Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 289 296 Pedro GIRON Dept. of Estadística e Investigación Operativa III, Facultad de Estudios Estadísticos, Universidad Complutense de Madrid, Madrid, Spain 2016 03 15 2016 03 15 Background: To analyse time trends in self-rated health in older people by gender and age and examine disability in the time trends of self-rated health. Methods: The data used come from the Spanish National Health Surveys conducted in 2001, 2003, 2006 and 2011-12. Samples of adults aged 16 yr and older were selected. Multivariate logistic regression was used to assess the association between age, gender, socio-economic status, marital status, disability and self-rated health across period study. Results: Women exhibited lower (higher) prevalence of good self-rated health (disability) compared to men. The multivariate analysis for time trends found that good self-rated health increased from 2001 to 2012. Overall, variables associated with a lower likelihood of good self-rated health were: being married or living with a partner, lower educational level, and disability. Conclusion: Trends of good self-rated health differ by gender according to socio-demographic factors and the prevalence of disability.   https://ijph.tums.ac.ir/index.php/ijph/article/view/6260 https://ijph.tums.ac.ir/index.php/ijph/article/download/6260/5321

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 278 288 Javad MOGHRI Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mohammad ARAB Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Arash RASHIDIAN Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Ali AKBARI SARI Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2016 03 15 2016 03 15 Background: Physician dual practice is a common phenomenon in almost all countries throughout the world, which could potential impacts on access, equity and quality of services. This paper aims to review studies in physician dual practice and categorize them in order to their main objectives and purposes. Methods: Comprehensive literature searches were undertaken in order to obtain main papers and documents in the field of physician dual practice. Systematic searches in Medline and Embase from 1960 to 2013, and general searches in some popular search engines were carried out in this way. After that, descriptive mapping review methods were utilized to categorize eligible studies in this area. Results: The searches obtained 404 titles, of which 81 full texts were assessed. Finally, 24 studies were eligible for inclusion in our review. These studies were categorized into four groups - "motivation and forces behind dual practice", "consequences of dual practice", "dual practice Policies and their impacts", and "other studies" - based on their main objectives. Our findings showed a dearth of scientifically reliable literature in some areas of dual practice, like the prevalence of the phenomenon, the real consequences of it, and the impacts of the implemented policy measures. Conclusion: Rigorous empirical and evaluative studies should be designed to detect the real consequences of DP and assess the effects of interventions and regulations, which governments have implemented in this field.     https://ijph.tums.ac.ir/index.php/ijph/article/view/6259 https://ijph.tums.ac.ir/index.php/ijph/article/download/6259/5320

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 370 375 Shokouh Azam SARRAFZADEH Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran Maryam MAHLOOJIRAD Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran Maryam NOURIZA­DEH Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran Jean-Laurent CASANOVA Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale, INSERM-U1163, Paris, France AND Howard Hughes Medical Institute, NY, USA AND Paris Descartes University, Imagine Institute, Paris, France AND Center for the Study of Primary Immunodeficiencies, Necker Hospital for Sick Children, AP-HP, Paris, France AND St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller branch, the Rockefeller University, New York, NY, USAPediatric Hematology-Immunology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France Zahra POURPAK Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran Jacinta BUSTAMANTE Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale, INSERM-U1163, Paris, France AND Paris Descartes University, Imagine Institute, Paris, France AND Center for the Study of Primary Immunodeficiencies, Necker Hospital for Sick Children, AP-HP, Paris, France AND St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller branch, the Rockefeller University, New York, NY, USA Mostafa MOIN Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran 2016 03 15 2016 03 15   Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare inheritance syndrome, characterized by a disseminated infection with mycobacterium in children following BCG vaccination at birth. Regarding the vaccination program in Iran, it may consider as a public health problem. The pathogenesis of MSMD is dependent on either insufficient production of IFN-gamma (γ) or inadequate response to it. Here, we want to introduce three cases including two siblings and one girl from two unrelated families with severe mycobacterial infections referred to Immunology, Asthma and Allergy Research Institute (IAARI), from 2013 to 2015; their MSMD was confirmed by both cytokine assessment and genetic analysis. Regarding the clinical features of the patients, cell proliferation against a mitogen and BCG antigen was ordered in a lymphocyte transformation test (LTT) setting. ELISA was performed for the measurement of IL-12p70 and IFN- γ in whole blood samples activated by BCG + recombinant human IFN-γ and BCG + recombinant human IL-12, respectively. In contrast to mitogen, the antigen-dependent proliferation activity of the patients’ leukocytes was significantly lower than that in normal range. We identified a homozygous mutation in IL12RB1 gene for two kindred who had a homozygous mutation affecting an essential splice site. For the third patient, a novel frameshift deletion in IL12RB1 gene was found. The genetic study results confirmed the impaired function of stimulated lymphocytes to release IFN-γ following stimulation with BCG+IL-12 while the response to rhIFN-γ for IL-12p70 production was relatively intact. Our findings show that cellular and molecular assessments are needed for precise identification of immunodeficiency disorders especially those without clear-cut diagnostic criteria.     https://ijph.tums.ac.ir/index.php/ijph/article/view/6270 https://ijph.tums.ac.ir/index.php/ijph/article/download/6270/5333

