Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 4 2017 04 26 475 484 Yeunhee KWAK Faculty of Red Cross College of Nursing, Chung-Ang University, Seoul, Republic of Korea Ji-Su KIM Faculty of Red Cross College of Nursing, Chung-Ang University, Seoul, Republic of Korea 2017 04 26 2017 04 26 Background: Despite growing interest in the public health of sexual minority, youth around the world due to the high rates of suicidal ideation and attempts in this population, few studies on the sexual orientation of Korean adolescents have been conducted. Therefore, this study investigated the relationship between the sexual orientation of Korean adolescents and their suicide-related behavior. Methods: Raw data from the tenth Korea Youth Risk Behavior Web-based Survey were analyzed by logistic regression analysis. The sample consisted of 3603 adolescents who provided selected demographic variables and reported on their experience of sexual intercourse with the same or the opposite sex, along with lifestyle and suicide-related behaviors. Results: Rates of suicidal ideation, plans, attempts, and medically serious attempts were higher in both homosexual and bisexual than heterosexual groups. Suicidal ideation (odds ratio 95% confidence interval: 1.09–2.08), suicidal plans (odds ratio 95% confidence interval: 1.01–2.09), and suicide attempts (odds ratio 95% confidence interval: 1.28–2.88) had the strongest associations with homosexuality after multivariate adjustment. In contrast, bisexuality was only significantly associated with suicidal attempts (odds ratio 95% confidence interval: 1.01–2.97) after multivariate adjustment. Conclusion: Effective suicide prevention interventions are required for homosexual and bisexual adolescents, in the form of targeted programs to improve their mental health status and ability to cope with stress.       https://ijph.tums.ac.ir/index.php/ijph/article/view/9755 https://ijph.tums.ac.ir/index.php/ijph/article/download/9755/5626

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 4 2017 04 26 435 446 Sayyed Morteza HOSSEINI SHOKOUH Dept. of Health Services Management, Faculty of Health, Baqiyatallah University of Medical Sciences, Tehran, Iran Mohammad ARAB Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Sara EMAMGHOLIPOUR Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Arash RASHIDIAN Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Ali MONTAZERI Mental Health Research Group, Health Metrics Research Center, Institute for Health Sciences Research, ACECR, Tehran, Iran Rouhollah ZABOLI Dept. of Health Services Management, Faculty of Health, Baqiyatallah University of Medical Sciences, Tehran, Iran 2017 04 26 2017 04 26 Background: There are several conflicting conceptual models to explain social determinants of health (SDH) as responsible for most health inequalities. This study aimed to present these models in historical perspective and provide main component of SDH models as an SES indicators. Methods: This was a narrative study using international databases to retrieve literature dealing with conceptual models of SDH. All publication in English language until Mar 2015 was included. The CASP and PRISMA were used to summarize the literature. Results: Overall, 248 publications were retrieved and screened. After exclusion of irrelevant and duplicates, 94 citations were found to be relevant and 21 publications included in this review. In general, 21 models of SDH were found: some models presented before year 1995(n=4), some models presented between 1995 and 2005 (n=13) and some models presented after 2005 (n=4). However, we found three categories of indicators that contribute to SDH models and that were classic factors, fixed and demographic factors and proxy factors. Conclusion: Reduction of socioeconomic inequalities in health requires understanding of mechanisms and causal pathways; therefore, every country needs to design the specific model. As the available models are for developed countries, lack of a specific model for developing ones is tangible. As there is no gold standard related to SES indicators, therefore, it is proposed to use the various indicators based on life course approach, which leads to understanding and adopting effective policy interventions.   https://ijph.tums.ac.ir/index.php/ijph/article/view/9751 https://ijph.tums.ac.ir/index.php/ijph/article/download/9751/5622

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 4 2017 04 26 560 564 Masoumeh RAZIPOUR Dept. of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Daniz KOOSHAVAR Dept. of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Elaheh ALAVINEJAD Dept. of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Seyede Zahra SAJEDI Dept. of Medical Genetics, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran AND Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Neda MOHAJER Dept. of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Aria SETOODEH Dept. of Endocrinology, Children’s Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran Saeed TALEBI Dept. of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Mohammad KERAMATIPOUR Dept. of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran 2017 04 26 2017 04 26 Phenylketonuria (PKU) is an inborn error of amino acid metabolism with an autosomal recessive inheritance caused in most cases by mutations in the phenylalanine hydroxylase (PAH) gene. PKU has wide allelic heterogeneity. Here we report a novel heterozygous substitution (c.1223G>T (p.Arg408Leu)) in the PAH gene in an Iranian PKU family. The patient was 19-yr-old female with diagnosis of moderate PKU referred to Department of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran for genetic counseling/analysis in April 2015. We used PCR-Sequencing to identify any sequence variations in the PAH gene.     https://ijph.tums.ac.ir/index.php/ijph/article/view/9767 https://ijph.tums.ac.ir/index.php/ijph/article/download/9767/5663

