Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 799 808 Mehmet Çelik Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, University of Harran, Şanlıurfa, Turkey Yeliz Çiçek Department of Infectious Diseases and Clinical Microbiology, Bingol State Hospital, Bingol, Turkey Ebru Atalay Department of Infectious Diseases and Clinical Microbiology, Cizre Dr. Selahattin Cizrelioğlu State Hospital, Şırnak, Turkey Deniz Altındağ Department of Infectious Diseases and Clinical Microbiology, Cizre Dr. Selahattin Cizrelioğlu State Hospital, Şırnak, Turkey Fethiye Akgül Department of Infectious Diseases and Clinical Microbiology, Batman Training and Research Hospital, Batman, Turkey Fatma Ürkmez Department of Infectious Diseases and Clinical Microbiology, Kırıkkale Yüksek İhtisas Hospital, Kırıkkale, Turkey Esra Gürbüz Department of Infectious Diseases and Clinical Microbiology, SBU Van Training and Research Hospital, Van, Turkey Ahmet Şahin Department of Infectious Diseases and Clinical Microbiology, Dr. Ersin Arslan Training and Research Hospital, Gaziantep, Turkey Sevda Özdemir Al Department of Infectious Disease and Clinical Microbiology, Turhal State Hospital, Tokat, Turkey Seval Bilgiç Atlı Department of Infectious Disease and Clinical Microbiology, Turhal State Hospital, Tokat, Turkey Sevil Alkan Department of Infectious Diseases and Clinical Microbiology,Faculty of Medicine,University of Canakkale Onsekiz Mart,Canakkale, Turkey Davut İpek Department of Infectious Diseases and Clinical Microbiology, Mardin Training and Research Hospital, Mardin, Turkey Serpil Oğuz Mızrakçı Department of Infectious Diseases and Clinical Microbiology, Gaziantep LIV Hospital, Gaziantep, Turkey Mehmet Reşat Ceylan Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, University of Harran, Şanlıurfa, Turkey Pınar Yürük Atasoy Department of Infectious Diseases and Clinical Microbiology, Ankara City Hospital, Ankara, Turkey Mustafa Kasım Karahocagil Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, University of Kırşehir Ahi Evran, Kırşehir, Van, Türkiye 2023 05 02 2023 09 28 Background: Brucellosis is one of the most common zoonotic infections. Although culture is the gold standard diagnostic method, bacterial growth in blood cultures may not always occur due to various factors. We aimed to investigate demographic, clinical, and laboratory findings that may have predictive significance for bacteremia in brucellosis. Methods: Patients older than 18 years of age followed up with a diagnosis of brucellosis between 2012 and 2022 were included in this retrospective multicenter study. They were divided into two main subgroups according to their Brucella species reproductive status as bacteremic and non-bacteremic. Results: A total of 743 patients, 370 (49.80%) bacteremic and 373 (50.20%) non-bacteremic brucellosis patients, were enrolled. The mean age of the bacteremic group (36.74 years) was lower than the non-bacteremic group (43.18 yr). High fever, chills/cold, sweating, nausea, vomiting, and weight loss were more common in the bacteremic group. In the bacteremic group, white blood cell count, platelet count, hemoglobin level, mean platelet volume, eosinophil, and neutrophil counts were lower, and lymphocyte, erythrocyte sedimentation rate, aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, and ferritin levels were higher. According to the receiver operating characteristic (ROC) analysis, when the cut-off value of ferritin was considered 67, it was the parameter with the strongest predictive significance in Brucella bacteremia. Conclusion: High ferritin level, low eosinophil count, and increased erythrocyte sedimentation rate were determined as the most critical laboratory findings in predicting bacteremia in brucellosis. https://ijph.tums.ac.ir/index.php/ijph/article/view/31912 https://ijph.tums.ac.ir/index.php/ijph/article/download/31912/8208

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 05 747 759 Arief Iman 1. Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Yogyakarta, Indonesia 2. Health Polytechnic of the Ministry of Health, Tasikmalaya, Indonesia Hari Josef Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Yogyakarta, Indonesia Ariani Pertiwi Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Yogyakarta, Indonesia Lutfan Lazuardi Faculty of Medicine, Public Health and Nursing, Gadjah Mada University, Yogyakarta, Indonesia Lia Nurcahyani 1. Health Polytechnic of the Ministry of Health, Tasikmalaya, Indonesia 2. Health and Disaster Emergency Center, Poltekkes Kemenkes Tasikmalaya, Indonesia Faizul Hasan School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan 2023 06 22 2023 09 25 Background: Health information systems are critically important in disaster management. It supports disaster management activities and the information needed for decision-making support. We aimed to evaluate comprehensively published literature on disaster health information systems designed to identify and extract the required framework and components. Methods: A systematic review approach was used to systematically seek, screen, and synthesize data extracted from papers on using health information systems in disasters from the electronic databases (Scopus, PubMed, ProQuest, and SAGE) with no limit up to Jan 2022 following the PRISMA declaration for reporting. The inclusion criteria consisted of full-text journal articles, publications in English, and studies focusing on disaster health information systems, critically evaluated articles using the Joanna Brigg Institute (JBI). Content analysis was used to analyze extracted data. Results: Of 998 identified references, 18 articles were finally included and analyzed in this study and they are good quality according to appraisal results using JBI. Most reports described research of development or working prototypes and working framework; only two referred to early research or proposed design or framework. Of 18 articles; identified into 3 themes; 4 DHISs in pre-disaster, thirteen DHISs used during the disaster, and one DHIS in post-disaster were identified. Conclusion: All the systems have a design or framework starting from strategies and plans, information flow, disaster management, and operation engagement, and involve all stakeholders, including the community. Its systems are supported by the latest technology and methods and the principles of integration and interoperability to obtain a DHIS that can assist decision-making processes. https://ijph.tums.ac.ir/index.php/ijph/article/view/32409 https://ijph.tums.ac.ir/index.php/ijph/article/download/32409/8203

