Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 07 950 959 EN Le Thi Vui Department of Population and Reproductive Health, Faculty of Social and Behavioral Sciences, Hanoi University of Public Health, Hanoi ,Vietnam Duong Minh Duc Department of Population and Reproductive Health, Faculty of Social and Behavioral Sciences, Hanoi University of Public Health, Hanoi ,Vietnam Chu Thi Thuy Quynh Department of Population and Reproductive Health, Faculty of Social and Behavioral Sciences, Hanoi University of Public Health, Hanoi ,Vietnam Duong Kim Tuan Department of Epidemiology, Faculty of Fundamental Sciences, Hanoi University of Public Health, Hanoi, Vietnam Nguyen Mai Huong Department of Psychiatry, National Hospital of Pediatrics, Hanoi, Vietnam Nguyen Thi Minh Thanh Department of Research Management and Cooperation, Hanoi University of Public Health, Hanoi, Vietnam Nguyen Minh Hung Department of Science and Technology for Economic Branches, Ministry of Science and Technology, Hanoi, Vietnam Hoang Van Minh Department of Health Policy and Economics, Health Management Training Institute, Hanoi University of Public Health, Hanoi, Vietnam Bui Thi Thu Ha Department of Population and Reproductive Health, Faculty of Social and Behavioral Sciences, Hanoi University of Public Health, Hanoi ,Vietnam 2021 06 25 2022 03 02 Background: Autism Spectrum Disorders (ASDs) are common behavioral syndromes but limited critical evidence in Vietnam. This study aimed to identify ante-, peri- and neonatal factors for ASDs amongst children in Vietnam. Methods: This population-based study applied the cross-sectional design with a multistage sampling in 21 urban and rural districts in seven cities/provinces in Vietnam during 2017-2018. Overall, 42,551 children age 18 to 30 months were enrolled in the study. Two phases of assessment using Modified Checklist for Autism in Toddlers (M-CHAT) for screening and diagnostic assessment using Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria for confirmation. We employed univariate and binary logistic regression to identify. Results: Our study showed a fast-growing trend of ASDs amongst children age 18 and 30 months (75.8 per 10,000 individuals). Nine ante-, peri-, and neonatal factors were associated with ASDs: five factors of antenatal period (history of miscarriage/abortion or stillbirth, children conceived by assisted reproduction technologies, having cold, flu or acquiring virus during pregnancy, having gestational diabetes, toxemia, high blood pressure or pre-eclampsia during pregnancy, and having stress or mental disorders during pregnancy); one factors of perinatal period (mode of delivery); and three factors of neonatal period (jaundice, respiratory distress, and newborn seizures) Conclusion: This first large-scale survey in Vietnam confirms some prenatal, perinatal, and postnatal factors with ASDs amongst children age 18 and 30 months. Future interventions should focus on these factors to early diagnosis and intervention to improve functional outcomes for risky children. https://ijph.tums.ac.ir/index.php/ijph/article/view/25379 https://ijph.tums.ac.ir/index.php/ijph/article/download/25379/7929

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 07 870 879 Milena Corbic Department of Neurology, Agnes Karll Laatzen Hospital, Laatzen, Germany Jasmina Sretenovic Department of Physiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Vladimir Zivkovic 1. Department of Physiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia 2. Department of Pharmacology, First Moscow State Medical University, University I.M. Sechenov, Moscow, Russia Vladimir Jakovljevic 1. Department of Physiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia 2. Department of Human Pathology, First Moscow State Medical University, University I.M. Sechenov, Moscow, Russia Tamara Nikolic Turnic 1. Department of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia 2. Department of Public Health and Healthcare N. A. Semashko, F.F. Erismann Institute of Public Health, First Moscow State Medical University, University I.M. Sechenov, Moscow, Russia 2022 01 12 2023 01 22 Background: Three selective and most used inhibitors of PDE-5- sildenafil, vardenafil and tadalafil- have been successfully used for the treatment of erectile dysfunction. Erectile dysfunction and cardiovascular diseases might be considered as two dissimilar clinical signs of the identical systemic disease. PDE-5 inhibitors can through different models and mechanisms induce vasodilation, decrease apoptosis and cell proliferation, and they are widely present in various tissues that make them promising targets in a range of cardiovascular diseases. Methods: PubMed was explored to identify papers published from 1990-2019, presenting data for the most used PDE-5 inhibitors (sildenafil, tadalafil or vardenafil) in treatment of cardiovascular diseases. Results: This article analyses the therapeutic potentials of PDE-5 inhibitors in cardiovascular diseases and discusses mechanisms, possible risks and limitations. Comparable to earlier studies, newer studies suggest cardioprotective effects of PDE-5 inhibitors, which include different models and mechanisms and do not indicate an increased rate of significant cardiovascular adverse reactions. Dissimilarity in the pharmacokinetics and pharmacodynamics of PDE-5 inhibitors are significant to their risk- benefit profile and clinical use. Some of the studies suggesting infarct size reduction after PDE-5 inhibition described the especially close dose-effect relation, other studies dosage adaptation in drug- drug interactions. Conclusion: PDE-5 inhibitors indicate the encouraging useful effects by ischemia/reperfusion injury, myocardial infarction, cardiac hypertrophy, cardiomyopathy and systolic and diastolic congestive heart failure. Therefore, this and similar reviews can help for additional clinical targeting in the therapy of cardiovascular diseases.   https://ijph.tums.ac.ir/index.php/ijph/article/view/27461 https://ijph.tums.ac.ir/index.php/ijph/article/download/27461/7923