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 387 389 Seongeon KIM Dept. of Physical Education, Sejong University, Seoul, Korea Jooyoung KIM Health and Rehabilitation Major, Kookmin University, Seoul, Korea Yongsoo LEE Dept. of Physical Education, Sejong University, Seoul, Korea Min Keun SEO Division of Sport Science, Konkuk University, Choong Ju, Korea Dong Jun SUNG Division of Sport Science, Konkuk University, Choong Ju, Korea 2016 03 15 2016 03 15 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/6273 https://ijph.tums.ac.ir/index.php/ijph/article/download/6273/5336

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 297 304 Yongqing GAO School of Food Sciences, Guangdong Pharmaceutical University, Zhongshan, China Chunsheng CAI School of Food Sciences, Guangdong Pharmaceutical University, Zhongshan, China Jian LI School of Public Health and Tropical Medicine, Tulane University, New Orleans, USA Wenjie SUN School of Food Sciences, Guangdong Pharmaceutical University, Zhongshan, China AND School of Public Health and Tropical Medicine, Tulane University, New Orleans, USA 2016 03 15 2016 03 15 Background: To examine the effect of nutritional education on children’s breakfast patterns Methods: A kindergarten based nutrition intervention was started in September 2001 among 8 kindergartens in Hefei with a total of 2,012 children aged 4-6 years and their parent pairs. Results: Monthly nutrition education sessions were held over two semesters in kindergartens part of the intervention arm.  The approach in education and the content of other activities were uniform across all the kindergartens. A validated questionnaire was used to record breakfast behavior over 7 days including at least one weekend. The parents recorded the children’s breakfast pattern (frequency, time, and food selection) at baseline, middle, and end of the study. After intervention, there were significant differences at the final stage, but none at the baseline before intervention. There were changes not only in breakfast frequency, but also in the breakfast selection Conclusion: The breakfast pattern of Chinese children can be modified through nutrition education after a long term intervention.   https://ijph.tums.ac.ir/index.php/ijph/article/view/6261 https://ijph.tums.ac.ir/index.php/ijph/article/download/6261/5322

