Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 2030 2039 EN Doudou Zhao 1. Translational Medicine Center, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, 710061, China 2. Assisted Reproduction Center, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, 710003, China Jie Chen Department of Epidemiology and Biostatistics, School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, 710061, China Xiayang Li Department of Epidemiology and Biostatistics, School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, 710061, China Zhaofang Li Department of Epidemiology and Biostatistics, School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, 710061, China Jingchen Zhang Graduate Department, Xi’an Medical University, Xi’an, Shaanxi, 710021, China Caixia Gao Graduate Department, Xi’an Medical University, Xi’an, Shaanxi, 710021, China Wenbo Hong Graduate Department, Xi’an Medical University, Xi’an, Shaanxi, 710021, China Danmeng Liu 1. Translational Medicine Center, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, 710061, China 2. Assisted Reproduction Center, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, 710003, China Wenhao Shi 1. Translational Medicine Center, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, 710061, China 2. Assisted Reproduction Center, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, 710003, China Juanzi Shi 1. Translational Medicine Center, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, 710061, China 2. Assisted Reproduction Center, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, 710003, China Pengfei Qu 1. Translational Medicine Center, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, 710061, China 2. Assisted Reproduction Center, Northwest Women’s and Children’s Hospital, Xi’an, Shaanxi, 710003, China 3. Central Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Chaoyang, Beijing, China 2023 09 25 2023 12 03 Background: Advanced maternal age decreased success of pregnancy rate in the assisted reproductive technology (ART) treatment. We aimed to investigate the association between age and miscarriages in women who required ART for conception. Methods: A cohort study was conducted using a 10-year sample of 14,898 pregnancy cycles with ART treatment in Xi’an, China. The effects of women’s age on miscarriage were assessed using Poisson regression models. The threshold effect between age and miscarriage was explored through curve fitting. Results: Compared with lower than 30 years, the risks of early miscarriage and miscarriage were higher in the older age groups (early miscarriage: [35-37 years: RR=1.48, 95% confidence interval (CI): 1.26 to 1.74; ≥38 years: RR=2.25, 95% CI: 1.87 to 2.72]; miscarriage: [35-37 years: RR=1.45, 95%CI: 1.24 to 1.69; ≥38 years: RR=2.17, 95%CI: 1.82 to 2.60]). The nonlinear relationship between age and early miscarriage and miscarriages were observed. The risk of early miscarriage and miscarriage rapidly increased with age after the turning point (age=33 years) (<33 years: [early miscarriage: RR=1.02, 95% CI: 1.00 to 1.04; miscarriage: RR=1.02, 95% CI: 1.00 to 1.03]; ≥33 years: [early miscarriage: RR=1.11, 95% CI: 1.08 to 1.13; miscarriage: RR=1.10, 95% CI: 1.07 to 1.13]). Conclusion: Among pregnancy cycles undergoing ART, advanced age is associated with higher risk of early miscarriage and miscarriage, and nonlinear relationship between age and early miscarriage and miscarriage were found. More attention should be paid to the risk of pregnant women with older than 33 years in ART treatment. https://ijph.tums.ac.ir/index.php/ijph/article/view/33265 https://ijph.tums.ac.ir/index.php/ijph/article/download/33265/8342

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 1910 1923 EN Lingyu Kong School of Physical Education, Soochow University, Suzhou, 215021, PR China Zhiqi Zhang School of Physical Education, Soochow University, Suzhou, 215021, PR China Yanyan Li School of Bioscience and Technology, Weifang Medical University, Weifang, 261053, PR China Xinrui Zhu Rehabilitation Medicine Department, Xuzhou Rehabilitation Hospital, Xuzhou, 221009, PR China Jia Fan Rehabilitation Medicine Department, Changzhi People’s Hospital, Changzhi, 046000, PR China Lingyue Meng School of Physical Education, Soochow University, Suzhou, 215021, PR China Qiuxia Zhang School of Physical Education, Soochow University, Suzhou, 215021, PR China 2023 12 12 2024 02 21 Background: Low back pain (LBP) is a prevalent health issue that imposes heavy burdens on personal health status and social healthcare. Dynamic Neuromuscular Stabilization (DNS)/Vojta therapy has demonstrated effectiveness in managing conditions related to musculoskeletal system. However, its effects on individuals with LBP remain incompletely understood. We aimed to evaluate the effects of DNS/Vojta therapy on pain intensity and physical function in individuals with LBP. Methods: A search of studies was conducted on several academic databases from inception through April 13, 2023. This study included clinical trials that evaluated the effects of DNS/Vojta therapy on the outcomes in individuals with LBP. The methodological quality of studies was assessed using PEDro scale, Cochrane Collaboration tool, and ROBINS-I scale. Meta-analysis was performed using Review Manager software (RevMan version 5.4.1, The Cochrane Collaboration, 2020). Results: This systematic review and meta-analysis identified twelve eligible studies, which demonstrated that DNS/Vojta therapy significantly alleviated pain intensity (SMD=-1.09; 95%Cl [-1.74, -0.44]; Z=3.28; P=0.001), reduced disability severity (SMD=-0.91; 95%Cl [-1.48, -0.34]; Z=3.12; P=0.002), and improved quality of life (SMD=1.05; 95%CI [0.14, 1.96]; Z=2.27; P=0.02) in individuals with LBP, while no significant improvements were observed in static and dynamic balance ability or spine flexibility. Conclusion: DNS/Vojta therapy is a promising approach for providing great benefits for individuals with LBP, particularly in terms of reducing pain intensity and disability severity, and improving quality of life, which is worth further in clinical application. https://ijph.tums.ac.ir/index.php/ijph/article/view/33978 https://ijph.tums.ac.ir/index.php/ijph/article/download/33978/8333