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 1089 1091 Denis Niyazi Department of Microbiology and Virology, Medical University of Varna, Varna, Bulgaria Stephanie Radeva 1. Department of Microbiology and Virology, Medical University of Varna, Varna, Bulgaria 2. Microbiology Laboratory, MHAT “St. Anna” – Varna, Bulgaria Milena Bozhkova 1. Department of Microbiology and Virology, Medical University of Varna, Varna, Bulgaria 2. Laboratory of Clinical Microbiology, UMHAT “St. Marina”- Varna, Bulgaria Dobromira Savova 1. Department of Microbiology and Virology, Medical University of Varna, Varna, Bulgaria 2. Laboratory of Clinical Microbiology, UMHAT “St. Marina”- Varna, Bulgaria Temenuga Stoeva 1. Department of Microbiology and Virology, Medical University of Varna, Varna, Bulgaria 2. Laboratory of Clinical Microbiology, UMHAT “St. Marina”- Varna, Bulgaria 2021 10 27 2022 01 16 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/26700 https://ijph.tums.ac.ir/index.php/ijph/article/download/26700/7943

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 960 968 Ling Zhang Center for Mental Health, Shaoxing University, Shaoxing, China Haibin Wang School of Educational Science, Huangshan University, Huangshan, China Junjie Zhang Center for Mental Health, Anhui University of Chinese Medicine, Hefei, China 2023 02 07 2023 05 08 Background: Middle and primary school teachers are experiencing considerable stress from their careers. However, previous studies on work stress among teachers focused on the influence of various types of stress on individuals but failed to explore the relationship among middle and primary school teachers’ work stress, psychache. We aimed to examine the basic conditions of the challenge-hindrance stress of middle and primary school teachers as well as its relationship with psychache and psychological resilience. Method: A total of 512 middle and primary school teachers from Zhejiang and Anhui in China were enrolled from May to October 2021. The subjects were evaluated with the challenge–hindrance stress questionnaire, psychache scale, and psychological resilience scale. t-test, ANOVA analysis, correlation analysis, and multivariate regression analysis were used to explore the relationship between challenge-hindrance stress and psychache Results: Middle and primary school teachers generally experience high challenge–hindrance stress and psychache. The challenge-hindrance stress had a significantly positive correlation with psychache (r=0.295, 0.439, P<0.01) and a significantly negative correlation with psychological resilience (r＝−0.320, −0.494, P<0.01). Challenge–hindrance stress could be used to significantly predict the psychache. Specifically, challenge stress and hindrance stress could significantly positively predicted the psychache (β=0.295 and β=0.439, respectively). In addition, psychological resilience exerted a partial mediating effect on the relationship between challenge–hindrance stress and psychache. Conclusion: The challenge–hindrance stress of middle and primary school teachers influences their psychache directly as well as indirectly through the mediating effect of psychological resilience.   https://ijph.tums.ac.ir/index.php/ijph/article/view/31163 https://ijph.tums.ac.ir/index.php/ijph/article/download/31163/7930

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 07 880 891 Jiale Yu 1. Graduate School of Physical Education, Myongji University, Yongin 17058, Republic of Korea 2. School of Physical Education, Nanchang Normal University, Nanchang 330032, Jiangxi Province, China Buongo Chun Graduate School of Physical Education, Myongji University, Yongin 17058, Republic of Korea Dongjun Lee Graduate School of Physical Education, Myongji University, Yongin 17058, Republic of Korea Ladan Rokni Asia Contents Institute, Konkuk University, Seoul, Republic of Korea 2023 02 08 2023 04 18 Background: While people’s living standards are improving, the incidence of chronic diseases due to a lack of exercise is increasing. Complex health conditions (e.g., metabolic syndrome) are becoming common, and means to lower their incidence are essential. Methods: This study systematically reviewed the literature and performed a meta-analysis on the effects of Baduanjin exercise on metabolic syndrome-related factors. Using four English databases and three Chinese databases, randomized controlled trials on the effects of Baduanjin exercise on metabolic syndrome were identified. We analyzed whether Baduanjin could alleviate various metabolic syndrome indicators according to our selection guidelines. Results: We found that Baduanjin exercise had positive effects on blood pressure (systolic blood pressure: mean difference (MD)=-6.39; 95% confidence interval (CI): -9.86 to -2.92; I2=12%; diastolic blood pressure: MD=-2.86; 95% CI: -5.96 to -0.23; I2=35%; P=0.07) and total cholesterol (standardized mean (SMD)=-0.55; 95% CI: -1.11 to 0.02; I2=86%; P=0.06), triglyceride (SMD=-0.29; 95% CI: -1.13 to - 0.56; I2=94%; P<0.51), and low-density cholesterol (SMD =-0.33; 95% CI: -0.52 to -0.14; I2=0%; P<0.0007) levels. Conclusion: This evidence shows that Baduanjin exercise provides beneficial effects by improving metabolic syndrome and cardiovascular disease in adults. This suggests that Baduanjin exercise could be an effective alternative or complementary approach to conventional treatments for adults with metabolic problems. Additionally, these findings suggest that more rigorous randomized control trials are needed in the future.   https://ijph.tums.ac.ir/index.php/ijph/article/view/31176 https://ijph.tums.ac.ir/index.php/ijph/article/download/31176/7924