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 376 380 Mohammad Yahya VAHIDI MEHRJARDI Medical Genetics Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AND Dept. of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Masoud DEHGHAN TEZERJANI Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mahmoud NORI-SHADKAM Dept. of Pediatrics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Seyed Mehdi KALANTAR Dept. of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AND Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mohammadreza DEHGHANI Medical Genetics Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AND Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 2016 03 15 2016 03 15 The interpretation of supernumerary chromosome is important for genetic counseling and prognosis. Here, we used SNP array and conventional karyotyping method to identify a denovo marker chromosome originated from chromosome 22 and 11 in a newborn transferred to the Neonatal Intensive Care Unit of Shahid Sadoughi Hospital in 2015.  Clinical abnormalities identified in the newborn were dysmorphic face, intrauterine growth retardation, atrial septal defect (ASD), the hypoplasia of corpus callosum and septum pellucidum. These clinical abnormalities can be related to this marker, and it may help genetic counselor for predicting abnormality risk in susceptible individuals as well as prenatal diagnosis.    https://ijph.tums.ac.ir/index.php/ijph/article/view/6271 https://ijph.tums.ac.ir/index.php/ijph/article/download/6271/5334

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 390 391 Peng QUAN Guangdong Medical University, Dongguan, China Dan HUANG Guangdong Women’s Polytechnic College, Guangzhou, China Yulan YU Guangdong Medical University, Dongguan, China Ruiming LIU Guangdong Medical University, Dongguan, China 2016 03 15 2016 03 15 No Abstract. https://ijph.tums.ac.ir/index.php/ijph/article/view/6274 https://ijph.tums.ac.ir/index.php/ijph/article/download/6274/4652 https://ijph.tums.ac.ir/index.php/ijph/article/download/6274/5337

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 305 313 Dursun TATAR 1. Dept. of Pulmonary Diseases, Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir, Turkey Gunes SENOL Dept. of Infectious Diseases and Clinical Microbiology, Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir Turkey Serpil ALPTEKIN Dept. of Pulmonary Diseases, Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir, Turkey Ebru GUNES Dept. of Pulmonary Diseases, Dr. Suat Seren Chest Diseases and Surgery Training and Resjph.tums.ac.ir/index.php/ijph/article/download/10989/5675

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 9 2017 09 03 1297 1298 Seung-Won YANG College of Education, Hankuk University of Foreign Studies, Seoul, Korea Se-Jeong KWON College of Sport Sciences, Chung-Ang University, Ansung, Korea Joon-Sung PARK Division of Wellbeing Physical Education, Silla University, Pusan, Korea Tae-Young KIM College of Education, Hankuk University of Foreign Studies, Seoul, Korea Nam-Il AN Division of Culture Creativity, Korea University, Sejong, Korea Young-Sub LEE Asia Contents Institute, Konkuk University, Seoul, Korea 2017 09 03 2017 09 03 Influence of Youth Baseball Players’ Pitches on Range of Motion and Ball Speed https://ijph.tums.ac.ir/index.php/ijph/article/view/11008 https://ijph.tums.ac.ir/index.php/ijph/article/download/11008/5694

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 9 2017 09 03 1211 1216 Xiangyu CHEN Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, P.R. China Le FANG Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, P.R. China Hongbo LIN Yinzhou District Center for Disease Control and Prevention, Ningbo, P.R. China Peng SHEN Yinzhou District Center for Disease Control and Prevention, Ningbo, P.R. China Tao ZHANG Ningbo Municipal Center for Disease Control and Prevention, Ningbo, P.R. China Hui LI Ningbo Municipal Center for Disease Control and Prevention, Ningbo, P.R. China Xiaoyong LI Yinzhou District Center for Disease Control and Prevention, Ningbo, P.R. China Min YU Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, P.R. China Chunxiao XU Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, P.R. China Jie ZHANG Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, P.R. China Feng LU Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, P.R. China Xiaofu DU Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, P.R. China Ruying HU Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, P.R. China Jieming ZHONG Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, P.R. China 2017 09 03 2017 09 03 Background: Currently, the studies on the relationship between type 2 diabetes and platelets indicators were carried out on a selective small sample population generally. Large sample studies in this area are rare, especially in Chinese population. In this study, we aimed to investigate the relationship between type 2 diabetes and the mean platelet volume (MPV), platelet count (PLT) and platelet distribution width (PDW). Methods: This is a cross-sectional analysis of the routine health examination data from 20128 participants with complete baseline data in Yinzhou District 2013. The detection of indicators in this study was completed by automatic hematology analyzer. Results: The PDW and PLT were not significantly different between diabetic group and non-diabetic group, (16.00% vs. 16.00%, P=0.88, and 194*109/L vs. 196*109/L, P=0.05 respectively). The MPV was significantly higher in diabetic group (9.3fl vs. 9.2fl, P<0.05). MPV was an independent risk factor of diabetes mellitus (Unadjusted OR=1.07 (95% CI: 1.03, 1.11), Adjusted for age, sex OR=1.07 (95% CI: 1.02, 1.12)). The adjusted odds ratio of diabetes rose with increasing MPV levels and were most pronounced in subjects with MPV levels exceeding the 90th percentile (MPV≥10.70 fl, Crude or=1.23 adjusted or=1.19). Conclusion: There was no relationship between the presence of diabetes with PDW and PLT. The MPV was independently associated with the presence of diabetes.   https://ijph.tums.ac.ir/index.php/ijph/article/view/10993 https://ijph.tums.ac.ir/index.php/ijph/article/download/10993/5679

