Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 10 2022 10 04 2149 2158 Zijian Pan 1. National Center for Birth Defect Monitoring, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan, China 2. West China Hospital of Stomatology, and State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, Si-chuan, China Tong Zhu 1. National Center for Birth Defect Monitoring, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan, China 2. West China Hospital of Stomatology, and State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, Si-chuan, China Jun Zhu 1. National Center for Birth Defect Monitoring, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan, China 2. Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital , Chengdu 610041, Sichuan, China Nannan Zhang 1. National Center for Birth Defect Monitoring, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan, China 2. Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital , Chengdu 610041, Sichuan, China 2021 09 18 2022 03 17 Background: The association between congenital heart defects (CHDs) and selenium (Se) is still unclear. We aimed to systematically review and quantitative analyze the potential relationship between maternal Se exposure and CHDs in the offspring. Methods: PubMed, Embase, Web of Science and Scopus databases were searched from inception up to August 2021 for relevant studies. Methodological quality of the studies was assessed through Newcastle-Ottawa scale. The Standard mean difference (SMD) and corresponding 95% confidence interval (CI) were calculated to compare maternal Se levels between CHDs groups and control groups using a random-effects model. Results: Four articles covering five studies were included in the systematic review, and three articles covering four studies were included in the meta-analysis. One study measured Se concentrations in maternal hair and found a positive correlation between high concentrations and increased risk of CHDs in offspring. However, one study on cord blood, and one on whole blood illustrated that Se exposure was associated with decreased risk of CHDs. There was no significant association found between serum Se levels and CHDs in two studies. Pooled results showed decreased Se levels in the circulation of mothers with CHDs offspring (SMD = -108.27, 95% CI: -192.72, -23.82), with statistically significant heterogeneity (I2 = 99.8%, P < 0.001) but not in hair, as compared with controls. Conclusion: Low maternal Se status may be associated with increased risk of CHDs in offspring. However, further larger-scale studies with strict and consistent design methods are still required to investigate this issue. https://ijph.tums.ac.ir/index.php/ijph/article/view/26315 https://ijph.tums.ac.ir/index.php/ijph/article/download/26315/7733

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 10 2022 10 04 2159 2170 Ali Mohammad Mosadeghrad Department of Health Management & Economics, Health Information Management Research Center, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Ebrahim Jaafaripooyan Department of Health Management & Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mahmoud Zamandi Department of Health Management & Economics, Health Information Management Research Center, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2020 09 25 2021 06 24 Background: Economic evaluation is used for the optimal allocation of resources in the health sector. While a large number of economic evaluation studies have been conducted, there is less critical review of these studies. We critically examined the economic evaluation studies of preventive health interventions. Methods: The study was carried out using critical review method. Seven databases (i.e., PubMed, Cochrane Database of Systematic Reviews, Web of Science, Science Direct, Scopus, Springer Link, and Elsevier) were searched to find articles on economic evaluation of health interventions published from 1985 to 2018. In addition, the references of retrieved studies were hand screened for articles that were not indexed in these databases. Finally, 206 articles, including 33 cost- benefit analysis, 146 cost- effectiveness analysis, and 27 cost- utility analysis were included in this study. These studies were critically evaluated using a checklist of 11 criteria. Results: Only 20% of the studies met all the methodological criteria of health economic evaluation. The cost perspective, costs type, cost data source, and cost measurement were not explained and discussed in 17%, 20%, 5%, and 33% of studies respectively. Outcome data sources and outcome valuation method were only mentioned in 53% and 69% of studies. The sensitivity analysis and results’ generalizability were not reported in 16% and 46% of studies. Conclusion: The quality of economic evaluation studies is low, and it can be misleading if resource allocation decisions are made using this evidence. Authors should use valid protocols to conduct and report economic evaluation studies, and journals’ editors should use valid checklists to evaluate these articles.   https://ijph.tums.ac.ir/index.php/ijph/article/view/22316 https://ijph.tums.ac.ir/index.php/ijph/article/download/22316/7734

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 10 2022 10 04 2171 2180 Jing Yuan Emergency Department, Luodian Hospital, Baoshan District of Shanghai, Shanghai, China Sheng-Fang Lu Emergency Department, Luodian Hospital, Baoshan District of Shanghai, Shanghai, China Ping Xu Emergency Department, Luodian Hospital, Baoshan District of Shanghai, Shanghai, China Yan-Li Niu Endocrinology Department, Luodian Hospital, Baoshan District of Shanghai, Shanghai, China 2021 05 05 2021 08 16 Background: Dexmedetomidine (Dex), as a new and highly selective α2 adrenergic receptor agonist, has been widely used in mechanically ventilated patients. In the present study, we used meta-analysis to study the effect of Dex on the prognosis of mechanically ventilated patients with sepsis. Methods: We searched PubMed, Cochrane clinical trial, EMBASE, Web of Science, and Chinese biomedical literature database to analyze relevant literature published from January 2000 to January 2021. We conducted the quality evaluation and data extraction for studies that met the inclusion criteria. RevMan 5.3 software was used to perform a meta-analysis of the 28-day mortality, hospital mortality, the length of ICU stay, and other adverse indicators. Results: Ten randomized controlled trials (RCTs) that met the inclusion criteria were finally included, including 9 RCTs in English and one in Chinese, with a total of 892 patients. Our meta-analysis results found that in mechanically ventilated patients with sepsis, Dex could significantly reduce the length of ICU stay (P=0.02), but did not reduce the patients' 28-day mortality (P=0.06), hospital mortality (P=0.17) and ventilator-free days (P=0.33). Furthermore, our meta-analysis results also found that Dex had no significant effect on the respiratory rate (P=0.53), heart rate (P=0.02), mean arterial pressure (P=0.63), the level of creatinine (P=0.82) and continuous renal replacement therapy (P=0.39) in mechanically ventilated patients with sepsis. Conclusion: In mechanically ventilated patients with sepsis, Dex can reduce the length of ICU stay, but which cannot reduce the 28-day mortality, hospital mortality, and ventilator-free days.   https://ijph.tums.ac.ir/index.php/ijph/article/view/24819 https://ijph.tums.ac.ir/index.php/ijph/article/download/24819/7735

