Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 37 2 2008 06 15 1 8 AA Karimi SH Ahmadi S Davoodi M Marzban N Movahedi K Abbasi A Salehi Omran M Shirzad S Sadeghian SH Abbasi M Lotfi-Tokaldany M Soleymanzadeh A Fehri M Sheikh Fathollahi 2015 10 03 Background: The use of cardiac surgical database is necessary for evaluating and improving the quality of care. The aim of this report was to provide useful information for surgeons in Iran and other countries for their daily practice. Methods: We analyzed data from 14288 consecutive patients in four different types of procedures, namely isolated coro­nary artery bypass grafting (CABG), combined CABG and valve (CABG-V), only valve (V), and other adult cardiac surgical op­erations from 2002 to 2006. Results: The activity load increased from 1765 in 2002 to 3309 surgical operations in 2006 with almost 87.2% of activity be­ing isolated CABG. The mortality rate for CABG was 1%, which decreased from 1.7% to 0.9% over the five years. The mor­tality rates for CABG-V and V were 5.8% and 4.8% in the last year of the study, respectively. Over the 5 yr period, the pro­portion of urgent operations increased substantially from 4% to 24.5% (P< 0.0001), causing a reduction in elective op­erations. The mean length of hospital stay for the entire population was 8.38±5.74 d, which remained almost steady dur­ing the study period. Conclusion: This database can serve as a valuable resource of preoperative measurers and surgical outcomes for surgeons and researchers with a view to improving overall surgical performance. https://ijph.tums.ac.ir/index.php/ijph/article/view/2049 https://ijph.tums.ac.ir/index.php/ijph/article/download/2049/2030

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 37 2 2008 06 15 9 14 M Niyyati S Rezaie F Rahimi M Mohebali AH Maghsood SH Farnia M Rezaeian 2015 10 03 Background: Acanthamoeba castellanii is the important cause of amoebic keratitis in Iran. The key molecule in pathogene­sis of Acanthamoeba keratitis is Mannose Binding Protein (MBP) led to adhesion of amoeba to corneal epithelium. Subse­quent to adhesion other cytopathic effects occur. The goal of this study was to identify the molecular characterization of a gene encoding MBP in an Iranian isolate of A.castellanii in order to pave the way for further investigations such as new therapeu­tic advances or immunization. Methods: A.castellanii was cultured on non nutrient agar. Extraction of DNA was performed by phenol-chloroform method. After designing a pair of primer for the gene encoding MBP, PCR analysis was performed. Finally, the PCR prod­uct has been sequenced and the result submitted to the gene data banks. Results: An MBP gene of 1081 nucleotides was sequenced. This fragment contained three introns and encodes a protein with 194 amino acids. Homology search by Blast program showed a significant homology with the MBP gene in gene data banks (96%). Besides, the identity of amino acids with the other MBPs in gene data banks was about 86%. Conclusion: We isolated and sequenced a gene fragment encoding MBP in an Iranian isolate of A.castellanii. Molecular characteri­zation of this important gene is the first step in pursuing researches such as developing better therapeutic agents, im­mu­nization of population at risk or even developing a diagnostic tool by PCR techniques. https://ijph.tums.ac.ir/index.php/ijph/article/view/2050 https://ijph.tums.ac.ir/index.php/ijph/article/download/2050/2031

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 37 2 2008 06 15 15 23 M Saadati A Godarzi M Akbari MB Salehi H Shirzad M Jahani AA Rahimi 2015 10 03 Background: Cholera, an infectious disease caused by Vibrio cholerae, is primarily transmitted by ingestion of contaminated food or water. In severe cases, cholera may lead to severe dehydration, metabolic acidosis, and ultimately, hypovolemic shock and death.   Methods: In this study V.cholerae non-O1 was cultured in suitable media. LPS was extracted from the surface of  bacteria by hot phenol-water method and then purified by high-speed centrifugation. For production of specific antibody against LPS, white newzeland rabbits were first immunized by whole cell bacteria and then immunized with highly purified LPS. The titre of the antiserum was determined by ELISA for each serogroup. Results: Results presented in this study indicate that serum anti-LPS antibodies raised against purified LPS of V.cholerae non-O1 can detect V.cholerae non-O1.   Conclusion: This antibody had low cross reactivity with V.cholerae O1, serotype Inaba or Ogawa. So, this antibody can be used for for detection of V. cholerae non-O1. https://ijph.tums.ac.ir/index.php/ijph/article/view/2051 https://ijph.tums.ac.ir/index.php/ijph/article/download/2051/2032