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 967 968 EN Sang-Hyup Song Department of Sports Health Care, Dankook University, Cheonan, Republic of Korea Namwoong Kim Division of Health and Kinesiology, Incheon National University, Incheon, Republic of Korea Jupil Ko Division of Health and Kinesiology, Incheon National University, Incheon, Republic of Korea 2023 03 27 2024 04 08 It is a letter to the editor (no abstract) No Abstract. https://ijph.tums.ac.ir/index.php/ijph/article/view/31572 https://ijph.tums.ac.ir/index.php/ijph/article/download/31572/8225

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 809 817 Min-Jeong Park School of Nursing, Kunsan National University, Gunsan, Republic of Korea Hwee Wee School of Nursing, Kunsan National University, Gunsan, Republic of Korea 2022 10 10 2024 04 08 Background: Middle-aged women have lower health-related quality of life (HRQoL) than men, and women's participation in economic activities is an important issue. In this study, the middle-aged female population was classified by economic activity participation to explore HRQoL and to identify related factors. Methods: We obtained data from the 2017 Korea Health Panel Survey (N = 1857 women aged 50–64 years), analyzed with chi-squared tests, t-tests, analyses of variance, and multiple regression analyses. HRQoL was measured with the Euro QoL-5 Dimensions index, and four demographic factors, four health behavior factors, and ten health status factors were entered. Results: HRQoL was lower in the economically inactive group compared to the active group. Education, physical activity, chronic disease, vision problem, dental problem, activity restriction, frustration, and anxiety were associated with HRQoL in both groups. Spouse and household income were additional predictors identified only in the economically inactive group, and the 10 factors explained 36.0% of the variance. In the economically active group, drinking, sleeping time, hearing problem, stress, and depression were additional predictors identified, and the 13 factors explained 23.0% of the variance. Conclusion: Healthcare providers should consider both common predictors between economically active and inactive middle-aged women as well as predictors that were unique to each group to improve their HRQoL. https://ijph.tums.ac.ir/index.php/ijph/article/view/30048 https://ijph.tums.ac.ir/index.php/ijph/article/download/30048/8209

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 760 773 Yanwen Ding Outpatient Surgical Center, Zibo First Hospital, Zibo, 255200, China Yuxin Xu Department of Endocrinology, Zibo First Hospital, Zibo, 255200, China Xiujuan Tan Department of Intervention Chemotherapy, Zibo First Hospital, Zibo, 255200, China Mohammad Alizadeh Department of Medical Surgical Nursing, Nasibeh Nursing & Midwifery School, Mazandaran University of Medical Sciences, Sari, Iran Hamzeh Alizadeh Genetics Research Center, Department of Genetics and Breeding, the University of Guilan, Rasht, Iran 2023 05 18 2023 10 31 Background: Several observational studies have suggested that maternal exposure during pregnancy to arsenic is associated with the risk of preterm birth (PTB); however, available evidence is inconsistent. Therefore, we aimed to explore the relation of maternal exposure to arsenic to PTB risk. Methods: A comprehensive systematic search was carried out from inception to April 2023 in PubMed and Scopus to retrieve all relevant studies. A pooled odds ratio (OR) with corresponding 95% confidence interval (CI) was employed using a random effects model to test the association. Results: As a result, 14 eligible studies, with 12,619 participants, were included in the meta-analysis. Overall, the pooled OR of all analyzed studies indicated that higher maternal arsenic exposure is significantly related to the 1.12-fold increased odds of PTB (OR = 1.12, 95% CI = 1.04-1.21), with a remarkable heterogeneity across studies (P = <0.001, I2 = 70.9%). This association was found in prospective cohort studies (OR = 1.15, 95% CI = 1.05-1.26), but not in non-cohort studies. In the stratified analysis, the majority of subgroups supported the association of arsenic with PTB. Conclusion: Maternal exposure to arsenic during pregnancy is directly linked to the odds of PTB. Future studies are suggested to investigate the effectiveness of specific measures to decrease exposure to arsenic in high-risk communities, particularly in pregnant women. https://ijph.tums.ac.ir/index.php/ijph/article/view/32080 https://ijph.tums.ac.ir/index.php/ijph/article/download/32080/8205

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 969 971 Shirin Ebrahimi Department of Psychology, Faculty of Human Science, Islamic Azad University Tabriz Branch, Tabriz, Iran Naeimeh Moheb Department of Clinical Psychology, Faculty of Medicine, Tabriz Medical Sciences, Islamic Azad University, Tabriz, Iran Marziyeh Alivandi Vafa Department of Psychology, Tabriz Branch, Islamic Azad University, Tabriz, Iran 2023 06 29 2023 08 12 No Abstract.No Abstract. No Abstract. https://ijph.tums.ac.ir/index.php/ijph/article/view/32499 https://ijph.tums.ac.ir/index.php/ijph/article/download/32499/8226