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 4 2017 04 26 565 567 Yu-Ri CHOI Dept. of Dental Hygiene, Hallym Polytechnic University, Chuncheon, Republic of Korea Youn-Soo SHIM Dept. of Dental Hygiene, College of Health Science, Sunmoon University, Asan, Republic of Korea Sun-Ok JANG Dept. of Dental Hygiene, Hallym Polytechnic University, Chuncheon, Republic of Korea Seoul-Hee NAM Dept. of Dental Hygiene, Kangwon National University, Samcheok, Republic of Korea Gyeong-Soon HAN Dept. of Dental Hygiene, College of Health Science, Gachon University, Incheon, Republic of Korea 2017 04 26 2017 04 26 Awareness and Work Changes of Dental Hygienists about Newly Covering Health Insurance Benefit for Scaling https://ijph.tums.ac.ir/index.php/ijph/article/view/9768 https://ijph.tums.ac.ir/index.php/ijph/article/download/9768/5664

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 4 2017 04 26 485 490 Lanlan ZHOU Dept. of Hematology and Oncology, The Second People’s Hospital of Hefei, Hefei, Anhui, China Mingjun WANG Dept. of Hematology, Liaocheng People’s Hospital, Liaocheng, Shandong , China Aping LI Dept. of Neurosurgery, People’s Hospital of Haiyang City, Haiyang, Shandong, China 2017 04 26 2017 04 26 Background: Peripherally inserted central catheter (PICC) is commonly used in nursing for patients with leukemia. The purpose of this study was to investigate the risk factors of Catheter-related infection (CRI) in patients with leukemia and to provide some nursing strategies based on the results. Methods: Clinical data from 140 patients with leukemia between May 2014 and July 2016 in Haiyang People's Hospital, China were retrospectively analyzed. We employed univariate analysis to explore the relationship of various factors, including leukemia types, puncture times, underlying diseases, Catheter indwelling time, hormones use, chemotherapy use, immune functions and seasons, with the incidence of CRI. Further, multivariate logistic regression analysis was conducted to identify the potential independent risk factors of CRI. Bacterial culture was performed for etiological detection. Results: Among the 140 patients with leukemia, 25 cases were diagnosed as CRI, with the incidence of 17.9%. Univariate analysis showed that puncture times, underlying diseases, catheter indwelling time, hormones use, chemotherapy use, immune functions and seasons were significantly correlated with the incidence of CRI. Multivariate logistic regression analysis revealed that immune functions, puncture times and seasons were independent risk factors for CRI. Etiological bacterial culture detected 20 strains of bacteria (Staphylococcus aureus: n=10, Klebsiella pneumonia: n=4, Corynebacterium: n=2 and other species: n=4) in 25 cases diagnosed with CRI. Conclusion: Based on risk factors of CRI and its etiological distribution, appropriate nursing measures can be taken to reduce the incidence of CRI in patients with leukemia.       https://ijph.tums.ac.ir/index.php/ijph/article/view/9756 https://ijph.tums.ac.ir/index.php/ijph/article/download/9756/5627

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 4 2017 04 26 447 455 Ahmad MOOSAVI Dept. of Health and Community Medicine, Dezful University of Medical Sciences, Dezful, Iran Mohammad MOHSENI Health Services Management Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran Hajar ZIAIIFAR Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Saber AZAMI-AGHDASH Iranian Center of Excellence in Health Management, Tabriz University of Medical Sciences, Tabriz, Iran Mahdi GHARASI MANSHADI Dept. of Health Services Administration, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Aziz REZAPOUR Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran AND Dept. of Health Economics, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran 2017 04 26 2017 04 26 Background: Students' view is an important factor in assessing the quality of universities. Servqual pattern is regarded as the most prominent for services quality measurement. This study aimed to review systematically studies that investigated the quality of educational services. Methods: A systematic review and meta-analysis of studies evaluating students’ viewpoint about quality of educational services were conducted. Required data were collected from PubMed, Embase, Scopus, Science Direct, Google Scholar, SID, Magiran, and Iranmedex, without time restriction. Computer software CMA, ver. 2 was applied to estimate the total mean score of students’ perception and expectation of services quality and the gap between them. Results: The 18 eligible studies were entered into study. The studies were conducted between 2004 and 2014. Based on the random effect model, the total mean score of students’ perception, students’ expectation and the gap between them were estimated 2.92 (95% CI, 2.75 - 3.09), 4.18 (95% CI, 3.98 - 4.38), respectively and -1.30 (95% CI= -1.56, -1.04). Conclusion: The studied students' expectation level is higher than the current quality of educational services. There is a tangible difference between their expectations and the current quality, which requires officials' efforts to improve quality in all dimensions and effective steps can be taken towards improving the quality of educational services through appropriate training planning and training for empowering employees in colleges and universities.   Keywords: Servqual, Services quality, Student, Meta-analysis, Iran https://ijph.tums.ac.ir/index.php/ijph/article/view/9752 https://ijph.tums.ac.ir/index.php/ijph/article/download/9752/5623

