Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1577 1585 Hua-Ning ZHANG Shandong Center for Disease Control and Prevention, Academy of Preventive Medicine, Shandong Provincial Key Laboratory of Infectious Diseases Control and Prevention, Jinan, China Pei-Bin HOU Shandong Center for Disease Control and Prevention, Academy of Preventive Medicine, Shandong University, Jinan, China AND Shandong Provincial Key Laboratory of Infectious Diseases Control and Prevention, Jinan, China Yu-Zhen CHEN Shandong Center for Disease Control and Prevention, Academy of Preventive Medicine, Shandong University, Jinan, China AND Shandong Provincial Key Laboratory of Infectious Diseases Control and Prevention, Jinan, China Yu MA Railway Center for Disease Control and Prevention, Beijing, China Xin-Peng LI Shandong Center for Disease Control and Prevention, Academy of Preventive Medicine, Shandong University, Jinan, China AND Shandong Provincial Key Laboratory of Infectious Diseases Control and Prevention, Jinan, China Hui LV Shandong Center for Disease Control and Prevention, Academy of Preventive Medicine, Shandong University, Jinan, China AND Shandong Provincial Key Laboratory of Infectious Diseases Control and Prevention, Jinan, China Mei WANG Shandong Center for Disease Control and Prevention, Academy of Preventive Medicine, Shandong University, Jinan, China AND Shandong Provincial Key Laboratory of Infectious Diseases Control and Prevention, Jinan, China Hai-Lian TAN Shandong Center for Disease Control and Prevention, Academy of Preventive Medicine, Shandong University, Jinan, China AND Shandong Provincial Key Laboratory of Infectious Diseases Control and Prevention, Jinan, China Zhen-Wang BI Shandong Center for Disease Control and Prevention, Academy of Preventive Medicine, Shandong University, Jinan, China AND Shandong Provincial Key Laboratory of Infectious Diseases Control and Prevention, Jinan, China 2016 12 27 2016 12 27 Background: Current food safety issues are deleteriously reshaping the lifestyle of the population in the developing world. The globalization of food supply impacts patterns of foodborne disease outbreaks worldwide, and consumers are having increased concern about microbiological food safety. Methods: A total of 2305 samples including sauced meat, sausage, smoked meat, shrimp, sashimi and shellfish were collected from different farmer's markets and supermarkets. The prevalence of selected foodborne pathogens was evaluated in cooked meat and seafood from 2010 to 2013 in Shandong Province, China. Results: The average contamination rate was 6.39% (93.1456) for the selected pathogens in cooked meat and 16.84% (143.849) for V. parahaemolyticus in seafood. For the selected pathogens, 0.55%, 1.03%, 1.17%, 3.64% and 16.84% samples were contaminated with E. coli O157: H7, Salmonella spp., L. monocytogenes, S. aureus and VP, respectively. There was a significant (P<0.05) difference in the contamination rate between the farmer's markets and supermarkets. Conclusion: The contamination was decreasing in cooked meat and maintaining a relatively high level in seafood from 2010 to 2013. E. coli O157: H7, S. aureus, L. monocytogenes and Salmonella spp. existed at a relatively low rate in retail foods. For VP, the contamination rate has been maintained at a relatively high level in Shandong Province in China. Moreover, cooked meat and seafood obtained from farmer's markets are more susceptible to be contaminated compared to those from supermarkets.   https://ijph.tums.ac.ir/index.php/ijph/article/view/8632 https://ijph.tums.ac.ir/index.php/ijph/article/download/8632/5401