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 818 827 Wei Guofang Rehabilitation Nursing Department, Rainbow Fish College of Rehabilitation Nursing, Hangzhou Vocational and Technical Col-lege, Hangzhou, 310000, China Wei Zhang Nursing Department, Affiliated Hospital, Hangzhou Normal University, Hangzhou, 310015, China Zhen Zhu Orthopedics Department, The Second Affiliated Hospital, Zhejiang University of Traditional Chinese Medicine, Hangzhou, 310053, China 2024 02 17 2024 04 08 Background: COVID-19 infection is transmitted easily and quickly, exposing medical care workers, especially nursing workers, to tremendous stress. Therefore, identifying the factors influencing the sleep quality of nurses and implementing corresponding interventions are conducive to improving the sleep quality of nurses and enhancing their nursing quality. Methods: Form September to December 2022, a survey-based evaluation was conducted on 1074 front-line clinical nurses randomly selected from three hospitals in Zhejiang Province, China. Based on the survey results, 152 nurses were selected and randomly divided into the experimental group and the control group, with 76 nurses in each group. A 2-month psychological intervention based on the self-transcendence theory was conducted, and the two groups were compared before and after the intervention. Results: The average PSQI score of nurses was 7.19±3.65, with 471 of them suffering from poor sleep (PSQI>7), accounting for 45.46%. In addition, 57.10% of the nurses were under excessive stress, whereas 62% of them had a Self-Rating Anxiety Scale score of ≥50. After the intervention, the PSQI score of the experimental group was significantly lower than that of the control group, with the difference being statistically significant (P<0.05). Conclusion: Clinical nurses in tertiary hospitals have poor sleep quality and more severe stress and anxiety problems during COVID-19 than during non-epidemic periods. Clinical interventions based on the self-transcendence theory can effectively improve the sleep quality of nurses. Results of this study provide reference for enhancing the sleep quality of nurses and ensuring their physical and mental health during epidemic. https://ijph.tums.ac.ir/index.php/ijph/article/view/34646 https://ijph.tums.ac.ir/index.php/ijph/article/download/34646/8210

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 774 784 EN Rehmaita Malem Department of Nursing, Faculty of Science, Technology and Health, Bina Bangsa Getsempena University, Banda Aceh, Indonesia Ristiani Ristiani Department of Midwifery, Nusantara Midwifery Academy 2000, Jakarta, Indonesia Muhibbullah Puteh Department of Nursing, Faculty of Health Sciences, Cut Nyak, University of Science Dhien Langsa, Langsa, Indonesia 2023 07 19 2023 09 09 Background: Brisk walking exercise is an aerobic exercise with the moderate intensity that can reduce the risk in people with hypertension. This systematic review and meta-analysis aimed to investigate the effects of interventions related to brisk walking and blood pressure reduction in hypertensive patients. Methods: Search strategy through the PubMed, Science Direct, ProQuest, and Google Scholar databases limited from 2018 to 2023. The components measured are systolic blood pressure and diastolic blood pressure. This study uses the Black and Downs checklist to measure the quality of the study, which consists of 3, namely high quality, medium quality, and low quality. Effect size analysis of the study used the standard mean difference between brisk walking exercise and not doing brisk walking exercise. Results: The results of the identification of the database obtained 1700 articles, then limited by title, year, abstract (n = 381), and full-text article feasibility (n = 76) to obtain nine articles included. Nine articles were included in the systematic review and meta-analysis by study quality: six studies of high quality, 2 of medium quality, and 1 of low quality. Systolic blood pressure had a substantial effect size in all studies (P<0.05; SMD: -0.55) while diastolic blood pressure had an effect medium size (P=0.05; SMD: 0.13). Conclusion: Brisk walking exercise can significantly reduce blood pressure in people with hypertension—recommendations for the future to carry out community-based physical activity in improving physical health, including heart health. https://ijph.tums.ac.ir/index.php/ijph/article/view/32506 https://ijph.tums.ac.ir/index.php/ijph/article/download/32506/8206

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 976 977 Sang Soo Kim Department of Physical Education, Keimyung University, Daugu, South Korea Yu-Ree Yi Department of Physical Education, Busan National University of Education, Busan, South Korea Sung-Bum Ju Department of Physical Education, Busan National University of Education, Busan, South Korea 2022 12 01 2023 01 22 No Abstract No Abstract. No Abstract. https://ijph.tums.ac.ir/index.php/ijph/article/view/30525 https://ijph.tums.ac.ir/index.php/ijph/article/download/30525/8228

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 828 836 Zorana Babic Faculty of Medical Sciences University of Kragujevac, Kragujevac, Serbia Nemanja Rancic Center for Clinical Pharmacology, Medical Faculty of the Military Medical Academy, University of Defense, Belgrade, Serbia Sanja Ilic Department of Dermatovenerology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Snezana Corovic Faculty of Medical Sciences University of Kragujevac, Kragujevac, Serbia Vesna Milicic Department of Dermatovenerology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Gordana Djordjevic Department of Epidemiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Ognjen Djordjevic Department of Epidemiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Sladjana Ilic Department of Dermatovenerology, General Hospital “Medical System Belgrade”, Belgrade, Serbia Svetlana Radevic Department of Social Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia 2024 02 12 2024 04 08 Background: We aimed to investigating the sex-specific and age-specific melanoma mortality trends observed on the territory of Serbia between 2000 and 2021. Methods: This population-based study used data from the Statistical Office of the Republic of Serbia database during the period 2000–2021. The calculation of the gender and age-standardized rates (ASR) was performed. We used a regression analysis complete with linear trend model. Results: The mean ASR was 1.77 per 100,000 people, meaning that male mortality rates (2.24 per 100,000) was higher than female mortality rates (1.34 per 100,000). During the observation period, a rising trend in mortality from melanoma skin cancer was reported. Observed by gender, the change of melanoma mortality trend was significant in men (P=0.021), but not in women (P=0.747). The annual growth rate of ASRs values was 1.43%. A increase in the melanoma mortality rate was observed since 2000 by 2.44% annually in males and by 2.79% annually in females. Mortality rates were increasing in both sexes as they aged, and the greatest number of deaths was recorded in the group of those aged 80 yr or above (16.25 per 100,000 for men; 10.45 per 100,000 for women). Conclusion: Our study findings underline the importance of launching more effective public health awareness campaigns to educate people about the dangers of melanoma and its symptoms’ detection along with establishing a diagnosis at an early stage of the disease, especially among male patients and those at an advanced age. https://ijph.tums.ac.ir/index.php/ijph/article/view/34615 https://ijph.tums.ac.ir/index.php/ijph/article/download/34615/8211