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 37 2 2008 06 15 24 31 B Shams P Golshiri AR Zamani S Pourabdian 2015 10 03 Background: Assessment of national children growth has shown that a high percent of Country's children are afflicted to growth failure. Community participation is one of the principles of PHC emphasized by WHO that is necessary for develop­ment of health services. The objective of this study was to develop a model for mother's participation in order to improving growth and nutrition of children. Methods: This community-based field trial was rendered on 74 pairs of mothers and children less than three years of age. A model was designed for increasing mother's participation, so that, a group of mother's volunteered and were instructed in the subjects of growth monitoring and child nutrition. The program was evaluated by CIPP Model (Context, Input, Product, Proc­ess). Results: Difference between the mean grade of mothers' knowledge and practice, before and after intervention were mean­ing­ful (P< 0.001).This plan had considerable effects on the increase of individual and social capabilities of the partici­pants, including their self-confidence. Other findings were related to the evaluation of impact, effectiveness, sustainability and transportability of the program. Conclusion: By enhancement of mother's participation, considerable improvement of their knowledge and practice concern­ing growth and nutrition of children were achieved. Also individual and social capabilities of the mothers' in­creased. https://ijph.tums.ac.ir/index.php/ijph/article/view/2052 https://ijph.tums.ac.ir/index.php/ijph/article/download/2052/2033

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 37 2 2008 06 15 32 40 M Hodjat A Talebian MA Akhondi H Zeraati A Shabani MR Sadeghi 2015 10 03 Background: Ubiquitin, an 8.5 kDa peptide that marks other proteins for proteasomal degradation, tags defective sperm dur­ing epididymal passage. Thus, sperm ubiquitination is a universal marker for sperm defects and can be used as a sperm func­tion test. The objective of the present study was to examine the relationships between sperm ubiquiti­nation and clinical se­men parameters, using simplified immunofluorescence assays in order to establish ubiq­uitin as a biomarker of male infertil­ity. Methods: Semen samples from 100 couples attending Avicenna Infertility Clinic, Tehran, Iran, were collected and ana­lyzed ac­cording to WHO criteria. Each sample was washed and adjusted at 106 sperm/ml concentration. Sperm were coated on slides, using cytospin centrifugation and were fixed in buffered formaldehyde. Subsequently ubiq­uiti­nated spermatozoa were evaluated by direct immunofluorescence microscopy using FITC-labeled anti-ubiq­uitin antibodies. After counting at least 200 sperm per sample, while employing light microscopy, the percentage of ubiq­uitinated spermatozoa was recorded on the same fields through epifluorescence microscopy. Results: Negative correlations were obtained between sperm ubiquitination and sperm count (r=-0.278, P< 0.001), sperm concen­tration (r=-0.37, P< 0.001), viability (r=-0.407, P< 0.001), sperm morphology (r=-0.509, P< 0.001), rapid progres­sive motility (a) (r=-0.246, P< 0.001) and slow progressive motility (b) (r=-0.474, P< 0.001). There was a positive correla­tion between ubiquitinated sperm and the percentage of immotile spermatozoa (r=0.486, P< 0.000). Conclusion: Increased sperm ubiquitination is inversely associated with good semen quality parameters, supporting the use of ubiquitin as a biomarker for evaluation of human sperm quality. https://ijph.tums.ac.ir/index.php/ijph/article/view/2053 https://ijph.tums.ac.ir/index.php/ijph/article/download/2053/2034

