Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 289 296 Pedro GIRON Dept. of Estadística e Investigación Operativa III, Facultad de Estudios Estadísticos, Universidad Complutense de Madrid, Madrid, Spain 2016 03 15 2016 03 15 Background: To analyse time trends in self-rated health in older people by gender and age and examine disability in the time trends of self-rated health. Methods: The data used come from the Spanish National Health Surveys conducted in 2001, 2003, 2006 and 2011-12. Samples of adults aged 16 yr and older were selected. Multivariate logistic regression was used to assess the association between age, gender, socio-economic status, marital status, disability and self-rated health across period study. Results: Women exhibited lower (higher) prevalence of good self-rated health (disability) compared to men. The multivariate analysis for time trends found that good self-rated health increased from 2001 to 2012. Overall, variables associated with a lower likelihood of good self-rated health were: being married or living with a partner, lower educational level, and disability. Conclusion: Trends of good self-rated health differ by gender according to socio-demographic factors and the prevalence of disability.   https://ijph.tums.ac.ir/index.php/ijph/article/view/6260 https://ijph.tums.ac.ir/index.php/ijph/article/download/6260/5321

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 278 288 Javad MOGHRI Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mohammad ARAB Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Arash RASHIDIAN Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Ali AKBARI SARI Dept. of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2016 03 15 2016 03 15 Background: Physician dual practice is a common phenomenon in almost all countries throughout the world, which could potential impacts on access, equity and quality of services. This paper aims to review studies in physician dual practice and categorize them in order to their main objectives and purposes. Methods: Comprehensive literature searches were undertaken in order to obtain main papers and documents in the field of physician dual practice. Systematic searches in Medline and Embase from 1960 to 2013, and general searches in some popular search engines were carried out in this way. After that, descriptive mapping review methods were utilized to categorize eligible studies in this area. Results: The searches obtained 404 titles, of which 81 full texts were assessed. Finally, 24 studies were eligible for inclusion in our review. These studies were categorized into four groups - "motivation and forces behind dual practice", "consequences of dual practice", "dual practice Policies and their impacts", and "other studies" - based on their main objectives. Our findings showed a dearth of scientifically reliable literature in some areas of dual practice, like the prevalence of the phenomenon, the real consequences of it, and the impacts of the implemented policy measures. Conclusion: Rigorous empirical and evaluative studies should be designed to detect the real consequences of DP and assess the effects of interventions and regulations, which governments have implemented in this field.     https://ijph.tums.ac.ir/index.php/ijph/article/view/6259 https://ijph.tums.ac.ir/index.php/ijph/article/download/6259/5320

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 370 375 Shokouh Azam SARRAFZADEH Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran Maryam MAHLOOJIRAD Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran Maryam NOURIZA­DEH Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran Jean-Laurent CASANOVA Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale, INSERM-U1163, Paris, France AND Howard Hughes Medical Institute, NY, USA AND Paris Descartes University, Imagine Institute, Paris, France AND Center for the Study of Primary Immunodeficiencies, Necker Hospital for Sick Children, AP-HP, Paris, France AND St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller branch, the Rockefeller University, New York, NY, USAPediatric Hematology-Immunology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France Zahra POURPAK Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran Jacinta BUSTAMANTE Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale, INSERM-U1163, Paris, France AND Paris Descartes University, Imagine Institute, Paris, France AND Center for the Study of Primary Immunodeficiencies, Necker Hospital for Sick Children, AP-HP, Paris, France AND St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller branch, the Rockefeller University, New York, NY, USA Mostafa MOIN Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran 2016 03 15 2016 03 15   Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare inheritance syndrome, characterized by a disseminated infection with mycobacterium in children following BCG vaccination at birth. Regarding the vaccination program in Iran, it may consider as a public health problem. The pathogenesis of MSMD is dependent on either insufficient production of IFN-gamma (γ) or inadequate response to it. Here, we want to introduce three cases including two siblings and one girl from two unrelated families with severe mycobacterial infections referred to Immunology, Asthma and Allergy Research Institute (IAARI), from 2013 to 2015; their MSMD was confirmed by both cytokine assessment and genetic analysis. Regarding the clinical features of the patients, cell proliferation against a mitogen and BCG antigen was ordered in a lymphocyte transformation test (LTT) setting. ELISA was performed for the measurement of IL-12p70 and IFN- γ in whole blood samples activated by BCG + recombinant human IFN-γ and BCG + recombinant human IL-12, respectively. In contrast to mitogen, the antigen-dependent proliferation activity of the patients’ leukocytes was significantly lower than that in normal range. We identified a homozygous mutation in IL12RB1 gene for two kindred who had a homozygous mutation affecting an essential splice site. For the third patient, a novel frameshift deletion in IL12RB1 gene was found. The genetic study results confirmed the impaired function of stimulated lymphocytes to release IFN-γ following stimulation with BCG+IL-12 while the response to rhIFN-γ for IL-12p70 production was relatively intact. Our findings show that cellular and molecular assessments are needed for precise identification of immunodeficiency disorders especially those without clear-cut diagnostic criteria.     https://ijph.tums.ac.ir/index.php/ijph/article/view/6270 https://ijph.tums.ac.ir/index.php/ijph/article/download/6270/5333