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1533 1544 Xin WU Dept. of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha, Hunan, China Jieru WANG Dept. of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha, Hunan, China AND Dept. of Pediatrics, School of Medicine, University of Pittsburgh, Pennsylvania, USA Reuben COFIE Dept. of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha, Hunan, China Atipatsa C KAMINGA Dept. of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha, Hunan, China Aizhong LIU Dept. of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha, Hunan, China 2016 12 27 2016 12 27 Background: Prevalence estimates of Posttraumatic Stress Disorder (PTSD) among breast cancer patients varied widely in existing studies. This study aimed to provide an overall prevalence estimate of PTSD among breast cancer patients, and the prevalence estimates related to specific PTSD diagnosis tools. Methods: Systematic search of relevant articles was made from seven databases. Freeman-Tukey Double Arcsine Transformation was used to estimate the overall prevalence of PTSD. Sub-group and meta-regression analyses were used to investigate the between-study sources of heterogeneity. Publication bias was examined using Egger’s funnel plot and Begg test. Results: The pooled prevalence of PTSD among breast cancer patients was [9.6%, 95% confidence intervals (95%CI)=7.9-11.5%]. Studies that used Clinician Administered PTSD Scale-Form (CAPS) method alone yielded much higher prevalence (19.0%, 95%CI=13.1-25.5%, n=5) than three or fourth edition Structured Clinical Interview for Diagnostic and Statistical Manual (SCID) method alone (3.0%, 95%CI= 2.2-3.9%, n=11). Prevalence estimates for studies that used the methods: PTSD Checklist—Civilian Version (PCL-C) cut-off, PCL-C cluster, and Impact of Event Scale (IES) cut-off were (7.0%, 95%CI= 3.9-10.8%, n=10), (11.5%, 95%CI= 8.6-15.6%, n=11) and (15.1%, 95%CI= 12.3-18.2%, n=4), respectively. Heterogeneity between-study was substantial (I2=44.9–92.3%). Conclusion: About 9.6% of the breast cancer patients would develop the PTSD symptoms. Those who were younger, non-Caucasian and recently completed treatment would be at a greater risk of developing PTSD.   https://ijph.tums.ac.ir/index.php/ijph/article/view/8628 https://ijph.tums.ac.ir/index.php/ijph/article/download/8628/5397

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1652 1655 Arefeh KHADEMI Dept. of Neurology, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran Maryam POURSADEGHFARD Clinical Neurology Research Center, Dept. of Neurology, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran Reza NIKANDISH NOUBAR Dept. of Emergency Medicine, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran 2016 12 27 2016 12 27 Neurobrucellosis is uncommon; however, it is an important complication of brucellosis, which could be seen in any stage of the disease. It presents with different kinds of neurology manifestations and diagnosis is mainly made on history, physical examination and laboratory tests. The clinical course of the disease is relatively insidious and the most common pattern of presentation is subacute or chronic. It has a long-term treatment period and its response to treatment is slow. Here, we report a case of an apparent healthy 25 yr-old Afghani woman from Fars Province (south of Iran) that presented at first with hyperacute onset of headache and abnormal behavior and diagnosed neurobrucellosis in Nov 2015. In endemic areas, neurobrucellosis should be considered for each patient referred with unexplained neurological problems.   https://ijph.tums.ac.ir/index.php/ijph/article/view/8641 https://ijph.tums.ac.ir/index.php/ijph/article/download/8641/5484

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1656 1657 Weinan ZENG Dept. of Psychology, Research Center for Quality of Life and Applied Psychology, Guangdong Medical University, Donggguan, China Kaiyin YE Dept. of Psychology, School of Education, Guangzhou University, Guangzhou, China 2016 12 27 2016 12 27 Memory Self-efficacy Mediates the Relationship between Self-rated Health and Optimism among Chinese Older Adults https://ijph.tums.ac.ir/index.php/ijph/article/view/8652 https://ijph.tums.ac.ir/index.php/ijph/article/download/8652/5485

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1586 1594 Alessandro L. CAVALCANTI Dept. of Public Health, State University of Paraiba, Campina Grande, Brazil Ianny A. RAMOS Dept. of Dentistry, State University of Paraiba, Campina Grande, Brazil Andreia M. R. CARDOSO Dept. of Dentistry, State University of Paraiba, Campina Grande, Brazil Liege Helena F. FERNANDES Dept. of Dentistry, State University of Paraiba, Campina Grande, Brazil Amanda S. ARAGÃO Dept. of Dentistry, State University of Paraiba, Campina Grande, Brazil Fábio G. SANTOS Dept. of Dentistry, State University of Paraiba, Campina Grande, Brazil Yêska P. C. AGUIAR Dept. of Dentistry, State University of Paraiba, Campina Grande, Brazil Danielle F. CARVALHO Dept. of Public Health, State University of Paraiba, Campina Grande, Brazil Carla C. M. MEDEIROS Dept. of Public Health, State University of Paraiba, Campina Grande, Brazil Renata De S. C. SOARES Dept. of Public Health, State University of Paraiba, Campina Grande, Brazil Ricardo D. CASTRO Dept. of Clinics and Social Dentistry, Federal University of Paraiba, Joao Pessoa, Brazil 2016 12 27 2016 12 27 Background: Obesity is a serious problem of public health and affects all socio-economic groups, irrespective of age, sex or ethnicity. The aim of this study was to evaluate the association between periodontal condition and nutritional status of adolescents. Methods: This was a cross-sectional study using a probability cluster sampling, and the sample was defined by statistical criterion, consisting of 559 students aged 15-19 yr enrolled in public schools of adolescents of Campina Grande, PB, Brazil in 2012. Socioeconomic characteristics were analyzed, as well as self-reported general and oral health, anthropometric data and periodontal condition (CPI and OHI-S). Descriptive and analytical analysis from bivariate and multivariate Poisson regression analysis with 5% significance level was performed. Results: Of the 559 adolescents, 18.6% were overweight and 98.4% had some form of periodontal changes such as: bleeding (34.3%), calculus (38.8%), shallow pocket (22.9%) and deep pocket (2.3%). There was association between presence of periodontal changes with obesity (P<0.05; CI 95%: 0.99 [0.98 - 0.99]). Conclusion: The association between presence of periodontal changes and obesity status in adolescents was indicated.     https://ijph.tums.ac.ir/index.php/ijph/article/view/8633 https://ijph.tums.ac.ir/index.php/ijph/article/download/8633/5402