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 37 2 2008 06 15 41 50 P Dehghan F Zaini M Mahmoudi A Jebali P Kordbacheh S Rezaei 2015 10 03 Backgrounds: To obtain information about clinical isolates of Aspergillus flavus group. Methods: We examined 55 isolates [45 clinical, 10 reference (6 from culture collections, 4 local reference)] for toxicology, growth rates, and morphological and physiological characteristics. Modified Czapek Agar (CZ) and Malt Extract Agar (MEA) were used for observing microscopic morphology and measuring fungal structures. Two additional media, Potato Dex­trose Agar (PDA) and a modified Rice Agar (RA), were used to detect fluorescence under UV light. The presence of afla­toxin in culture extracts was confirmed by thin-layer chromatography (TLC). Results: 66.6% and 55.5% of clinical samples showed different shade of fluorescence on RA and PDA, respectively, after expo­sure to UV light. Fifteen (33.3%) of the clinical isolates and 3 (30%) of the reference strains produced sclerotia on Czapek Yeast Agar (CYA) at 37° C. Sclerotia formation was promoted at 37°C in comparison with 28°C on CYA medium (P< 0.001). Five (11.11%) of the clinical isolates, the Iranian A. flavus soil reference strain and A. parasiticus ATCC15517 were confirmed to be aflatoxiginc by TLC. From two clinical toxigenic isolates (of 5) which were fluorescence positive on PDA, only one produced fluorescence on RA after exposure to UV light. Moreover sclerotia production was observed in only 3 of 5 toxigenic isolates. Furthermore one isolate from a sinus specimen was identified as Aspergillus oryzae. This is be­lieved to be the first report of sinusitis due to A. oryzae from Iran. Conclusion: Some of clinical A. flavus isolates could have aflatoxin and sclerotia producing ability, but not necessarily all aflatoxi­genic A. flavus isolates are capable of producing sclerotia. https://ijph.tums.ac.ir/index.php/ijph/article/view/2054 https://ijph.tums.ac.ir/index.php/ijph/article/download/2054/2035

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 37 2 2008 06 15 51 58 M Heidari Z Ousati- Ashtiani MH Modarressi M Aarabi 2015 10 03 Background: Hox genes are well-known transcription factors that play essential roles in directing embryonic development. TGIFLY is a Y-linked homeobox gene that was originally identified by virtue of its expression in adult testis. The functions of TGIFLY in normal and abnormal development are unknown. Methods: To investigate the potential roles of TGIFLY gene in the infertile males, a semi-nested Reverse Transcriptase Po­ly­merase Chain Reaction (RT-PCR) was performed on the testicular samples of 110 patients with non-obstructive azoosper­mia. Results: The expression of TGIFLY in 59(53.6%) out of 110 patients were undetectable. Patients with different sper­mato­gene­sis defects failed to show the expected in TGIFLY gene expression as demonstrated in the normal testes. Conclusion: Our results indicate that TGIFLY is expressed in testis and could be associated with infertility in patients with azoo­spermia. TGIFLY may be required for the regulation of spermatogonial stem cell specification and proliferation that is es­sen­tial to the establishment and maintenance of spermatogenesis in human. https://ijph.tums.ac.ir/index.php/ijph/article/view/2055 Zhilan CHEN Reproductive Medical Center, Wuhan Central Hospital, Wuhan, China Liyong CHEN Department of Anesthesiology, Research Institute of Surgery and Daping Hospital, Third Military Medical University, Chongqing, China 2020 01 29 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/19595 https://ijph.tums.ac.ir/index.php/ijph/article/download/19595/6679