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 785 798 EN Jiaxian Shao School of Management, Shandong Second Medical University, Weifang, Shandong, China Yuncong Yu School of Management, Shandong Second Medical University, Weifang, Shandong, China Cheng Cheng WeiFang Mental Health Center, Weifang, Shandong, China Min Gao School of Management, Shandong Second Medical University, Weifang, Shandong, China Xiaona Li School of Management, Shandong Second Medical University, Weifang, Shandong, China Dongping Ma School of Management, Shandong Second Medical University, Weifang, Shandong, China Wenqiang Yin School of Management, Shandong Second Medical University, Weifang, Shandong, China Zhongming Chen School of Management, Shandong Second Medical University, Weifang, Shandong, China 2023 06 13 2023 11 26 Background: We aimed to analyze the prevalence of depression among the global public during COVID-19, identify its influencing factors in order to provide reference, and help safeguard public mental health. Methods: A comprehensive literature on global public depression in various countries during the COVID-19 pandemic was obtained through electronic searches of PubMed, Web of Science, and other databases, combined with literature tracing from Dec 2019 to Mar 2023. Then a meta-analysis was conducted using the random effects model by Stata 16.0. The heterogeneity was evaluated by I2. Subgroup analysis, sensitivity analysis, and meta-regression analysis were used to explore the sources of heterogeneity and the factors influencing public depression. Egger's test was used to test publication bias. Results: Overall, 68 articles with 234,678 samples were included in the study. Analysis revealed that the overall prevalence of depression among the population during COVID-19 was 32.0% (95% CI: 29.0%-35.0%). Of these, marital status (OR=0.65, 95% CI: 0.47-0.87), presence of infected cases (OR=2.45, 95% CI: 1.82-3.30), and fear of being infected by the virus (OR=9.31, 95% CI: 6.03-14.37) were the main factors influencing people’s depression and the main source of heterogeneity. Conclusion: The prevalence of depression among the global public is at a high level during COVID-19. The prevalence of depression among people unmarried, divorced, or widowed, surrounded by infected cases, contact infection cases, and worried about being were higher than others. https://ijph.tums.ac.ir/index.php/ijph/article/view/32289 https://ijph.tums.ac.ir/index.php/ijph/article/download/32289/8207

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 972 975 Hee-Tae Roh Division of Sports Science, College of Arts and Sports, Sun Moon University, Asan, Chungcheongnam-do, Korea Taikyeong Jeong School of Artificial Intelligence Convergence, Hallym University, Chuncheon, Korea 2024 02 04 2024 04 04 No Abstract No Abstract No Abstract. https://ijph.tums.ac.ir/index.php/ijph/article/view/34534 https://ijph.tums.ac.ir/index.php/ijph/article/download/34534/8227

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 837 845 Huafeng Li Medical Genetics Department, Linyi Women and Children’s Health Care Hospital, Linyi 276000, China Yongli Li Medical Genetics Department, Linyi Women and Children’s Health Care Hospital, Linyi 276000, China Yanli Zhang Medical Genetics Department, Linyi Women and Children’s Health Care Hospital, Linyi 276000, China Jinping Zhu Medical Genetics Department, Linyi Women and Children’s Health Care Hospital, Linyi 276000, China Yuqiang Huang Medical Genetics Department, Linyi Women and Children’s Health Care Hospital, Linyi 276000, China 2023 07 26 2024 04 08 Background: We aimed to compare the difference of the chromosomal abnormalities using karyotype analysis and chromosomal microarray (CMA) as well as to evaluate their application in different prenatal diagnosis indications. Methods: Overall, 3007 pregnant women with prenatal diagnosis indications from Medical Genetics Department of Linyi Women and Children’s Health Care Hospital, who underwent standard G-banded karyotype analysis and CMA, were enrolled from 2018-2022. G-banded karyotype analysis and CMA were undergone simultaneously. All fetuses with genetic variants were enrolled for further analyzing. The frequency and differences of chromosomal abnormalities of the two methods were compared in different prenatal diagnosis indications groups. Results: CMA improved 4.09% (123/3007) of genetic changes compared karyotype analysis. CMA is on par with karyotyping for detection of aneuploidies and gross unbalanced rearrangements. Serological screening and ultrasound abnormalities were the main indications of prenatal diagnosis. The detection rate of chromosomal abnormalities was highest in non-invasive prenatal testing (NIPT) abnormal group. In the ultrasound abnormality group, the detection rate of genetic variants in nuchal translucency (NT) increased group was higher than other subgroups and there was statistically significant difference in the detection rate of pCNVs. CMA can detect 5.57% (40/718) more genetic abnormalities in ultrasound abnormality group on the normal karyotype. CMA improved 0.67% (20/3007) of genetic changes with clinically significant compared karyotype, brought 3.42% (103/3007) of variants with uncertain significance (VOUS). Conclusion: CMA identified additional, clinically significant genetic variants on the basis of normal karyotype analysis, brought a proportion of unclear significant variants. All the pregnant women accepted amniocentesis should be informed about their characteristics of karyotype analysis and CMA by genetic counselors. https://ijph.tums.ac.ir/index.php/ijph/article/view/32683 https://ijph.tums.ac.ir/index.php/ijph/article/download/32683/8212