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 10 2022 10 04 2181 2193 SasidharanPillai Sabeena Clinical Virology, Allure Residency, Near the British School, Kathmandu, Nepal Nagaraja Ravishankar Department of Biostatistics, Vallabhbhai Patel Chest Institute, University of Delhi, New Delhi, India 2021 09 17 2021 11 02 Background: Horizontal transmission of hepatitis B virus (HBV) is a significant transmission route in households, among contact sport athletes and institutionalized individuals. Children often are infected by non-sexual close contacts with an increased tendency to become chronic carriers. Hence, the awareness about various high-risk behaviours leading to horizontal transmission in the community is essential. A systematic review and meta-analysis was carried out to assess quantitatively the pooled prevalence of horizontally transmitted HBV infection globally. Methods: The study was started after ruling out registered or ongoing systematic reviews related to this topic in the PROSPERO database. The study protocol was documented in PROSPERO with a registration number CRD42021235165. We searched electronic databases for published articles in English between 1981 and April 2021 reporting horizontal modes of hepatitis B transmission among unvaccinated contacts. Meta-analysis was carried out in STATA version 13.0 (College Station, Texas 77,845 USA). The forest plots were constructed using metaprop package in STATA. Results: Forty-one studies were systematically reviewed and 15 studies were qualified for the meta-analysis, including 1619 hepatitis B cases and 4869 contacts. The overall pooled prevalence of horizontally transmitted HBV infection among the contacts was 38% (95% CI 30%-46%). The pooled prevalence among 3,912 household contacts from nine qualified studies was estimated as 44% (95% CI 35%-54%). The pooled prevalence rates among institutionalized individuals and contact sport athletes were 30% (95% CI 23%-37%) and 18% (95% CI 5%-32%), respectively.  Conclusion: The likelihood of horizontal transmission of HBV is greater among household contacts of chronic carriers of HBV and institutionalized individuals. https://ijph.tums.ac.ir/index.php/ijph/article/view/26307 https://ijph.tums.ac.ir/index.php/ijph/article/download/26307/7736

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 10 2022 10 04 2194 2206 Mohammad-Javad Khosousi Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran Fariborz Mansour-Ghanaei Caspian Digestive Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran 2. GI Cancer Screening and Prevention Research Center, Guilan University of Medical Sciences, Rasht, Iran Forough Heidarzad Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran Farahnaz Joukar Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran Saman Maroufizadeh Department of Biostatistics, School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran Elham Abdzadeh Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran Hamed Delam Student Research Committee, Larestan University of Medical Sciences, Larestan, Iran Ehsan Amini-Salehi Student Research Committee, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Morteza Arab-Zozani Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran Siavash Falahatkar Urology Research Center, Guilan University of Medical Sciences, Rasht, Iran Ardalan Akhavan Urology Research Center, Guilan University of Medical Sciences, Rasht, Iran Soheil Hassanipour GI Cancer Screening and Prevention Research Center, Guilan University of Medical Sciences, Rasht, Iran 2021 05 18 2021 10 18 Background: Hematuria is one of the most common symptoms in nephrology and urology. Due to the lack of extensive meta-analysis studies on the epidemiology of hematuria in Iran, this study was conducted to determine the epidemiological status of hematuria in Iran. Methods: In Sep 2020, researchers studied six international databases such as PubMed, ISI/WOS, ProQuest, Embase, Scopus, and Google Scholar for English papers and Iranian databases (SID and MagIran) for Persian papers. Joanna Briggs Institute (JBI) checklist was used to review and control the quality of articles. Heterogeneity between studies was assessed by Cochran's test and its composition using I2 statistics. Results: After several screening phase, the number of 25 article included to the final analysis. The prevalence of hematuria in the general population and children, in Iran were estimated at 16.4% (95% CI, - 0.05-37.9) and 1.6% (95% CI, 0.9-2.3) respectively. The odds ratio (OR) of women to men in the prevalence of hematuria in the general population 1.74, 95% CI: 1.20-2.52, P=0.003, patients with beta-thalassemia major 2.02, 95% CI: 1.11-3.65, P=0.020, children 2.61, 95% CI: 1.19-5.71, P=0.016, the elderly 1.50, 95% CI: 1.15-1.94, P=0.002, and taxi drivers 3.73, 95% CI: 2.58-5.38, P<0.001 was obtained. Conclusion: The prevalence of hematuria in the general population is relatively high. Hematuria is a good predictor for detecting of bladder cancer and Idiopathic hypercalciuria and the physician should attention to microscopic hematuria. https://ijph.tums.ac.ir/index.php/ijph/article/view/24982 https://ijph.tums.ac.ir/index.php/ijph/article/download/24982/7737

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 10 2022 10 04 2207 2220 EN Mousa Ghelichi-Ghojogh PhD Student in Epidemilogy, Department of Epidemilogy, Shiraz University of Medical Sciences, Iran. Abdolhalim Rajabi Assistant of Professor of Epidemiology, Department of Health Management and Social Development Research Center, Faculty of Health, Golestan University of Medical Sciences, Gorgan. Iran. Fateme Mohammadizadeh Student Research Commitee, Shiraz University of Medical Sciences, Shiraz, Iran. Layla Shojaie Division of GI/Liver, Department of Medicine, Keck school of Medicine, University of Southern California, Los Angeles, CA. USA. Mouhebat Vali PhD Student in Epidemiology, Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran. Sima Afrashteh PhD Student in Epidemiology, Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran. Soheil Hassanipour Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran. Hossein-Ali Nikbakht Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciencesjoint under static conditions, as well as joint motion ranges and static balance in girls aged 14 years. Methods: The study included 40 girls aged 14, who attended Gymnasium No. 2 in Cracow (Poland). The research was conducted in October 2020. Postural stability was examined with the use of the YBT. The measurements of muscle strength and knee joint extensor and flexor resistance to fatigue during an isometric contraction were performed in a standard position on the test bench. The measurements of lower extremity joint range of motion were performed in accordance with the SFTR methodology. Static balance was assessed with the use of the modified FBT. Results: The factor structure obtained for both lower extremities has satisfactorily explained the common variance (about 70%) and showed slight differences between the left and right extremities. Conclusion: The factor structure in the group of examined girls suggests a highly hybrid nature of the Y-Balance Test with a wide spectrum of biomechanical variables that have little influence on the measurement results.   https://ijph.tums.ac.ir/index.php/ijph/article/view/26718 https://ijph.tums.ac.ir/index.php/ijph/article/download/26718/7931