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 2 2020 02 01 257 266 Xueguang GUO Department of Medical Oncology, Chinese PLA General Hospital, Beijing, China Gang LIU Department of Hepatobiliary & Enteric Surgery, Xiangya Hospital, Central South University, Changsha, China Xiaoping XIE Department of Gastroenterology Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, China Jing LI Department of Oncology, Zhongshan Hospital Affiliated to Guangzhou University of Chinese Medicine, Zhongshan, China Zehui HOU Department of Gastrointestinal and Hernia Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China Yanhong GU Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China Lijiang YU Department of Internal Medicine-Oncology, Jingjiang People’s Hospital, Jingjiang, China 2020 01 29 Background: We aimed to detect IL-17, MMP-9 and CD23 in serum of patients with colorectal cancer to provide some proper references for diagnosis and treatment of this disease. Methods: Overall, 287 patients with colorectal cancer were collected in the Digestive Surgery Department of Chinese PLA General Hospital, Beijing, China from January 2017 to November 2018 and were used as the study group, meanwhile, 200 people who took physical examination in the same period were used as the control group. They were retrospectively analyzed. The concentrations of IL-17, MMP-9 and CD23 in serum were detected by ELISA 10 d before and after treatment and 30 d after treatment. The relationship between IL-17, MMP-9 and CD23 concentration and clinicopathology was analyzed. Results: The concentrations of CD23, IL-17 and MMP-9 in peripheral blood of the patients in the study group were significantly higher than those in the control group (P<0.001). IL-17, MMP-9 and CD23 were negatively correlated with treatment time and pathological features in the study group (P<0.001). Conclusion: The concentrations of IL-17, MMP-9 and CD23 obviously increased in peripheral blood of patients with colorectal cancer, the three were negatively correlated with treatment time and were significantly correlated with TNM staging and differentiation degree of colorectal cancer. It is expected to estimate the illness. https://ijph.tums.ac.ir/index.php/ijph/article/view/19573 https://ijph.tums.ac.ir/index.php/ijph/article/download/19573/6662

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 2 2020 01 29 394 396 Sook-Young RYU Institute of General Education, Seoul Women’s University, Seoul, Korea Wi-Young SO Sports and Health Care Major, Korea National University of Transportation, Chungju-si, Korea 2020 01 29 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/19596 https://ijph.tums.ac.ir/index.php/ijph/article/download/19596/6680

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 2 2020 01 29 267 273 Christian KIM Department of General Education, CHA University, Pocheon, South Korea Song Yi LEE Department of Airline Service, Dong Yang University, Yeongju, South Korea Sam-Hun PARK Asia Contents Institute, Konkuk University, Seoul, South Korea 2020 01 29 Background: This study attempted to identify the problem South Korea faces in its development of the medical tourism industry from the perspective of English education. Methods: To assess the preparedness and problems of future Korean nurses in dealing with foreign patients, a questionnaire was conducted in 2017 on 146 freshman and sophomore nursing major students at CHA University in South Korea. Results: Although the nursing major students were highly satisfied with the English instructors, they did not feel that the curriculum prepared them well to deal with foreign patients in the future. They also felt that the teaching methodology employed in the class should be changed to incorporate more medical content into the nursing English program. Conclusion: In order for South Korea to play a bigger role in the medical tourism industry, higher education institutions for medicine need to pay more attention to the English education of their students. More specifically, team-taught English for Specific Purposes (ESP) curricula should be established in order to meet the needs of future medical professionals. https://ijph.tums.ac.ir/index.php/ijph/article/view/19574 https://ijph.tums.ac.ir/index.php/ijph/article/download/19574/6663

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 2 2020 02 01 397 399 Wenwen WU Department of Occupational and Environmental Health, School of Health Sciences, Wuhan University, Wuhan, China Xiaodong TAN Department of Occupational and Environmental Health, School of Health Sciences, Wuhan University, Wuhan, China Yu XIE Department of Occupational and Environmental Health, School of Health Sciences, Wuhan University, Wuhan, China Qiru WANG Department of Occupational and Environmental Health, School of Health Sciences, Wuhan University, Wuhan, China Yalin ZHANG Department of Occupational and Environmental Health, School of Health Sciences, Wuhan University, Wuhan, China 2020 01 29 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/19597 https://ijph.tums.ac.ir/index.php/ijph/article/download/19597/6681