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 9 2017 09 03 1299 1300 Salah ABERKANE Dept. of Psychology, Faculty of Human and Social Sciences, Khenchela University, Khenchela, Algeria 2017 09 03 2017 09 03 Perceived Health Related Quality of Life Outcomes with Silicosis Patients https://ijph.tums.ac.ir/index.php/ijph/article/view/11009 https://ijph.tums.ac.ir/index.php/ijph/article/download/11009/5695

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 9 2017 09 03 1217 1222 Qinghui KONG Dept. of Ophthalmology, Shenzhen Second Hospital, Shenzhen, Guangdong, China Jiang GUO Dept. of Ophthalmology, Shenzhen Second Hospital, Shenzhen, Guangdong, China Jing ZHOU Dept. of Ophthalmology, Shenzhen Second Hospital, Shenzhen, Guangdong, China Yanling ZHANG Dept. of Teaching and Research, School of Medical Technology and Nursing, Shenzhen, Guangdong, China Xiaoyan DOU Dept. of Ophthalmology, Shenzhen Second Hospital, Shenzhen, Guangdong, China 2017 09 03 2017 09 03 Background: We aimed to identify factors influencing the therapeutic outcome of orthokeratology on controlling juvenile myopia progression, and the risk factors for complications. Methods: Myopic patients (n=724) in Shenzhen Second Hospital from Jan 2011 to Jan 2016 fitted with orthokeratology lenses and followed-up for 6–65 months were reviewed retrospectively. Univariate and multivariate logistic regression analyses were used to screen for the factors that can improve treatment outcome and prevent the development of complications. Results: Patients where the orthokeratology treatment was effective displayed a shorter myopia time, smaller diopter and corneal curvature, larger corneal endothelium density, high proportion of overnight wear and longer wearing times compared with patients whose treatments were ineffective. Additionally, wearing Ortho-k for 6 or 12 months yielded improved corrective effect and achieved higher comfort level. Logistic regression analyses showed that myopia time, diopter, corneal curvature e value, corneal endothelium density, time with Ortho-k and corrective effect after wearing Ortho-k for 6 or 12 months were all independent factors influencing the treatment effects. Results showed corneal curvature, anterior chamber depth and central corneal thickness were independent risk factors. Conclusion: This study systematically identified the factors leading to effective treatments, and those carrying a risk for complications, to provide guidance for the prescription and follow-up of orthokeratology in the treatment of juvenile myopia.     https://ijph.tums.ac.ir/index.php/ijph/article/view/10994 https://ijph.tums.ac.ir/index.php/ijph/article/download/10994/5680