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 07 892 902 Jae-hak Do Department of Korean Language and Literature, Kyonggi University, Suwon, Korea Sam-hun Park Asia Contents Institute, Konkuk University, Seoul, Korea 2023 02 03 2023 05 07 Background: Previous research dealt with the concept of ‘hygiene’ in Korea, mainly regarding the modern transition summarized as ‘from regimen to hygiene’, has been based on qualitative research methods. However, because modern Korean language material had been constructed as a corpus with a considerable size, a quantitative approach based on language material has become possible. Through this, the provision of a new implication point can be received. Methods: The Corpus of Modern Korean Magazines, which is a morph-tagged corpus constructed based on 20 kinds of original texts of modern magazines in Korea, was utilized. In this corpus, a list of the co-occurred words of ‘wisaeng [hygiene], yangsaeang [regimen], geongang [health], and cheonggyeol [cleanliness]’, importantly related to the concept of ‘modern hygiene’ and the strength of co-occurrence that was calculated with the t-score, were extracted and analyzed.  Results: Through a quantitative analysis of the corpus base, it was confirmed that the number of the co-occurred words of ‘wisaeng [hygiene]’ decreases and the strength of the co-occurrence gets low.  In contrast, the number of the co-occurred words of ‘geongang [health]’ increases and the strength of the co-occurred words becomes heightened.  Conclusion: Regarding the change after ‘from regimen to hygiene’, an analysis based on the corpus has been attempted. Through the quantitative data, the conversion into ‘from hygiene to health’ was confirmed. Research with such a method proves the need and the feasibility of quantitative research that supplements the previous qualitative analysis.   https://ijph.tums.ac.ir/index.php/ijph/article/view/31130 https://ijph.tums.ac.ir/index.php/ijph/article/download/31130/7947

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 1095 1096 Sung-Bum Ju Department of Physical Education, Busan National University of Education, Busan, South Korea 2020 12 08 2021 01 11 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/23100 https://ijph.tums.ac.ir/index.php/ijph/article/download/23100/7945

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 978 985 Berta Schulz-Bañares Department of Pharmacy, School of Pharmacy, University of Concepcion, Concepcion, Chile Carla González-Norambuena Central Pharmacy, Hospital Las Higueras, Talcahuano, Chile Claudio Muller-Ramirez Department of Pharmacy, School of Pharmacy, University of Concepcion, Concepcion, Chile 2022 09 01 2023 01 09 Background: Poisonings is a preventable public health problem that globally affects the population. We aimed to characterize drug-related acute poisonings occurred in Chile between the years of 2016 and 2020. Methods: A retrospective study of poisonings among hospitalized patients was carried out. Data were obtained from the Medical Outcome Statistical Report database. Inclusion criteria were cases of patients admitted into either public or private healthcare settings with diagnosis of drug-related poisoning according to the WHO ICD-10 codes T30-T50. Statistical analyses were run to establish either significant associations or differences between variables selected in the study. Results: Overall, 12,975 poisonings were identified during the 2016-2020 period. These events corresponded to 0.16% of all national hospital admissions in the study period. Women represented 71.1% of the cases. 76.7% of events were related to intentional poisonings while 7.3% and 16% were accidental and undetermined poisonings respectively. 44.6% of accidental and intentional poisonings occurred at the age of 18-29 yr old. Benzodiazepines (22.8%), antidepressants (11.2%), and acetaminophen (5.1) were the most common drugs associated with poisonings. Average length of hospitalization was between 3.3 and 8.2 days. 0.6% of poisonings resulted in deaths.     Conclusion: Poisonings were characterized by patients’ sex and age, circumstance of exposure, length of hospitalization, and outcome. Poisoning rates were stable along the years with a slight decrease in 2020. Intentional poisonings among young women and men were more common. Most of the cases had favorable outcome for patients.   https://ijph.tums.ac.ir/index.php/ijph/article/view/29695 https://ijph.tums.ac.ir/index.php/ijph/article/download/29695/7932

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 07 903 912 Liming Zhao Department of Vascular Surgery, Liu Zhou People’s Hospital, Guangxi, 545006, China Ying Liu Department of Endocrinology, Affiliated Hospital of Youjiang Medical University for Nationalities, Guangxi, China Ziting Cao Department of Vascular Surgery, Liu Zhou People’s Hospital, Guangxi, 545006, China Jun Wang Department of Vascular Surgery, Liu Zhou People’s Hospital, Guangxi, 545006, China Xin Huo Department of Vascular Surgery, Liu Zhou People’s Hospital, Guangxi, 545006, China 2022 11 07 2023 01 22 Background: Proprotein convertase subtilisin / Kexin type 9 (PCSK9) inhibitors are efficacious lipid-lowering agents. This drug is related to improving the prognosis of patients with cardiovascular disease (CVD). The purpose of this meta-analysis was to systematically analyze the safety and efficacy of PCSK9 inhibitors in all published randomized controlled trials (RCTs). Methods: As of October 25, 2021, we searched PubMed, EMBASE, MEDLINE, Cochrane Library and web of science. Results: From 684 articles, we included 11 trials for meta-analysis, including 52511 participants (26938 in the PCSK9 inhibitor group and 25573 in the control group). In terms of effectiveness, PCSK9 inhibitors reduced the risk of major adverse cardiovascular events(MACE) (OR=0.89, 95% Cl: 0.83-0.95, P=0.0009), but did not significantly reduce the risk of cardiovascular death (OR=0.95, 95% Cl: 0.84-1.07, P=0.38) or all-cause death (OR=0.93, 95% Cl: 0.85-1.03, P=0.18); In terms of safety, PCSK9 did not increase the risk of treatment-emergent adverse events (TEAE)(OR=0.98, 95% Cl: 0.94-1.02, P=0.28). Conclusion: PCSK9 inhibitors can significantly reduce the risk of MACE in patients with high cardiovascular risk, which is well tolerated, but the impact on the risk of death is unclear.   https://ijph.tums.ac.ir/index.php/ijph/article/view/30305 https://ijph.tums.ac.ir/index.php/ijph/article/download/30305/7925