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 1092 1094 Byeongmin Chae Department of Environmental Engineering, Incheon National University, Incheon 22012, South Korea Do Gyun Lee Department of Environmental Engineering, Incheon National University, Incheon 22012, South Korea 2021 10 12 2021 11 29 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/26554 https://ijph.tums.ac.ir/index.php/ijph/article/download/26554/7944

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 969 977 Wiesław Chwała Department of Biomechanics of the University of Physical Education, 31-571 Cracow, Poland Katarzyna Burdacka Department of Recreology and Biological Regeneration of the University of Physical Education, 31-571 Cracow, Poland Robert Walaszek Department of Recreology and Biological Regeneration of the University of Physical Education, 31-571 Cracow, Poland Marcin Burdacki Med Coach, Non-Public Continuing Education Institution, 31-573 Cracow, Poland 2021 10 30 2022 02 23 Background: Dynamic balance monitoring involves the assessment of the muscular control during changes of the centre of gravity location in space above the supporting plane. We aimed to determine the structure of the Y-Balance Test and its accuracy based on measurements of strength and resistance to fatigue of muscles acting on the knee joint under static conditions, as well as joint motion ranges and static balance in girls aged 14 years. Methods: The study included 40 girls aged 14, who attended Gymnasium No. 2 in Cracow (Poland). The research was conducted in October 2020. Postural stability was examined with the use of the YBT. The measurements of muscle strength and knee joint extensor and flexor resistance to fatigue during an isometric contraction were performed in a standard position on the test bench. The measurements of lower extremity joint range of motion were performed in accordance with the SFTR methodology. Static balance was assessed with the use of the modified FBT. Results: The factor structure obtained for both lower extremities has satisfactorily explained the common variance (about 70%) and showed slight differences between the left and right extremities. Conclusion: The factor structure in the group of examined girls suggests a highly hybrid nature of the Y-Balance Test with a wide spectrum of biomechanical variables that have little influence on the measurement results.   https://ijph.tums.ac.ir/index.php/ijph/article/view/26718 https://ijph.tums.ac.ir/index.php/ijph/article/download/26718/7931

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 07 892 902 Jae-hak Do Department of Korean Language and Literature, Kyonggi University, Suwon, Korea Sam-hun Park Asia Contents Institute, Konkuk University, Seoul, Korea 2023 02 03 2023 05 07 Background: Previous research dealt with the concept of ‘hygiene’ in Korea, mainly regarding the modern transition summarized as ‘from regimen to hygiene’, has been based on qualitative research methods. However, because modern Korean language material had been constructed as a corpus with a considerable size, a quantitative approach based on language material has become possible. Through this, the provision of a new implication point can be received. Methods: The Corpus of Modern Korean Magazines, which is a morph-tagged corpus constructed based on 20 kinds of original texts of modern magazines in Korea, was utilized. In this corpus, a list of the co-occurred words of ‘wisaeng [hygiene], yangsaeang [regimen], geongang [health], and cheonggyeol [cleanliness]’, importantly related to the concept of ‘modern hygiene’ and the strength of co-occurrence that was calculated with the t-score, were extracted and analyzed.  Results: Through a quantitative analysis of the corpus base, it was confirmed that the number of the co-occurred words of ‘wisaeng [hygiene]’ decreases and the strength of the co-occurrence gets low.  In contrast, the number of the co-occurred words of ‘geongang [health]’ increases and the strength of the co-occurred words becomes heightened.  Conclusion: Regarding the change after ‘from regimen to hygiene’, an analysis based on the corpus has been attempted. Through the quantitative data, the conversion into ‘from hygiene to health’ was confirmed. Research with such a method proves the need and the feasibility of quantitative research that supplements the previous qualitative analysis.   https://ijph.tums.ac.ir/index.php/ijph/article/view/31130 https://ijph.tums.ac.ir/index.php/ijph/article/download/31130/7947

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 1095 1096 Sung-Bum Ju Department of Physical Education, Busan National University of Education, Busan, South Korea 2020 12 08 2021 01 11 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/23100 https://ijph.tums.ac.ir/index.php/ijph/article/download/23100/7945

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 978 985 Berta Schulz-Bañares Department of Pharmacy, School of Pharmacy, University of Concepcion, Concepcion, Chile Carla González-Norambuena Central Pharmacy, Hospital Las Higueras, Talcahuano, Chile Claudio Muller-Ramirez Department of Pharmacy, School of Pharmacy, University of Concepcion, Concepcion, Chile 2022 09 01 2023 01 09 Background: Poisonings is a preventable public health problem that globally affects the population. We aimed to characterize drug-related acute poisonings occurred in Chile between the years of 2016 and 2020. Methods: A retrospective study of poisonings among hospitalized patients was carried out. Data were obtained from the Medical Outcome Statistical Report database. Inclusion criteria were cases of patients admitted into either public or private healthcare settings with diagnosis of drug-related poisoning according to the WHO ICD-10 codes T30-T50. Statistical analyses were run to establish either significant associations or differences between variables selected in the study. Results: Overall, 12,975 poisonings were identified during the 2016-2020 period. These events corresponded to 0.16% of all national hospital admissions in the study period. Women represented 71.1% of the cases. 76.7% of events were related to intentional poisonings while 7.3% and 16% were accidental and undetermined poisonings respectively. 44.6% of accidental and intentional poisonings occurred at the age of 18-29 yr old. Benzodiazepines (22.8%), antidepressants (11.2%), and acetaminophen (5.1) were the most common drugs associated with poisonings. Average length of hospitalization was between 3.3 and 8.2 days. 0.6% of poisonings resulted in deaths.     Conclusion: Poisonings were characterized by patients’ sex and age, circumstance of exposure, length of hospitalization, and outcome. Poisoning rates were stable along the years with a slight decrease in 2020. Intentional poisonings among young women and men were more common. Most of the cases had favorable outcome for patients.   https://ijph.tums.ac.ir/index.php/ijph/article/view/29695 https://ijph.tums.ac.ir/index.php/ijph/article/download/29695/7932