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 2160 2162 Keun-Sook Park Department of Nursing, Gwangju Health University, Gwangsan-gu, Gwangju, South Korea Kweon Young Ran Department of Nursing, Chonnam National University, Gwang Ju, South Korea Aeri Jang Department of Nursing, Mokpo National University, Muan-gun, Jeollanam-do, South Korea 2024 04 03 2024 09 03 No Abstract. No Abstract No Abstract. https://ijph.tums.ac.ir/index.php/ijph/article/view/35073 https://ijph.tums.ac.ir/index.php/ijph/article/download/35073/8355

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 2040 2048 Jovana Todorovic Institute of Social Medicine, Faculty of Medicine, University of Belgrade, Dr Subotica 15, 11000 Belgrade, Serbia Zeljka Stamenkovic Institute of Social Medicine, Faculty of Medicine, University of Belgrade, Dr Subotica 15, 11000 Belgrade, Serbia Dejan Nesic Institute of Medical Physiology, Faculty of Medicine, University of Belgrade, Dr Subotica 15, 11000 Belgrade, Serbia Katarina Vojvodic City Institute of Public Health of Belgrade, Belgrade, Serbia Aleksandar Stevanovic Institute of Social Medicine, Faculty of Medicine, University of Belgrade, Dr Subotica 15, 11000 Belgrade, Serbia Pavle Piperac Department of Humanities, Faculty of Medicine, University of Belgrade, Belgrade, Serbia Stefan Dugalic Clinic of Obstetrics and Gynecology, Clinical Centre of Serbia, Belgrade, Belgrade, Serbia Miroslava Gojnic Clinic of Obstetrics and Gynecology, Clinical Centre of Serbia, Belgrade, Belgrade, Serbia Zorica Terzic- Supic Institute of Social Medicine, Faculty of Medicine, University of Belgrade, Dr Subotica 15, 11000 Belgrade, Serbia 2023 05 04 2023 10 31 Background: Certain lifestyle characteristics, such as dietary patterns, physical activity, and maintenance of recommended body weight, low-risk alcohol consumption and non-smoking are associated with the lower likelihood for the development of chronic-non communicable disease in the general population. These lifestyles are called health promoting behaviors (HPBs). We aimed to examine the prevalence of the HPBs among the women of reproductive age in Serbia and the factors associated with the compliance with four or more of these behaviors. Methods: The study was the secondary analysis of the data from the National Health survey in Serbia from 2019 that examined social, health status, mental health (using PHQ-8) and lifestyle characteristics of the general population in Serbia. Results: The prevalence of compliance with four or more HPBs was 22%. Among the HPBs the most frequent was a non-risky alcohol consumption reported by 2585 participants (99.2%), followed by normal weight (2018-69.2%) and non-smoking (1469-69%), daily fruit and vegetables intake (969-33.2%) and sufficient aerobic PA (216-7.9%). Multivariate logistic regression analysis with four or more HPBs as an outcome variable showed that the association of compliance with four or more HPBs with tertiary education (OR 1.91, 95% CI: 1.32-2.76) use of prescription medications (OR: 0.62, 95% CI: 0.44-0.87) and score on PHQ-8 (OR: 0.88, 95% CI: 0.79-0.98). Conclusion: There is a need for deeper promotion of health-related behaviors among all educational and vocational groups, including health promotion activities at the primary health care level, which is available to the entire population. https://ijph.tums.ac.ir/index.php/ijph/article/view/31928 https://ijph.tums.ac.ir/index.php/ijph/article/download/31928/8343

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 1924 1934 EN Norizzati Amsah Department of Public Health Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia Zaleha Md Isa Department of Public Health Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia Norfazilah Ahmad Department of Public Health Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia 2023 09 14 2024 02 10 Background: Type 2 diabetes mellitus (T2DM) is associated with a wide range of health outcomes, including an increased risk of depression and anxiety and a decline in quality of life. Even though the significance of biopsychological factors in the mental health status of T2DM patients has been discussed in other studies, the role of environmental factors has been lacking. Therefore, this review aimed to identify the relationship between environmental factors and mental health status among T2DM patients. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) extension for scoping reviews was utilized in this study. Using predetermined keywords, a systematic search was conducted on three electronic databases from 2005 to 2023, namely, Web of Science, Scopus, and PubMed. Articles written in English, and studies focusing on the research question are among the inclusion criteria. Ten articles were extracted that were relevant to the research question. Results: Poor socioeconomic status, urban areas, the influence of neighborhood, greenness, and air pollution had associations with mental health status among T2DM patients. Conclusion: The possible implications of these factors for mental health demand further research and policy consideration. https://ijph.tums.ac.ir/index.php/ijph/article/view/30370 https://ijph.tums.ac.ir/index.php/ijph/article/download/30370/8334