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 1097 1098 Mahdi Mohammadian Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran Abdollah Mohammadian-Hafshejani Modeling in Health Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran 2021 12 10 2022 01 16 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/27135 https://ijph.tums.ac.ir/index.php/ijph/article/download/27135/7946

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 986 994 EN Xiuli Hu Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Miao Qi Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Ping Yuan Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Guojia Qi Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Xiahong Li Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Yanna Zhou Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China Xiuquan Shi Department of Epidemiology and Health Statistics, School of Public Health, Zunyi Medical University, Zunyi, Guizhou, China 2021 09 27 2022 02 23 Background: We aimed to analyze the differences and changing trends of mortality of Injury and Poisoning (IP) between urban and rural areas and gender in China to find out the influencing factors and to propose improvement measures. Methods: IP mortality, population, economy, medical and health information data came from the official website of the National Bureau of Statistics, and basic data on education level came from the Chinese Ministry of Education. Then the differences of the mortality of IP were compared between different areas and gender in China from 2009 to 2019, and the relationships between the mortality changes of IP and education level, GDP per capita, the numbers of practicing physicians, health institutions and urbanization rate were also explored by establishing a ridge regression model. Results: The mortality of IP in rural areas was significantly higher than that of urban areas, and in male was higher than that of female (both P<0.001). Primary school graduates, GDP per capita, the number of practicing physicians, health institutions and urbanization rate had strong correlations (rmin=-0.622) with the mortality of IP. Ridge regression model showed that there was a quantitative relationship between primary school graduates, GDP per capita, the number of practising physicians, health institutions, urbanization rate and the mortality of IP in China. Conclusion: As the difference of working nature, economic development imbalance, psychological and gender, the mortality of IP was significantly different, so the state should take more effective measures to develop the urban and rural areas balanced, and reduce the IP risk in some particular occupations.   https://ijph.tums.ac.ir/index.php/ijph/article/view/26408 https://ijph.tums.ac.ir/index.php/ijph/article/download/26408/7933

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 07 913 923 Niloofar Mohammadzadeh Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran Meysam Rahmani Katigari Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran Rahil Hosseini Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran Shahrbanoo PahlevanyNejad Health Information Technology Department, School of Allied Medical Sciences, Semnan University of Medical Sciences, Semnan, Iran 2022 01 19 2022 09 10 Background: This study was conducted to classify the types of evaluation methods in clinical health technologies based on a systematic review method. Methods: An electronic search was conducted in three scientific databases including Scopus, PubMed and ISI. The search strategy was performed in Jul to Nov 2021 and based on the three main concepts of "evaluation", "technology", "health. This search has been restricted to 10 years (2011-2021). Moreover, it only was limited to English and papers published in journals and conferences proceeding. Results: Overall, 8149 references were identified for title and abstract screening. Full text screening was performed for 2674 articles, with 174 meeting the criteria for study inclusion. Conclusion: Most of the technologies evaluated in these articles were associated with PC-based systems (N=107), and there have been fewer mobile apps (N=67). Most of used technologies were with goals of treatment (43%, N=74) and education (26%, N=45). Among all the methods, the most and the least used methods were usability (66%, N=115) and qualitative (1%, N=2) method, respectively. The most method for health clinical technologies is usability method especially in telemedicine field.   https://ijph.tums.ac.ir/index.php/ijph/article/view/27551 https://ijph.tums.ac.ir/index.php/ijph/article/download/27551/7926

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 995 1007 EN Yunying Cai Department of Endocrinology and Metabolism, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, China Ben Niu Department of Endocrinology and Metabolism, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, China Jie Gao Department of Endocrinology and Metabolism, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, China Heng Su Department of Endocrinology and Metabolism, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650032, China 2022 12 19 2023 01 22 Background: Cuproptosis-related long non-coding RNA (lncRNA) disease is associated with the development and progression of tumors. We aimed to investigate the prediction of cuproptosis-related lncRNA on the prognosis and immunotherapy of patients with thyroid carcinoma (THCA). Methods: The thyroid cancer-associated expression data and lnc RNAs data were downloaded from The Cancer Genome Atlas (TCGA) and Ensembl database. The prognostic model of cuproptosis-related lncRNAs was successfully constructed through Lasso regression analysis and Cox regression analysis. Then, the prognostic value of prognostic model of cuproptosis-related lncRNAs was tested through the survival analysis, ROC curves and nomographic charts. Finally, the prognostic model of cuproptosis-related lncRNAs associated with immunity and mutational load of tumors was analyzed, and potential targeted drugs for THCA were predicted. Results: A cuproptosis-related lncRNA model of THCA (AC026100.1, AF235103.3, LNCSRLR) was successfully constructed, which has an independent prognostic value. Moreover, the cuproptosis-related lncRNA model was associated with immune signatures and mutational load in most tumors, showing its high correlation with the sensitivity of targeted drugs such as 5-Fluorouracil, Bleomycin, Rapamycin and Sunitinib. Conclusion: The cuproptosis-related lncRNA model of THCA has promising applications in the treatment and prognosis of THCA. https://ijph.tums.ac.ir/index.php/ijph/article/view/30706 https://ijph.tums.ac.ir/index.php/ijph/article/download/30706/7934

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 07 924 936 Nilay Rezaei-Tavabe Department of Epidemiology and Biostatistics, School of Public Health, Shahrekord University of Medical Sciences, Shahrekord, Iran Soleiman Kheiri Department of Epidemiology and Biostatistics, School of Public Health, Shahrekord University of Medical Sciences, Shahrekord, Iran Masoumeh Sadat Mousavi Department of Epidemiology and Biostatistics, School of Public Health, Shahrekord University of Medical Sciences, Shahrekord, Iran Abdollah Mohammadian-Hafshejani Modeling in Health Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran 2022 02 09 2022 10 25 Background: In recent years, various studies have been conducted to investigate the role of the influenza vaccine in reducing the risk of hospitalization and mortality; however, the results of these studies are clearly contradictory. Accordingly, we aimed to investigate the effect of monovalent flu vaccines on the risk of hospitalization and all-cause mortality. Methods: This study was a systematic review and meta-analysis of Randomized Clinical Trial (RCT) studies published in databases (Web of Science (ISI), Scopus, PubMed, Cochrane, Science Direct, Google Scholar) from 1980 to Dec 2022. All analyzes were performed by Stata15 statistical software and the significance level in this study was considered 0.05. Results: In the initial search, 375 articles were retrieved which, considering the study criteria, finally 8 RCT were included in the meta-analysis of the effects of monovalent Flu vaccine on the risk of hospitalization, and 10 RCT on the risk of all-cause mortality. Based on the results of meta-analysis, the overall Odds Ratio (OR) of hospitalization is equal to 0.71 (95% CI: 0.56-0.90; P <0.001) and the overall OR of all-cause mortality is equal to 0.82 (95% CI: 0.68-0.98; P=0.033). There was no publication bias in the study of the effect of monovalent flu vaccine on the risk of hospitalization and all-cause mortality Conclusion: Getting the flu vaccine can reduce the risk of hospitalization by 29% and the risk of overall death by 18%. Therefore, it may be promising to receive this vaccine as a preventive intervention for deaths and hospitalizations. https://ijph.tums.ac.ir/index.php/ijph/article/view/27811 https://ijph.tums.ac.ir/index.php/ijph/article/download/27811/7927