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 846 854 Sara Samim Laboratory of Pharmacology, Neurobiology, Anthropobiology, and Environment, Cadi Ayyad University, Faculty of Sciences Sem-lalia, Marrakech, Morocco Mohamed Loukid Laboratory of Pharmacology, Neurobiology, Anthropobiology, and Environment, Cadi Ayyad University, Faculty of Sciences Sem-lalia, Marrakech, Morocco Saloua Lamtali 1. Laboratory of Pharmacology, Neurobiology, Anthropobiology, and Environment, Cadi Ayyad University, Faculty of Sciences Sem-lalia, Marrakech, Morocco 2. Higher Institute of Nursing and Health Techniques, Marrakech, Morocco 2022 11 28 2023 06 19 Background: Obesity is becoming a real challenge for public health among pregnant women. This study aimed to identify sociodemographic and lifestyle risk factors and outcomes linked to maternal obesity and overweight. Methods: A cross-sectional study was carried out from Nov 2021 to Dec 2022 in the maternity health facility of Mohammed VI Hospital, as well as in one of the main health centers with a delivery unit in Marrakech, Morocco. Parturients were divided into four categories according to their pre pregnancy BMI: underweight, normal weight, overweight and obese. We used the chi-square test (χ²) to analyze the sociodemographic and lifestyle factors associated with maternal obesity and overweight. The same tool was utilized to explore maternal and neonatal complications. Results: Overall, 400 parturient women with singleton pregnancies were included in the study. The prevalence of overweight and obesity was 29.8% and 31.5% respectively. Maternal age, type of housing, practicing sports, feelings about pregnancy were correlated with an increased risk of maternal obesity and being overweight. The risks of gestational diabetes, hypertension, anemia, cesarean delivery, and fetal macrosomia were higher among overweight and obese women compared to normal weight ones. The differences were significant (P<0.05). Conclusion: Maternal overweight and obesity are strongly linked with socio-economic, lifestyle, and psychological factors which can lead to serious complications for both mother and baby. Further research is needed to develop appropriate preventive measures and interventions for maternal obesity and overweight. https://ijph.tums.ac.ir/index.php/ijph/article/view/30507 https://ijph.tums.ac.ir/index.php/ijph/article/download/30507/8213

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 855 866 Lei Shao Department of Gynecology, the Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China Wanqiu Liu Department of Gynecology, the Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China Chunyan Zhang Department of Gynecology, the Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China Wei Ma Qiqihar City Hospital of Traditional Chinese Medicine South Department of Gynecology, Qiqihar, China Xiao Yu Department of Obstetrics and Gynaecology, the Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China Jing Han Department of Gynecology, the Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China Xiaojuan Wang Department of Gynecology, the Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China 2023 05 22 2023 08 12 Background: We started with RNA-seq analysis and aimed to investigate the possibility of secretory protein matrix metalloproteinase-3(MMP3) as a new diagnosis and therapeutic target in cervical cancer. Methods: The study was conducted on Nov 2021 at the Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China. Through conjoint analysis of gene expression data as well as survival rate data, we explored the potential secretary proteins associated with cervical cancer carcinogenesis. One hundred patients aged 38-72 years with clinical stage I-IV cervical cancer, and 100 age-matched healthy women were included. The expression changes in serum of clinical patients was detected. We knockdown or overexpressed the secretory proteins then explored its influence on biological function of cervical cancer cells. Results: By cross-analysis of The Cancer Genome Atlas (TCGA) database and MetazSecKB database, MMP3 gene was most significantly upregulated in cervical cancer patients (P < 0.05). Furthermore, MMP3 protein was remarkably increased in the serum of clinical cervical cancer patients and decreased after receiving treatment. Overexpression of MMP3 in HT-3 cells or culturing new cells using the supernatant of the medium after MMP3 overexpression could increase cell viability (P < 0.05) as well as proliferation (P < 0.05). Knockdown of MMP3 reduced the phosphorylation of PI3K as well as AKT proteins, while the PI3K phosphorylation inhibitors could suppress the impact of MMP3 on increasing cell proliferation as well as viability. Conclusion: MMP3 could be an underlying target for early diagnosis and treat cervical cancer in the future. https://ijph.tums.ac.ir/index.php/ijph/article/view/32103 https://ijph.tums.ac.ir/index.php/ijph/article/download/32103/8214

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 4 2024 04 08 867 877 Vera Simic Department of Nursing, Secondary Medical School, Belgrade, Belgrade, Serbia IirstName> MUSA 1. Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, P.R. China 2. Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, P.R. China 3. Biomedical Research Institute, Darfur College, Nyala, Sudan Tauseef AHMAD 1. Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, P.R. China 2. Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, P.R. China Jin HUI Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, P.R. China Pingmin WEI 1. Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, P.R. China 2. Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, P.R. China 2019 01 04 2019 01 09 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/15795 https://ijph.tums.ac.ir/index.php/ijph/article/download/15795/7177