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 2163 2164 Vjeroslava Slavic Institute for Physical Medicine, Rehabilitation and Rheumatology “Dr Simo Milosevic”, Igalo, Montenegro Danijela Randjelovic Institute for Physical Medicine, Rehabilitation and Rheumatology “Dr Simo Milosevic”, Igalo, Montenegro Dragana Vucic Institute for Physical Medicine, Rehabilitation and Rheumatology “Dr Simo Milosevic”, Igalo, Montenegro Gordana Rajovic Spa and Wellness Center, Chenot Espace, One&Only Portonovi, Herceg Novi, Montenegro Sanja Markovic Institute for Physical Medicine, Rehabilitation and Rheumatology “Dr Simo Milosevic”, Igalo, Montenegro 2023 12 06 2023 12 06 No Abstract. No Abstract. No Abstract. https://ijph.tums.ac.ir/index.php/ijph/article/view/33940 https://ijph.tums.ac.ir/index.php/ijph/article/download/33940/8356

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 2049 2058 Junfeng Zhang Department of Thoracic Surgery, Zhongkegengjiu Hospital of Anhui/Gengjiu Clinical Medical College, Anhui Medical University, Hefei, 230001, China Weiyi Gong Department of Thoracic Surgery, Zhongkegengjiu Hospital of Anhui/Gengjiu Clinical Medical College, Anhui Medical University, Hefei, 230001, China Xinle Wang Department of Thoracic Surgery, Zhongkegengjiu Hospital of Anhui/Gengjiu Clinical Medical College, Anhui Medical University, Hefei, 230001, China Longbo Yang Department of Thoracic Surgery, Zhongkegengjiu Hospital of Anhui/Gengjiu Clinical Medical College, Anhui Medical University, Hefei, 230001, China 2023 09 21 2024 09 03 Background: Long non-coding RN (lncRNAs) have been implicated in lung cancer, but the mechanisms stay unclear. We investigated the theatrical role and mechanism of lncRNA Lung cancer associated transcript 1 LUCAT1 in the malignant progress of lung cancer. Methods: From May 2022 to March 2023, a total of thirty normal and cancerous tissues were collected from patients diagnosed with non-small cell lung cancer at Zhongke Gengjiu Hospital in Anhui Province, China. The human SPC-A1 and A549 cell lines were chosen as the subjects for the relevant cellular experiments in this study. LncRNAs were expressed in a different manner identified by bioinformatics methods, and the expression levels in lung cancer tissues as well as cells were verified by the qRT-PCR assay. The biological role of LUCAT1 in NSCLC was determined by CCK-8, EdU, and transwell assay. Results: The regulation of ubiquitin of P53 by LUCAT1 was studied, which showed that LUCAT1 was significantly elevated in NSCLC cell lines and patients’ tissues (P<0.05). High levels of LUCAT1 promoted the proliferation, invasion, and migration of NSCLC cells. Mechanism studies showed that LUCAT1 was mainly located in the nucleus, which bound to P53 and mediated the ubiquitinated degradation of P53. Meanwhile, LUCAT1 knockdown attenuated the ubiquitination process of P53. In addition, rescue experiments illustrated that LUCAT1 induced the proliferation and invasion of NSCLC cells, and played a key role in the survival and tumorigenicity of NSCLC cells by mediating the ubiquitination of P53. Conclusion: Collectively, LUCAT1 activated the malignant phenotypes of NSCLC cells via regulating P53 ubiquitination, which provided a new idea for the diagnosis and treatment of NSCLC. https://ijph.tums.ac.ir/index.php/ijph/article/view/33259 https://ijph.tums.ac.ir/index.php/ijph/article/download/33259/8344

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 1935 1950 EN Yang He 1. Department of Urology, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, China 2. Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China Abai Xu Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China Li Xiao Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China Ying Yang Department of Hematology, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, China Boping Li Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China Zhe Liu Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China Peng Rao Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China Yicheng Wang Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China Li Ruan Department of Urology, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, China Tao Zhang Department of Urology, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, China 2023 07 29 2024 02 05 Background: Phosphorus metabolism might be associated with tumor initiation and progression. We aimed to screen out the phosphorus metabolism genes related to bladder cancer and construct a clinical prognosis model. Methods: The dataset used for the analysis was obtained from TCGA database. GO and KEGG enrichment analyses were subsequently applied to differentially expressed genes. Consensus clustering was utilized, and different clusters of the tumor immune microenvironment and other features were compared. The phosphorus metabolism-related genes involved in prognosis were screened out by univariate Cox regression, LASSO regression and multivariate Cox regression analysis, and a nomogram was constructed. The performance of the nomogram was validated using TCGA dataset and the GEO dataset, respectively. Results: Overall, 405 phosphorus metabolism-related differentially expressed genes from TCGA database were identified, which were associated with phosphorylation, cell proliferation, leukocyte activation, and signaling pathways. Two clusters were obtained by consistent clustering. After tumor immune microenvironment analysis, significant differences in immune cell infiltration between cluster 1 and cluster 2 were found. Four phosphorus metabolism-related genes (LIME1, LRP8, SPDYA, and MST1R) were associated with the prognosis of bladder cancer (BLCA) patients. We built a prognostic model and visualized the model as a nomogram. Calibration curves demonstrated the performance of this nomogram, in agreement with that shown by the ROC curves. Conclusion: We successfully identified four phosphorus metabolism-related genes associated with prognosis, providing potential targets for biomarkers and therapeutics. A nomogram based on these genes was developed. Nevertheless, this study is based on bioinformatics, and experimental validation remains essential. https://ijph.tums.ac.ir/index.php/ijph/article/view/32707 https://ijph.tums.ac.ir/index.php/ijph/article/download/32707/8335