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 52 5 2023 05 08 1008 1018 Chongjun Zhao School of Foreign Languages, Xianyang Normal University, Xianyang, China Jing Li Department of Physical Education, Xianyang Normal University, Xianyang, China Seung-Yong Kim Department of Leisure Sports, Dong Seoul University, Gyeonggi-do, Republic of Korea 2023 03 03 Effect of Narrative Therapy-based Group Psychological Counseling on Internet Addiction among Adolescents 1331 1338 Yingying Gong Department of Physical Education, Physical Education Institute, Hunan City University, Yiyang, China Ning Gong Department of Physical Education, Physical Education Institute, Hunan City University, Yiyang, China Zhihui Zhang Department of Physical Education, Physical Education Institute, Hunan City University, Yiyang, China Yang He Hunan City University Haiou Tang Department of Physical Education, Physical Education Institute, Hunan City University, Yiyang, China 2022 04 05 2022 06 08 Background: There are a large number of psychological problems caused by Internet addiction. We aimed to explore the intervention effect of narrative therapy in combination with Pilates exercise on Internet addiction among adolescents. Method: From July 2021 to October 2021, 42 adolescents with Internet addiction selected from four communities in Yiyang City of China were randomly divided into the intervention and control groups with 21 members in each group. The intervention group participated in the intervention of narrative therapy in combination with Pilates exercise eight times, whereas the control group did not receive any intervention. The 12-item General Health Questionnaire, Self-rating Young’s Diagnostic Questionnaire of Internet Addiction, and Positive Affect Subscale were used to measure the psychological indexes of the adolescents before and after the intervention. Results: Compared with those in the control group, the adolescents in the intervention group had an obvious decrease in the degree of Internet addiction with a statistically significant difference before and after the intervention (P < 0.001). After the intervention, the intervention group had significantly higher mental health scores and significantly lower scores for anxiety, depression, social dysfunction, and loss of interest than the control group. After the intervention, the intervention group showed an obvious increase in the score for positive affect with a statistically significant difference before and after the intervention (P < 0.001). Conclusion: The intervention method proposed in this study could effectively solve the problem of Internet addiction among adolescents. https://ijph.tums.ac.ir/index.php/ijph/article/view/28344 https://ijph.tums.ac.ir/index.php/ijph/article/download/28344/7628

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1339 1347 Yunus Beyhan Department of Medical Parasitology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey Cuneyt Albayrak Department of Medical Parasitology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey Irem Guven Department of Medical Parasitology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey 2020 11 23 2021 02 06 Background: Cytokines are protein substances involved in immune response and inflammation regulation, cell growth, tissue repair and natural and adaptive immunity events such as hematopoiesis. Changes in Th1 and Th2 immune responses provide information on the clinical presentation, pathology and diagnosis of diseases. Methods: This study was conducted on 142 patients, aged 18-95 yr and applied to Parasitology Laboratory of Van Yuzuncu Yil Hospital between Aug 2018 and May 2019. Fifty-one of the patients were serologically diagnosed with CE, 53 with a diagnosis of fascioliasis, and 38 as the control group. Serum samples were taken from patients and levels of IL-4, IL-10, TNF α and IFN γ parameters were investigated by ELISA method. Results were evaluated by spectrophotometer and observed which immunologic parameters increased in which infections. Cytokine results were also evaluated according to patient age groups and genders. Chi-square and/or Fisher's exact test were used to evaluate the results. IL-4 response was detected in 50.9%; IL-10 in 44.2%; TNF-α in 43.3% and IFN-γ in 43.3% of CE seropositive patients. Results: IL-4, IL-10, TNF-α and IFN-responses detected in 50.9%, 44.2%, 43.3% and 43.3% of CE patients, and in 43%, 39.2%, 34.4% and 40.6% of fascioliasis patients, respectively. The presence of Th1 and Th2 responses were detected in both infections. There was a significant relationship between fascioliasis and IL-4 response and between CE and IL-4, IL-10 and TNF-α responses (P≤.05). Conclusion: These cytokine levels may provide information about the immune response to infections, and may be useful for early detection of disease and recurrence and monitoring of treatment. https://ijph.tums.ac.ir/index.php/ijph/article/view/22965 https://ijph.tums.ac.ir/index.php/ijph/article/download/22965/7629

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1348 1354 EN Negin Badrooj Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran Seyed Ali Keshavarz Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran Curtis Tilves Department of Epidemiology, School of Public Health, Johns Hopkins University Bloomberg, Baltimore, MD, USA Mir Saeed Yekaninejad Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Sara Pooyan Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran Nasim Ghodoosi Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran Khadijeh Mirzaei Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran 2020 07 13 2021 04 13 Background: The increasing trend of obesity prevalence is a serious health warning for people worldwide. Evaluation of anthropometric measures is essential for explaining individual’s health status. Studies have investigated the effect of diet on inflammation. Empirical Dietary Inflammatory Pattern (EDIP) was recently developed to empirically create a score for overall inflammatory potential of diet. This study aimed to investigate the relationship between EDIP with anthropometric measures in women with overweight and obesity. Methods: In a cross-sectional study, the EDIP score was calculated for 301 participants from their food frequency questionnaire, who referred to health centers in Tehran, Iran in 2018. Anthropometric measures was assessed through multi-frequency bioelectrical impedance analyzer. Results: 49% (95% CI: 40.8 - 57.2) had positive EDIP score. A significant relationship was found between EDIP quartiles with weight (P=0.004), BMI (P=0.012), FM (P=0.013), WC (P=0.003) and WHR (P=0.031). Those individuals in the lowest group of EDIP score had significantly lower weight, Body Mass Index, Fat Mass, Waist Circumference and Waist to Hip Ratio, compared to those with highest inflammation score. Conclusion: A significant relationship was found between EDIP with anthropometric measures in women with overweight and obesity, supporting the hypothesis that an anti-inflammatory diet is associated with decreasing trend of weight, Body Mass Index, Fat Mass, Waist Circumference and Waist to Hip Ratio.   https://ijph.tums.ac.ir/index.php/ijph/article/view/21464 https://ijph.tums.ac.ir/index.php/ijph/article/download/21464/7630