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1545 1557 Mohamed S. ZULFARINA Pharmaco-Epidemiology Unit, Dept. of Pharmacology, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia Ahmad M. SHARKAWI Pharmaco-Epidemiology Unit, Dept. of Pharmacology, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia Zaris-SM AQILAH-S.N Dept. of Orthopaedics, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Che-ras, Kuala Lumpur, Malaysia Sabarul-Afian MOKHTAR Dept. of Orthopaedics, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Che-ras, Kuala Lumpur, Malaysia Shuid A. NAZRUN Pharmaco-Epidemiology Unit, Dept. of Pharmacology, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia Isa NAINA-MOHAMED Pharmaco-Epidemiology Unit, Dept. of Pharmacology, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia 2016 12 27 2016 12 27 Background: This study conducted to examine and to provide a systematic literature over the influence of adolescents’ physical activity (PA) in maximizing`s peak bone mass (PBM). PBM or the ‘bone bank’ is an important determinant in achieving healthy bone. PA is one of the bone’s lifestyle contributors and high PBM is one of the major strategies for preventing osteoporosis. Methods: A computerized literature search using Medline (Ovid) and Scopus were conducted to identify relevant observational studies on the influence of different level of PA on bone acquisition among the healthy adolescent population. All articles included, were limited to original articles and English language. Results: Nine studies met the inclusion criteria. Reported bone outcomes were of bone mass, bone structure and bone strength. Eight studies showed positive association between adolescents’ PA and high bone variables. The influence of PA may differ according to sex, skeletal sites and bone outcomes. Conclusion: This study supported the importance of increase adolescents’ regular PA in optimizing PBM thus preventing osteoporosis at later life.   https://ijph.tums.ac.ir/index.php/ijph/article/view/8629 https://ijph.tums.ac.ir/index.php/ijph/article/download/8629/5398

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1658 1659 Aamir HUSSAIN Dept. of Community Medicine, Liaquat National Hospital & Medical College, Karachi, Pakistan 2016 12 27 2016 12 27 Rotavirus Vaccine Demand in Pakistan https://ijph.tums.ac.ir/index.php/ijph/article/view/8642 https://ijph.tums.ac.ir/index.php/ijph/article/download/8642/5486

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1595 1603 Mei HA School of Nursing, Chongqing Medical and Pharmaceutical College, Chongqing 400020, PR China Xiaoling QIAN The Second Hospital of Lanzhou University, Lanzhou, PR China Hong YANG School of Nursing, Chongqing Medical and Pharmaceutical College, Chongqing 400020, PR China Jichun HUANG School of Nursing, Chongqing Medical and Pharmaceutical College, Chongqing 400020, PR China Changjiang LIU Key Lab of Birth Defects and Reproductive Health of National Health and Family Planning Commission, Chongqing Population and Family Planning Science and Technology Research Institute, Chongqing 400020, PR China 2016 12 27 2016 12 27 Background: The public’s cognition of stroke and responses to stroke symptoms are important to prevent complications and decrease the mortality when stroke occurs. The aim of study was to develop and validate the Chinese version of the Stroke Action Test (C-STAT) in a Chinese population. Methods: This study was rigorously implemented with the published guideline for the translation, adaptation and validation of instruments for the cross-cultural use in healthcare care research. A cross-sectional study was performed among 328 stroke patients and family members in the Department of Neurology in the Second Hospital of Lanzhou University, Gansu province, China in 2014. Results: The Chinese version of the instrument showed favorable content equivalence with the source version. Values of Cronbach’s alpha and test-retest reliability of the C-STAT were 0.88 and 0.86, respectively. Principal component analysis supported four-factor solutions of the C-STAT. Criterion-related validity showed that the C-STAT was a significant predictor of the 7-item stroke symptom scores (R = 0.77; t = 21.74, P< 0.001). Conclusion: The C-STAT is an intelligible and brief psychometrical tool to assess individuals’ knowledge of the appropriate responses to stroke symptoms in Chinese populations. It could also be used by health care providers to assess educational programs on stroke prevention.   https://ijph.tums.ac.ir/index.php/ijph/article/view/8651 https://ijph.tums.ac.ir/index.php/ijph/article/download/8651/5403