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 4 2017 04 26 568 570 Vasile Mircea ZĂGREANU Emergency County Hospital, Baia Mare, Romania Dana POP University of Medicine and Pharmacy, Cluj-Napoca, Romania Mihnea ZDRENGHEA University of Medicine and Pharmacy, Cluj-Napoca, Romania Adela SITAR-TAUT University of Medicine and Pharmacy, Cluj-Napoca, Romania Bogdan CALOIAN University of Medicine and Pharmacy, Cluj-Napoca, Romania Dumitru Tudor ZDRENGHEA University of Medicine and Pharmacy, Cluj-Napoca, Romania 2017 04 26 2017 04 26 >08 22 2023 10 20 Background: Various studies have highlighted the usefulness of environmental scanning in assessing community needs and developing programs and policies. We aimed to find the most practical model of using such scanning in the healthcare literature. Methods: We conducted a scoping review based on the PRISMA guideline to ensure a comprehensive and systematic approach in 2023. To develop a comprehensive search strategy, we worked with experienced librarians and the research team. We then completed a search of five electronic databases, including Web of Science, PubMed, Scopus, Cochrane, and Embase databases. Two independent reviewers screened titles, abstracts, and full-text articles to select studies that met our inclusion criteria. The data was then analyzed and presented in a tabular format to facilitate easy interpretation and understanding. Results: We retrieved 7243 articles from various databases and sources. After removing 2755 articles due to duplication, we excluded 4380 more articles during the title and abstract screening phase. In the full-text review process, we ruled out an additional 103 articles. Finally, only 5 articles that were directly relevant to the study were included. The model that Bednar and colleagues have in their article is the latest model. Most studies propose six main steps to conduct an environmental survey in the healthcare system. Conclusion: Since the most important task of managers and policy makers of the health system is to make decisions, they can use our proposed model to collect, analyze and interpret data, identify important patterns and trends so that they can make evidence-based decisions.   Keywords: ; Scan; Model;; ; https://ijph.tums.ac.ir/index.php/ijph/article/view/32973 https://ijph.tums.ac.ir/index.php/ijph/article/download/32973/8258

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1272 1283 Elham Amini Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran Mohammad Heidarzadeh Department of Pediatrics, School of Medicine, Zahedan University of Medical Science, Zahedan, Iran Leila Ahmadian Department of Health Information Sciences, Faculty of Management and Medical Information Sciences, Kerman University of Medical Sciences, Kerman, Iran Shahram Ariafar Department of Industrial Engineering, Faculty of Engineering, Shahid Bahonar University of Kerman, Kerman, Iran Mohammadreza Amiresmaili Health in Disasters and Emergencies Research Center, Kerman University of Medical Sciences, Kerman, Iran 2023 04 26 2023 10 20 Background: Neonatal mortality remains a critical global challenge, with preventable instances prevailing. The initial stride in mitigating neonatal mortality involves elucidating its underlying causes. Methods: This study utilized an umbrella review approach to discern factors associated with neonatal mortality. Five international databases, namely Pub Med, Web of Science, Scopus, CINAHL, and EMBASE, were meticulously searched to achieve this. Results: The initial search yielded 12,631 articles using a search strategy centered on keywords related to factors contributing to neonatal mortality. Ultimately, 95 articles met the criteria incorporated into this study. Conclusion: This study endeavors to identify the primary risk factors contributing to neonatal mortality. The discerned risk factors have been systematically categorized into four groups: maternal factors, neonatal factors, aspects linked to healthcare systems, and socio-economic factors. As such, it is imperative for policymakers to take heed of these identified risk factors and formulate comprehensive strategies encompassing both long-term and short-term initiatives. Effective interventions spanning various sectors are crucial for the prevention of neonatal mortality.   https://ijph.tums.ac.ir/index.php/ijph/article/view/31861 https://ijph.tums.ac.ir/index.php/ijph/article/download/31861/8259

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1284 1292 Li Zhang School of Economics & Management, Wuchang Institute of Technology, Wuhan, Hubei, China Xu Chen School of Economics & Management, Wuchang Institute of Technology, Wuhan, Hubei, China Liang Zhu School of Economics & Management, Wuchang Institute of Technology, Wuhan, Hubei, China 2024 04 16 2024 06 11 Background: Mobile phone addiction in adolescents is a serious social problem that not only negatively affects physical and mental health but also hinders social stability and development. However, studies on interventions for mobile phone addiction in adolescents are still few. Therefore, exploring interventions for mobile phone addiction in adolescents and scrutinizing the corresponding mechanism of action are crucial. Methods: A questionnaire survey was conducted on 800 adolescents who were recruited using random sampling from communities in Hubei Province, China in 2023, and 232 of them were identified to have mobile phone addiction. Then, they were randomly divided into the experiment group, comprising 119 members, and the control group, composed of 113 members. The experiment group was given a 3-month intervention under the Health Action Process Approach (HAPA) model, whereas the control group was given no intervention. Results: This intervention significantly reduced the level of mobile phone addiction in adolescents (P<0.05). It also significantly improved self-efficacy in adolescents with mobile phone addiction (P<0.05). The intervention can significantly improved life satisfaction in adolescents with mobile phone addiction (P<0.05). Self-efficacy and life satisfaction had a chain mediating effect (P<0.001). Conclusion: The HAPA model is conducive to alleviating mobile phone addiction. It further enhances the intervention effect by improving self-efficacy and life satisfaction in adolescents. https://ijph.tums.ac.ir/index.php/ijph/article/view/35244 https://ijph.tums.ac.ir/index.php/ijph/article/download/35244/8260