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 2165 2166 Dong-Il Kim 1. Division of Health and Kinesiology, Incheon National University, Incheon, Republic of Korea 2. Sport Science Institute, Incheon National University, Incheon, Republic of Korea 3. Sports Functional Disability Institute, Incheon National University, Incheon, Republic of Korea 2024 07 03 2024 09 01 No Abstract. No Abstract. No Abstract. https://ijph.tums.ac.ir/index.php/ijph/article/view/35961 https://ijph.tums.ac.ir/index.php/ijph/article/download/35961/8357

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 2059 2068 Eun Jung Lee Department of Social Welfare, School of Social Science, Yonsei University, Seoul, Korea Jee Young Kwak Department of Social Welfare, Korea Soongsil Cyber University, Seoul, Korea Hye Jin Kim Graduate School of Social Welfare, Yonsei University, Seoul, Korea 2023 03 10 2023 11 07 Background: As a health vulnerable group, people with disabilities require more health-promoting behavior than non-disabled people. We aimed to identify the types of health behavior of disabled people and to track the trajectories of stress by the type of health behaviors. Methods: Data came from the Panel Survey of Employment for the Disabled Second Wave by the Employment Development Institute (EDI) in Korea. We used dataset from the first 6 years of the 2nd wave of PSEDSW (2016-2021). The current study analyzed 3,991 subjects. The types of health behavior were identified through latent class analysis (LCA) and the trajectories of stress were estimated through multi-group latent growth modeling using Mplus 8.0. Results: Two types of groups in health behaviors, smoking-drinking group (SD), nonsmoking-less drinking group (NLSD) were derived. Depending on the types of health behavior, the trajectories of stress appeared significantly different: the NLSD had significantly lower stress than the SD in the first year, and this low-level stress trajectory was maintained continuously for 6 years. Conclusion: Health behaviors could be suitable as a stress coping method for people with disabilities. This study suggests that it is necessary to make efforts to create an environment that supports people with disabilities to learn healthier ways to cope with stress. https://ijph.tums.ac.ir/index.php/ijph/article/view/31437 https://ijph.tums.ac.ir/index.php/ijph/article/download/31437/8345

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 1951 1963 Haisheng Luo Department of Traditional Chinese Medicine, Baisha Li Autonomous County People's Hospital, Baisha, 572800, Hainan, China Chunying Jing College of Traditional Chinese Medicine, Hainan Medical University (Hainan Academy of Medical Sciences), Haikou, 571199, Hainan, China Hongbo Liu College of Traditional Chinese Medicine, Hainan Medical University (Hainan Academy of Medical Sciences), Haikou, 571199, Hainan, China 2024 04 16 2024 06 27 Background: We aimed to examine how electroacupuncture and manual acupuncture affect treatment results, pain levels, and joint function in individuals with knee osteoarthritis. Methods: Research was carried out in various databases including PubMed, Medline, Embase, CENTRAL, and CNKI. Following the "Cochrane manual", the risk of bias of included RCTs was assessed. A funnel plot was utilized to evaluate any potential bias in the publications. The impact size was indicated by the average discrepancy along with its 95% confidence interval. Results: The EA group showed a higher effectiveness rate (P = 0.001) and a lower WOMAC pain score (P < 0.00001) compared to the control group. The EA group had a lower WOMAC pain score compared to the SA/exercise group and the group that received manual acupuncture. The WOMAC pain score was significantly lower in the EA group compared to the manual acupuncture group under intense electroacupuncture stimulation (P < 0.0001). The WOMAC pain score was significantly lower in the EA group compared to the manual acupuncture group when weak current acupuncture was applied (P = 0.0001). However, no significant difference in WOMAC function score between EA and control group. Conclusion: Comparison to manual acupuncture, placebo acupuncture, and exercise training, electroacupuncture enhanced the effectiveness of treating KOA and decreased the WOMAC pain score in patients with KOA. The level of pain relief achieved may be linked to the strength of the current stimulation. However, electroacupuncture had no significant effect on WOMAC function score. https://ijph.tums.ac.ir/index.php/ijph/article/view/35185 https://ijph.tums.ac.ir/index.php/ijph/article/download/35185/8336

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 2069 2078 EN Izzet Ulker Department of Nutrition and Dietetics, Faculty of Health Sciences, Erzurum Technical University, Erzurum, Turkey Nihal Gordes Aydogdu Department of Public Health Nursing, Faculty of Health Sciences, Erzurum Technical University, Erzurum, Turkey 2023 10 11 2024 04 04 Background: Dietary habits are influenced by environmental factors. Among these environmental factors are the place of residence, cultural characteristics, food accessibility, and economic status, which can all contribute to changes in the dietary pattern. Migration is another factor that can influence changes in the aspects mentioned above. We aimed to assess the dietary habits of individuals who have migrated from Turkey to Germany in comparison to those living in Turkey. Methods: In this descriptive and cross-sectional study, 254 individuals were enrolled with 102 individuals in Germany and 152 individuals in Turkey between April 2022 and July 2023. The data collection tools included Socio-demographic Characteristics Forms, Dietary Habits and Health Status Forms, and Food Consumption Frequency Forms. The data was collected online via Google Forms. Results: There were statistically significant differences in the consumption frequency of processed meats, meat and poultry, sweetened beverages, sugar, desserts and pastries, vegetables, fruits, eggs and grains, olive oil, sunflower oil, hazelnut oil, grains, dairy products, coffee, starch, and carbonated beverages between the two groups (P<0.05). Statistically significant differences were not found in terms of butter and tea consumption frequency. Conclusion: Overall, the study results have revealed significant differences in dietary habits between Turks living in Germany and those living in Turkey. The most noteworthy dimension of these differences is that individuals living in Turkey exhibit a stronger adherence to the Mediterranean dietary pattern, while those living in Germany tend to follow a Western dietary pattern. https://ijph.tums.ac.ir/index.php/ijph/article/view/33436 https://ijph.tums.ac.ir/index.php/ijph/article/download/33436/8346