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1558 1567 Joanna KRUK Dept. of Prevention and Occupational Therapy, Faculty of Physical Culture and Health Promotion, University of Szczecin, Szcze-cin, Poland Hassan ABOUL-ENEIN Dept. of Pharmaceutical and Medicinal Chemistry, Pharmaceutical and Drug Industries Research Division, National Research Center, Dokki, Giza, Egypt 2016 12 27 2016 12 27 Background: Prostate cancer (PCa) is the second most common malignancy in men worldwide. The purpose of this study was to provide a brief synthesis the current knowledge for the effects of physical activity (PA) and nutrition on PCa risk. Methods: A systematic review of English languages reviews, meta-analysis, and original articles published from 2009 to 2015 extracted from the following websites: MEDLINE, Web of Science, Health Source, Science Direct, and their references. Results: The review of the literature led to the selection of 12 review or meta-analysis studies and 15 lately published observational studies. Most of studies reported relationship of recreational and occupational PA and vegetables, fruits, vitamins, red/processed meats, and fats consumption with risk of PCa. Decreased risk for PCa associated with exercise was reported in seven of the ten articles on this topic. The inverse association of vegetables and/or fruit intake with PCa risk was reported in eight of 13 papers. The effect of meat/fat intake on PCa was estimated in four articles finding increased risk. There was heterogeneity between studies, and findings are inconsistent. Conclusion: Physical activity does not significantly reduce the risk of PCa; however, vigorous exercise may reduce the risk of aggressive tumor. Besides, there is a lack of definitive evidence supporting the preventive role of diet against PCa. Due to many other benefits of regular moderate-vigorous PA and a diet high in vegetables and fruits and low in red/processed meats and fats, these lifestyle patterns may be recommended.     https://ijph.tums.ac.ir/index.php/ijph/article/view/8630 https://ijph.tums.ac.ir/index.php/ijph/article/download/8630/5399

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1660 1661 Hua ZHANG Dept. of Medical Insurance, School of Public Health, Southeast University, Nanjing, Jiangsu, China Mingdong HUO Zhongda Hospital Affiliated to Southeast University, Nanjing, Jiangsu, China Jianqian CHAO Dept. of Medical Insurance, School of Public Health, Southeast University, Nanjing, Jiangsu, China Pei LIU Dept. of Epidemiology and Biostatistics, School of Public Health, Southeast University, Nanjing, Jiangsu, China 2016 12 27 2016 12 27 Willing to Pay for Antiviral Treatment of Hepa¬titis B Patients https://ijph.tums.ac.ir/index.php/ijph/article/view/8643 https://ijph.tums.ac.ir/index.php/ijph/article/download/8643/5487