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 387 389 Seongeon KIM Dept. of Physical Education, Sejong University, Seoul, Korea Jooyoung KIM Health and Rehabilitation Major, Kookmin University, Seoul, Korea Yongsoo LEE Dept. of Physical Education, Sejong University, Seoul, Korea Min Keun SEO Division of Sport Science, Konkuk University, Choong Ju, Korea Dong Jun SUNG Division of Sport Science, Konkuk University, Choong Ju, Korea 2016 03 15 2016 03 15 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/6273 https://ijph.tums.ac.ir/index.php/ijph/article/download/6273/5336

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 297 304 Yongqing GAO School of Food Sciences, Guangdong Pharmaceutical University, Zhongshan, China Chunsheng CAI School of Food Sciences, Guangdong Pharmaceutical University, Zhongshan, China Jian LI School of Public Health and Tropical Medicine, Tulane University, New Orleans, USA Wenjie SUN School of Food Sciences, Guangdong Pharmaceutical University, Zhongshan, China AND School of Public Health and Tropical Medicine, Tulane University, New Orleans, USA 2016 03 15 2016 03 15 Background: To examine the effect of nutritional education on children’s breakfast patterns Methods: A kindergarten based nutrition intervention was started in September 2001 among 8 kindergartens in Hefei with a total of 2,012 children aged 4-6 years and their parent pairs. Results: Monthly nutrition education sessions were held over two semesters in kindergartens part of the intervention arm.  The approach in education and the content of other activities were uniform across all the kindergartens. A validated questionnaire was used to record breakfast behavior over 7 days including at least one weekend. The parents recorded the children’s breakfast pattern (frequency, time, and food selection) at baseline, middle, and end of the study. After intervention, there were significant differences at the final stage, but none at the baseline before intervention. There were changes not only in breakfast frequency, but also in the breakfast selection Conclusion: The breakfast pattern of Chinese children can be modified through nutrition education after a long term intervention.   https://ijph.tums.ac.ir/index.php/ijph/article/view/6261 https://ijph.tums.ac.ir/index.php/ijph/article/download/6261/5322

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 376 380 Mohammad Yahya VAHIDI MEHRJARDI Medical Genetics Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AND Dept. of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Masoud DEHGHAN TEZERJANI Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mahmoud NORI-SHADKAM Dept. of Pediatrics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Seyed Mehdi KALANTAR Dept. of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AND Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mohammadreza DEHGHANI Medical Genetics Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AND Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 2016 03 15 2016 03 15 The interpretation of supernumerary chromosome is important for genetic counseling and prognosis. Here, we used SNP array and conventional karyotyping method to identify a denovo marker chromosome originated from chromosome 22 and 11 in a newborn transferred to the Neonatal Intensive Care Unit of Shahid Sadoughi Hospital in 2015.  Clinical abnormalities identified in the newborn were dysmorphic face, intrauterine growth retardation, atrial septal defect (ASD), the hypoplasia of corpus callosum and septum pellucidum. These clinical abnormalities can be related to this marker, and it may help genetic counselor for predicting abnormality risk in susceptible individuals as well as prenatal diagnosis.    https://ijph.tums.ac.ir/index.php/ijph/article/view/6271 https://ijph.tums.ac.ir/index.php/ijph/article/download/6271/5334