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 9 2024 09 03 1964 1975 Shiva Khaleghparast Cardiovascular Nursing Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Majid Maleki Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Fereidoun Noohi Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Mahmood Sheikh Fathollahi Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Yasaman Khalili Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Yeganeh Pasebani Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Farnaz Rafiee Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Fahimeh Farrokhzadeh Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran Sajjad Biglari Maastricht University Medical Center MUMC+, Department of Clinical Genetics, Maastricht, The Nederland Saeideh Mazloomzadeh Cardiovascular Nursing Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran 2023 10 13 2251-6085 50 8 2021 07 22 1635 1641 Jianqiao Xu Department of Pulmonary & Critical Care Medicine, Chinese People Liberation Army (PLA) General Hospital, Beijing, China Yongqiang Chen Department of Medical Data, Beijing Renheguangtong (RHGT) Information Co., Ltd. Beijing, China Jiang Wang Department of Pulmonary & Critical Care Medicine, Chinese People Liberation Army (PLA) General Hospital, Beijing, China Guixiu Yang Department of Pulmonary & Critical Care Medicine, Chinese People Liberation Army (PLA) General Hospital, Beijing, China Peng Yan Department of Pulmonary & Critical Care Medicine, Chinese People Liberation Army (PLA) General Hospital, Beijing, China Zhimei Duan Department of Pulmonary & Critical Care Medicine, Chinese People Liberation Army (PLA) General Hospital, Beijing, China Lixin Xie Department of Pulmonary & Critical Care Medicine, Chinese People Liberation Army (PLA) General Hospital, Beijing, China Guoxin Mo Department of Pulmonary & Critical Care Medicine, Chinese People Liberation Army (PLA) General Hospital, Beijing, China 2021 05 26 2021 07 22 Background: Some patients discharged automatically are classified as terminal discharge, while their clinical outcome is survival, disrupting the results of clinical research. Methods: The data of this study were taken from inpatients admitted to the ICU of the First Medical Center of the People's Liberation Army General Hospital, Beijing, China from 2008-2017. We collected the data regarding medications used over the three days before discharge from the group of patients who survived and the group of patients who died, and the outcomes of all patients were recalculated by three classification algorithms (AdaBoosting, Pearson correlation coefficient, observed to expected ratio-weighted cosine similarity). Our basic assumption is that if the classification result is death but the actual in-hospital outcome is survival, the associated patient was likely terminally discharged. Results: The coincidence rate of the outcomes calculated by the AdaBoosting algorithm was 98.1%, the coincidence rate calculated by the Pearson correlation coefficient was 61.1%, and the coincidence rate calculated by the observed to expected ratio-weighted cosine similarity was 93.4%. When the three classification methods were combined, the accuracy reached 98.56%. Conclusion: The combination of clinical rules and classification methods has a synergistic effect on judgments of patients’ discharge outcomes, greatly saving time on manual retrieval and reducing the negative influence of statistics or rules. https://ijph.tums.ac.ir/index.php/ijph/article/view/25075 https://ijph.tums.ac.ir/index.php/ijph/article/download/25075/7321

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1564 1576 Mahasti Alizadeh Social Determinant of Health Research Center, Health Management and Safety Promotion Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran 2. Department of Community and Family Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran Morteza Ghojazadeh 1. Research Center for Evidence-Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran 2. Medical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Reza Piri 1. Medical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, Iran 2. Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark Mohammad Mirza-Aghazadeh-Attari 1. Medical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, Iran 2. Medical Radiation Sciences Research Group, Tabriz University of Medical Sciences, Tabriz, Iran Sahar Mohammadi Department of Emergency Medicine, Faculty of Medicine, Iranshahr University of Medical Sciences, Iranshahr, Iran Mohammad Naghavi-Behzad 1. Department of Community and Family Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran 2. Department of Clinical Research, University of Southern Denmark, Odense, Denmark 2019 11 04 2021 02 02 Background: Breast cancer is responsible for up to 25% of all cancers in Iran. The age at diagnosis of Iranian breast cancer patients starts a decade earlier than most of developed countries. This study aimed to evaluate the mean age at diagnosis of Iranian breast cancer patients. Methods: In this systematic review and meta-analysis, the mean age at diagnosis of Iranian breast cancer patients and its pattern between 2008 and 2017, were evaluated. All papers with age at diagnosis of histopathological verified breast cancer patients were considered eligible to enter to the analysis. We used databases including Medline/PubMed, Scopus, Embase, Cochrane Library, Iranmedex and SID for the search process. The meta-analysis was performed only on studies with separate data for female patients, using random-effects model, Mantel and Haenszel method and the Comprehensive Meta-analysis software. Results: Finally, 92 studies with 19,784 patients (both-genders) were included. The mean age at diagnosis had increased from 47.93 (2008) to 49.91 (2016) years. The meta-analysis was done on 78 studies containing of 15,071 female patients and the mean age at diagnosis was 46.76±1.19. There was a wide range of age at diagnosis within different provinces. The mean age at Hamadan and Khuzestan provinces were the lowest and highest, respectively (42.48±7.96 vs. 51.00±11.47). The heterogeneity of studies was statistically significant (I2=99.744). Conclusion: Mean age at diagnosis of Iranian women with breast cancer was 46.76±1.19. There was an increasing pattern in mean age of diagnosis at breast cancer patients within the past 10 years. https://ijph.tums.ac.ir/index.php/ijph/article/view/18860 https://ijph.tums.ac.ir/index.php/ijph/article/download/18860/7314