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1293 1303 EN Bedriye Ural Department of Nutrition and Dietetics, Hamidiye Faculty of Health Sciences, University of Health Sciences, Istanbul, Turkey Esin sezgin Department of Child Development, Sandıklı School of Applied Sciences, Afyon Kocatepe University, Afyon, Turkey Elvan Yilmaz-Akyuz Department of Nutrition and Dietetics, Hamidiye Faculty of Health Sciences, University of Health Sciences, Istanbul, Turkey 2023 01 17 2023 06 02 Background: Healthy nutrition and good quality sleep are one of the most important factors for growth and development in a child. Digital game addiction may cause some problematic behaviors and affect children's nutrition and sleep. We aimed to investigate the relationship between digital game addiction, eating behavior, and sleep disorders in children. Methods: The study was conducted with 252 mothers with children between the ages of 4-7 years, selected by convenient sampling methods. The Digital Game Addiction Scale, Children's Eating Behavior Questionnaire and The Sleep Disturbance Scale for Children (SDSC) were used to collect data. The correlation coefficient and the decision tree CHAID algorithm were used in the data analysis. Results: Digital game addiction negatively affects children's eating behavior and sleep patterns. It was found that there was a mostly positive but weakly significant relationship between digital game addiction and children's eating behaviors (P<.01; P<.05) and a highly significant relationship was found between the sleep disorder scale sleep hyperhidrosis sub-dimension (P<.05). While digital game addiction is affected by gender, the mother's education level, and eating behavior are affected by the mother's age, the parent's education level, and the child's gender (P<.05). The child's age is the variable that affects the children's sleep disorder (P<.05). Conclusion: Intervention programs for children and families can be created for the causes of digital game addiction, its effects on child development and the correct use of the digital world.   https://ijph.tums.ac.ir/index.php/ijph/article/view/30961 https://ijph.tums.ac.ir/index.php/ijph/article/download/30961/8261

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1304 1312 Jiwoo Jung Department of Nursing, Graduate School of Chung-Ang University,84 Heukseok-ro Dongjak-gu, Seoul 06974, Korea Jinna Yu Department of Nursing, Yeungnam University College,Hyeonchung-ro, Nam-gu, Daegu 42415, Korea Nam-Jun Kim College of Medicine, Catholic Kwandong University, Bumil-ro, Gangneung-si, Gangwon-do 25601, Korea Yeunhee Kwak Red Cross College of Nursing, Chung-Ang University, Heukseok-ro Dongjak-gu, Seoul 06974, Korea 2023 03 08 2023 09 09 Background: The purpose of this cross-sectional study was to assess the relationship between oral health, unmet dental needs and health-related quality of life in South Korea older adults. Methods: The present study used raw data from the 2019~2020 Korea National Health and Nutrition Examination Survey, and analyzed 4956 participants aged over 65 yr. Hierarchical multiple regression analysis was used for associations between oral health, unmet dental needs, and HRQoL. Results: The EQ-5D index differed according to tooth pain, chewing difficulty, speaking problem, subjective oral health status, oral examination, and unmet dental care needs (P<0.001). In the model 2, male, under 75 yr of age, high school graduate or higher, employed, living with a spouse, no stress, good subjective health status, no speaking problem, and no unmet dental care needs were associated with higher EQ-5D index (Adj R2 = 27.6%, P<0.001). Conclusion: To improve the HRQoL of older adults in South Korea, oral health problems need to be minimized through oral disease prevention and oral health education programs. https://ijph.tums.ac.ir/index.php/ijph/article/view/31419 https://ijph.tums.ac.ir/index.php/ijph/article/download/31419/8262