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 9 2017 09 03 1301 1302 Mohammed ALBASHTAWY Community and Mental Health Department, Princess Salma Faculty of Nursing, AL al-Bayt University, Mafraq, Jordan 2017 09 03 2017 09 03 Pediculosis in School Sitting: What Is the Role of School Nurses? https://ijph.tums.ac.ir/index.php/ijph/article/view/11010 https://ijph.tums.ac.ir/index.php/ijph/article/download/11010/5696

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 9 2017 09 03 1223 1230 Yinhua ZHANG Dept. of Community Nursing, School of Nursing, Central South University, Changsha, P.R. China AND Dept. of Fundamentals of Nursing, School of Nursing, Hunan University Traditional Chinese Medicine, Changsha, P.R. China Qun YUAN Dept. of Fundamentals of Nursing, School of Nursing, Hunan University Traditional Chinese Medicine, Changsha, P.R. China Xia YI Dept. of Fundamentals of Nursing, School of Nursing, Hunan University Traditional Chinese Medicine, Changsha, P.R. China Honghua LIU Dept. of Fundamentals of Nursing, School of Nursing, Hunan University Traditional Chinese Medicine, Changsha, P.R. China Xiaoyan PAN Dept. of Fundamentals of Nursing, School of Nursing, Hunan University Traditional Chinese Medicine, Changsha, P.R. China Jingwei LIU Medical Insurance Bureau of Hunan Province, Changsha, P.R. China Yi XU Dept. of Fundamentals of Nursing, School of Nursing, Hunan University Traditional Chinese Medicine, Changsha, P.R. China Yang CHEN Dept. of Fundamentals of Nursing, School of Nursing, Hunan University Traditional Chinese Medicine, Changsha, P.R. China Guoping HE Dept. of Fundamentals of Nursing, School of Nursing, Hunan University Traditional Chinese Medicine, Changsha, P.R. China 2017 09 03 2017 09 03 Background: China had implemented policies to limit antimicrobials prescription since 2004; we conducted this study to reflect the effect of these national policies by analyzing antimicrobial prescription trends of medical insurance in patients from 2003 to 2014 in Changsha city, China. Methods: The participants were inpatients of the medical insurance of urban workers (UEBMI). Data were extracted from medical insurance information system of Changsha Medical Insurance Institution, which directly connects with hospitals information systems. Results: Trend analysis showed great changes in antimicrobial prescription and inpatients’ cost on antimicrobials over the study period. Antimicrobial prescription rates gradually declined over the study period from 79.0% in 2003 to 43.5% in 2014 (adjusted OR0.205; 95%CI 0.198 to 0.213). There was a quicker decline from 2011 to 2014 (with implementing national antimicrobial stewardship action plan) than the period from 2003 to 2010 (with implementing antimicrobials use education and self-management strategies). The proportion of inpatients used one antimicrobial increased significantly from 25.6% in 2003 to 46.7% in 2014, while the proportion of inpatients used three or more antimicrobials gradually decreased. Bacterial culture rate increased from 20.4% in 2003 to 36.6% in 2014 (adjusted OR 2.248; 95% CI 2.149 to 2.352). The average costs on antimicrobials decreased significantly, from 277.43 US Dollar in 2003 to 91.05 US Dollar in 2014. Conclusion: National efforts to promote rational use of antimicrobials in clinical practice have had a positive effect over the past decade in China.     https://ijph.tums.ac.ir/index.php/ijph/article/view/10995 https://ijph.tums.ac.ir/index.php/ijph/article/download/10995/5681

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 9 2017 09 03 1303 1304 Aziz KASSANI Dept. of Community Medicine, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran Abdolvahab BAGHBANIAN Health Systems and Global Populations, Faculty of Health Sciences, University of Sydney, Sydney, Australia Walieh MENATI Prevention of Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran 2017 09 03 2017 09 03 Suicide: An Un-resolved and Under-recognized Health Problem among People of Ilam Province (The Most Popular Suicide Spot in Iran) https://ijph.tums.ac.ir/index.php/ijph/article/view/11011 https://ijph.tums.ac.ir/index.php/ijph/article/download/11011/5697