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1735 1737 Nasrin Borumandnia Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Hamid Alavi Majd Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran Naghmeh Khadembashi Department of English Language, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran Hojat Alaii Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2019 03 13 2019 04 20 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/16564 https://ijph.tums.ac.ir/index.php/ijph/article/download/16564/7336

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1642 1647 EN Thuan Lao Department of Pharmaceutical and Medical Biotechnology, Faculty of Biotechnology, Ho Chi Minh City Open University, Ho Chi Minh City, Vietnam Minh Nguyen Cho Ray Hospital, Ho Chi Minh City, Vietnam Dung Nguyen University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam Thuy Le Department of Pharmaceutical and Medical Biotechnology, Faculty of Biotechnology, Ho Chi Minh City Open University, Ho Chi Minh City, Vietnam 2020 03 03 2020 05 29 Background: The upregulation of miRNA-155 (miR-155) has been associated with oncogenesis of many human tumors, including nasopharyngeal carcinoma (NPC). However, the profile of miR-155 in Vietnamese NPC patients has not been investigated. The current study aimed to evaluate the miR-155 expression and assess whether miR-155 is a potential biomarker for diagnosis of NPC in Vietnamese patients. Methods: In current case-control study, total of RNA was isolated from 60 biopsy NPC samples and 60 non-cancerous swab samples were analyzed by Reverse-transcription PCR, qualitative Real-time PCR. Results: The frequency of miR-155 detection were 78.33%, 15.0% in NPC and non-cancerous samples (P<0.05), respectively. The miR-155 expression level was 4.92 times higher in tumor samples than non-cancerous sample. Conclusion: Taken together, miR-155 in NPC was upregulated. It may serve as a potential biomarker for NPC in the Vietnamese population. https://ijph.tums.ac.ir/index.php/ijph/article/view/19929 https://ijph.tums.ac.ir/index.php/ijph/article/download/19929/7322

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1577 1585 EN Sajjad Bahariniya Health Services Management, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Farzan Madadizadeh Center for Healthcare Data Modeling, Departments of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 2020 12 10 2021 04 21 Background: Nowadays, statistical methods are used frequently in research articles. This review study aimed to determine the statistical methods used in original articles published in Iranian journal of public health (IJPH). Methods: Original articles in the period 2015 to 2019 from volumes 44 to 48 and numbers 1 to 12 were reviewed by a 3-member committee consisting of a statistician and two health researchers. The statistical methods, sample size, study design and population, type of used software were investigated. Multiple response analysis (MRA), Kruskal–Wallis test and Spearman correlation coefficient were used to data analysis. All analyzes were performed in SPSS21 software. Significant level was set at 0.05. Results: Statistical population in most of the articles were related to human samples at the field level (36% and 297 articles). 66.6% (549 articles) had the sample size less than 500 cases. Study design in most of them were analytical observational 56.2% (464 cases). Acceptance period was 115.5 ± 52.27 days. All the mentioned variables had no significant relationship with the acceptance period (P>0.05). Both among the total tests and the articles, the highest rate of use of statistical methods was related to descriptive statistical method (34.4%, 75.8% and 532 articles), also, the highest use of tests was related to chi square test  and t-test( (29%(450 articles)). Conclusion: Study design in most of the articles were analytical, to increase thematic diversity, accepting different articles seems necessary. The statistical tests, which used in most articles, were simple, so accepting articles with advanced statistical methods is recommended. https://ijph.tums.ac.ir/index.php/ijph/article/view/23132 https://ijph.tums.ac.ir/index.php/ijph/article/download/23132/7315

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1738 1739 Saeed Khaleghi Department of Nursing, School of Nursing & Midwifery, Alborz University of Medical Sciences, Karaj, Iran Ali Sadeghi Moghaddam Department of Nursing, School of Nursing & Midwifery, Dezful University of Medical Sciences, Dezful, Iran Yaser Moradi Patient Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran Hossein Jafarizadeh Patient Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran Mostafa Ghalavand Department of Career Counseling, Faculty of Psychology and Education, Allame Tabatabai University, Tehran, Iran Mohsen Poursadeghiyan Social Determinants of Health Research Center, Ardabil University of Medical Sciences, Ardabil, Iran 2. Department of Occupational Health Engineering, School of Health, Ardabil University of Medical Sciences, Ardabil, Iran Seyed Habibollah Kavari Department of Rehabilitation Management, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran 2018 12 27 2019 02 02 No Abstrct https://ijph.tums.ac.ir/index.php/ijph/article/view/15727 https://ijph.tums.ac.ir/index.php/ijph/article/download/15727/7337