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 2 2020 02 01 274 282 Milos M. STEPOVIC Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Dalibor STAJIC Department of Hygiene and Ecology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Marija SEKULIC Department of Hygiene and Ecology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Zlata RAJKOVIC Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia Nela DJONOVIC Department of Hygiene and Ecology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia AND Institute of Public Health, Kragujevac, Serbia 2020 01 29 Background: Lip, oral cavity, and pharyngeal cancers have been globally estimated to account for about 3.8% of all cancer cases and 3.6% of cancer deaths. Mortality of these cancers is generally higher in developing than in developed countries. Overall cancer mortality rate in Serbia is one of the highest in the world. The aim of this study was to determine the mortality rate trends and the most common localization of lip, oral and pharyngeal cancers in Serbia. Methods: The study was conducted in 2018 as descriptive epidemiological study and included years from 1999 to 2015. The differences in standardized mortality rates and number of deaths were analyzed with regard to age, gender, and tumor localization. Linear trend and regression were used to determine mortality rate trend. Results: There was statistically significant difference in the number of deaths between men and women in the ages of 40 and over (P < 0.01); male/female cancer mortality ratio was 4.56:1. Generally, the most common localization of this carcinoma was hypopharynx. There was no statistically significant increase of mortality rates from these cancers for both genders (males: y = 4.77 + 0.42x, P = 0.069 % change = +20.35; females: y = 1.03 + 0.01x, P = 0.40 % change = +4) during 17-year period. Conclusion: Promotion of healthy habits, life-styles and regular inspection of mouth by patients and health professionals should be better prioritized especially in developing countries where implementing and improving national health prevention programs are essential. https://ijph.tums.ac.ir/index.php/ijph/article/view/19577 https://ijph.tums.ac.ir/index.php/ijph/article/download/19577/6664

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 2 2020 02 01 400 402 Darko DIMOVSKI Faculty of Law, University of Niš, Niš, Republic of Serbia Veljko TURANJANIN Faculty of Law, University of Kragujevac, Kragujevac, Republic of Serbia Milica KOLAKOVIĆ-BOJOVIĆ Institute of Criminologial and Sociological Research, Belgrade, Republic of Serbia Dragana ČVOROVIĆ Academy of Criminalistic and Police Studies, Belgrade, Republic of Serbia 2020 01 29 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/19598 https://ijph.tums.ac.ir/index.php/ijph/article/download/19598/6682

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 2 2020 02 01 283 293 Xuewei ZHANG School of Economics and Management, Beijing University of Technology, Beijing, China Zong GANG School of Economics and Management, Beijing University of Technology, Beijing, China Xiao DONG School of Finance, Henan University of Economics and Law, Zhengzhou, Henan, China 2020 01 29 Background: The proportion of government healthcare expenditure in China increases due to rapid economic development in recent years. The growth of government healthcare expenditure can promote physical health improvement of human capitals and thereby facilitate economic growth. Hence, exploring the effects of government healthcare expenditure on economic growth is important. Methods: Spatial correlation of economic growth under different spatial weights was tested, and the effects of government healthcare expenditure on economic growth were analyzed by constructing a spatial Durbin model with the panel data of 31 provinces in China gathered from 2005 to 2017. Results: Government healthcare expenditure in China significantly and positively affects economic growth under three spatial weight matrices. The spatial weight of economic distance influences economic growth more significantly compared with the 0–1 spatial weight and the spatial weight of geographical distance. The total and the direct effects of government healthcare expenditure are significantly positive. Furthermore, the direct effects are significant, whereas the indirect effects show different degrees of significance. Conclusion: The total effect of government healthcare expenditure on economic growth is significant and positive, with direct effects exceeding the indirect ones. Hence, the China’s government must continue to increase financial investment to public health services to promote high-quality economic growth in the country. https://ijph.tums.ac.ir/index.php/ijph/article/view/19578 https://ijph.tums.ac.ir/index.php/ijph/article/download/19578/6665

