Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 41 1 2012 01 15 1 8 S Dhiman Defense Research Laboratory, 784001, Tezpur Assam K Yadav Defense Research Laboratory, 784001, Tezpur Assam D Goswami Defense Research Laboratory, 784001, Tezpur Assam NG Das Defense Research Laboratory, 784001, Tezpur Assam I Baruah Defense Research Laboratory, 784001, Tezpur Assam L Singh Defense Research Laboratory, 784001, Tezpur Assam 2015 10 03 Malaria remains a complex problem during the pregnancy, which threatens > 35 millions pregnant women every year. Malaria pathogenesis in pregnancy results in accumulation of infected RBCs in the intervillous spaces causing severe alterations leading to the reduced materno-foetal exchanges. In this article we have revisited the current evidences of clinical implications and overall burden of malaria in pregnancy. Many adverse aftermaths including, low birth weight, intrauterine growth retardation, preterm delivery, stillbirth and anemia were found associated with malaria in pregnant women. Despite of worldwide comprehensive control programmes for malaria in pregnancy, the disease control has been a daunting task everywhere. Socio cultural, economical, lack of awareness and various logistic problems compound the disease in developing countries. Thorough evidence based information and estimates, education and awareness and strengthening of prevention programmes are needed urgently to achieve success in malaria control in pregnancy. https://ijph.tums.ac.ir/index.php/ijph/article/view/2627 https://ijph.tums.ac.ir/index.php/ijph/article/download/2627/2607

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 41 1 2012 01 15 9 16 HC Wang Dept. of Hematology, Qilu Hospital, Shandong University, Jinan, Shandong, China HL Lin School of Public Health and Primary Care, the Chinese University of Hong Kong, Shatin, NT, Hong Kong N Shao Dept. of Hematology, Qilu Hospital, Shandong University, Jinan, Shandong, China JR Zhang Dept. of Hematology, Qilu Hospital, Shandong University, Jinan, Shandong, China J Zou Dept. of Hematology, Qilu Hospital, Shandong University, Jinan, Shandong, China CY Ji Dept. of Hematology, Qilu Hospital, Shandong University, Jinan, Shandong, China 2015 10 03 Background: A case-control study was carried out to investigate the roles of prior allergies and family history of cancers and their interaction in the etiology of adult leukemia. Methods: Prior allergies status and family history of cancers in first-degree relatives were compared between 131 incident leukemia cases and 206 hospital-based controls. Odds ratios (OR) were estimated using an unconditional regression model taking into account potential confounding factors. Results: Significant association between adult leukemia and prior allergies and family history of cancer (OR=2.09, 95% CI: 1.22-3.58 for prior allergies; and OR=2.35, 95% CI: 1.09-5.03 for family history of cancer, OR=15.88, 95% CI: 1.77-142.55 for both the two factors (+), respectively) was found after adjusting for potential confounding factors. Conclusion: Prior allergies and family history of cancers may be risk factors for adult leukemia; their interaction was likely to be synergistic rather than additive for the risk of leukemia. https://ijph.tums.ac.ir/index.php/ijph/article/view/2628 https://ijph.tums.ac.ir/index.php/ijph/article/download/2628/2608