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1648 1657 Huilan Bao The Endocrinology Department of Jinhua People’s Hospital, ZheJiang, China 2021 06 28 2021 07 22 Background: To promote the treatment effects and self-management behaviors of the patients with type 2 diabetes mellitus (T2DM) during the COVID-19 pandemic, this study empirically investigated the relationship among family support (FMS), mental resilience (MR) and diabetic distress (DD) in patients with T2DM. Method: Overall, 256 patients with T2DM from the Department of Endocrinology, Jinhua People’s Hospital, ZheJiang, China were selected and measured for their perceptions of FMS, MR and DD from 2019-2020. Based on the measurements, the difference and correlation matrix under different background variables were studied by one-way variance and correlation analysis. A structural equation was used to analyze the causal path among the measurements. Results: Patients that differ in marital status, annual family income, medical insurance level, number of complications, and with/without insulin injection therapy were significantly different in their perception of FMS, MR and DD. FMS and MR had a significant negative correlation with DD. FMS used MR as an intermediary variable that affected DD. Conclusion: Diabetes education, improved medical insurance levels, and targeted psychological consultation for patients could effectively improve their MR and alleviate DD. https://ijph.tums.ac.ir/index.php/ijph/article/view/25399 https://ijph.tums.ac.ir/index.php/ijph/article/download/25399/7323

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1740 1742 Ramin Hamidi Farahani School of Medicine, AJA University of Medical Sciences, Tehran, Iran Meysam Mosallaei School of Medicine, AJA University of Medical Sciences, Tehran, Iran Ebrahim Hazrati School of Medicine, AJA University of Medical Sciences, Tehran, Iran Naeim Ehtesham Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Bahram Pakzad Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Mehrdad Nasrollahzadeh Sabet School of Medicine, AJA University of Medical Sciences, Tehran, Iran Emran Esmaeilzadeh School of Medicine, AJA University of Medical Sciences, Tehran, Iran 2021 02 27 2021 04 03 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/24016 https://ijph.tums.ac.ir/index.php/ijph/article/download/24016/7338

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1658 1667 Bing Bai School of Economics and Management, Shenyang Agricultural University, Shenyang, Liaoning, China Yan Zhang School of Economics and Management, Shenyang Agricultural University, Shenyang, Liaoning, China Yanbo Liu School of Economics and Management, Shenyang Agricultural University, Shenyang, Liaoning, China 2021 06 19 2021 07 22 Background: The emergence of COVID-19 in 2020 has brought dramatic impacts to the global economy. The resulting health crisis and widespread fear have triggered labor shortage problems such as high job vacancy rate and low labor participation rate. Thus, how to increase the labor supply has become a hotspot among scholars. We aimed to analyze the influences of public medical insurance system on labor health status and supply. Method: Using the China Health and Nutrition Survey five-phase panel data, the new rural cooperative medical system was taken as an example to empirically analyze the influences of public medical insurance system on the individual health status and labor supply via the panel Tobit model and panel binary Logit model. The analysis revealed the mediating effect of health status. Results: First, Public medical insurance system could significantly improve individual health status. Second, public medical insurance system will lengthen the labor supply time and elevate the labor supply rate by improving individual health status. Third, the influences of public medical insurance system on labor health status and supply vary with gender and age. Conclusion: Public medical insurance system will generate positive influences on labor health status and labor supply. Hence, perfecting the public medical insurance system is able to mitigate the negative impacts of population aging and pandemic on the labor supply. https://ijph.tums.ac.ir/index.php/ijph/article/view/25324 https://ijph.tums.ac.ir/index.php/ijph/article/download/25324/7324

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1668 1677 Zahra Sheikh Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Amir Amani Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran Hamid Reza Basseri Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Seyed Hassan Moosa Kazemi Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mohammad Mehdi Sedaghat Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Kamal Azam Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Majid Azizi Department of Horticultural Sciences, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran Fatemehzahra Amirmohammadi Department of Horticultural Sciences, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran 2019 12 15 2020 05 05 Background: Mosquito species are highly considering as disease transmission as well as nuisance insects. One of the principal strategy to protect human from the mosquito bites is repellent agents. This study aimed to assess repellency of two organic essential oils, Eucalyptus globulus and Syzygium aromaticum from bites of malaria vector, Anopheles stephensi. Methods: The study was conducted in 2019-2020. The components of essential oils of E. globulus and S. aromaticum was determined using gas chromatography/mass spectrometry. The unfed female mosquitoes aged 2-5 d old were used in all experiments. In vivo Klun and Debboun module bioassays were utilized on human-volunteer skin. The essential oils at serial concentrations were used to find repellent efficacy against Anopheles landings and bites. To find the synergistic effect, four combinations of the essential oils were tested. Results: The main composition of E. globulus essential oil was 1,8-Cineol (78.20%), whereas that of S. aromaticum essential oil was 2-methoxy-3-(2-propenyl) (77.04%). Based on minimum effective dose (≤1% biting), 10% (v/v) of E. globulus showed high landing repellency (77.78%), whereas minimum effective dose of S. aromaticum at concentration of 1% had high landing repellency (88.89%). Among four combinations, the ratio of 1:1 of E. globulus (10%):S. aromaticum (1%) showed the most landing repellency (94.44%). Conclusion: The combinations of two essential oils had the most potential repellency effect against landing of mosquitoes. As essential oils are eco-friendly with less irritation for human skin, E. globulus and S. aromaticum essential oils are recommended as effective and safe mosquito repellents. https://ijph.tums.ac.ir/index.php/ijph/article/view/19204 https://ijph.tums.ac.ir/index.php/ijph/article/download/19204/7325