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1604 1609 Min LI Dept. of Thoracic Surgery, Xuzhou Central Hospital Affiliated to Southeast University, Jiangsu, Xuzou 221009, People’s Republic of China Miao ZHANG Dept. of Thoracic Surgery, Xuzhou Central Hospital Affiliated to Southeast University, Jiangsu, Xuzou 221009, People’s Republic of China Heng WANG Dept. of Thoracic Surgery, Xuzhou Central Hospital Affiliated to Southeast University, Jiangsu, Xuzou 221009, People’s Republic of China Xuefeng PAN Dept. of Thoracic Surgery, Xuzhou Central Hospital Affiliated to Southeast University, Jiangsu, Xuzou 221009, People’s Republic of China Wenbin WU Dept. of Thoracic Surgery, Xuzhou Central Hospital Affiliated to Southeast University, Jiangsu, Xuzou 221009, People’s Republic of China Qi ZHANG Dept. of Thoracic Surgery, Xuzhou Central Hospital Affiliated to Southeast University, Jiangsu, Xuzou 221009, People’s Republic of China Yun LIU Dept. of Thoracic Surgery, Xuzhou Central Hospital Affiliated to Southeast University, Jiangsu, Xuzou 221009, People’s Republic of China Hui ZHANG Dept. of Thoracic Surgery, Xuzhou Central Hospital Affiliated to Southeast University, Jiangsu, Xuzou 221009, People’s Republic of China 2016 12 27 2016 12 27 Background: The objective of the present study was to explore the efficacy of internet-based intervention on quality of life of patients with chronic post-surgical pain (CPSP).   Methods: A retrospective analysis was performed on 81 patients diagnosed with CPSP after radical resection for lung cancer between January 2013 and July 2014.  They were enrolled either as part of the conventional care group which included 40 cases or the internet-based pain intervention group which included 41 cases. The patients in the conventional care group were treated weekly in the outpatient clinic, while patients in internet-based group were treated via smartphone or the internet.  The 36-Item Short Form Health Survey (SF-36) was utilized to assess the quality of life of patients who were suffering from CPSP, 1 month and 3 months after therapy. Results: The patients in the internet-based pain intervention group demonstrated similar health-related qualities of life and overall satisfaction rates compared with the conventional care group (P>0.05). Conclusion: Internet-based pain management is a suitable option to improve the quality of life of patients with CPSP after radical resection for lung cancer.   https://ijph.tums.ac.ir/index.php/ijph/article/view/8634 https://ijph.tums.ac.ir/index.php/ijph/article/download/8634/5404

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1568 1576 Somaye YOSAEE Dept. of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran AND Ewaz School of Health, Larestan School of Medical Sciences, Larestan, Iran Sepideh SOLTANI Dept. of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran Eghbal SEKHAVATI Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Shima JAZAYERI Dept. of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran AND Research Center for Prevention of Cardiovascular Disease, Iran University of Medical Sciences, Tehran, Iran 2016 12 27 2016 12 27 Background: Heart disease is one of the most common chronic disease and leading cause of morbidity and mortality worldwide. Adropin, a newly identified protein, is important for energy homeostasis and maintaining insulin sensitivity, and has been referred to as a novel regulator of endothelial cells. Endothelial dysfunction is a key early event in atherogenesis and onset of HD. Therefore, this review gives a systematic overview of studies investigating plasma adropin level in patient with heart disease. Methods: Data carried out in PubMed, Scopus, Web of Science, Embase, Google scholar and MEDLINE, from the earliest available online indexing year through 2015. The search restricted to studies conducted in humans. The keyword search was adropin to apply in title, abstract and keywords. References lists of all original published articles were scanned to find additional eligible studies. Results: Heart failure (HF), coronary atherosclerosis acute myocardial infarction and Cardiac Syndrome X (CSX) were type of heart disease acknowledged in this study. Majority of evidences introduced low adropin as an independent risk factor of heart disease. In a case-control study, the plasma level of adropin increased with the severity of HF. Conclusion: Adropinmay be a potential serum biomarker for early diagnosis of HD.   https://ijph.tums.ac.ir/index.php/ijph/article/view/8631 https://ijph.tums.ac.ir/index.php/ijph/article/download/8631/5400

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1662 1664 Mahtab KARAMI Dept. of Health Information Technology and Management, School of Allied Medical Sciences, Kashan University of Medical Sciences, Kashan, Iran Nasrin HAFIZI Dept. of Health Information Technology and Management, School of Allied Medical Sciences, Kashan University of Medical Sciences, Kashan, Iran 2016 12 27 2016 12 27 E-game in Healthcare: As an E-intervention to Promote Public Health https://ijph.tums.ac.ir/index.php/ijph/article/view/8644 https://ijph.tums.ac.ir/index.php/ijph/article/download/8644/5488