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1313 1321 Yingli Li Department of Otolaryngology, the Third Affiliated Hospital of Qiqihar Medical College, Qiqihar City, Heilongjiang Province, 161000, China Qian Yang Department of Otolaryngology, the Third Affiliated Hospital of Qiqihar Medical College, Qiqihar City, Heilongjiang Province, 161000, China Xin Wang Department of Otolaryngology, the Third Affiliated Hospital of Qiqihar Medical College, Qiqihar City, Heilongjiang Province, 161000, China Lin Liu Department of Otolaryngology, the Third Affiliated Hospital of Qiqihar Medical College, Qiqihar City, Heilongjiang Province, 161000, China Yang Li Department of Otolaryngology, the Third Affiliated Hospital of Qiqihar Medical College, Qiqihar City, Heilongjiang Province, 161000, China Ying Zhang Department of Otolaryngology, the Third Affiliated Hospital of Qiqihar Medical College, Qiqihar City, Heilongjiang Province, 161000, China Bo Wang Department of Neurology, the Third Affiliated Hospital of Qiqihar Medical College, Qiqihar City, Heilongjiang Province, 161000, China 2023 08 14 2024 06 11 Background: To explore the perioperative effect of the evaluation system of nursing quality in otorhinolaryngology patients. Methods: A total of 100 patients hospitalized in the Department of Otorhinolaryngology of the Third Affiliated Hospital of Qiqihar Medical College, Qiqihar City, China in 2019 were selected as the control group, and routine nursing mode was adopted. The control group was data before the implementation of this study. A total of 100 patients (experimental group) hospitalized in the Department of Otolaryngology in 2020 were selected to adopt the nursing model constructed by nursing quality evaluation system. The adverse mood of patients in the two groups were evaluated at admission and discharge, and postoperative pain and satisfaction were compared between the two groups. Results: Anxiety, depression and quality of life scores were improved in both groups, but the degree of improvement in experimental group was significantly higher than that in control group (t=481.759, 353.502, P＜0.05）, and the postoperative pain score in experimental group was lower than that in control group (t=54.086, P＜0.05). The satisfaction of experimental group was better than that of control group (χ2=30.327, P＜0.05). Conclusion: The nursing model based on the evaluation system of the nursing quality of otorhinolaryngology can relieve patients' adverse emotions, relieve postoperative pain of otorhinolaryngology patients, and improve patient satisfaction. Therefore, it is worth popularizing and applying in the future. https://ijph.tums.ac.ir/index.php/ijph/article/view/32898 https://ijph.tums.ac.ir/index.php/ijph/article/download/32898/8263

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1322 1331 Milena Zlatanovic 1. Department of Medical Studies, The Academy of Applied Preschool Teaching and Health Studies Krusevac, Cuprija, Serbia 2. Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Ardea Milidrag Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Marija Sorak Department of Gynecology and Obstetrics, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Sanja Kocic Department of Social Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Aleksandar Visnjic Department of Social Medicine and Public Health, Faculty of Medicine, University of Niš, Niš, Serbia Mile Despotovic Department of Medical Studies, The Academy of Applied Preschool Teaching and Health Studies Krusevac, Cuprija, Serbia Teodora Safiye Department of Psychology, State University of Novi Pazar, Novi Pazar, Serbia Milena Despotovic Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Christos Alexopoulos Department of Medical Studies, The Academy of Applied Preschool Teaching and Health Studies Krusevac, Cuprija, Serbia Svetlana Radevic Department of Social Medicine, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia 2024 04 08 2024 06 11 Background: This study aimed to examine the quality of life and the factors that determine the quality of life of infertile couples. Methods: The research was conducted as a cross-sectional study at the Gynecology and Obstetrics Clinic "Narodni Front" in Belgrade, the Special Gynecology Hospital "Ferona" in Novi Sad, the Special Hospital for the Treatment of Sterility and In Vitro Fertilization "Spebo Medikal" in Leskovac and the General Hospital in Valjevo, Serbia in 2022, on a sample of 378 infertile couples. The data were collected by means of a questionnaire, the integral part of which is the standardized FertiQoL scale. Independent t-test and one-way ANOVA were used to determine differences. A value of P<0.05 was considered statistically significant. Results: Women achieve a significantly lower score on the quality of life questionnaire (69.34±11.05) compared to men (73.96±9.87). Women exhibit significantly lower scores in the area of physical, emotional and social functioning (P<0.05). Men who live in the countryside show a lower quality of life score in the emotional (P=0.029) and social (P=0.042) domains. In addition, men over 40 years of age and with a high level of education have a lower quality of life (P=0.08). Conclusion: Women have a lower quality of life, as do men from rural areas and over 40 years of age. A multidisciplinary approach and community education, as well as the provision of social support with a special emphasis on emotional and material support, would significantly contribute to improving the quality of life of infertile couples. https://ijph.tums.ac.ir/index.php/ijph/article/view/35110 https://ijph.tums.ac.ir/index.php/ijph/article/download/35110/8264

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1332 1342 Amir Shourideh Faculty of Pharmacy, Eastern Mediterranean University, Famagusta, Cyprus Reza Maddah Department of Bioprocess Engineering, Institute of Industrial and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran Bahareh Shateri Amiri Department of Internal Medicine, School of Medicine Hazrat-e Rasool General Hospital Iran University of Medical Sciences, Tehran, Iran Zarrin Basharat Alpha Genomics Private Limited, Islamabad 45710, Pakistan Marzieh Shadpirouz Department of Applied Mathematics, Faculty of Mathematical Sciences, Shahrood University of Technology, Semnan, Iran 2023 05 03 2023 08 14 Background: Liver hepatocellular carcinoma (LIHC) is a common cancer with a poor prognosis and high recurrence rate. We aimed to identify potential biomarkers for LIHC by investigating the involvement of hub genes, microRNAs (miRNAs), transcription factors (TFs), and protein kinases (PKs) in its occurrence. Methods: we conducted a bioinformatics analysis using microarray datasets, the TCGA-LIHC dataset, and text mining to identify differentially expressed genes (DEGs) associated with LIHC. They then performed functional enrichment analysis and gene-disease association analysis. The protein-protein interaction network of the genes was established, and hub genes were identified. The expression levels and survival analysis of these hub genes were evaluated, and their association with miRNAs, TFs, and PKs was assessed. Results: The analysis identified 122 common genes involved in LIHC pathogenesis. Ten hub genes were filtered out, including CDK1, CCNB1, CCNB2, CCNA2, ASPM, NCAPG, BIRC5, RRM2, KIF20A, and CENPF. The expression level of all hub genes was confirmed, and high expression levels of all hub genes were correlated with poor overall survival of LIHC patients. Conclusion: Identifying potential biomarkers for LIHC can aid in the design of targeted treatments and improve the survival of LIHC patients. The findings of this study provide a basis for further research in the field of LIHC and contribute to the understanding of its molecular pathogenesis.   https://ijph.tums.ac.ir/index.php/ijph/article/view/31921 https://ijph.tums.ac.ir/index.php/ijph/article/download/31921/8265