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 51 6 2022 06 08 1355 1363 Nasirudin Javidi 1. Behavioral Sciences Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran 2. Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran Mostafa Ghanei Chemical Injuries Research Center, Systems Biology and Poisoning Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran Khodabaksh Ahmadi Behavioral Sciences Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran Mohammad Javad Ahmadizadeh Behavioral Sciences Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran Abbas Ebadi Behavioral Sciences Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran AND Faculty of Nursing, Baqiyatallah University of Medical Sciences, Tehran, Iran 2020 12 22 2021 04 03 Background: Quality of life is determined by the lifestyle of individuals. If people have a healthy lifestyle, then they have a higher quality of life. What makes a person's lifestyle is the way he thinks. Therefore, if the thinking is healthy, the person's lifestyle will be healthy, and if the thinking is unhealthy, the person's lifestyle will also be damaged, which will reduce the quality of life. Methods: The research method was mixed method in two quantitative and qualitative phases. The research method in the qualitative phase was customary qualitative content analysis, in which the data analysis process was based on the approach of Granheim and Ladman. In the quantitative phase, the psychometric properties of the research scale were measured. This research was conducted from 2016 to 2021 in Iran. The statistical population in the qualitative section was all scientific texts in the form of articles, books and dissertations that were extracted from scientific databases such as ScienceDirect, PubMed, Elsevier, Ebsco, Sid, Magiran. Results: Indicators of intellectual thinking have been mentioned as research results, which are the main components of the new model of thinking. Moreover, the level of thinking was mentioned and Cognitive distortions, cognitive bias, and perceptual errors were mentioned as sources of harm and error. Conclusion: Intellectual thinking has been mentioned as healthy thinking, which is the main factor of a health promotion lifestyle because healthy lifestyle improves the quality of life of people, which is one of the indicators of public health. Therefore, a higher quality of life can be achieved from the model of h/PubDate> 2555 2559 Na Zhang 1. Maternal and Child Health Hospital of Hubei Province, Wuhan 430070, China 2. Women and Children's Hospital of Hubei Province, Wuhan 430070, China Ying Wang 1. Maternal and Child Health Hospital of Hubei Province, Wuhan 430070, China 2. Women and Children's Hospital of Hubei Province, Wuhan 430070, China Li Zhang 1. Maternal and Child Health Hospital of Hubei Province, Wuhan 430070, China 2. Women and Children's Hospital of Hubei Province, Wuhan 430070, China Chanyun Xiao 1. Maternal and Child Health Hospital of Hubei Province, Wuhan 430070, China 2. Women and Children's Hospital of Hubei Province, Wuhan 430070, China 2021 05 21 2021 11 30 Background: To analyze the complications and outcome of mediastinal uterine pregnancy, and put forward targeted prevention and treatment measures. Methods: A total of 248 pregnant women with mediastinal uterus treated were enrolled from Jan 2015 to Dec 2018 in the Maternal and Child Health Hospital of Hubei Province, China. The data, including complications of pregnancy, gestational weeks, mode of delivery, postpartum hemorrhage, placental condition and perinatal prognosis, were collected and analyzed. Results: There were 12 cases with abnormal fetal position in the previous cesarean section. The total number of cases with abnormal fetal position was 99(49.75%). For women with abnormal fetal position during mediastinal uterine pregnancy, there was a significant increase in the incidence of placental abruption (P<0.05). The average gestational age at termination of pregnancy was 37+5weeks. There were 55 cases (22.18%) of premature and 49 cases (19.75%) of premature rupture of membranes, including 29 cases of abnormal fetal position and premature rupture of membranes, mediastinal uterus preterm birth, premature rupture of membranes (P<0.05). There were 13 cases (5.24%) of postpartum hemorrhage, natural birth without neonatal asphyxia, five cases (2.02%) of neonatal asphyxia, preterm birth, and 51 cases (20.56%) of placental adhesion. Of these, 37 cases were cesarean, 13 were spontaneous production, and 71 were fetal umbilical cord winding. Conclusion: The pregnancy induced spontaneous abortion, premature delivery, premature rupture of membranes and abnormal fetal position in mediastinal uterus are significantly higher than normal pregnancy. The complications during delivery are significantly higher than in normal pregnant women. https://ijph.tums.ac.ir/index.php/ijph/article/view/25013 https://ijph.tums.ac.ir/index.php/ijph/article/download/25013/7446

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 12 2021 11 30 2560 2566 Juan Sun Nephrology Department, The First People’s Hospital of Lianyungang, Lianyungang 222000, China Wei Cao Nephrology Department, The First People’s Hospital of Lianyungang, Lianyungang 222000, China Yang Song Nephrology Department, The First People’s Hospital of Lianyungang, Lianyungang 222000, China Chunmei Yuan Nephrology Department, The First People’s Hospital of Lianyungang, Lianyungang 222000, China 2021 04 27 2021 07 17 Background: We aimed to explore the effect of Plan, Do, Check, Act (PDCA) circulation nursing on the prevention of aneurysm after hemodialysis. Methods: A total of 139 hemodialysis patients from Oct 2018 to Jan 2020 in Nephrology Department of the First People’s Hospital of Lianyungang, China were enrolled. They were randomly divided into control group and PCDA group, including 58 patients in control group and 81 patients in PCDA group. Patients' satisfaction, blood flow in arteriovenous internal fistula and the incidence of post-dialysis vascular-related complications were statistically investigated in the two groups. Results: The satisfaction of patients in PDCA group was significantly higher than that in control group (P<0.001). In addition, when there was no statistical difference in blood flow between the two groups, the probability of complications such as internal fistula obstruction, thrombosis, infection, secondary puncture and aneurysm was lower in patients in the PDCA group, none of which occurred aneurysm. Conclusion: PDCA circulation nursing can effectively improve the quality of care and medical effect of hemodialysis patients with internal arteriovenous fistula, improve patient satisfaction and reduce the incidence of complications. https://ijph.tums.ac.ir/index.php/ijph/article/view/24725 https://ijph.tums.ac.ir/index.php/ijph/article/download/24725/7447