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1610 1617 Davoud AFSHAR Dept. of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mohammad Reza POURMAND Dept. of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran Mahmood JEDDI-TEHRANI Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR, Tehran, Iran Ali Akbar SABOOR YARAGHI Dept. of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mohammad AZARSA Dept. of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Fazel SHOKRI Dept. of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2016 12 27 2016 12 27 Background: Choline-binding proteins (CBPs) are a group of surface-exposed proteins, which play crucial and physiological roles in Streptococcus pneumoniae. The novel member of CBPs, choline-binding protein M (CbpM) may have binding activity to plasma proteins. This study aimed to clone and express CbpM and demonstrate its interaction with plasma proteins and patients’ sera. Methods: The total length of cbpM gene was cloned in pET21a vector and expressed in BL21 expression host. Verification of recombinant protein was evaluated by Western blot using anti-His tag monoclonal antibody. Binding ability of the recombinant protein to plasma proteins and the interaction with patients’ sera were assessed by Western blot and ELISA methods. Results: The cbpM gene was successfully cloned into pET21a and expressed in BL21 host. Binding activity to fibronectin and fibrinogen and antibody reaction of CbpM to patients’ sera was demonstrated by Western blot and ELISA methods, respectively. Conclusion: CbpM is one of the pneumococcal surface-exposed proteins, which mediates pneumococcal binding to fibronectin and fibrinogen proteins.   https://ijph.tums.ac.ir/index.php/ijph/article/view/8636 https://ijph.tums.ac.ir/index.php/ijph/article/download/8636/5479

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1665 1666 Jannan GHAPANCHI Dept. of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran Fahimeh REZAZADEH Dept. of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran Erfan FAKHRAEE School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran Aisa ZAMANI 3.Student Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran 2016 12 27 2016 12 27 Prevalence of Xerostomia in Patients Referred to Shiraz Dental School, Shiraz, Iran during 2006-2013 https://ijph.tums.ac.ir/index.php/ijph/article/view/8645 https://ijph.tums.ac.ir/index.php/ijph/article/download/8645/5489

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1618 1624 Maryam Beigom MOBASHERI Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran AND Dept. of Medical Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran Reza SHIRKOOHI Dept. of Medical Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran Mohammad Hossein MODARRESSI Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran AND Dept. of Medical Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran 2016 12 27 2016 12 27 Background: Breast cancer is the most frequent cancer in women. Cancer/Testis antigens are immunogenic proteins ectopically expressed in human neoplasms. Synaptonemal complex protein 3 (SYCP3) belongs to cancer/testis genes family involved in meiotic events and spermatogenesis. The aim of this study was to express analysis of SYCP3 in breast cancer and validate it as a breast cancer biomarker. Methods: Expression of SYCP3 transcripts in 47 breast tumors, 6 breast cancer cell lines (MCF7, SKBR3, T47D, BT474, MDA-MB-231 and MDA-MB 468), 5 normal breast and 2 testis tissues was studied by Real Time RT-PCR reaction. The reference genes phosphoglucomutase 1 and hypoxanthine guanine phosphoribosyl transferase were used as reactions normalizers. The software tool REST 2009 was applied for statistical analysis of the data. The research was conducted from Apr 2014 to August 2015 in Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Results: All of the studied breast cancer cell lines showed very high levels of SYCP3 overexpression in comparison to normal breast (P=0.001) and even to normal testis (P=0.001), except for MCF7 cell line. Breast tumors showed moderately increasing in transcript changes in comparison to normal breast. Conclusion: SYCP3 is a known testis-specific gene, but interestingly five out of six studied breast cancer of cell lines showed higher expression levels of SYCP3 in comparison to normal testis and normal breast tissues. SYCP3 has critical role in cell division with known interaction with the tumor suppressor genes, BRCA1 and BRCA2, which are critical genes in breast cancer.   https://ijph.tums.ac.ir/index.php/ijph/article/view/8637 https://ijph.tums.ac.ir/index.php/ijph/article/download/8637/5480

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 12 2016 12 27 1667 1668 Shahram SAVAD Dept. of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Sepideh HAMZEHLOU Dept. of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Jila GHAFFOURIAN ABADI Dept. of Obstetrics and Gynecology, Kamali Hospital, Alborz University of Medical Sciences, Karaj, Iran Mohammad Hossein MODARRESSI Dept. of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Shahab NOORIAN Dept. of Pediatric Endocrinology and Metabolism, Bahonar Hospital, Alborz University of Medical Sciences, Karaj, Iran 2016 12 27 2016 12 27 Dizygotic Twins Concordant for Down Syndrome: Implication for Establishing a National Birth Defect Registry in Iran https://ijph.tums.ac.ir/index.php/ijph/article/view/8646 https://ijph.tums.ac.ir/index.php/ijph/article/download/8646/5495