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 390 391 Peng QUAN Guangdong Medical University, Dongguan, China Dan HUANG Guangdong Women’s Polytechnic College, Guangzhou, China Yulan YU Guangdong Medical University, Dongguan, China Ruiming LIU Guangdong Medical University, Dongguan, China 2016 03 15 2016 03 15 No Abstract. https://ijph.tums.ac.ir/index.php/ijph/article/view/6274 https://ijph.tums.ac.ir/index.php/ijph/article/download/6274/4652 https://ijph.tums.ac.ir/index.php/ijph/article/download/6274/5337

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 305 313 Dursun TATAR 1. Dept. of Pulmonary Diseases, Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir, Turkey Gunes SENOL Dept. of Infectious Diseases and Clinical Microbiology, Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir Turkey Serpil ALPTEKIN Dept. of Pulmonary Diseases, Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir, Turkey Ebru GUNES Dept. of Pulmonary Diseases, Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir, Turkey Mert AYDIN Dept. of Pulmonary Diseases, Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir, Turkey Ozdal GUNES Dept. of Pulmonary Diseases, Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital, Izmir, Turkey 2016 03 15 2016 03 15 Background: Tuberculosis (TB) is one of the main health issues in Turkey. Extrapulmonary TB cases have significant proportion comparing pulmonary TB cases. The aim of the study was to evaluate the extrapulmonary tuberculosis (EPTB) cases in two regions of Turkey, which have different demographic and socioeconomic characteristics. Methods: In this retrospective cohort study, EPTB cases between 2000 and 2005 in Van and Izmir Provinces of Turkey were analyzed and compared for symptoms, age groups, vaccination status, diagnostic procedures and social-economical conditions within two provinces. Descriptive analytic methods were used. Results: Total of 397 EPTB cases were reviewed retrospectively in Izmir and Van provinces. Pleural TB was most often seen EPTB form (47.6% vs. 32.6%) and female/male ratio was similar in both groups. Patients were in older ages in Izmir Province. Chest pain (20% vs. 32%), cough (33% vs. 26%) and night sweatiness (29% vs. 36%) were leading complaints. Low BCG vaccination rate and higher childhood EPTB were found in Van group, in contrary elderly EPTB was more often in of Izmir group. Conclusion: Frequency of severe forms of EPTB is more often in younger ages in lower social economical condition areas.   https://ijph.tums.ac.ir/index.php/ijph/article/view/6262 https://ijph.tums.ac.ir/index.php/ijph/article/download/6262/5323

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 381 386 Anca PORUMB Dept. of Dentistry, Faculty of Medicine and Pharmacy, University of Oradea, Romania Ioana IGNAT ROMANUL Dept. of Dentistry, Faculty of Medicine and Pharmacy, University of Oradea, Romania Camelia DALAI Dept. of Dentistry, Faculty of Medicine and Pharmacy, University of Oradea, Romania Gabiela CIAVOI Dept. of Dentistry, Faculty of Medicine and Pharmacy, University of Oradea, Romania Ioan Andrei TIG Dept. of Dentistry, Faculty of Medicine and Pharmacy, University of Oradea, Romania 2016 03 15 2016 03 15 This case of a female patient, 14 yr old with association of the two anomalies, which we came across with in 2014, is rarely met in the specialty practice. The impacted canines are part of the group of dental anomalies of position, while the agenesis is part of the group of dental number anomalies. The orthodontic treatment in the two arches has to be differentiated, the therapeutic objectives being, also different in the two arches.     https://ijph.tums.ac.ir/index.php/ijph/article/view/6272 https://ijph.tums.ac.ir/index.php/ijph/article/download/6272/5335

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 392 393 Kaan SAVASOGLU Dept. of Medical Genetics, İzmir Katip Çelebi University, Atatürk Education and Research Hospital, İzmir, Turkey Mehmet EMIN ERDAL Dept. of Medical Biology, Mersin University School of Medicine, Mersin, Turkey 2016 03 15 2016 03 15 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/6275 https://ijph.tums.ac.ir/index.php/ijph/article/download/6275/4653 https://ijph.tums.ac.ir/index.php/ijph/article/download/6275/5338