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 12 2021 11 30 2567 2575 Jian Wang Department of General Practice, Zhongshan Hospital, Fudan University, Shanghai, China Xiuqin Chen Injury Prevention Division, Songjiang District Center for Disease Control and Prevention, Shanghai, China Xiaoming Sun Department of General Practice, Shanghai Medical College, Fudan University, Shanghai, China Huifen Ma Injury Prevention Division, Songjiang District Center for Disease Control and Prevention, Shanghai, China Yan Yu Injury Prevention Division, Shanghai Municipal Center for Disease Control and Prevetion, Shanghai, China Chunxia Yao Injury Prevention Division, Songjiang District Center for Disease Control and Prevention, Shanghai, China Zhipeng Li Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China Limei Huang Injury Prevention Division, Songjiang District Center for Disease Control and Prevention, Shanghai, China Qi Zhao Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China 2020 07 04 2021 03 06 Background: We aimed to evaluate the predictive value of the 'Timed Up and Go' test (TUGT) for identifying fall risk in community-dwelling elderly. Methods: From Aug 2016 to Feb 2017, cluster sampling was conducted among residents aged over 60 from 15 communities in Songjiang district, Shanghai. Face-to-face questionnaire interviews and TUGT measures were conducted to collect data. Results: 6,014 participants were enrolled, with an average age 72.7±7.0 years. 637 (10.6%) elderly people had a fall experience in the past year. TUGT for the non-fall group, one-fall group and recurrent-fall group was 9.02±4.39, 10.00±5.26 and 10.78±4.51 seconds respectively (P<0.001). ROC analysis showed that the TUGT cut-off point for the elderly was 12.5 seconds and AUC was 0.573 for any-fall group and 0.613 for recurrent-fall group respectively. After adjusting for age and gender, the predictive value was not high for any-fall group (AUC=0.614) and recurrent-fall group (AUC=0.648). The TUGT cut-off point for the elderly aged below 65, 65-74, 75-84 and 85 and above was 13.52s, 12.51s, 12.51s, 12.00s, respectively. After adjustment of the confounding factors, the OR values for the risk of fall for the elderly men and women who completed TUGT longer than the cut-off point was 2.404 and 2.075 times higher than those who completed TUGT shorter than the cut-off point, respectively. Conclusion: TUGT with the cut-off score of 12.5s has limited capability in predicting fall risk in community-dwelling elderly. https://ijph.tums.ac.ir/index.php/ijph/article/view/21337 https://ijph.tums.ac.ir/index.php/ijph/article/download/21337/7448

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 12 2021 11 30 2576 2583 Yan Li Digestive Internal, The People’s Hospital of Wuhai, Wuhai, P.R. China Hailong Lei Internal Medicine-Oncology, The People’s Hospital of Wuhai, Wuhai, P.R. China Ming Zhang General Surgery, The People’s Hospital of Wuhai, Wuhai, P.R. China Guangming Wu General Surgery, The People’s Hospital of Wuhai, Wuhai, P.R. China Caiyun Guo Digestive Internal, The People’s Hospital of Wuhai, Wuhai, P.R. China Zijing Yang Digestive Internal, The People’s Hospital of Wuhai, Wuhai, P.R. China Jingting Zhang Clinical Laboratory, The People's Hospital of Wuhai, Wuhai, P.R. China Yuan Wang Clinical Laboratory, The People's Hospital of Wuhai, Wuhai, P.R. China Jianbin Zhu Digestive Internal, The People’s Hospital of Wuhai, Wuhai, P.R. China Yongzhe Du Digestive Internal, The People’s Hospital of Wuhai, Wuhai, P.R. China 2021 05 06 2021 06 21 Background: To study the molecular mechanism of cisplatin chemotherapy resistance in colorectal cancer cells and to explore the effect of miRNA in regulating the expression of glucose transporter 3 (SLC2A3) and the proliferation and migration of colon cancer cells. Methods: All samples were obtained from the People’s Hospital of Wuhai, Wuhai, China between June 2019 and June 2020. Real-time quantitative PCR (qRT-PCR) was carried out to check the expression of miR-103a in these cell lines. Western blotting and Luciferase reporter gene detection confirmed the regulation of the miR-103a/SLC2A3 axis. Western blotting detected the activation of SLC2A3, caspased-9 and -3. Results: The expression of SLC2A3 protein in colon cancer cell lines was significantly higher than that of normal colon cancer cells, while the expression of SLC2A3 miRNA showed no significant difference (P<0.05). Then, through clone formation analysis, SLC2A3 was closely related to the proliferation of human colon cancer cells. Functional recovery experiments showed that increasing the expression of miR-103a could reverse the abnormal proliferation caused by overexpression of SLC2A3. Conclusion: Overall, miR-103a can inhibit the proliferation of human colon cancer cells by targeting SLC2A3, and this result will provide a potential target for the treatment of colon cancer. https://ijph.tums.ac.ir/index.php/ijph/article/view/24829 https://ijph.tums.ac.ir/index.php/ijph/article/download/24829/7449