Guilan Road Trauma Research Center (GRTRC), Guilan University of Medical Sciences, Rasht, Iran Kazem ZENDEHDEL Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran Amir AZARHOMAYOUN Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran Khatereh NAGHDI Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran Gerard OREILLY Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia Ellen MERETE 1. Autonomic Unit, National Hospital for Neurology & Neurosurgery, Queen Square, London, UK 2. Institute of Neurology, University College London, London, UK Alexander R Vaccaro Department of Orthopaedic Surgery, The Rothman Institute, Thomas Jefferson University, Philadelphia, USA Edward C BENZEL Cleveland Clinic Foundation, Department of Neurosurgery, Cleveland, Ohio, USA Seyed Behzad JAZAYERI Department of Urology, University of Florida, Jacksonville, FL, USA Vafa RAHIMI-MOVAGHAR Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran AND Brain and Spinal Cord Injury Research Center, Neurosciences Institute, Tehran University of Medical Sciences, Tehran, Iran 2018 06 11 2018 10 08 Background: The National Traumatic Spinal Cord Injury Registry in Iran (NSCIR-IR), was implemented initially in three hospitals as a pilot phase from 11 Oct 2015 to 19 Jun 2016 and has been active in eight centers from 19 Jun 2016. Poursina Hospital, a trauma care referral center in Rasht, Guilan Province of Iran is one of the registry sites, and has been involved in registering eligible patients since 1 Jan 2016. This study aimed to identify the challenges and solutions for sustaining the NSCIR-IR in a regional center. Methods: This was a mixed-methods study. For the quantitative analysis, a retrospective observational design was used to measure case capture or case identification rate, mapping cases in the registry against those eligible for registry inclusion amongst the register of hospital admissions. For the qualitative component, data was collected using focus group discussions and semi-structured interviews, followed by thematic analysis. Results: From 19 Jun 2016 to 24 Jan 2018, the proportion of case capture (case identification rate) was 17%. The median time between case identification and data entry to the system was 30.5 d (range: 2 to 193 d). Thematic analysis identified a lack of trained human resources as the most important cause of low case identification rate and delay in data completion. Conclusion: Recruitment and education to increase trained human resources are needed to improve case capture, the timeliness of data input and registry sustainability in a regional participating site. https://ijph.tums.ac.ir/index.php/ijph/article/view/13682 https://ijph.tums.ac.ir/index.php/ijph/article/download/13682/6888

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 4 2020 04 01 744 752 EN Younes MOHAMMADI Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran AND Social Determinants of Health Research Center, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran Manoochehr KARAMI Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran AND Modelling of Noncommunicable Diseases Research Center, Hamadan University of Medical Sciences, Hamadan, Iran Nasrin DERAKHSHANZADEH Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran AND Students Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran 2018 04 05 2018 08 27 Background: To estimate under-five mortality rate (U5MR), as one of the sustainable development goals, in rural and urban areas of Iran from 1990 to 2015. Methods: We used the data collected through two censuses and one Demographic and Health Surveys (DHS). We analyzed the Summary Birth History (SBH) data via 2 approaches including Maternal Age Cohort (MAC) and Maternal Age Period (MAP) methods, and then, Gaussian Process Regression (GPR) was used to combine the three trends and with 95% uncertainty. Finally, Ratio of U5MR in rural to urban was calculated. Results: At the national level and in urban areas, U5MR in 1990, 2000, 2010, and 2015 was 66, 34, 18, and 13 per 1000 live births, respectively. Corresponding values in rural areas in 1990, 2000, 2010, and 2015 was 129, 64, 31, and 21 per 1000 live births, respectively. Accordingly, the ratio of U5MR in rural to urban at the national level was 1.93, 1.86, 1.72 and 1.63 in the same years. At the sub-national level, U5MR in urban areas ranged from 11.2 per 1000 live births in Isfahan to 18.2 per 1000 live births in Hormuzagn. U5MR in rural areas ranged from 14.1 per 1000 live births in Isfahan to 29.5 per 1000 live births in Sistan and Baluchistan Conclusion: There is still a gap between rural and urban areas, although it has decreased during the 25 years of the study. To alleviate this gap, health system authorities are advised to plan appropriate actions using multi-sectoral capacities. https://ijph.tums.ac.ir/index.php/ijph/article/view/12967 https://ijph.tums.ac.ir/index.php/ijph/article/download/12967/6889