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1343 1351 Yang Li Department of Medical Examination, the Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, Chi-na Yu Wang Ward 2, Department of Neurology, the Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China Teng Zhao Department of Intensive Care Medicine, the Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, Chi-na Xuewen Yang Department of Nursing, the Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China Yinghui Lv Department of Geriatrics, the Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China Shumei Li The General Practice Ward, the Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China Xiujun Yang Honorable Community, the Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China Li Li Department of Nursing, the Third Affiliated Hospital of Qiqihar Medical University, Qiqihar 161000, China 2023 08 30 2024 06 11 Background: We aimed to explore the effect of multi-sensory stimulation on apathy symptoms in elderly patients with Alzheimer's disease (AD). Methods: Eighty elderly patients with AD admitted to the Third Affiliated Hospital of Qiqihar Medical University, China from January 2022 to February 2023 were selected as the research objects by convenient sampling method. According to the random number table, they were divided into intervention group and control group, with 40 cases in each group. The control group was given routine nursing, while the intervention group was given multi-sensory stimulation based on this nursing. Apathy evaluation scale (AES), Behavioral pathology in Alzheimer’s disease rating scale (BEHAVE-AD) and Quality of Life Scale for dementia patients（QoL-AD） were used to compare the results. Results: Compared with the control group, the scores of AES and BEHAVE-AD in intervention group were lower (t was -7.312 and 11.88 respectively, P < 0.05), and the scores of QoL-AD in intervention group were significantly higher than those in control group were (t was -15.311, P < 0.01). Conclusion: Multi-sensory stimulation can relieve apathy symptoms, mental and behavioral symptoms and improve the quality of life of elderly patients with AD, which is worth popularizing in clinical practice. https://ijph.tums.ac.ir/index.php/ijph/article/view/33075 https://ijph.tums.ac.ir/index.php/ijph/article/download/33075/8266

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1352 1360 Myoung Ho Lee Research Institute for Indramang, Indramang Community, JeonBuk, South Korea Ladan Rokni Asia Contents Institute, Konkuk University, Seoul, South Korea Eunyoung Lee Departmnt of Philosophy, Kyung Hee University, Seoul, South Korea Sangduk Lee Institute of Humanities, Kyung Hee University, Seoul, South Korea 2024 02 16 2024 06 11 Background: The research was designed to investigate the perceptions and attitudes of immigrants towards extra medical support programs that Immigrant Support Centers (ISC) offer. We aimed to find how they evaluate such medical support in terms of helpfulness for social integration in the host country. Methods: The study was performed in South Korea during May-June 2023. A questionnaire was prepared in six languages, with 132 participants. The survey categorized the respondents into three groups, group (A) that received only medical support, group (B) that received only cultural support, and group (C) that received both. The statistical program SPSS windows 22.0 was used for the analysis, and finding the most effective way of medical and cultural support programs was verified through inter-group analysis. Results: The analysis of the results shows that the immigrants find the biggest hardship in the new country when a health problem occurs. The most significant barriers were language differences and cultural differences. The immigrants’ participation in the extra medical support programs can address those barriers. However, time, age, and length of stay were significant factors, and most of the participants found the extra cultural support more effective at the earlier stage of their stay in Korea. Discussion: The study suggests that it is important to provide both medical and cultural support in the early stage of the immigrants staying in another country. Indeed, this might be a way to use medical support to induce them to further adaptation. Besides, providing culturally oriented medical support is likely to foster social integration through medical support. https://ijph.tums.ac.ir/index.php/ijph/article/view/34641 https://ijph.tums.ac.ir/index.php/ijph/article/download/34641/8267