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 3 2021 02 27 557 565 Dae-Jung LEE Department of Physical Education, Jeonbuk National University, Jeollabuk-do, Korea Byung-Kweon CHANG Department of Physical Education, Korea National University of Education, Chungcheongbuk-do, Korea Seungman LEE Department of Physical Education, College of Education, Korea University, Seoul, Korea 2021 01 28 2021 02 27 Background: We aimed to verify the structural relationship between sports participation, ego-resilience, and health-promoting behavior of Korean adolescents in a pandemic situation. Methods: In Nov 2020, an online survey was conducted with 751 adolescents in Korea. The data obtained through the survey were analyzed in several ways, including frequency, reliability, confirmatory factor, descriptive statistical, and path analyses. Results: Sports participation had a positive effect on ego-resilience and health-promoting behavior, while ego-resilience has a positive effect on health-promoting behavior. Overall, sports participation directly affects health-promoting behavior and that an indirect effect occurs through ego-resilience. Conclusion: Educational institutions such as schools and the Korea Offices of Education should devise various measures so that adolescents growing up in a global pandemic situation can strengthen their health-promoting behavior by securing ego-resilience through participation in various sports. https://ijph.tums.ac.ir/index.php/ijph/article/view/23649 https://ijph.tums.ac.ir/index.php/ijph/article/download/23649/7165

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 3 2021 02 26 492 501 Mahnaz SOLHI Department of Education and Health Promotion, School of Health, Iran University of Medical Sciences, Tehran, Iran Esmaeil FATTAHI Department of Education and Health Promotion, School of Health, Iran University of Medical Sciences, Tehran, Iran Zahra Sadat MANZARI Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran Prakash C. GUPTA Healis-Sekhsaria Institute for Public Health, Navi Mumbai, Maharashtra, India Mehdi KARGAR Department of Health Education & Promotion, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran Parisa KASMAEI Health and Environment Research Center, Department of Health Education and Promotion, School of Health, Guilan University of Medical Sciences, Rasht, Iran Hadis BARATI Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2020 04 16 2020 08 20 Background: Smokeless tobacco use is a public health problem in some parts of the world. The major objective of this study was to investigate the reasons and factors of consumption. Methods: A content analysis was conducted on articles for the past thirty years (1989-2019). We reviewed and selected 400 abstracts of original articles from PubMed databases by the search strategy, and reviewed one by one. Among these, 45 abstracts were selected, in which the patterns of use, the reasons for using, and the determinants and predictors were described. Eleven papers were selected based on the results and related to the research objectives. The results of these articles were evaluated precisely word by word and phrase by phrase with content analysis method and inductive approach. Results: The reasons for the use of smokeless tobacco fell in two main themes: socio-cultural structure; and, beliefs, each contained Sub-themes such as "culture and living conditions", "laws", "family and peer relationships", "beliefs related to psychological" and "beliefs related to physical influences", "beliefs", "The role of harm perceptions ". Conclusion: There was a difference between beliefs, cultures and social conditions among the people about using of smokeless tobacco and the association of these factors is investigated in future studies. We also suggest for the prevention and control of smokeless tobacco use, cultural norms and beliefs will need to address adequately. https://ijph.tums.ac.ir/index.php/ijph/article/view/20372 https://ijph.tums.ac.ir/index.php/ijph/article/download/20372/7158

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 3 2021 02 27 630 631 M. Aminur RAHMAN 1. Department of Fisheries and Marine Bioscience, Faculty of Biological Science and Technology, Jessore University of Science and Technology, Jessore-7408, Bangladesh 2. World Fisheries University Pilot Programme, Pukyong National University (PKNU), 365 Sinseon-ro, Nam-gu, Busan 48547, Republic of Korea Rahim AHMADI Department of Physiology, Faculty of Basic Science, Hamadan Branch, Islamic Azad University, Hamadan, Iran Azam GOHARI Department of Physiology, Faculty of Basic Science, Hamadan Branch, Islamic Azad University, Hamadan, Iran Sahar ESHGHJOO 1. Department of Biology, Faculty of Basic Sciences, Research and Sciences Branch, Islamic Azad University, Tehran, Iran 2. Department of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Texas, USA 2018 11 18 2019 01 08 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/15354 https://ijph.tums.ac.ir/index.php/ijph/article/download/15354/7178

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 3 2021 02 27 566 572 Hong JIANG 1. Department of Nursing, Guangzhou Red Cross Hospital ,Ji-Nan University, Guangzhou, 510220, P.R. China 2. Department of Nursing, Cancer Hospital of Shantou University, Medical College, Shantou, 515031, P.R. China Yanwen LIANG Department of Nursing, Guangzhou Red Cross Hospital ,Ji-Nan University, Guangzhou, 510220, P.R. China Xinmei LIU Department of Nursing, Guangzhou Red Cross Hospital ,Ji-Nan University, Guangzhou, 510220, P.R. China Donghong YE Department of Nursing, Guangzhou Red Cross Hospital ,Ji-Nan University, Guangzhou, 510220, P.R. China Mengmiao PENG Department of Nursing, Guangzhou Red Cross Hospital ,Ji-Nan University, Guangzhou, 510220, P.R. China Yun CHEN 1. Department of Pharmacy, Guangzhou Red Cross Hospital, Ji-Nan University, Guangzhou, 510220, P.R. China 2. Clinical Pharmacy Research Center, Shantou University Medical College, Shantou, 515031, P.R. China Shuang CHEN 1. Department of Pharmacy, Guangzhou Red Cross Hospital, Ji-Nan University, Guangzhou, 510220, P.R. China 2. Clinical Pharmacy Research Center, Shantou University Medical College, Shantou, 515031, P.R. China Wanying CHEN 1. Department of Pharmacy, Guangzhou Red Cross Hospital, Ji-Nan University, Guangzhou, 510220, P.R. China 2. Clinical Pharmacy Research Center, Shantou University Medical College, Shantou, 515031, P.R. China Haiyan LI Department of Nursing, Guangzhou Red Cross Hospital ,Ji-Nan University, Guangzhou, 510220, P.R. China Shuyao ZHANG 1. Department of Pharmacy, Guangzhou Red Cross Hospital, Ji-Nan University, Guangzhou, 510220, P.R. China 2. Clinical Pharmacy Research Center, Shantou University Medical College, Shantou, 515031, P.R. China 2020 09 01 2020 11 26 Background: To explore the effects of risk factors-based nursing management on the occurrence of pressure sores in hospitalized patients. Methods: From Jan 2018 to Jun 2018, 289 hospitalized patients were divided into pressure sores group [100] and control group [189] for retrospective analysis. Overall, 260 hospitalized patients from Jun 2018 to Dec 2018 were followed up for nursing intervention. Overall 130 patients received risk factors-based nursing case management were in the intervention group, whereas 130 patients who received routine nursing care were in the control group. The chi-square test and t-test were used to compare the count data and the measurement data between groups, respectively. Results: Age, body weight and proportions of patients with impaired nutritional intake, diabetes or stroke in pressure sores group were higher than those in normal group (P<0.05). Hospital stay and operative time in pressure sores group was longer than those in normal group (P<0.05). The frequency of assistant activity in pressure sores group was significantly lower than that in control group (P<0.05).In addition, the score of uroclepsia in pressure sores group was lower than that in normal group (P<0.05). Patients in the intervention group showed lower risk for pressure sores and more satisfied than patients in control group (P<0.001). Conclusion: Advanced age, high body weight, diabetes and stroke, long hospital stay, long operative time, poor nutritional status and severe uroclepsia were independent risk factors of pressure sores. Risk factors-based nursing case management can effectively reduce the occurrence and risk of pressure sores for hospitalized patients. https://ijph.tums.ac.ir/index.php/ijph/article/view/22046 https://ijph.tums.ac.ir/index.php/ijph/article/download/22046/7166

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 3 2021 02 27 632 633 Samaneh YOUSEFLU Department of Midwifery and Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran Soudabeh NIROOMAND Department of Midwifery, Zanjan University of Medical Sciences, Zanjan, Iran Ghazall ROSHANZADEH Department of Midwifery and Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran Anoshirvan KAZEMNEJAD Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran Shahideh JAHANIAN SADATMAHALLEH Department of Midwifery and Reproductive Health, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran 2018 12 06 2018 12 30 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/15543 https://ijph.tums.ac.ir/index.php/ijph/article/download/15543/7179

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 3 2021 02 27 573 582 Parisa REZANEJAD ASL Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran Farid ZAYERI Proteomics Research Center and Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medi-cal Sciences, Tehran, Iran Alireza MOGHISI Deputy General Director for NCDs, National Focal Person for STEPS Survey & Director for Injury Prevention, Ministry of Health and Medical Education, Tehran, Iran 2019 03 26 2019 08 19 Background: Chronic lymphoid leukemia (CLL) is one of the most prevalent types of leukemia, which is responsible for a remarkable mortality rate in the world. This study aimed to investigate the global trend of this cancer from 1990 to 2015 and to determine the relationship between trend of CLL mortality rate and Human Development Index (HDI) throughout the world. Methods: The age-standardized mortality rate data of all countries of the world (per 100,000) were extracted from the GBD database. In addition, the HDI values for the studied countries in different years were obtained from the UNDP database. The statistical analysis was performed using the mixed-effects location-scale model in the SAS software, version 9.4. Results: The findings of the statistical modeling showed a downward slope for CLL Age Standardized Mortality Rate (ASMR) for total world countries ( ). We also find a significant association between CLL ASMR and HDI. Countries with higher HDI had higher level of CLL ASMR in years 1990 to 2015 with a negative slope. Furthermore, countries with lower HDI had Lower level of CLL ASMR with rather fixed rates in this period. Conclusion: These findings showed a decreasing trend of global CLL ASMR in the previous decades, although, the fixed trend of CLL ASMR in countries with low HDI is worrisome. The health policymakers should make more efforts to decrease the mortality due to this cancer in these countries. https://ijph.tums.ac.ir/index.php/ijph/article/view/16674 https://ijph.tums.ac.ir/index.php/ijph/article/download/16674/7167

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 3 2021 02 27 634 636 Roya POURMAJED Department of Microbiology, Islamic Azad University Tonekabon Branch, Tonekabon, Iran Mohammadreza JABBARI AMIRI Department of Medical Mycology and Parasitology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Pezhman KARAMI Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran Azad Khaledi Infectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran 2018 12 24 2018 12 30 None. https://ijph.tums.ac.ir/index.php/ijph/article/view/15693 https://ijph.tums.ac.ir/index.php/ijph/article/download/15693/7180