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 4 2020 04 01 753 762 EN Narges AHANI Department of Biology, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, Iran Mohammad Hossein SANGTARASH Department of Biology, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, Iran Majid ALIPOUR ESKANDANI Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Zabol, Zabol, Iran Massoud HOUSHMAND Department of Medical Genetics, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran AND Research Center, Knowledge University, Erbil, Kurdistan Region, Iraq 2018 01 29 2018 08 27 Background: Zataria multiflora Boiss. is known by the common Persian name “Avishan-e-Shirazi”, is one of the best-known medicinal herbs belonging to the Labiatae (Lamiaceae) family. The aim of this study was to evaluate the anticancer effects and the underlying mechanisms of how Z. multiflora Boiss., essential oil induced apoptosis in the human colorectal tumor cell lines (HCT116 & SW48). Methods: This study was conducted in National Institute of Genetic Engineering and Biotechnology (NIGEB) (Tehran, Iran) from 2017 to 2019.  The cytotoxicity of this essential oil was assessed by 3- (4,5-di-methylthiazol-2-yl)- 2,5-diphenyltetra-zolium bromide (MTT) assay, trypan blue exclusion, and colony formation assays. We assessed apoptosis and measure intracellular reactive oxygen species (ROS) by flow cytometry. Then gene expression was analyzed by Quantitative Real-Time RT-PCR. Results: Z. multiflora Boiss., essential oil time- and dose-dependently inhibits cell proliferation and also induced apoptosis in both cell lines via UCP2-related mitochondrial pathway by the induction of intracellular ROS. Conclusion: Z. multiflora Boiss., essential oil could be a good candidate for use as an inhibitor of the growth of colorectal tumor cells. https://ijph.tums.ac.ir/index.php/ijph/article/view/12366 https://ijph.tums.ac.ir/index.php/ijph/article/download/12366/6890

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 4 2020 07 20 763 772 Mostafa EGHBALIAN Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran Abbas MOGHIMBEIGI Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran AND Modeling of Noncommunicable Disease Research Center, Hamadan University of Medical Sciences, Hamadan, Iran Marzieh MAHMOODI Department of Biostatistics, Faculty of Health and Nutrition, Bushehr University of Medical Sciences, Bushehr, Iran Iraj MOHAMADFAM Department of Occupational Health, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran Razieh Sadat MIRMOEINI Disease Control & Prevention Center, Deputy of Health Services, Hamadan University of Medical Sciences, Hamadan, Iran 2020 03 28 Background: Accidents were just one of the general health problems. According to WHO forecasts (2013), deaths from road accidents will become the fifth-highest cause of death in the world by 2030. Therefore, we have attempted the application of non-parametric count models for modeling female’s accident rates. Methods: All accidents in Hamadan Province, western Iran are referred to as one of the emergency centers located in the hospitals. Data regarding the accidents were obtained from 21 emergency centers across Hamadan for the period 2009-2016. To assess the trend and pattern of the accidents, the Generalized Additive Model for the accident rate has been utilized. Results: The Mean±SD age of the females in study was 31.23±12.88 yr old. For each of the three kinds of road accidents (car accidents, motor accidents and pedestrian crashes), the accident rates in the “residential urban” areas are lesser than in the “non-residential” area (P=<0.001) and in "public and sports grounds" and "great roads, avenues and streets" are more than in "others". For the three kinds of accidents, the functional effect in the monthly trend of the accidents was signification (P=<0.001). Conclusion: The rates for all three kinds of accidents decreased. The increase in accident rates from the beginning of 2014 to Mar 2016 maybe due to the generalization of insurances in Iran and the increase in the number of accident victims being referred to the hospitals, which was the same with the results of other studies.   https://ijph.tums.ac.ir/index.php/ijph/article/view/20169 https://ijph.tums.ac.ir/index.php/ijph/article/download/20169/6738

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 4 2020 04 01 773 781 EN Hamid Reza TABATABAEE Research Center for Health Sciences, Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran Atefeh ZAHEDI Department of Public Health, School of Health, Abadan School of Medical Sciences, Abadan, Iran Koorosh ETEMAD Department of Epidemiology, Environmental and Occupational Hazards Control Research Center, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran Tannaz VALADBEIGI Clinical Research Development Unit, Imam Hossein Hospital, Shahroud University of Medical Sciences, Shahroud, Iran Sepideh MAHDAVI Department of Epidemiology, School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran Mostafa ENAYATRAD Department of Epidemiology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran