes of death in cancer patients. Cancer, 33:568-73.
Young A, Chapman O, Connor C et al (2012). Thrombosis and cancer. Nat Rev Clin Oncol, 9:437-49.
Lambert GW, Reid C, Kaye DM et al (2002). Effect of sunlight and season on serotonin turnover in the brain. Lancet, 360:1840-2.
Wutzler A, Mavrogiorgou P, Winter C et al (2011). Elevation of brain serotonin during dying. Neurosci Lett, 498:20-1.
Nguyen JL, Schwartz J, Dockery DW (2014). The relationship between indoor and outdoor temperature, apparent temperature, relative humidity, and absolute humidity. Indoor Air, 24:103-12.
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