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 9 2017 09 03 1231 1236 Yan YU Dept. of Cardio-Thoracic Surgery, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, P.R. China Lijuan HU Dept. of Oncology, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, P.R. China Xingu CHEN Dept. of Cardio-Thoracic Surgery, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, P.R. China Mei GE Dept. of Hepatobiliary Surgery, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, P.R. China Huijuan ZHU Dept. of General Surgery, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, P.R. China Yushengstitute of Medical Information, Chinese Academy of Medical Sciences, Beijing, China Yan WANG Institute of Medical Information, Chinese Academy of Medical Sciences, Beijing, China Dongping GAO Institute of Medical Information, Chinese Academy of Medical Sciences, Beijing, China 2017 11 29 2017 11 29   Background: Compared to the rigid image registration task, the non-rigid image registration task faces much more challenges due to its high degree of freedom and inherent requirement of smoothness in the deformation field. The purpose was to propose an efficient coarse-to-fine non-rigid medical image registration algorithm based on a multi-level deformable model. Methods: In this paper, a robust and efficient coarse-to-fine non-rigid medical image registration algorithm is proposed. It contains three level deformation models, i.e., the global homography model, the local mesh-level homography model, and the local B-spline FFD (Free-Form Deformation) model. The coarse registration is achieved by the first two level models. In the global homography model, a robust algorithm for simultaneous outliers (error matched feature points) removal and model estimation is applied. In the local mesh-level homography model, a new similarity measure is proposed to improve the robustness and accuracy of local mesh based registration. In the fine registration, a local B-spline FFD model with normalized mutual information gradient is employed. Results: We verified the effectiveness of each stage of the proposed registration algorithm with many non-rigid transformation image pairs, and quantitatively compared our proposed registration algorithm with the HBFFD method which is based on the control points of multi-resolution. The experimental results show that our algorithm is more accurate than the hierarchical local B-spline FFD method. Conclusion: Our algorithm can achieve high precision registration by coarse-to-fine process based on multi-level deformable model, which ourperforms the state-of-the-art methods.   https://ijph.tums.ac.ir/index.php/ijph/article/view/11765 https://ijph.tums.ac.ir/index.php/ijph/article/download/11765/5848

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 12 2017 11 29 1750 1751 Mahin GHAFARI Dept. of Public Health, School of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran Mahdi MOHAMMADIAN Dept. of Health and Social Medicine, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran Ali Asghar VALIPOUR Dept. of Public Health, School of Public Health, Abadan School of Medical Sciences, Abadan, Iran Abdollah MOHAMMADIAN-HAFSHEJANI Dept. of Epidemiology and Biostatistics, Isfahan University of Medical Sciences, Isfahan, Iran AND Dept. of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2017 11 29 2017 11 29 The Future Prospects of Testis Cancer in the World https://ijph.tums.ac.ir/index.php/ijph/article/view/11780 https://ijph.tums.ac.ir/index.php/ijph/article/download/11780/5861

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 12 2017 11 29 1690 1696 Ahmad TAVAKOLI Dept. of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Farhad REZAEI Dept. of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Gazal Sadat FATEMI NASAB Dept. of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Fatemeh ADJAMINEZHAD-FARD Dept. of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Zahra NOROOZBABAEI Dept. of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Talat MOKHTARI-AZAD Dept. of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2017 11 29 2017 11 29 Background: The most common serological assay to measure anti-influenza antibodies is hemagglutination inhibition (HI) assay. Recently, neutralizing antibodies against influenza virus infection or vaccination can also be detected using microneutralization assays and occasionally, have greater sensitivity than the standard HI assays. The study aimed to compare the sensitivity and specificity of ELISA-based microneutralization (microNT-ELISA) and conventional HI assays in order to detect influenza H1N1 virus antibodies. Methods: MicroNT-ELISA was set up according to the WHO Manual on Influenza Diagnosis and Surveillance in Virology Department of Tehran University of Medical Sciences for the detection of neutralizing antibodies against H1N1 influenza virus in 2013. Fifty serum samples were analyzed with both HI and microNT-ELISA assays. Correlation between methods was calculated by linear regression analysis. Results: The linear correlation coefficient squares, R2, of microNT-ELISA and HI test was 0.61 (P<0.0001) and we observed a high index of coincidence between the two tests. According to McNemar's test, there was no statistically significant difference between these two assays (P>0.05). Conclusion: The sensitivity and specificity of microNT-ELISA assay were high (87% and 73%, respectively) and closely related to gold standard test results. Therefore, microNT-ELISA is recommended as an alternative or complementary test to conventional HI assay for serological and epidemiological purposes.   https://ijph.tums.ac.ir/index.php/ijph/article/view/11767 https://ijph.tums.ac.ir/index.php/ijph/article/download/11767/5849