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1361 1371 Chawin Suwanchatchai Department of Preventive and Community Medicine, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok 26120, Thailand Kitsarawut Khuancharee Department of Preventive and Community Medicine, Faculty of Medicine, Srinakharinwirot University, Nakhon Nayok 26120, Thailand Chantra Tanunyutthawongse Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand Sivaporn Wannaiampikul Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand Photsathorn Haetanurak Department of Physiology, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand 2023 05 29 2023 09 09 Background: Although the prevalence of HUA is increasing, epidemiologic studies on HUA in the middle-aged and elderly population are limited. The present study aimed to calculate the prevalence and evaluate the sex-related associations between metabolic parameters and hyperuricemia (HUA) among middle-aged and elderly adults. Methods: This was a population-based cross-sectional study from 2018 to 2019 in rural areas of Nakhon Nayok Province, Thailand. We enrolled 780 subjects aged 40 yr and over for health check-ups and examination surveys. The age-standardized prevalence of HUA was estimated by the direct method. A multiple logistic regression was performed to identify the potential risk factors associated with HUA. Results: The prevalence of HUA were 30.9% (42% in males vs. 20% in females). Elderly adults were associated with a 35% increase in the risk of HUA. Obesity was found to be strongly associated with an increased prevalence of HUA in both sexes. Hypertriglyceridemia (51% increase in males vs. 23% increase in females), and high fasting glucose (90% increase in males vs. 49% increase in females) were also associated risk factors for HUA in both sexes. However, low high-density lipoprotein was only associated with a 67% increase in the risk of HUA in females. Conclusion: The age-standardized prevalence of HUA among females is relatively lower than in males. This study also revealed that obesity is strongly associated with HUA in both sexes. https://ijph.tums.ac.ir/index.php/ijph/article/view/32146 https://ijph.tums.ac.ir/index.php/ijph/article/download/32146/8268

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1372 1380 Agung Laksono National Research and Innovation Agency Republic of Indonesia, Jakarta, Indonesia Ratna Wulandari Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia Zuardin Zuardin Faculty of Psychology and Health, UIN Sunan Ampel, Surabaya, Indonesia Hadi Ashar National Research and Innovation Agency Republic of Indonesia, Jakarta, Indonesia Mara Ipa National Research and Innovation Agency Republic of Indonesia, Jakarta, Indonesia Agung Kesuma National Research and Innovation Agency Republic of Indonesia, Jakarta, Indonesia 2023 02 23 2023 08 13 Background: The poor are vulnerable when they fall seriously ill and require hospitalization. The study aimed to analyze the factors related to hospital inpatients among the poor in Indonesia. Methods: We analysed the 2018 Indonesian Basic Health Survey data. This cross-sectional study examined 233778 respondents through stratification and multistage random sampling. We used seven independent variables age, gender, marital status, education, employment, and health insurance, in addition to the hospital inpatient, as a dependent variable. We employed binary logistic regression to evaluate the data. Results: The poor in urban areas were 1.315 times more likely to be hospital inpatients than those in rural areas (95%CI 1.249-1.385). Age, gender, and marital status were related to the hospital inpatients. The better the education level, the higher the hospital inpatient proportion. Meanwhile, the employed were 40% less likely than the unemployed to be hospital inpatients (95%CI 0.565-0.634). Furthermore, the insured were 3.513 times more likely than the uninsured to be hospital inpatients (95%CI 3.264-3.780). Conclusion: Seven variables were related to hospital inpatients among the poor in Indonesia: residence, age, gender, marital status, education, employment, and health insurance. Health insurance was the main factor associated with hospital inpatients among low-income people. The government must increase the subsidy quota for the poor's participation in National Health Insurance. https://ijph.tums.ac.ir/index.php/ijph/article/view/31313 https://ijph.tums.ac.ir/index.php/ijph/article/download/31313/8269

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1381 1393 Dariush D. Farhud 1. School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2. Department of Basic Sciences, Iranian Academy of Medical Sciences, Tehran, Iran 3. Research Institute of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran Marjan Zarif-Yeganeh 1. Research Institute of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran 2. Dr. Farhud Genetics Clinic, Tehran, Iran Hajar Arian 1. Research Institute of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran 2. Dr. Farhud Genetics Clinic, Tehran, Iran Majid Kashi Tabnak Radiology Center, Tehran, Iran Tayebeh Rezaee Surgical Research Center, Department of Surgery, University of Connecticut Health Center, Farmington, CT, USA 2024 06 11 2024 06 11 Background: Brucellosis is one of the common diseases between humans and animals. We aimed to assess the annual incidence rate, the geographical distribution of Malta fever using GIS and its time trend. Methods: This was an ecology study carried out in exploratory mixed design. The study population was the individuals with brucellosis in Iran during the years 2009-2018. Data analysis has been done using Joinpoint regression analysis and GIS at a significant level of α = 0.05. Results: The average annual incidence rate of the disease rate was 19.91 per one hundred thousand people. The trend of the changes in the incidence between 2009 and 2018 has increased and the Annual Average Percent Change increased by 4.6%. However, a joinpoint was observed in 2014 and the incidence has changed significantly at this point in time, so that the annual incidence of the disease has increased more strongly between 2009 and 2014 (APC=17.1%) and then from 2014 to 2018, the incidence of the disease has decrease (APC=-9.2%). The spatial distribution showed that the western and northwestern provinces have high incidence rate, but the northern and southern provinces have low incidence rate. Conclusion: The incidence of brucellosis in Iran is higher than in developed countries and similar to developing countries. Ten-year trend of disease incidence increased slightly, but it has decreased in recent years. It is necessary to improve the surveillance system and increase facilities for prevention and treatment in the high-risk areas including the west and northwest of Iran. https://ijph.tums.ac.ir/index.php/ijph/article/view/35787 https://ijph.tums.ac.ir/index.php/ijph/article/download/35787/8271