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 07 903 912 Liming Zhao Department of Vascular Surgery, Liu Zhou People’s Hospital, Guangxi, 545006, China Ying Liu Department of Endocrinology, Affiliated Hospital of Youjiang Medical University for Nationalities, Guangxi, China Ziting Cao Department of Vascular Surgery, Liu Zhou People’s Hospital, Guangxi, 545006, China Jun Wang Department of Vascular Surgery, Liu Zhou People’s Hospital, Guangxi, 545006, China Xin Huo Department of Vascular Surgery, Liu Zhou People’s Hospital, Guangxi, 545006, China 2022 11 07 2023 01 22 Background: Proprotein convertase subtilisin / Kexin type 9 (PCSK9) inhibitors are efficacious lipid-lowering agents. This drug is related to improving the prognosis of patients with cardiovascular disease (CVD). The purpose of this meta-analysis was to systematically analyze the safety and efficacy of PCSK9 inhibitors in all published randomized controlled trials (RCTs). Methods: As of October 25, 2021, we searched PubMed, EMBASE, MEDLINE, Cochrane Library and web of science. Results: From 684 articles, we included 11 trials for meta-analysis, including 52511 participants (26938 in the PCSK9 inhibitor group and 25573 in the control group). In terms of effectiveness, PCSK9 inhibitors reduced the risk of major adverse cardiovascular events(MACE) (OR=0.89, 95% Cl: 0.83-0.95, P=0.0009), but did not significantly reduce the risk of cardiovascular death (OR=0.95, 95% Cl: 0.84-1.07, P=0.38) or all-cause death (OR=0.93, 95% Cl: 0.85-1.03, P=0.18); In terms of safety, PCSK9 did not increase the risk of treatment-emergent adverse events (TEAE)(OR=0.98, 95% Cl: 0.94-1.02, P=0.28). Conclusion: PCSK9 inhibitors can significantly reduce the risk of MACE in patients with high cardiovascular risk, which is well tolerated, but the impact on the risk of death is unclear.   https://ijph.tums.ac.ir/index.php/ijph/article/view/30305 https://ijph.tums.ac.ir/index.php/ijph/article/download/30305/7925

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 1097 1098 Mahdi Mohammadian Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran Abdollah Mohammadian-Hafshejani Modeling in Health Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran 2021 12 10 2022 01 16 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/27135 https://ijph.tums.ac.ir/index.php/ijph/article/download/27135/7946

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 986 994 EN Xiuli Hu Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Miao Qi Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Ping Yuan Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Guojia Qi Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Xiahong Li Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Yanna Zhou Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Xiuquan Shi Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China 2021 09 27 2022 02 23 Background: We aimed to analyze the differences and changing trends of mortality of Injury and Poisoning (IP) between urban and rural areas and gender in China to find out the influencing factors and to propose improvement measures. Methods: IP mortality, population, economy, medical and health information data came from the official website of the National Bureau of Statistics, and basic data on education level came from the Chinese Ministry of Education. Then the differences of the mortality of IP were compared between different areas and gender in China from 2009 to 2019, and the relationships between the mortality changes of IP and education level, GDP per capita, the numbers of practicing physicians, health institutions and urbanization rate were also explored by establishing a ridge regression model. Results: The mortality of IP in rural areas was significantly higher than that of urban areas, and in male was higher than that of female (both P<0.001). Primary school graduates, GDP per capita, the number of practicing physicians, health institutions and urbanization rate had strong correlations (rmin=-0.622) with the mortality of IP. Ridge regression model showed that there was a quantitative relationship between primary school graduates, GDP per capita, the number of practising physicians, health institutions, urbanization rate and the mortality of IP in China. Conclusion: As the difference of working nature, economic development imbalance, psychological and gender, the mortality of IP was significantly different, so the state should take more effective measures to develop the urban and rural areas balanced, and reduce the IP risk in some particular occupations.   https://ijph.tums.ac.ir/index.php/ijph/article/view/26408 https://ijph.tums.ac.ir/index.php/ijph/article/download/26408/7933

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 07 913 923 Niloofar Mohammadzadeh Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran Meysam Rahmani Katigari Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran Rahil Hosseini Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran Shahrbanoo PahlevanyNejad Health Information Technology Department, School of Allied Medical Sciences, Semnan University of Medical Sciences, Semnan, Iran 2022 01 19 2022 09 10 Background: This study was conducted to classify the types of evaluation methods in clinical health technologies based on a systematic review method. Methods: An electronic search was conducted in three scientific databases including Scopus, PubMed and ISI. The search strategy was performed in Jul to Nov 2021 and based on the three main concepts of "evaluation", "technology", "health. This search has been restricted to 10 years (2011-2021). Moreover, it only was limited to English and papers published in journals and conferences proceeding. Results: Overall, 8149 references were identified for title and abstract screening. Full text screening was performed for 2674 articles, with 174 meeting the criteria for study inclusion. Conclusion: Most of the technologies evaluated in these articles were associated with PC-based systems (N=107), and there have been fewer mobile apps (N=67). Most of used technologies were with goals of treatment (43%, N=74) and education (26%, N=45). Among all the methods, the most and the least used methods were usability (66%, N=115) and qualitative (1%, N=2) method, respectively. The most method for health clinical technologies is usability method especially in telemedicine field.   https://ijph.tums.ac.ir/index.php/ijph/article/view/27551 https://ijph.tums.ac.ir/index.php/ijph/article/download/27551/7926