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 314 321 Wenxin XU Institute of Physical Education and Sport Science, Fujian Normal University, Fuzhou, Fujian, 350007, China Menglong LI Physical Education Institute, Hunan First Normal University, Changsha, Hunan, 410205, China Jiwei YAO Physical Education Institute, Hunan University of Science and Technology, Xiangtan, Hunan, 411201, China 2016 03 15 2016 03 15 Background: Anxiety, depression, and other adverse psychological reactions are often observed in elderly hypertensive patients. Appropriate exercise is a safe form of adjuvant therapy without causing side effects among these patients, with consistent effects on patients’ mental health. In this study, a collective exercise intervention experiment was conducted to evaluate the mental health of elderly hypertensive patients and to verify the effect of the psychological intervention of collective exercise. Method: A total of 115 elderly hypertensive patients aged 60–70 years old were selected as study subjects from May 2012 to January 2015 in Fuzhou City, Fujian Province, China. A total of 57 patients were included in the control group and 58 patients were assigned in the experimental group. Patients in the experimental group participated in a 12 weeks exercise intervention, while patients in the control group didn’t participate in any regular physical exercise. Results: After intervention, the Symptom Checklist-90 (SCL-90), total score, somatization, obsessive-compulsive symptom, interpersonal sensitivity, depression, anxiety, hostility, and paranoia scores of the experimental group were significantly lower than those of the control group (P < 0.05). The positive coping style score of the experimental group was significantly higher than that of the control group (P<0.05); by contrast, the negative coping style score of the experimental group was significantly lower than that of the control group (P < 0.05). Conclusion: The mental health level and coping ability of elderly hypertensive patients can be effectively improved with the proposed treatment.     https://ijph.tums.ac.ir/index.php/ijph/article/view/6263 https://ijph.tums.ac.ir/index.php/ijph/article/download/6263/5324

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 394 395 Faizan SHERAZ Army Medical College, Islamabad, Pakistan Fatima HEMANI Sindh Medical College, Dow University of Health Sciences, Karachi, Pakistan Hasnain Abbas DHARAMSHI Masoomeen Hospital Trust, Karachi, Pakistan 2016 03 15 2016 03 15 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/6276 https://ijph.tums.ac.ir/index.php/ijph/article/download/6276/5340

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 322 328 Ensieh LOTFALI Dept. of Medical Mycology and Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Parivash KORDBACHEH Dept. of Medical Mycology and Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Hossein MIRHENDI Dept. of Medical Mycology and Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Farideh ZAINI Dept. of Medical Mycology and Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Ali GHAJARI Dept. of Medical Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Rasoul MOHAMMADI Dept. of Medical, Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Fatemeh NOORBAKHSH Dept. of Biology, Faculty of Science, Islamic Azad University, Varamin-Pishva, Iran Maryam MO­AZENI Invasive Fungi Research Center, Dept. of Medical Mycology and Parasitology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Aliakbar FALLAHI Dept. of Microbiology & Parasitology & Immunology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Sassan REZAIE Dept. of Medical Mycology and Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2016 03 15 2016 03 15 Background: Candida parapsilosis is an emergent agent of invasive fungal infections. This yeast is one of the five most widespread yeasts concerned in invasive candidiasis. C. parapsilosis stands out as the second most common yeast species isolated from patients with bloodstream infections especially in neonates with catheter. Recently several reports suggested that its reduced susceptibility to azoles and polyene might become a cause for clinical concern, although C. parapsilosis is not believed to be intensely prone to the development of antifungal resistance. Methods: In the present report, One hundred and twenty clinical isolates of C. parapsilosis complex were identified and differentiated by using PCR-RFLP analysis. The isolates were then analyzed to determine their susceptibility profile to fluconazole (FLU), itraconazole (ITC) and amphotericin B. The minimum inhibitory concentration (MIC) results were analyzed according to the standard CLSI guide. Results: All of isolates were identified as C. parapsilosis. No C. metapsilosis and C. orthopsilosis strains were found. Evaluation of the antifungal susceptibility profile showed that only three (2.5%) C. parapsilosis were resistant to fluconazole, three (2.5%) C. parapsilosis were resistant to itraconazole and two (1.7%) C. parapsilosis were amphotericin B resistant. Conclusion: Profiles in clinical isolates of C. parapsilosis can provide important information for the control of antifungal resistance as well as distribution and susceptibility profiles in populations.   https://ijph.tums.ac.ir/index.php/ijph/article/view/6264 https://ijph.tums.ac.ir/index.php/ijph/article/download/6264/5325