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 12 2017 11 29 1752 1753 Erfan AYUBI Dept. of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran AND Dept. of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Ali HOSSEINI Dept. of Geography and Urban Planning, University of Tehran, Tehran, Iran Kamyar MANSORI Social Determinants of Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran Salman KHAZAEI Dept. of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran 2017 11 29 2017 11 29 Province Disparity on Female Breast Cancer in Iran https://ijph.tums.ac.ir/index.php/ijph/article/view/11781 https://ijph.tums.ac.ir/index.php/ijph/article/download/11781/5862

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 12 2017 11 29 1697 1703 Masoomeh GHADERIPOUR Dept. of Medical Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Khadijeh KHANALIHA Dept. of Medical Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mehdi MOHEBALI Dept. of Medical Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Center for Research of Endemic Parasites of Iran (CREPI), Tehran University of Medical Sciences, Tehran, Iran Saeedeh SHOJAEE Dept. of Medical Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Maryam BARKHORI Dept. of Medical Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Hamed MIRJALALI Dept. of Medical Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mostafa REZAEIAN Dept. of Medical Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Center for Research of Endemic Parasites of Iran (CREPI), Tehran University of Medical Sciences, Tehran, Iran 2017 11 29 2017 11 29 Background: Microsporidia have been reported as the cause of opportunistic infections in immunocompromised patients in Iran and other countries. There is no data on prevalence of intestinal microsporidia in healthy population of Iran. This study aimed to provide preliminary data on the present status of microsporidia infection in the local healthy population in Jiroft, Kerman Province from southeastern Iran in 2013-2014. Methods: Fresh stool samples were randomly collected from 418 residents in rural 209 (50%) and urban 209 (50%) areas of Jiroft. All of the collected samples were concentrated with conventional formalin-ether, stained with Ryan blue. Microscopic examination was performed with high magnification on each sample separately for the demonstration of microsporidia spores. Results: Microsporidial spores were identified in 41 out of 418 (9.8%) samples including 16.41(39%) from rural areas and 25.41(61%) from urban areas. In general, there was no significant difference between sex, age, job, education, and contact with soil and livestock, water supply, gastrointestinal disorders and microsporidia infection among general population in Jiroft. Conclusion: Intestinal microsporidia infection without clinical manifestations is prevalent in general population resident in southeastern Iran. Appropriate molecular methods are needed for microsporidia species identification.   https://ijph.tums.ac.ir/index.php/ijph/article/view/11768 https://ijph.tums.ac.ir/index.php/ijph/article/download/11768/5850