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 995 1007 EN Yunying Cai Department of Endocrinology and Metabolism, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, China Ben Niu Department of Endocrinology and Metabolism, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 65003ex.php/ijph/article/download/27242/7625

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1313 1322 EN Xiaobing Liu School of Economics and Management, Dalian University of Technology, Liaoning, Dalian, China Fulai Gu 1. School of Economics and Management, Dalian University of Technology, Liaoning, Dalian, China 2. The First Affiliated Hospital of Dalian Medical University, Liaoning, Dalian, China Zhaoyang Bai School of Economics and Management, Dalian University of Technology, Liaoning, Dalian, China Qiyang Huang China Academy of Industrial Internet, Beijing, China Ge Ma China Academy of Industrial Internet, Beijing, China 2020 08 14 2021 04 29 Background: The forecasting of daily outpatient visits has significant practical implications in outpatient clinic operation management, not only contributing to guiding long-term resource planning and scheduling but also making tactical resolutions for short-term adjustments on special days such as holidays. We here in propose an effective genetic programming (GP)-based forecasting model to predict daily outpatient visits (OV) in a primary hospital. Methods: In the GP-based model, the holiday-based distance outlier mining algorithm was used to determine the holiday effect. In addition, solar terms were applied as the smallest unit to more accurately determine the impact of a change in the climate on the outpatient volume. A segmental learning strategy also was used to predict the daily outpatient volume for the time series data. Results: The GP-based prediction could more effectively extract depth information from a finite training sample size and achieve a better performance for predicting daily outpatient visits, with lower root mean square error (RMSE) and higher coefficient of determination (R2) values, than the seasonal autoregressive integrated moving average (SARIMA) model in the time range of holidays and the holiday effect. Conclusion: GP-based model can achieve better prediction performance by overcoming the shortcomings of the SARIMA model. The results can be applied to support decision-making and planning of outpatient clinic resources, to help managers implement periodic scheduling of available resources on the basis of periodic features, and to perform proactive scheduling of additional resources. https://ijph.tums.ac.ir/index.php/ijph/article/view/21805 https://ijph.tums.ac.ir/index.php/ijph/article/download/21805/7626

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1323 1330 Ariff Ibrahim Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latiff, Kuala Lumpur, Malaysia Mohd Abdul Manaf Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latiff, Kuala Lumpur, Malaysia Noor Ismail Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latiff, Kuala Lumpur, Malaysia 2020 10 17 2021 02 06 Background: The prevalence of undiagnosed hypertension in Malaysia is 17.2%, which is higher compared to the known case of hypertension (13.1%) reported in 2015. For every two people diagnosed with hypertension, there will be three persons with undiagnosed hypertension; the trend has not changed since 2011. This study aimed to determine the determinants of undiagnosed hypertension among urban community of Kuala Lumpur, Malaysia. Methods: This was a cross-sectional study conducted among 206 participants in Kuala Lumpur, Malaysia from the ongoing Prospective Urban Rural Epidemiology (PURE) project. The samples with complete variable data were taken from the second year of follow-up, starting Jan 2014 till Dec 2015, through convenience sampling. Data were analyzed using descriptive analysis, simple logistic regression, and multivariable logistic regression. Results: Multivariable logistic regression showed that only four determinants were associated with undiagnosed hypertension which were the age group of 35 to 49 yr old (aOR: 5.9, 95% CI: 1.8; 19.1), secondary education level (aOR: 2.3, 95% CI: 1.1; 4.6), normal BMI (aOR: 5.1, 95% CI: 1.5; 16.6), and non-diabetes mellitus (aOR: 5.5, 95% CI: 2.5; 12.0). Conclusion: The determinants of undiagnosed hypertension in this study showed that low-risk groups of hypertension were highly underdiagnosed. The low-risk group of hypertension was easily approached at their working place. Thus, routine health screening and awareness campaigns should be emphasized substantially at the working place to detect undiagnosed hypertension. Early detection will be beneficial as early management can be initiated to prevent further complications.   https://ijph.tums.ac.ir/index.php/ijph/article/view/22535 https://ijph.tums.ac.ir/index.php/ijph/article/download/22535/7627