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 396 398 Ozgur Zeliha KARAAHMET Dept. of Physical Medicine and Rehabilitation, Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey Ajda BAL Dept. of Physical Medicine and Rehabilitation, Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey Deniz DULGEROGLU Dept. of Physical Medicine and Rehabilitation, Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey Eda GURCAY Dept. of Physical Medicine and Rehabilitation, Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey Halise Hande GEZER Dept. of Physical Medicine and Rehabilitation, Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey Aytul CAKCI Dept. of Physical Medicine and Rehabilitation, Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey 2016 03 15 2016 03 15 No Abstract. https://ijph.tums.ac.ir/index.php/ijph/article/view/6277 https://ijph.tums.ac.ir/index.php/ijph/article/download/6277/5341

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 329 339 Hoorieh SAGHAFI Dept. of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran Majid HAGHJOO Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, Iran Sima SABBAGH Dept. of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran Niloofar SAMIEE Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, Iran Farve VAKILIAN Preventive Cardiovascular Care Research Center, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran Mohammad TAGHI SALEHI OMRAN Roohani Hospital, Babol University of Medical Sciences, Bobol, Iran Masoomeh DADASHI Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, Iran Ahmad AMIN Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, Iran Mohammad KERAMATIPOUR Dept. of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran 2016 03 15 2016 03 15 Background: Familial hypertrophic cardiomyopathy (HCM) is caused by mutations in genes encoding cardiac sarcomere proteins. Nowadays genetic testing of HCM plays an important role in clinical practice by contributing to the diagnosis, prognosis, and screening of high-risk individuals. The aim of this study was developing a reliable testing strategy for HCM based on linkage analysis and appropriate for Iranian population. Methods: Six panels of four microsatellite markers surrounding MYH7, MYBPC3, TNNT2, TNNI3, TPM1, and MYL2 genes (24 markers in total) were selected for multiplex PCR and fragment length analysis. Characteristics of markers and informativeness of the panels were evaluated in 50 unrelated Iranians. Tn National University, Incheon, Republic of Korea 3. Sports Functional Disability Institute, Incheon National University, Incheon, Republic of Korea 2025 04 02 2025 05 09 No Abstract. Not Abstract. https://ijph.tums.ac.ir/index.php/ijph/article/view/38690 https://ijph.tums.ac.ir/index.php/ijph/article/download/38690/8588