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1394 1403 Akram Hemmatipour Department of Nursing, Abadan University of Medical Sciences, Abadan, Iran Bijan Kikhaei Thalassemia and Hemoglobinopathy Research Center, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran Razieh Jalkani Department of Hematology and Blood Banking, Faculty of Allied Medicine, Bushehr University of Medical Scince, Bushehr, Iran Mansour Ahmadnejad Student Research Center of Shoushtar Faculty of Medical Sciences, Shoushtar, Iran Farhad Soleimanzadeh Department of Nursing, Nursing Care Research Center in Chronic Diseases, School of Nursing and Midwifery, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran Dariush Rokhafrooz Department of Nursing, Nursing Care Research Center in Chronic Diseases, School of Nursing and Midwifery, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran 2023 05 13 2023 08 14 Background: We aimed to determine the level of serum vitamin D and serum ferritin in four groups’ children and adolescents. Methods: This descriptive/analytical study was conducted in 2019 on children and adolescents with thalassemia aged 7-18 years in Ahvaz, Iran. Overall, 160 patients with the target inclusion and exclusion criteria were assigned into four groups (n=40) of people with thalassemia minor, thalassemia major, iron deficiency anemia and healthy individuals. The level of ferritin and vitamin D was assessed. Mann-Whitney test, Wilcoxon test and Spearman's correlation test were used as well as SPSS Statistics V21. Results: The mean age of the participants was 13.07 ± 3.82 yr and 100 people (62.5%) were male. In terms of vitamin D deficiency, 16 people (40%) had severe deficiency in iron deficiency group. The highest level of ferritin was found in thalassemia major group and the lowest in iron deficiency group. Regarding the level of vitamin D and ferritin in the healthy group, there was a statistically significant difference between mean vitamin D and serum ferritin levels (P=0.027). In iron deficiency group, this level of ferritin was observed with mild deficiency (P=0.017). In thalassemia major group, the increase in ferritin was associated with severe vitamin D deficiency (P=0.05. Conclusion: Severe vitamin D is seen in thalassemia major due to the increase in ferritin, but moderate deficiency of this vitamin in healthy people and mild deficiency in iron deficiency anemia group was observed considering the normal levels of ferritin. https://ijph.tums.ac.ir/index.php/ijph/article/view/32024 https://ijph.tums.ac.ir/index.php/ijph/article/download/32024/8272

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1404 1415 Reza Maddah Department of Bioprocess Engineering, Institute of Industrial and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran Sareh Etemad Department of Pathology, Faculty of Anatomical Pathology Ghaem Hospital, University of Medicine, Mashhad, Iran Bahareh Shateri Amiri Department of Internal Medicine, School of Medicine Hazrat-e Rasool General Hospital Iran University of Medical Sciences, Tehran, Iran Hajarossadat Ghaderi Laboratory of Regenerative and Medical Innovation, Pasteur Institute of Iran, Tehran, Iran Hamidreza Zarei Department of Internal Medicine, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Ferdos Faghihkhorasani Medical Campus, Xian Jiaotong University, Xian, Shaanxi Province, China Hadi Rezaeeyan Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Iranian Blood Transfusion Organization (IBTO), Tehran, Iran 2023 03 09 2023 08 22 Background: Sickle cell disease (SCD) is one of the hematological disorders characterized by a defect in the structure and function of globin chains. Hereditary factors play an important role in the pathogenesis of SCD. We aimed to investigate the genes and pathways related to the pathogenesis of SCD. Methods: Microarray dataset was downloaded from the Gene Expression Omnibus (GEO) database. LIMMA package of R-software was used to detect UP and Down regulations between SCD and control subjects. Enrichment analysis and Protein-protein interaction (PPI) networks were performed using GeneCodis4 software and GeneMANIA database, respectively. PrognoScan database was used to evaluate the relationship between the hub genes and patients' survival. Results: Overall, 447 DEGs were identified in SCD patients compared to control subjects. Out of 447 DEGs, 345 genes were up-regulated and 102 genes were down-regulated. Effective hub genes in SCD pathogenesis include SLC4A1, DTL, EPB42, SNCA, and TOP2A. In addition, hub genes had a high diagnostic value. Conclusion: Evaluation of hub genes in SCD can be used as a diagnostic panel to detect high-risk patients. In addition, by identifying the UP and Down stream pathways, treatment strategies in the monitoring and treatment of patients can be designed. https://ijph.tums.ac.ir/index.php/ijph/article/view/31431 https://ijph.tums.ac.ir/index.php/ijph/article/download/31431/8273

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 6 2024 06 11 1416 1426 Negar Bizhani 1. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2. Center for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Tehran, Iran Giorgia Vincenti Cultural Heritage Department, Physical Anthropology Laboratory, University of Salento, Italy Seyyed Mansur Seyyed Sajjadi Iranian Center for Archaeological Research (ICAR), Tehran, Iran Jean Dupouy-Camet Parasitol