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1331 1338 Yingying Gong Department of Physical Education, Physical Education Institute, Hunan City University, Yiyang, China Ning Gong Department of Physical Education, Physical Education Institute, Hunan City University, Yiyang, China Zhihui Zhang Department of Physical Education, Physical Education Institute, Hunan City University, Yiyang, China Yang He Hunan City University Haiou Tang Department of Physical Education, Physical Education Institute, Hunan City University, Yiyang, China 2022 04 05 2022 06 08 Background: There are a large number of psychological problems caused by Internet addiction. We aimed to explore the intervention effect of narrative therapy in combination with Pilates exercise on Internet addiction among adolescents. Method: From July 2021 to October 2021, 42 adolescents with Internet addiction selected from four communities in Yiyang City of China were randomly divided into the intervention and control groups with 21 members in each group. The intervention group participated in the intervention of narrative therapy in combination with Pilates exercise eight times, whereas the control group did not receive any intervention. The 12-item General Health Questionnaire, Self-rating Young’s Diagnostic Questionnaire of Internet Addiction, and Positive Affect Subscale were used to measure the psychological indexes of the adolescents before and after the intervention. Results: Compared with those in the control group, the adolescents in the intervention group had an obvious decrease in the degree of Internet addiction with a statistically significant difference before and after the intervention (P < 0.001). After the intervention, the intervention group had significantly higher mental health scores and significantly lower scores for anxiety, depression, social dysfunction, and loss of interest than the control group. After the intervention, the intervention group showed an obvious increase in the score for positive affect with a statistically significant difference before and after the intervention (P < 0.001). Conclusion: The intervention method proposed in this study could effectively solve the problem of Internet addiction among adolescents. https://ijph.tums.ac.ir/index.php/ijph/article/view/28344 https://ijph.tums.ac.ir/index.php/ijph/article/download/28344/7628

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1339 1347 Yunus Beyhan Department of Medical Parasitology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey Cuneyt Albayrak Department of Medical Parasitology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey Irem Guven Department of Medical Parasitology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey 2020 11 23 2021 02 06 Background: Cytokines are protein substances involved in immune response and inflammation regulation, cell growth, tissue repair and natural and adaptive immunity events such as hematopoiesis. Changes in Th1 and Th2 immune responses provide information on the clinical presentation, pathology and diagnosis of diseases. Methods: This study was conducted on 142 patients, aged 18-95 yr and applied to Parasitology Laboratory of Van Yuzuncu Yil Hospital between Aug 2018 and May 2019. Fifty-one of the patients were serologically diagnosed with CE, 53 with a diagnosis of fascioliasis, and 38 as the control group. Serum samples were taken from patients and levels of IL-4, IL-10, TNF α and IFN γ parameters were investigated by ELISA method. Results were evaluated by spectrophotometer and observed which immunologic parameters increased in which infections. Cytokine results were also evaluated according to patient age groups and genders. Chi-square and/or Fisher's exact test were used to evaluate the results. IL-4 response was detected in 50.9%; IL-10 in 44.2%; TNF-α in 43.3% and IFN-γ in 43.3% of CE seropositive patients. Results: IL-4, IL-10, TNF-α and IFN-responses detected in 50.9%, 44.2%, 43.3% and 43.3% of CE patients, and in 43%, 39.2%, 34.4% and 40.6% of fascioliasis patients, respectively. The presence of Th1 and Th2 responses were detected in both infections. There was a significant relationship between fascioliasis and IL-4 response and between CE and IL-4, IL-10 and TNF-α responses (P≤.05). Conclusion: These cytokine levels may provide information about the immune response to infections, and may be useful for early detection of disease and recurrence and monitoring of treatment. https://ijph.tums.ac.ir/index.php/ijph/article/view/22965 https://ijph.tums.ac.ir/index.php/ijph/article/download/22965/7629

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1348 1354 EN Negin Badrooj Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran Seyed Ali Keshavarz Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran Curtis Tilves Department of Epidemiology, School of Public Health, Johns Hopkins University Bloomberg, Baltimore, MD, USA Mir Saeed Yekaninejad Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Sara Pooyan Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran Nasim Ghodoosi Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran Khadijeh Mirzaei Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran 2020 07 13 2021 04 13 Background: The increasing trend of obesity prevalence is a serious health warning for people worldwide. Evaluation of anthropometric measures is essential for explaining individual’s health status. Studies have investigated the effect of diet on inflammation. Empirical Dietary Inflammatory Pattern (EDIP) was recently developed to empirically create a score for overall inflammatory potential of diet. This study aimed to investigate the relationship between EDIP with anthropometric measures in women with overweight and obesity. Methods: In a cross-sectional study, the EDIP score was calculated for 301 participants from their food frequency questionnaire, who referred to health centers in Tehran, Iran in 2018. Anthropometric measures was assessed through multi-frequency bioelectrical impedance analyzer. Results: 49% (95% CI: 40.8 - 57.2) had positive EDIP score. A significant relationship was found between EDIP quartiles with weight (P=0.004), BMI (P=0.012), FM (P=0.013), WC (P=0.003) and WHR (P=0.031). Those individuals in the lowest group of EDIP score had significantly lower weight, Body Mass Index, Fat Mass, Waist Circumference and Waist to Hip Ratio, compared to those with highest inflammation score. Conclusion: A significant relationship was found between EDIP with anthropometric measures in women with overweight and obesity, supporting the hypothesis that an anti-inflammatory diet is associated with decreasing trend of weight, Body Mass Index, Fat Mass, Waist Circumference and Waist to Hip Ratio.   https://ijph.tums.ac.ir/index.php/ijph/article/view/21464 https://ijph.tums.ac.ir/index.php/ijph/article/download/21464/7630