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 54 6 2025 06 02 1263 1271 EN Li Zheng 1. College of Integrated Chinese and Western Medicine, Hebei Medical University, Hebei, People’s Republic of China 2. Department of Pharmacy, Xingtai Medical College, Hebei, People’s Republic of China Yiheng Ding Hebei Key Lab of Laboratory Animal Science, Hebei Medical University, Hebei, People’s Republic of China Xinhao Li College of Integrated Chinese and Western Medicine, Hebei Medical University, Hebei, People’s Republic of China Jingxuan Jia College of Integrated Chinese and Western Medicine, Hebei Medical University, Hebei, People’s Republic of China Yanning Li College of Integrated Chinese and Western Medicine, Hebei Medical University, Hebei, People’s Republic of China 2. Hebei Key Lab of Laboratory Animal Science, Hebei Medical University, Hebei, People’s Republic of China Jinsheng Qi College of Integrated Chinese and Western Medicine, Hebei Medical University, Hebei, People’s Republic of China 2024 03 16 2025 06 02 Background: We aimed to investigate whether 20(S)-ginsenoside Rg3 (Rg3) reduced heterogeneity by inducing the maturation of HepG2 cells via the AMP-activated protein kinase (AMPK)/hepatocyte nuclear factor 4A (HNF4A) pathway. Methods: This in vitro cell research study was conducted under the guidance of Hebei Medical University, Hebei, China, from Sep 2022 to Dec 2023. HepG2 cells were treated with varying concentrations of Rg3 in a low glucose microenvironment. The mRNA expression of ALBUMIN (ALB, a marker for hepatocyte function) and HNF4A (a marker for differentiation of HCC cell), and AMPK protein levels were measured after significant changes in cell morphology were observed. Additionally, 5-Aminoimidazole-4-carboxamide1-β-D-ribofuranoside (AICAR) (an AMPK agonist) and Compound C (an AMPK inhibitor) were used to explore further the underlying mechanism. Results: Under treatment of 5 μM, 10 μM, and 20 μM Rg3, some cells became flattened and larger, and there was an increase in the mRNA expression of ALB and HNF4A (P<0.05). However, there was a decreasing trend in AMPK protein content with 8 μM Rg3 (P<0.05). Compared to the control group, some cells exposed to 8 μM Rg3 exhibited pronounced morphological changes, along with upregulated expression of ALB and HNF4A mRNA. However, no such changes were observed when 8 μM Rg3 was combined with 1.6 mM AICAR. Compared to the control group, 10 μM Compound C or 8 μM Rg3 treatments led to similar changes in cell morphology and showed an increasing trend in HNF4A mRNA expression. Additionally, after treatment with Compound C, pHNF4A was mainly in the nucleus, while after Rg3 treatment, it was mostly in the cytoplasm. Conclusion: Rg3 partially induced the maturation of HepG2 cells through the AMPK/HNF4A pathway.     Keywords: 20(S)-ginsenoside Rg3; HepG2; Maturation, Genetics https://ijph.tums.ac.ir/index.php/ijph/article/view/34913 https://ijph.tums.ac.ir/index.php/ijph/article/download/34913/8578

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 54 6 2025 06 02 1171 1178 Haiyan Cai Department of Nursing, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, 310009, China Liwen Pan Department of Nursing, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, 310009, China Pei Zhang Department of Nursing, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou City, Zhejiang Province, 310009, China 2024 05 14 2024 12 22 Background: Perioperative care plays an unparalleled role in the management of strabismus. However, there is still a lack of adequate understanding of the perioperative care and guidelines on nursing measures for strabismus surgery. This article provides a comprehensive review of perioperative care for strabismus, focusing on psychological intervention and rehabilitative nursing. Methods: To comprehensively collect research related to perioperative nursing, we employed a systematic literature retrieval strategy. The databases searched included PubMed, EMBASE, Web of Science, CNKI (China National Knowledge Infrastructure), WanFang, and VIP (Weipu). We read, summarized and review the literatures obtained from databases. Results: We summarized the conclusions in the retained literature and elaborated from two aspects: Psychological intervention and Rehabilitation Nursing. Psychological intervention can be carried out from the following aspects: cognitive behavior intervention, psychological and emotional intervention, social support intervention. Perioperative rehabilitation can be carried out from the following aspects: postoperative nausea and vomiting management, prevention of postoperative infection, visual care, preventing recurrent strabismus post-surgery, avoiding diplopia. Conclusion: Comprehensive perioperative care for patients with strabismus can alleviate negative emotions, improve psychological status, reduce the incidence of postoperative complications, and enhance patients' quality of life. However, further research is still needed to establish detailed intervention strategies for comprehensive care. https://ijph.tums.ac.ir/index.php/ijph/article/view/35515 https://ijph.tums.ac.ir/index.php/ijph/article/download/35515/8569

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 54 6 2025 06 02 1272 1281 Seyed Abbas Motevalian Research Center for Addiction and Risky Behaviors (ReCARB), Psychosocial Health Research Institute (PHRI), Iran Uni-versity of Medical Sciences, Tehran, Iran Seyyed Amir Yasin Ahmadi Preventive Medicine and Public Health Research Center, Psychosocial Health Research Institute, Iran University of Medical Sciences, Tehran, Iran Arash Tehrani-Banihashemi Preventive Medicine and Public Health Research Center, Psychosocial Health Research Institute, Iran University of Medical Sciences, Tehran, Iran 2024 08 05 2024 12 15 Background: Considering the high importance of the problem of obesity and its related factors, we aimed to investigate the mediating role of physical activity in the relationship between personality traits and body mass index (BMI) in the participants of the employees’ health cohort study of Iran (EHCSIR) using generalized structural equation modeling (GSEM). Methods: A secondary analysis with cross-sectional approach was conducted on the existing data using multilevel GSEM. The primary data of the cohort was collected from July 2017, Iran University of Medical Sciences, Tehran, Iran. Personality traits were exposure, physical activity was the mediator, and BMI was the outcome. Sex was the stratifying variable. Then, pathways with the largest P values were removed one by one using backward stepwise approach. Results: The data of a total of 3554 participants of EHCSIR were used. Sex was subjected for grouping the analysis. In males, extroversion (EX) was the only personality trait associated with both physical activity and BMI. In the direct pathway, EX was positively associated with BMI. In the indirect pathway, EX was negatively associated with BMI (P <0.1). The total effect was positive. In females, physical activity was not associated with BMI, and therefore, no indirect pathway was formed from personality traits to BMI (P >0.1). Conclusion: The role of personality traits in obesity was more dominant in females, while in males, physical activity had a role in obesity. The hypothesized mediation pathway of the study title was not approved in females, and in males, was approved only for EX personality trait. https://ijph.tums.ac.ir/index.php/ijph/article/view/36272 https://ijph.tums.ac.ir/index.php/ijph/article/download/36272/8579

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 54 6 2025 06 02 1179 1192 Pavan Narapaka Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research (NIPER) Hajipur, Dist. Vaishali, Bihar, India Manisha Singh Department of Medical Oncology, Mahavir Cancer Sansthan and Research Centre, Patna, Bihar, India Sarasa Meenakshi Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research (NIPER) Hajipur, Dist. Vaishali, Bihar, India Jaseena C V Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research (NIPER) Hajipur, Dist. Vaishali, Bihar, India Manasa Goudicharla Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research (NIPER) Hajipur, Dist. Vaishali, Bihar, India Krishna Murti Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research (NIPER) Hajipur, Dist. Vaishali, Bihar, India Sameer Dhingra Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research (NIPER) Hajipur, Dist. Vaishali, Bihar, India 2024 08 28 2024 12 14 Background: This study aimed to provide comprehensive information on translated versions of the 9-item shared decision-making questionnaire, widely used to measure patient involvement in shared decision-making, by combining psychometric validation information. Methods: We searched various databases such as PubMed, Scopus, Google Scholar, along with developer website to gather pertinent literature published until Feb, 2024. This psychometric validation carried out based on item characteristics, content validity, and factor analysis results of individual studies. Our evaluation was based on predetermined cut-off values for item difficulty, discrimination index, Cronbach's alpha, Kaiser Meyer Olkin factor (KMO), Bartlett's test of sphericity, and factor extraction and rotation, confirmatory factor analysis range. The European Social Research Council guidance on the conduct of narrative synthesis in systematic reviews was employed for synthesis of validation results. Results: The final analysis included nine studies with 3090 participants from various countries, and most participants had adequate literacy, and age range was 30-60 yr. Most model versions had a good fit, and all studies reported satisfactory results, except for one study's discrimination index values. The tool's validity was satisfactory. Most of the studies reported a convenient sample was the main limitation, along with recall bias in the final responses. Conclusion: The 9-item shared decision-making tool can be used to measure patient involvement in shared decision-making in validated language-respected countries, as proper evaluation procedures reported satisfactory results in the confirmatory analysis models and reliability testing.   https://ijph.tums.ac.ir/index.php/ijph/article/view/36488 https://ijph.tums.ac.ir/index.php/ijph/article/download/36488/8570

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 54 6 2025 06 02 1282 1290 Marzie Salandari Rabori Occupational Environment Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran Aghdas Souresrafil Department of Health Services and Health Promotion, School of Health, Rafsanjan University of Medical Sciences, Rafsanjan, Iran Mohsen Rezaeian 1. Occupational Environment Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran 2. Department of Epidemiology and Biostatistics, School of Health, Rafsanjan University of Medical Sciences, Rafsanjan, Iran Hasan Ahmadinia 1. Occupational Environment Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran 2. Department of Epidemiology and Biostatistics, School of Health, Rafsanjan University of Medical Sciences, Rafsanjan, Iran Roya Bahrami Department of Psychology, Ali-Ibn Abi-Talib Hospital, Rafsanjan University of Medical Sciences, Rafsanjan, Iran Mahdie Sadat Hosseini Educator of Midwifery Department, School of Nursing Midwifery Health, Islamic Azad University, Kerman, Iran Maryam Hasanshahi Nurse Emergency Department, Ali-Ibn Abi-Talib Hospital,Rafsanjan University of Medical Sciences, Rafsanjan, Iran Azam Bagherizade Clinical Laboratory, Faculty of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran 2024 05 12 2025 06 02 Background: Suicide is an intentional act that results in the death of a person. Clinical researchers show that a new era has begun in understanding suicide pathophysiology. Our study assessed serum minerals (Fe, Mg) and vitamins (D, B12) to see if they are related to suicide attempts. Methods: This is a cross-sectional study conducted in Ali-ebn-Abi Taleb Hospital, Rafsanjan City Central District, Kerman Province, Iran in 2022. Prior to measuring the quantity of essential minerals and vitamins in the blood, the degree of depression was assessed using the Beck depression severity scale. Chi-square, Independent T-test, Kruskal-Wallis, and Mann Whitney U test were performed to ascertain the existence of an association between these substances within the body and suicide attempts. Results: Thirty-two attempted suicides (24 women and 8 men, mean age 14-46 yr) were included in this study. The mean and standard deviation of depression scores for 32 candidates was 16.43 ± 26.74. Moreover, our results show nearly 46.7% (50% women and 37.5% men) of participants suffer from vitamin D deficiency and 6.7% from Mg deficiency, half of them have also severe depression. Conclusion: One of the reasons for the cause of depression and suicide attempt could be the status of minerals and vitamins in the body. Therefore, it is likely that a suitable diet and checking blood factors might help to reduce suicide attempts in a society. https://ijph.tums.ac.ir/index.php/ijph/article/view/35486 https://ijph.tums.ac.ir/index.php/ijph/article/download/35486/8580

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 54 6 2025 06 02 1193 1203 Yan Gao Department of Obstetrical, First Affiliated Hospital, Heilongjiang University of Chines Medicine, Harbin 150001, Heilongjiang Province, China Limin Peng Department of Obstetrical, First Affiliated Hospital, Heilongjiang University of Chines Medicine, Harbin 150001, Hei-longjiang Province, China Chengkun Yuan Department of Obstetrical, First Affiliated Hospital, Heilongjiang University of Chines Medicine, Harbin 150001, Heilongjiang Province, China Shanshan Zhang Department of Obstetrical, Beidahuang Group General Hospital, Harbin 150000, Heilongjiang Province, China 2024 12 14 2025 01 25 Background: This study aimed to evaluate the efficacy and safety of intravenous immunoglobulin (IVIG) therapy for recurrent miscarriage (RMC) using meta-analysis. Methods: Literature from Jan 1990 to Feb 2024 was searched in PubMed, etc., using keywords such as “IVIG”, “repetitive miscarriage”, and “RMC”. Two authors independently assessed the literature quality and risk of via Cochrane handbook, and extracted basic information and outcome indicator data. Meta-analysis was performed employing Review Manager 5.3. Results: Eleven studies were involved, comprising 842 patients, of which 391 received IVIG therapy and 451 received placebo treatment. Relative to placebo group, IVIG group had a notably higher overall live birth rate (OR=2.24, 95% CI=1.68~2.98, Z=5.51, P<0.00001) and a greatly lower miscarriage rate (OR=0.46, 95% CI=0.22~0.95, Z=2.09, P=0.04). Subgroup analysis revealed that both primary and secondary RMC patients in IVIG group had markedly higher live birth rates versus placebo group (OR=2.13, 95% CI=1.18~3.83, Z=2.51, P=0.01; OR=1.50, 95% CI=0.98~2.30, Z=1.96, P=0.04). Nevertheless, the adverse reaction (AR) rate in