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 12 2017 11 29 1704 1711 Imen CHATTI Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached Hospital, Sousse, Tunisia Jean-Baptiste WOILLARD U850 INSERM, University of Limoges, CHU Limoges, FHU SUPORT, Limoges, France Amira MILI Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached Hospital, Sousse, Tunisia Isabelle CREVEAUX Laboratoire de Biochimie Médicale, Faculté de Médecine, Clermont-Ferrand, France Ilhem BEN CHARFEDDINE Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached Hospital, Sousse, Tunisia Jihène FEKI Service d’ Oncologie Médicale et Service de Chirurgie Générale, CHU Habib Bourguiba, Université de Sfax, Sfax, Tunisia Sarah LANGLAIS Laboratoire de Biochimie Médicale, Faculté de Médecine, Clermont-Ferrand, France Leila BEN FATMA Dept. of Medical Oncology, CHU Farhat Hached, Sousse, Tunisia Ali SAAD Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached Hospital, Sousse, Tunisia Moez GRIBAA Laboratory of Human Cytogenetics, Molecular Genetics and Reproductive Biology, Farhat Hached Hospital, Sousse, Tunisia Frédéric LIBERT Laboratoire de Pharmacologie et Toxicologie, CHU G. Montpied, Clermont-Ferrand, France Inserm, U1107 NEURO-DOL, Clermont Université, 63001 Clermont-Ferrand, France 2017 11 29 2017 11 29 Background: Pain and its opioid treatments are complex measurable traits. Responses to morphine in terms of pain control is likely to be determined by many factors, including the underlying pain sensitivity of the patient, along with nature and extent of the painful process, concomitant medications, genetic and other clinical and environmental factors. This study investigated genetic polymorphisms implicated in the inter-individual pain response variability to opioid treatment in the Tunisian population. Methods: This prospective association study investigated seven variations in the OPRM1, OPRK1 and COMT gene, which encode Mu and KAPPA opioid receptors, and Catechol-O-methyltransferase enzyme respectively, in a cohort of 129 Tunisian cancer pain patients under oral morphine treatment. Genotyping was performed by simple probe probes on Light Cyler for rs17174629, rs1799972, rs1799971, rs1051659, rs1051660 and rs4680 and by PCR assay for the indel in the promoter region of OPRK1 (rs35566036). A statistical associations study between dose (continuous), dose escalation (yes/no) and SNP or haplotypes were investigated using linear multiple regressions and logistic regressions respectively adjusted on metastases and pain covariates in the R software. Results: We detected significant association of the rs1051660 adjusted on metastasis and pain (P=0.02), no other association has been detected between the 7 polymorphisms screened and the dose of morphine needed for pain relief. Conclusion: This can be explained by the strong genetic heterogeneity in the cosmopolitan areas where our patients were recruited for this study, compared to more homegenous population recruited in other studies.     https://ijph.tums.ac.ir/index.php/ijph/article/view/11769 https://ijph.tums.ac.ir/index.php/ijph/article/download/11769/5851

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 46 12 2017 11 29 1712 1719 Ali ROSTAMI Dept. of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Hooshang KHAZAN Dept. of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Bahram KAZEMI Dept. of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran AND Dept. of Biotechnology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Eshrat Beigom KIA Dept. of Medical Parasitology & Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mojgan BANDEPOUR Dept. of Biotechnology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Niloofar TAGHIPOUR Dept. of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Gholamreza MOWLAVI Dept. of Medical Parasitology & Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2017 11 29 2017 11 29 Background: Trichinellosis is an important and neglected foodborne zoonotic infectious disease in worldwide. The most human outbreaks in recent years have been related to consumption of wild boar meat. This cross-sectional study determined the prevalence of Trichinella spp. infections in hunted wild boars in northern Iran. Methods: Thirty-five hunted wild boars were subjected in this study in 2015. All samples were examined by conventional artificial digestion method to detect of muscle larvae. Genomic DNA was extracted by phenol-chloroform method from isolated larvae. To identify the Trichinella species, a PCR-based method was applied using the internal transcribed spacer 2 (ITS2) and mitochondrial small-subunit ribosomal RNA (rRNA) gene sequences. Results: The overall prevalence of Trichinella spp. infection was 5.7% (2/35, 95%CI= 0-13.4). The mean larval burdens in two positive samples were 0.05 and 6 larvae per gr tissue muscle, respectively. The PCR reaction, using specific primers, yiel