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1355 1363 Nasirudin Javidi 1. Behavioral Sciences Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran 2. Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran Mostafa Ghanei Chemical Injuries Research Center, Systems Biology and Poisoning Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran Khodabaksh Ahmadi Behavioral Sciences Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran Mohammad Javad Ahmadizadeh Behavioral Sciences Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran Abbas Ebadi Behavioral Sciences Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran AND Faculty of Nursing, Baqiyatallah University of Medical Sciences, Tehran, Iran 2020 12 22 2021 04 03 Background: Quality of life is determined by the lifestyle of individuals. If people have a healthy lifestyle, then they have a higher quality of life. What makes a person's lifestyle is the way he thinks. Therefore, if the thinking is healthy, the person's lifestyle will be healthy, and if the thinking is unhealthy, the person's lifestyle will also be damaged, which will reduce the quality of life. Methods: The research method was mixed method in two quantitative and qualitative phases. The research method in the qualitative phase was customary qualitative content analysis, in which the data analysis process was based on the approach of Granheim and Ladman. In the quantitative phase, the psychometric properties of the research scale were measured. This research was conducted from 2016 to 2021 in Iran. The statistical population in the qualitative section was all scientific texts in the form of articles, books and dissertations that were extracted from scientific databases such as ScienceDirect, PubMed, Elsevier, Ebsco, Sid, Magiran. Results: Indicators of intellectual thinking have been mentioned as research results, which are the main components of the new model of thinking. Moreover, the level of thinking was mentioned and Cognitive distortions, cognitive bias, and perceptual errors were mentioned as sources of harm and error. Conclusion: Intellectual thinking has been mentioned as healthy thinking, which is the main factor of a health promotion lifestyle because healthy lifestyle improves the quality of life of people, which is one of the indicators of public health. Therefore, a higher quality of life can be achieved from the model of healthy thinking, which is a new perspective on promoting public health. https://ijph.tums.ac.ir/index.php/ijph/article/view/23272 https://ijph.tums.ac.ir/index.php/ijph/article/download/23272/7631

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1364 1370 Vahid Louhrasby Molecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran Seyed Ali Mirhosseini Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Teh-ran, Iran Reza Golmohammadi Baqiyatallah Research Center for Gastroenterology and Liver Diseases (BRCGL), Baqiyatallah University of Medical Sciences, Tehran, Iran 2020 11 20 2021 02 06 Background: The purpose of this survey was to develop a novel and rapid isothermal nucleic acid based detection assay of Vibrio cholerae by polymerase spiral reaction (PSR) in emergency situations. Methods: The current study was conducted in Baqiyatallah University of Medical Sciences, Tehran, Iran in 2021. The conserved ctxA gene sequence of V. cholerae was used as a target of designed two pairs of primers. Amplification of nucleic acids performed under isothermal temperature of 65 oC in 55 min by using Bst DNA polymerase. PSR amplified products were real-time visualized under UV transilluminator and also on agarose gel electrophoresis. Results: Seven non- V. cholerae bacteria were negative for detection, which indicated the specificity of PSR assay was 100%. A 10- fold serial dilution of V. cholerae genomic DNA was subjected to conventional polymerase chain reaction (PCR) and real-time PCR to compare their sensitivities with PSR. The detection limit of PSR was 3 × 10-5 ng/ μL within 60 min, which 100-fold higher than that of PCR (3 × 10-3 ng/μL), but the sensitivity of real-time PCR was found as same as it. Conclusion: The PSR assay developed in this study can provide a simple, cost-effective, rapid, and precise diagnosis technique in endemic cholera outbreaks, especially in low-income with limited access provinces.   https://ijph.tums.ac.ir/index.php/ijph/article/view/22943 https://ijph.tums.ac.ir/index.php/ijph/article/download/22943/7632

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1371 1380 EN Maryam Askari 1. Genetic and Environmental Adventures Research Center, School of Abarkouh Paramedicine, Shahid Sadoughi University of Medi-cal Sciences, Yazd, Iran 2. Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mohammad Hassan Lotfi Department of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Seyyed Mohammad Azimi Department of Occupational Health, School of Paramedicine, Shahid Sadoughi University of Medical Sciences, Abarkouh, Yazd, Iran Maral Ostovarfar Department of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Hossein Fallahzadeh Research Center of Prevention and Epidemiology of Non-Communicable Disease, Departments of Biostatistics Nand Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Akram Mehrabbeik Genetic and Environmental Adventures Research Center, School of Abarkouh Paramedicine, Shahid Sadoughi University of Medi-cal Sciences, Yazd, Iran Andishe Hamedi Faculty of Epidemiology & Biostatistics, Imam Khomeini Hospital, North Khorasan University of Medical Sciences, Bojnurd, Iran 2020 10 18 2021 02 07 Background: The aim of this study was to evaluate the predictors of osteoporosis in women in Yazd, Iran. Methods: This hospital-based case-control study was performed on 270 women 35-65 yr old (135 case and 135 control) from Mar 2016 to Mar 2017. Case and control were matched in terms of age ± 2 (year) as a group matching. Osteoporosis is defined as a T-score of bone mineral density (BMD) below –2.5 SD. Data were analyzed using SPSS 20 software. Statistical tests included chi-square, student t test and Mann Whitney test .Multiple logistic regression (MLR) which forward method was used for modeling. Results: Odds ratio (OR) of osteoprosis were menarche age>12 yr (OR=3.37, CI:2.29-15.89), history of hysterectomy (OR=13, CI:3.81-44.82), rheumatoid arthritis (RA) (OR=6.58, CI:2.29-18.91) calcium supplements (OR=0.14, CI:0.04-0.41), menopause age <40 (OR=11.84, CI:1.54-90), second smoking (OR=3.38, CI:1.16-9.81) and increase of weight (OR=0.86, CI:0.80-0.94). Conclusion: Predictors of osteoporosis was menarche age >12 yr (3 times), history of hysterectomy (13 times), RA (6.5 times), menopause age <40 (12 times), second smoking (more than 3 times), calcium supplements and weight (protective).   https://ijph.tums.ac.ir/index.php/ijph/article/view/22549 https://ijph.tums.ac.ir/index.php/ijph/article/download/22549/7633