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 41 1 2012 01 15 17 27 K Nakamura Dept. of Psychiatry, School of Medicine, Jikei University, Tokyo, Japan H Seto Dept. of Psychiatry, School of Medicine, Jikei University, Tokyo, Japan S Okino Dept. of Psychiatry, School of Medicine, Jikei University, Tokyo, Japan K Ono Dept. of Psychiatry, School of Medicine, Jikei University, Tokyo, Japan M Ogasawara Tokyo Dome Corporation, Tokyo, Japan Y Shibamoto Mitsubishi Motors Corporation, Tokyo, Japan T Agata Dept. of Public Health, School of Medicine, Jikei University, Tokyo, Japan K Nakayama Dept. of Psychiatry, School of Medicine, Jikei University, Tokyo, Japan 2015 10 03 Background: Sick leave from work due to psychiatric disorders is a major public health problem, not only in Japan but also worldwide. As males and females in Japan tend to differ in their approach to work, a gender difference in perfectionism might be expected. We investigated the background factors leading to long-term absence from work due to sickness among psychiatric outpatients in Japan.    Methods: We surveyed 73 psychiatric outpatients who were absent from work for a long time (POAWs) and 228 employees without long-term sickness absence as controls. GHQ-30, NEO-FFI, MPS, RSS and questionnaires inquiring about background factors, including relationships with others, was used, and the data were compared between males and females. Results: Male POAWs had a significantly higher tendency for depression and perfectionism than the controls, but in females this difference was not significant. With regard to personal relationships of POAWs, males had worse relationships with superiors and colleagues, whereas females had worse relationships with superiors, colleagues, and family. Conclusions: The data suggested that male workers exhibiting perfectionism tend to undertake too much work and become exhausted when trying to cope with complex human relationships in the workplace. Female workers having the double burden of family commitment and perfectionism tend to be isolated in terms of personal relationships, leading to exhaustion both in and outside the workplace. https://ijph.tums.ac.ir/index.php/ijph/article/view/2629 https://ijph.tums.ac.ir/index.php/ijph/article/download/2629/2609

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 41 1 2012 01 15 28 36 B Aina Mardiah Dept. of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti AS Hazizi Dept. of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti MT Mohd Nasir Dept. of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Y Zaitun Dept. of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti JM Hamid Jan Nutrition Programme, School of Health Sciences, Universiti Sains Malaysia, 16150 Kubang 2015 10 03 Background: This was a cross-sectional study on the gender differences in weight-control behavior. The strategies used, weight status, weight satisfaction, and proportion of individuals attempting to lose weight among 233 government employees (104 men and 129 women) working in the Federal Government Building in Penang, Malaysia, were assessed. Methods: Anthropometric indicators such as body mass index, waist-to-hip ratio, and body fat percentage were measured to determine the subjects' body weight status. A questionnaire covering the following items was used to assess weight-control behavior: social support, self-monitoring, self-efficacy, outcome expectations, planning, preparation/buying, portion control, social interactions, and cognitive behavioral strategies. Results: About 50% of the subjects were classified as overweight. Based on percent body fat percentage, 70% of them were classified as having unhealthy levels of body fat. Women were found to be more dissatisfied with their current weight, and were more likely to attempt weight reduction compared to men. Women reported higher levels of social support for dieting and had better expectations for diet and exercise (P < 0.05). They also reported higher use of weight control strategies. For self-monitoring, although no gender-dependent differences (P > 0.05) were observed, women reported more frequent self-monitoring of diet, whereas men reported more frequent self-monitoring of exercise. Conclusion: Health care professionals and researchers should be aware of the different strategies used by men and women in order to plan and/or implement community-wide weight management programmes. https://ijph.tums.ac.ir/index.php/ijph/article/view/2630 https://ijph.tums.ac.ir/index.php/ijph/article/download/2630/2610

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 41 1 2012 01 15 37 44 Raida S Yahya Children Hospital, Faculty of Medicine, Mansoura University, Mansoura, Egypt Manal I Fouda Dept. of Clinical Pathology, Faculty of Medicine, Mansoura University, Mansoura, Egypt Hatim A El-Baz Dept. of Biochemistry, National Research Center, Cairo, Egypt Tamer E Mosa Dept. of Biochemistry, National Research Center, Cairo, Egypt Mohamed D Abd ElMaksoud Dept. of Biochemistry, National Research Center, Cairo, Egypt 2015 10 03 Background: The aim of this study was to detect the prognostic significance of survivin level and the expression of total p53 in acute lymphoblastic leukemia (ALL) and its correlation to patients' outcome. Methods: Sixty two children newly diagnosed with acute lymphoblastic leukemia were treated with chemotherapy and followed up for 2 years or until death. Twenty apparently healthy volunteers with matched age and sex were taken as control. Survivin protein was measured by quantitative sandwich enzyme immunoassay and total human p53 was measured by Flow cytometry in peripheral blood at diagnosis and at complete remission. Results: A highly significant elevation (P<0.0001) was found in survivin protein and total p53 levels in acute lymphoblastic leukemia children patients at diagnosis compared to controls. At complete remission a significant decrease of the two indices were found in ALL patients compared to those at diagnosis (P<0.0001).  Survivin protein and total p53 was significantly higher in non-survived compared to survived group (P<0.0001 & P=0.016, respectively). A positive correlation was found between survivin level and total human p53 level in children with ALL (r=0.501 & P<0.0001). Conclusion: survivin protein is related to anti-apoptotic proteins and its high expression lead to unsuccessful treatment of ALL. Survivin and TP53 are new prognostic tools in ALL, independent of age and sex. https://ijph.tums.ac.ir/index.php/ijph/article/view/2631 https://ijph.tums.ac.ir/index.php/ijph/article/download/2631/2611

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 41 1 2012 01 15 45 49 Xin Ying International Healthcare Center, the Second Affiliated Hospital, School of Medicine, Zhejiang Univer Yan Jiang Dept. of Clinical Laboratory, the Second Affiliated Hospital, School of Medicine, Zhejiang Universit Yafang Qian International Healthcare Center, the Second Affiliated Hospital, School of Medicine, Zhejiang Univer Zhenyan Jiang International Healthcare Center, the Second Affiliated Hospital, School of Medicine, Zhejiang Univer Zhenya Song International Healthcare Center, the Second Affiliated Hospital, School of Medicine, Zhejiang Univer Changjun Zhao International Healthcare Center, the Second Affiliated Hospital, School of Medicine, Zhejiang Univer 2015 10 03 Background: The aim of this study was to assess the association between insulin resistance, metabolic syndrome and nonalcoholic fatty liver disease (NAFLD) in Chinese adults. Methods: Fifty five subjects with NAFLD and 55 controls were enrolled for the study. Waist circumference, blood pressure, plasma triglyceride, high density lipoprotein cholesterol and fasting plasma glucose concentrations and homeostasis model assessment of insulin resistance (HOMA-IR) values as an index used to quantify insulin resistance were measured and analyzed. Logistic regression was analyzed to predict independent risk factors of NAFLD. Results: The prevalence of metabolic syndrome in NAFLD group was obviously higher than in controls group (47.3% VS 3.6%, P<0.001). There were all significant differences of each component of metabolic syndrome and HOMA-IR values in comparison of nonalcoholic fatty liver disease (NAFLD) and controls group. In a logistic regression analysis, age, diastolic blood pressure, waist circumference and HOMA-IR were the covariates independently associated with the presence of NAFLD (Odds Ratio=1.107, 1.083, 1.218 and 16.836; 95% CI: 1.011～1.211, 1.001~1.173, 1.083～1.370 and 3.626~78.168, respectively; P<0.05) Conclusion: NAFLD was closely associated with metabolic syndrome and insulin resistance was a very strong predictor of NAFLD.  https://ijph.tums.ac.ir/index.php/ijph/article/view/2632 https://ijph.tums.ac.ir/index.php/ijph/article/download/2632/2612

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 41 1 2012 01 15 50 58 T Bahcebasi Dept. of Public Health, Medical Faculty, Duzce University, Düzce-Turkey C Guler Dept. of Public Health, Hacettepe University, Medical Faculty, Ankara-Turkey H Kandis Dept. of Emergency Medicine, Duzce University, Medical Faculty, Düzce- Turkey İ H Kara Dept. of Family Medicine, Duzce University, Medical Faculty, Düzce- Turkey 2015 10 03 Background: In 1999, Duzce suffered two consecutive devastating earthquakes above magnitude 7 in August and November. In the present study, we aimed to evaluate the indoor air quality of coffeehouses by determining carbon monoxide (CO) levels and their contributing factors in coffeehouses built before and after the earthquake. Methods: We conducted our study in 76 Turkish coffeehouses in Duzce in winter (November 2007-March 2008) during rush hours (18:00-23:00). The Turkish coffeehouses included in the study werpeutic methods have been used to return the color of skin in vitiligo. These methods include non-invasive treatment and surgical techniques. Among all these therapies, cell transplantation is an advanced procedure in regenerative medicine. Extraction of melanocytes from normal skin and then their cultivation in the laboratory provides a large number of these cells, the transplanting of which to depigmentation areas stimulates the site to irreversibly produce melanin. Results: The transplantation methods of these cells have been evolved over many years and the methods of producing blister have been changed to the injection of these cells to the target sites. Conclusion: In this review, autologous cultured melanocyte transplantation has been considered to be the most viable, safe, and effective method in the history of vitiligo treatments.   https://ijph.tums.ac.ir/index.php/ijph/article/view/16508 https://ijph.tums.ac.ir/index.php/ijph/article/download/16508/6316