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1678 1686 EN Maryam Ranjbar 1. Department of Psychology and Social Sciences, Institute for Humanities and Social Studies, Tehran, Iran 2. Social Determinants of Health Research Center, University of Social Welfare and Rehabilitation, Tehran, Iran Ali Akbar Soleimani Department of Psychology, University of Science and Culture, ACECR, Institute for Humanities and Social Studies, Tehran, Iran Bahram Saleh Sedghpour Faculty of Educational Sciences, Shahid Rajaee Teacher Training University, Tehran, Iran Farahnaz Mohammadi Shahbolaghi Social Determinants of Health Research Center, University of Social Welfare and Rehabilitation, Tehran, Iran Douglas Paton School of Psychological and Clinical Sciences, Charles Darwin University, Darwin, Northern Territory, Australia Mehdi Noroozi School of Psychological and Clinical Sciences, Charles Darwin University, Darwin, Northern Territory, Australia 2018 07 25 2018 12 15 Background: People are still not prepared for earthquakes in vulnerable areas although preparedness considered an effective way of reducing the disastrous consequences. A proper tool was needed to assess the predicting factors of mitigation behaviors in a large vulnerable community who speak Persian. This study aimed to introduce the valid and reliable Persian version of public intention to prepare against earthquakes. Methods: Translation, validation and reliability checking articulated according to the standard methodology for Forward-Backward translation and psychometric evaluation. Totally, 369 Tehran households were selected through stratified random sampling from Oct 2016 to Jun 2017. Exploratory Factor Analysis used to check the construct validity of all scales. Results: Face, content and construct validity of all scales confirmed (S-CVR: .65) and (S-CVI/Universal: .98). The finalized Persian version (69 items in 8 scales) showed good reliability over time in test-retest (ICC: .92) and high internal consistency both in the pilot (α: .94) and main studies (α: .94). No significant floor and ceiling effects were found in any of scales. Conclusion: Persian version of Earthquake Public Intention to Prepare is applicable as a valid and reliable instrument for research regarding disaster preparedness in Persian speaking communities. https://ijph.tums.ac.ir/index.php/ijph/article/view/14167 https://ijph.tums.ac.ir/index.php/ijph/article/download/14167/7326

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1687 1696 Shahram Moradi Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran Ghobad Moradi Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran Bakhtiar Piroozi Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran Ebrahim Ghaderi Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran Daem Roshani Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran Arian Azadnia 1. Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran 2. Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran 2019 09 27 2020 01 22 Background: We aimed at estimating the burden of cancer in Kurdistan Province, western Iran during 2011-2017. Methods: In this cross-sectional study, incidence data extracted from the cancer registry system and death data were extracted from the system of registration and classification of causes of death of Kurdistan Province. We applied the WHO’ methods to calculate the disability-adjusted life year (DALYs). Results: The burden of cancer increased from a DALYs of 12309 in 2011 to 13969 in 2017, the YLL from 11644 in 2011 to 12951 in 2017 and the YLD from 665 in 2011 to 1018 in 2017. The top five cancers, according to DALYs (%) in both sex during 2011-2017 were: stomach (25%), lung (14%), liver (9%), esophagus (6%), and colon (6%). The most burden of cancer related to gastrointestinal tract (54% vs. 45%). Totally, more than 25% of DALYs were related to stomach cancer. Conclusion: The increasing DALYs of cancer in Kurdistan Province is one of the major public health concerns as in most developed countries. More than half of the burden of cancer in the Kurdistan Province is related to gastrointestinal tract. Stomach cancer, is accounting for more than 25% of the burden in both sexes. Urgent policy, management and public health measures such as general education, screening, early detection and effective treatment are recommended to reduce the burden of cancers and especially gastrointestinal tract malignancies. https://ijph.tums.ac.ir/index.php/ijph/article/view/18469 https://ijph.tums.ac.ir/index.php/ijph/article/download/18469/7327

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1697 1704 EN Fatemeh Esfahanian Department of Endocrinology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran Mojgan Mirabdolhagh Hazaveh Department of Internal Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran Laya Hooshmand Garehbagh Department of Endocrinology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran Kowsar Falahati Clinical Genetics Department, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran Mitra Ataei Clinical Genetics Department, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran Mohammad Hossein Sanati Clinical Genetics Department, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran Zohreh Jadali Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2020 01 19 2020 05 05 Background: The purpose of present study was to investigate mitochondrial DNA copy number (mtDNAcn) and mtDNA damage in peripheral blood of patients with Hashimoto's thyroiditis (HT) and healthy controls (HC). Methods: The relative mtDNAcn and oxidative DNA damage in this case-control study were measured in peripheral blood of 50 patients with Hashimoto’s thyroiditis and 50 healthy controls using quantitative real-time PCR. The study was conducted in Tehran University of Medical Sciences hospital, Tehran, Iran in 2018. Results: HT patients had significantly higher mitochondrial DNA copy number and mitochondrial oxidative damage than the comparison group. Conclusion: These data suggest the possible involvement of mitochondria and oxidative stress in the pathophysiology of HT. https://ijph.tums.ac.ir/index.php/ijph/article/view/19484 https://ijph.tums.ac.ir/index.php/ijph/article/download/19484/7328

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 8 2021 07 22 1705 1712 Razieh Bidhendi Yarandi Department of Biostatistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Mohammad Hossein Panahi Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2020 02 01 2020 03 29 Background: Cancer is one of the most important causes of death in the world and has an increasing trend globally. We aimed at investigating the five leading cancers in Iranian women based on a 10-year history of cancer registry reports and illustrating the trends in all cancer sites and breast cancer as the top leading one from 2003 to 2015. Methods: Data were obtained from national cancer registry study. Age-Specific Incidence Rate (ASR) data were obtained from Iran’s annual national cancer registry reports between 2003 to 2010 and 2014 to 2015. Using Joinpoint regression, we analyzed incidence trends over time for all cancer sites and the top leading cancer from 2003 to 2015.