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 3 2021 02 27 583 591 EN Amir TAJBAKHSH 1. Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran 2. Department of Medical Genetics & Molecular Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mash-had, Iran 3. Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran Zahra FARJAMI 1. Department of Medical Genetics & Molecular Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 2. Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran Abolfazl NESAEI-BAJESTANI Department of Basic Sciences, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran Fahimeh AFZALJAVAN Department of Medical Genetics & Molecular Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Mahdi RIVANDI Department of Medical Genetics & Molecular Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Atefeh MOEZZI 1. Department of Medical Genetics & Molecular Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 2. Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran Soheila ABEDINI Department of Medical Genetics & Molecular Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Mahla ASGHARI Department of Medical Genetics & Molecular Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Mohammad Mahdi KOOSHYAR Department of Hematology-Oncology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran Fatemeh HOMAEI SHANDIZ Cancer Research Center, Mashhad University of Medical University, Mashhad, Iran Alireza PASDAR Department of Medical Genetics & Molecular Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran 2. Division of Applied Medicine, Faculty of Medicine, University of Aberdeen, Foresterhill, Aberdeen, UK 3. Medical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran 2019 07 02 2019 08 05 Background: CC chemokine receptor 5 (CCR5) is introduced as an immune response modulator. The activity of CCR5 influences breast tumour development in a p53-dependent manner. This study aimed to investigate the frequency of CCR5delta32 and its association with the risk of breast cancer in 1038 blood samples in North East of Iran. Methods: In this case-control study, we genotyped 570 control samples and 468 breast cancer patients by a gel electrophoresis-based gap-polymerase chain reaction (gap-PCR) method Mashhad, Iran. The data were analyzed using the SPSS software. Results: Of 570 controls included, 542 (95.09%) had CCR5delta32 wild/wild (W/W) genotype, 28 samples (4.91%) had CCR5delta32 wild/deletion (W/D) genotype and none of them were CCR5delta32 deletion/deletion (D/D) genotype (0%). While 428 samples of patients (91.45%) had CCR5delta32 W/W genotype, 40 samples (8.55%) had CCR5delta32 W/D and CCR5delta32 D/D homozygous was nil (0%) amongst cases. All samples were in the Hardy–Weinberg equilibrium (P>0.05). According to the allele frequency, D allele, as a risky allele, in the cases was more than the control samples (0.0427 vs 0.0245, respectively) (P=0.0206). Hence, W/D genotype may confer a risk effect (OR=1.77, CI: 1.09-2.90; P=0.0206) compared with WW genotype between case and control groups. Conclusion: There is a statistically significant association between CCR5W/D and breast cancer risk. CCR5 may be regarded as a target for the prevention of breast cancer in certain conditions such as interaction with p53 variants, which remains to be further investigated. https://ijph.tums.ac.ir/index.php/ijph/article/view/17576 https://ijph.tums.ac.ir/index.php/ijph/article/download/17576/7168

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 3 2021 02 27 637 639 Habib EMAMI Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti Univer-sity of Medical Sciences, Tehran, Iran Parisa ADIMI NAGHAN Clinical Tuberculosis and Epidemiology Research Center, National Research Institute for Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran Maral EMAMI Surgery Research Unit, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran Fatemeh RAZAVI Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2018 12 11 2018 12 30 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/15572 https://ijph.tums.ac.ir/index.php/ijph/article/download/15572/7181

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 3 2021 02 27 592 597 Reza SHAFIEI 1. Vector-Borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran 2. Department of Pathobiology and Laboratory Sciences, North Khorasan University of Medical Sciences, Bojnurd, Iran Fatemeh TAGHASI Student Research Committee, North Khorasan University of Medical Sciences, Bojnurd, Iran Seyed Ahmad HASHEMI Department of Pathobiology and Laboratory Sciences, North Khorasan University of Medical Sciences, Bojnurd, Iran Yaser PANAHI Laboratory Affairs, Health Assistances, North Khorasan University of Medical Sciences, Bojnurd, Iran Nasir AREFKHAH Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran Mostafa OMIDIAN Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Farzane ARIANFAR Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Farzane ARIANFAR Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Zohreh MOSTAFAVI-POUR Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Bahador SARKARI Basic Sciences in Infectious Diseases Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran 2019 08 03 2019 08 18 Background: Cystic echinococcosis (CE) is one of the most important helminthic parasitic diseases in Iran. The current study aimed to assess the seroprevalence of CE in North Khorasan Province, Northeast of Iran in 2018. Methods: The study was carried out in seven cities of North Khorasan Province. Venous blood samples were collected from 932 individuals referring to health centers of those seven cities. A questionnaire was used to obtain the data regarding the subject's gender, age, residence and risk factors linked to the hydatid cyst. Sera samples were evaluated for anti-hydatid cyst antibodies in an ELISA system, using a recombinant B8/1 antigen of E. granulosus. Results: Of the 932 recruited subjects, 496 (53.2%) were male and 436 (46.8%) were female. The range of participants’ age was between 11 to 83 yr old and the mean age of the subjects was 35.4 (±12.7) years. Anti-hydatid cyst antibodies were detected in the sera of 37 out of 932 subjects, corresponding to a seroprevalence rate of 3.96%. From these, 20 (54.05%) were male and 17 (45.95%) were female. There were no associations between seropositivity to hydatid cyst and age, the gender of the participants, residential areas and having contact with dogs (P>0.05). Conclusion: CE is relatively prevalent throughout the North Khorasan Province in the Northeast of Iran. Rate of CE infection in this Province is somewhat similar to the rate of infection in other parts of the country. https://ijph.tums.ac.ir/index.php/ijph/article/view/17976 https://ijph.tums.ac.ir/index.php/ijph/article/download/17976/7169

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 3 2021 02 27 598 605 Hadi Lotfnezhad Afshar Department of Health Information Technology, School of Paramedical, Urmia University of Medical Sciences, Urmia, Iran Nasrollah JABBARI Department of Medical Physics, Solid Tumor Research Center, School of Paramedical, Urmia University of Medical Sciences, Ur-mia, Iran Hamid Reza KHALKHALI Department of Biostatistics and Epidemiology, Patient Safety Research Center, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran Omid ESNAASHARI Omid Treatment and Research Center, Urmia, Iran 2019 02 02 2019 07 17 Background: The low breast cancer survival rates in less developed countries are critical.