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1381 1388 Sogand Ghasemzadeh Department of Psychology, School of Psychology and Education, University of Tehran, Tehran, Iran Zahra Naghsh Department of Psychology, School of Psychology and Education, University of Tehran, Tehran, Iran Mohammad Gholami Fesharaki Department of Biostatistics, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran 2021 01 22 2021 04 29 Background: Premenstrual Syndrome (PMS) is the experience of some physical and psychological symptoms periodically in the last days of the menstrual cycle that interferes with academic, social and family functioning. We aimed to evaluate the effectiveness of Transdiagnostic Treatment Program (TTP) on clinical symptoms and emotion regulation in girl’s adolescents with PMS. Methods: This experimental trial study was carried out on 32 girls adolescents with PMS referred to two medical centers located in Tehran, Iran from Mar 21, 2019, to Oct. The patients randomized in 2 groups, 1-intervention (n=16, 8 sessions, 90-minute weekly‎) and 2-control (n=10).The PMS Screening Tool (PSST) and Emotion Regulation Questionnaire (ERQ) before and after treatment were filled out by participant. The SPSS software and P<0.05 considered for data analysis and as significant levels respectively. Results: The study sample was 32 girls adolescents with PMS (mean age intervention and control were 16.30±2.02 and 16.40±1.6, P=0.915). The score of two questionnaires, PSST (symptom, effect) and ERQ (cognitive reappraisal, suppression) between two groups in before treatment were the same. After intervention the change of variable symptom (-1.05 vs -0.02, P<0.001), effect (-0.53 vs -0.04, P<0.001), cognitive reappraisal (0.67 vs 0.02, P<0.001) and suppression (-0.64 vs -0.07, P<0.001) were significant between two groups. Conclusion: TTP is an effective technique for controlling clinical symptoms and emotion regulation in girl’s adolescents with PMS. https://ijph.tums.ac.ir/index.php/ijph/article/view/23576 https://ijph.tums.ac.ir/index.php/ijph/article/download/23576/7634

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1389 1399 EN Tahereh Mokhtaryan Gilani Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sci-ences, Tehran, Iran Nourossadat Kariman Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran Hamid Sharif Nia Amol School of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran Mahbobeh Ahmadi Doulabi Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran Malihe Nasiri Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran Tayebeh Mokhtaryan Gilani Department of Psychology, Kharazmi University, Tehran, Iran 2020 10 11 2021 02 06 Background: It is necessary to study the predictors of life quality in the early postpartum period. Early diagnosis, timely care and intervention can improve the health of mother and baby. We aimed to evaluate the predictors of the quality of life in the postpartum period. Methods: This cross-sectional study was conducted on 407 eligible women aged 18 to 47 yr, in the postpartum period, selected from clinics affiliated with Shahid Beheshti University of Medical Sciences, Tehran, Tehran, Iran in 2018. Data were collected using a demographic and obstetric questionnaire and Maternal Postpartum Quality of Life (MAPP-QOL) with Cronbach's alpha coefficients of 0.96 to assess personal details and postpartum quality of life. Data analyzed using SPSS. Linear regression analysis was performed to examine the relationship between maternal predictors and quality of life in the postpartum period. Results: The postpartum quality of life had a significant relationship with income status (P<0.001), Number of Children (P=0.031), mother's education(P=0.009) and maternal complications (P<0.001). Conclusion: This study confirmed the relationship between maternal predictors and the postpartum quality of life. It could facilitate clinicians and educators to improve the quality of life for postpartum women.   https://ijph.tums.ac.ir/index.php/ijph/article/view/22478 https://ijph.tums.ac.ir/index.php/ijph/article/download/22478/7635

Tehran University of Medical Sciences https://ijph.tums.ac.ir/index.php/ijph/article/view/24829 https://ijph.tums.ac.ir/index.php/ijph/article/download/24829/7449

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 12 2021 11 30 2584 2592 Neriman İnanç Department of Nutrition and Dietetics, Faculty of Health Sciences, Nuh Naci Yazgan University, 38170, Kayseri, Turkey Yağmur Yaşar Fırat Department of Nutrition and Dietetics, Faculty of Health Sciences, Erciyes University, 38039, Kayseri, Turkey Eda Başmısırlı Department of Nutrition and Dietetics, Faculty of Health Sciences, Nuh Naci Yazgan University, 38170, Kayseri, Turkey Aslı Gizem Çapar Department of Nutrition and Dietetics, Faculty of Health Sciences, Nuh Naci Yazgan University, 38170, Kayseri, Turkey 2020 01 08 2020 08 20 Background: We aimed to determine the nutrient intake of Crohn’s patients and to expose its relationship with Crohn’s Activity Index (CDAI), Subjective Global Assessment (SGA) and Body Mass Index (BMI). Methods: This randomized controlled trial was conducted on patients enrolled in the Gastroenterology Polyclinic of a University Medical Faculty Hospital, Kayseri, Turkey in 2017. Two groups were included in this study: Crohn’s Group (n = 100) and Control (n = 89). Crohn’s Disease Activity Index was used to detect disease activity. Malnutrition risk was determined by the SGA and daily energy and nutrient intakes were calculated. Results: There was a significant relationship between SGA and both CDAI and BMI (P<0.001, P=0.008, respectively). Daily energy, carbohydrate, monosaccharide, starch, sucrose, fructose, poly-u