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 12 2021 11 30 2584 2592 Neriman İnanç Department of Nutrition and Dietetics, Faculty of Health Sciences, Nuh Naci Yazgan University, 38170, Kayseri, Turkey Yağmur Yaşar Fırat Department of Nutrition and Dietetics, Faculty of Health Sciences, Erciyes University, 38039, Kayseri, Turkey Eda Başmısırlı Department of Nutrition and Dietetics, Faculty of Health Sciences, Nuh Naci Yazgan University, 38170, Kayseri, Turkey Aslı Gizem Çapar Department of Nutrition and Dietetics, Faculty of Health Sciences, Nuh Naci Yazgan University, 38170, Kayseri, Turkey 2020 01 08 2020 08 20 Background: We aimed to determine the nutrient intake of Crohn’s patients and to expose its relationship with Crohn’s Activity Index (CDAI), Subjective Global Assessment (SGA) and Body Mass Index (BMI). Methods: This randomized controlled trial was conducted on patients enrolled in the Gastroenterology Polyclinic of a University Medical Faculty Hospital, Kayseri, Turkey in 2017. Two groups were included in this study: Crohn’s Group (n = 100) and Control (n = 89). Crohn’s Disease Activity Index was used to detect disease activity. Malnutrition risk was determined by the SGA and daily energy and nutrient intakes were calculated. Results: There was a significant relationship between SGA and both CDAI and BMI (P<0.001, P=0.008, respectively). Daily energy, carbohydrate, monosaccharide, starch, sucrose, fructose, poly-unsaturated fatty acids, omega-3 fatty acids, fiber, vitamin E and C, thiamine, niacin, pyridoxine, Mg, P, Fe, Cu, Zn intakes were significantly lower in Crohn’s Group than in Control Group. While more than 50% of the patients did not consume enough, B6, C, thiamine, niacin, folic acid, Mg, Ca and fiber, intakes of vitamin E, riboflavin, Fe, P, and Zn were adequate. Energy and nutrient  (vitamin E, thiamine, vitamin B6, mono and poly unsaturated fatty acids, saturated fatty acids, Mg, Ca, P, Zn, n-3 fatty acids and starch) intakes were negatively correlated with CDAI, but there was no relationship between these intakes and SGA. Conclusion: There was a relationship between CDAI, SGD and BMI used to determine nutritional status in patients with Crohn’s. https://ijph.tums.ac.ir/index.php/ijph/article/view/19399 https://ijph.tums.ac.ir/index.php/ijph/article/download/19399/7450

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 12 2021 11 30 2593 2598 Zeinab Barati 1. Fetal Health Research Center, Hope Generation Foundation, Tehran, Iran 2. Applied Biotechnology Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran 3. Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany Dariush Farhud 1. Farhud Genetic Clinic, Tehran, Iran 2. Department of Basic Sciences/Ethics, Iranian Academy of Medical Sciences, Tehran, Iran Uwe Nixdorff European Prevention Center, Düsseldorf, Germany Mohammadreza Mohammadhasani Applied Biotechnology Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran Maryam Eslami 1. Applied Biotechnology Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran 2. Department of Genetics, Faculty of Advanced Sciences & Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran Karim Nayerniya European Center for Personalized Medicine, Düsseldorf, Germany 2020 12 12 2021 04 14 Cardiomyopathies are heterogeneous and critical disorders of cardiovascular diseases. One of the most common inherited cardiomyopathies is DCM (dilated cardiomyopathy). Genetic disorders are found in approximately 50% of DCM cases. We aimed to describe a case of DCM in a 42-year-old woman in 2018 at Farhud Genetic Clinic, Tehran, Iran. To detect genetic involvement, Next-generation sequencing (NGS) was performed and the data were evaluated carefully. Variations in different genes coding crucial proteins in cardiac muscle structure (i.e. Titin, Obscurin, MYH6, and LAMA4) and proteins involved in channels (i.e. CAVNA1C, SCN1B and SCN5A) were detected by whole-exome sequencing (WES). In agreement with the clinical manifestations and molecular analysis, DCM was confirmed. This study provides further evidence on the diagnostic role of NGS in borderline DCM cases. It also shows the recently developed high throughput sequencing can provide clinicians with this approach to diagnosis, treatment, and prevention of such hard-to-diagnose disorders. Furthermore, this study highlights the basis of personalized medicine, namely detection of high-risk individuals by revealing some genetic variants as predictive risk factors, and initial prevention of DCM. https://ijph.tums.ac.ir/index.php/ijph/article/view/23171 https://ijph.tums.ac.ir/index.php/ijph/article/download/23171/7451

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 12 2021 12 01 2599 2600 Jung Hun Lee National Leading Research Laboratory, Department of Biological Sciences, Myongji University, Yongin, Gyeonggido 17058, Re-public of Korea Tae Yeong Kim National Leading Research Laboratory, Department of Biological Sciences, Myongji University, Yongin, Gyeonggido 17058, Re-public of Korea Sumera Kausar Malik National Leading Research Laboratory, Department of Biological Sciences, Myongji University, Yongin, Gyeonggido 17058, Re-public of Korea Jeong Ho Jeon National Leading Research Laboratory, Department of Biological Sciences, Myongji University, Yongin, Gyeonggido 17058, Re-public of Korea Young Bae Kim Biotechnology Program, North Shore Community College, 1 Ferncroft Road, Danvers, MA 01923, USA Byeong Chul Jeong National Leading Research Laboratory, Department of Biological Sciences, Myongji University, Yongin, Gyeonggido 17058, Re-public of Korea Sang Hee Lee National Leading Research Laboratory, Department of Biological Sciences, Myongji University, Yongin, Gyeonggido 17058, Re-public of Korea 2019 04 28 2019 06 25 Not Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/16989 https://ijph.tums.ac.ir/index.php/ijph/article/download/16989/7452

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 12 2021 12 01 2601 2603 Ji Na Yeo Division of Rheumatology, Department of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, South Korea In Cheol Hwang Department of Family Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, South Korea Hong Yup Ahn Department of Statistics, Dongguk University, Seoul, South Korea 2019 06 25 2019 07 20 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/17545 https://ijph.tums.ac.ir/index.php/ijph/article/download/17545/7453

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 12 2021 12 01 2604 2605 SungMan Yoon Department of Business Administration, Seoul National University of Science and Technology, Seoul, South Korea 2019 09 03 2019 09 18 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/18238 https://ijph.tums.ac.ir/index.php/ijph/article/download/18238/7454

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 12 2021 12 01 2606 2607 Fereshteh Ghorat Non-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran Mohammad Azizkhani Department of Iranian Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran Maryam khosrojerdi Non-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran Roholah Barghbani Non-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran 2019 07 14 2019 07 22 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/17746 https://ijph.tums.ac.ir/index.php/ijph/article/download/17746/7455

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 50 12 2021 12 01 2608