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 3 2019 03 12 554 555 Hua ZHANG Department of Medical Insurance, School of Public Health, Southeast University, Nanjing, Jiangsu, China AND Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China Mingdong HUO Zhongda Hospital Affiliated to Southeast University, Nanjing, Jiangsu, China Yao TONG Department of Medical Insurance, School of Public Health, Southeast University, Nanjing, Jiangsu, China Pei LIU Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China AND Department of Epidemiology and Biostatistics, School of Public Health, Southeast University, Nanjing, Jiangsu, China 2019 03 12 No Abstract### https://ijph.tums.ac.ir/index.php/ijph/article/view/16543 https://ijph.tums.ac.ir/index.php/ijph/article/download/16543/6339

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 3 2019 03 12 444 450 Mingde YANG Department of Anesthesiology, Yidu Central Hospital of Weifang, Qingzhou 262500, P.R. China Yan YU Department of Nursing, Yidu Central Hospital of Weifang, Qingzhou 262500, P.R. China Quanfeng LIU Department of Anesthesiology, Yidu Central Hospital of Weifang, Qingzhou 262500, P.R. China 2019 03 12 Background: We aimed to investigate the analgesic effect and immune function of elderly patients with colon cancer after application of sevoflurane and isoflurane anesthesia. Methods: Overall, 130 patients with colon cancer in Yidu Central Hospital of Weifang  (Weifang, China) from February 2014 to January 2017 were collected and randomly divided into sevoflurane group (SEV group) and isoflurane group (ISO group). The pain score, immune indexes, postoperative cognitive index, extubation time, awakening time and S100R protein were analyzed. Results: The pain scores in SEV group at 5 min, 1 h and 3 h during surgery were significantly lower than those in ISO group (P=0.001, respectively). The levels of IL-6 in both groups of patients were higher at T1 and T2 than those at T0 (P=0.001). The levels of TNF-α in SEV group at T2 and T3 were significantly higher than that at T0 (P=0.001). The levels of CD80 in both groups of patients at T2 and T3 were obviously higher than those at T0 (P=0.001). Moreover, the extubation time, the response time to language and awakening time in SEV group were also remarkably shorter than those in ISO group (P=0.001). After continuous anesthesia in both groups of patients, the degrees of decline in ISO group were significantly higher than those in SEV group (P=0.001). Conclusion: Sevoflurane has a superior anesthetic effect to isoflurane in elderly patients with colon cancer, can reduce the degree of pain, improve the awakening condition and increase the immune function, so it is worthy of clinical application.         https://ijph.tums.ac.ir/index.php/ijph/article/view/16520 https://ijph.tums.ac.ir/index.php/ijph/article/download/16520/6322

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 3 2019 03 12 400 409 Jamaleddin KHEDMATI Department of Pharmacoeconomics and Pharmaceutical Administration, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Majid DAVARI Department of Pharmacoeconomics and Pharmaceutical Administration, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Mohsen AARABI Department of Epidemiology, Mazandaran University of Medical Sciences, Mazandaran, Iran Fatemeh SOLEYMANI Department of Pharmacoeconomics and Pharmaceutical Administration, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Abbas KEBRIAEEZADEH Department of Pharmacoeconomics and Pharmaceutical Administration, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran 2019 03 12 Background: Global experience as well as expert views weight the Family Physician program (FPP) as a primary solution for various problems of healthcare system in Iran. In spite of the valuable information has been collected during conducting FPP, few studies have been done to evaluate the actual performance of this program. This study reviewed the studies related to the evaluation of the FPP systematically. Methods: The authors systematically searched PubMed, Web of Science, Scopus, Embase, Irandoc and SID for articles published in English and Persian until Nov 2017 without limitation for starting time. Selection stages of the articles were done based on PRISMA flow diagram guidelines. Results: Of all articles evaluated, 19 were selected. Four articles were removed due to inadequate quality of the study. Only one article evaluates urban and the rest are about rural. Eight articles were categorized as the process evaluations and 12 outcome assessments (one of them was common). Conclusion: We achieved three main findings. First, the rural FPP has improved access to the healthcare services, but improvement in patient finding and quality of cares remains questionable. Second, there are considerable concerns in the referral system between levels I and II in both urban and rural programs. Third, there was no efficient planning to implement the FP as the gatekeepers of health care system effectively. These issues deprived the efficiency aim of FPP and need serious consideration.   https://ijph.tums.ac.ir/index.php/ijph/article/view/16509 https://ijph.tums.ac.ir/index.php/ijph/article/download/16509/6317

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 3 2019 03 12 559 560 Fatemeh SANIE-JAHROMI Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran Hamideh MAHMOUDINASAB Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran Mostafa SAADAT Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran 2019 03 12 No Abstract### https://ijph.tums.ac.ir/index.php/ijph/article/view/16545 https://ijph.tums.ac.ir/index.php/ijph/article/download/16545/6341

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 3 2019 03 12 451 457 Kusuma SWANGPUN Community Health Development Program, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand Manop KANATO Department of Community Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand Poonrut LEYATIKUL Department of Occupational Health, Faculty of Public Health, Vongchavalitkul University, Nakhon Ratchasima, Thailand 2019 03 12 Background: There have been scientific studies on risk and protective factors associated with child outcomes. However, how risk factors interact to produce outcomes is not clearly understood. We assessed the association between school location, grade, and drug abuse risks among preschoolers. Methods: This cross-sectional study included 3353 participants aged 2-6 yr (mean: 4.6, SD: 1.03) enrolled in childcare centers and kindergarten classes in 2016 in Phuket, Thailand. The risk of drug abuse was measured using questionnaires, completed by teachers and caregivers. Data were analyzed using descriptive statistics, odds ratio with 95% confidence intervals and Chi-square. Results: The prevalence of drug abuse risk factors was as follows: sleep problems=1.28%, aggression=1.10%, attention-deficit hyperactivity disorder (ADHD)=3.61%, learning disabilities (LDs)=4%, family members’ substance abuse=12.53%, parents’ changing marital status=6.53%, conflict between parents/guardians=1.88%, family poverty=3.37%, and easy access to drugs in the community=5.16%. Sleep problems in children were significantly related to family members’ substance abuse, family poverty, and easy access to drugs in the community (PS<.05). LDs were significantly related to parents’ changing marital status, conflict between parents/guardians, family poverty, and easy access to drugs in the community (PS<.05). ADHD was significantly related to family members’ substance abuse, parents’ changing marital status, conflict between parents/guardians, and family poverty (PS<.05). Conclusion: The prevalence of drug abuse risks among preschoolers was 25.86%. Multidisciplinary teams should provide appropriate interventions.   https://ijph.tums.ac.ir/index.php/ijph/article/view/16521 https://ijph.tums.ac.ir/index.php/ijph/article/download/16521/6323

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 3 2019 03 12 410 420 Farzad PAKDEL Department of Oculofacial, Eye Research Center, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran Roghayeh GHAZAVI Vice Chancellery of Research and Technology, Isfahan University of Medical Sciences, Isfahan, Iran Roghayeh HEIDARY International Virtual Ophthalmic Research Center, Tehran, Iran Athena NEZAMABADI Department of Oculofacial, Eye Research Center, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran Maryam PARVIZI Department of Pathology, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Mahsa HAJI SAFAR ALI MEMAR Department of Oculofacial, Eye Research Center, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran Reza GHAREBAGHI International Virtual Ophthalmic Research Center, Tehran, Iran Fatemeh HEIDARY Immunoregulation Research Center, Shahed University, Tehran, Iran AND Department of Ophthalmology, Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran 2019 03 12 Background: Association of Selenium (Se) deficiency, an essential trace element, has been found with human diseases. Identifying literature trends on the effects of Se on the thyroid may guide in planning future studies. Methods: A literature search was conducted using the Web of Science database to identify studies on Se and the thyroid published over the 20 years duration (1995-Dec 2014). Scientometric indices were used to draw field maps. The scientific processes, structure, evidence history, and international collaborations were included in the map. The most influential authors, journals, institutions, and countries were also examined. Results: Our search identified 184 research and review papers. The number of scientific studies on Se and the thyroid has been irregular, but interest in this topic has increased in recent years. The highest number of studies was published in 2014 (16 papers) and overall growth factor of publication was 3.78. Overall, 744 authors from 282 institutions in 43 countries published in this field. The author J. Kohrle (828 citations, 14 publications), and German scientists (1272 citations, 30 publications) were most influential. Conclusion: This study reveals the interrelationships between different publications on the effects of Se on the thyroid. Leading scientific issues and their extent of impact were successfully determined by examining citations. The results of systematic citations and mapping fields can be used to assist in policy and management contexts. https://ijph.tums.ac.ir/index.php/ijph/article/view/16510 https://ijph.tums.ac.ir/index.php/ijph/article/download/16510/6318

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 3 2019 03 12 561 563 Bijan PIRNIA Department of Psychology, Faculty of Humanities, University of Science and Culture, Tehran, Iran AND Behavioral Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Kambiz PIRNIA Bijan Center for Substance Abuse Treatment, Tehran, Iran Khadijeh BAZYARI Department of Psychology, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran Fatemeh ASLANI Department of Psychology, Karaj Branch, Islamic Azad University, Karaj, Iran Parastoo MALEKANMEHR Department of Psychology, Hamedan Branch, Islamic Azad University, Hamedan, Iran 2019 03 12 No Abstract### https://ijph.tums.ac.ir/index.php/ijph/article/view/16546 https://ijph.tums.ac.ir/index.php/ijph/article/download/16546/6342

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 3 2019 03 12 458 464 Fan CHEN Department of Forensic Analytical Toxicology, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, China Yi YE Department of Forensic Analytical Toxicology, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, China Qingtao WEI Department of Forensic Analytical Toxicology, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, China Jianxia CHEN Department of Forensic Analytical Toxicology, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, China Hao WU Department of Forensic Analytical Toxicology, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, China Youyi YAN Department of Forensic Analytical Toxicology, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, China Linchuan LIAO Department of Forensic Analytical Toxicology, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, China 2019 03 12 Background: Carbon monoxide (CO) poisoning is one of the most important intoxications in the modern world. This study aimed to identify the characteristics of CO poisoning deaths in Sichuan province in the west of China. Methods: Data on fatal non-fire-related carbon monoxide poisoning in Sichuan from 2008 to 2016 were obtained from the Department of Forensic Analytical Toxicology of Sichuan University and were analyzed by the month and year of registration of death, sex, age group, manner of death, source of CO, and location of CO exposure. Comparing with the previous studies carried out in Wuhan and Shanghai to identify the regional differences of CO poisoning in China. Results: A total of 165 non-fire related CO poisoning cases including 237 victims were recorded. Over 90% of the victims died from accidental poisoning. Non-fire related CO poisoning occurred more frequently in winter months and was most prevalent in individuals aged between 18 and 60 yr old. Showering gas accident and coal or charcoal burning was found to be the major source of CO in accident and in suicide cases, respectively. Furthermore, significant regional differences of CO poisoning have been detected in the manner of death and the source of CO. Conclusion: These findings will be valuable in the targeted prevention of non-fire related CO poisoning in China.       https://ijph.tums.ac.ir/index.php/ijph/article/view/16522 https://ijph.tums.ac.ir/index.php/ijph/article/download/16522/6324

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 48 3 2019 03 12 564 565