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 2 2020 02 01 403 405 Mahdi Ben DHAOU Department of Pediatric Surgery, Hedi-Chaker Hospital, Sfax, Tunisia AND Sfax Medical School, Sfax, Tunisia Mohamed ZOUARI Department of Pediatric Surgery, Hedi-Chaker Hospital, Sfax, Tunisia AND Sfax Medical School, Sfax, Tunisia Salma AMMAR Department of Pediatric Surgery, Hedi-Chaker Hospital, Sfax, Tunisia AND Sfax Medical School, Sfax, Tunisia Naourez GOUIAA Sfax Medical School, Sfax, Tunisia AND Department of Pathology, Habib Bourguiba Hospital, Sfax, Tunisia Manel HAJ MANSOUR Department of Pediatric Surgery, Hedi-Chaker Hospital, Sfax, Tunisia AND Sfax Medical School, Sfax, Tunisia Mohamed JALLOULI Department of Pediatric Surgery, Hedi-Chaker Hospital, Sfax, Tunisia AND Sfax Medical School, Sfax, Tunisia Thouraya BOUDAWARA Sfax Medical School, Sfax, Tunisia AND Department of Pathology, Habib Bourguiba Hospital, Sfax, Tunisia Riadh MHIRI Department of Pediatric Surgery, Hedi-Chaker Hospital, Sfax, Tunisia AND Sfax Medical School, Sfax, Tunisia 2020 01 29 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/19599 https://ijph.tums.ac.ir/index.php/ijph/article/download/19599/6683

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 2 2020 02 01 294 303 Khaled TAFRAN Department of Administrative Studies and Politics, Faculty of Economics and Administration, University of Malaya, Kuala Lumpur, Malaysia Makmor TUMIN Department of Administrative Studies and Politics, Faculty of Economics and Administration, University of Malaya, Kuala Lumpur, Malaysia Ahmad Farid OSMAN Department of Applied Statistics, Faculty of Economics and Administration, University of Malaya, Kuala Lumpur, Malaysia 2020 01 29 Background: The primary indicator of public health, which all nations aim to prolong, is life expectancy at birth. Uncovering its socioeconomic determinants is key to extending life expectancy. This study examined the determinants of life expectancy in Malaysia. Methods: This observational study employs secondary data from various official sources of 12 states and one federal territory in Malaysia (2002-2014). Panel data of 78 observations (13 cross-sections at six points in time) were used in multivariate, fixed-effect, regressions to estimate the effects of socioeconomic variables on life expectancy at birth for male, female and both-gender. Results: Poverty and income significantly determine female, male, and total life expectancies. Unemployment significantly determines female and total life expectancies, but not male. Income inequality and public spending on health (as a percentage of total health spending) do not significantly determine life expectancy. The coefficients of the multivariate regressions suggest that a 1% reduction in poverty, 1% reduction in unemployment, and around USD 23.20 increase in household monthly income prolong total life expectancy at birth by 17.9, 72.0, and 16.3 d, respectively. The magnitudes of the effects of the socioeconomic variables on life expectancy vary somewhat by gender. Conclusion: Life expectancy in Malaysia is higher than the world average and higher than that in some developing countries in the region. However, it is far lower than the advanced world. Reducing poverty and unemployment and increasing income are three effective channels to enhance longevity. https://ijph.tums.ac.ir/index.php/ijph/article/view/19579 https://ijph.tums.ac.ir/index.php/ijph/article/download/19579/6666

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 2 2020 02 01 406 408 Abdelhafid BENKSIM Laboratory of Human Ecology, Semlalia School, Marrakesh, Morocco AND High Institute of Nursing and Technical Health (ISPITS), Marrakesh, Morocco Rachid AIT-ADDI Laboratory of Human Ecology, Semlalia School, Marrakesh, Morocco Noureddine ELKHOUDRI Institute of Health Sciences, University Hassan-1, Settat, Morocco Mohamed AMINE Faculty of Medicine and Pharmacy, Marrakesh, Morocco Mohamed CHERKAOUI Laboratory of Human Ecology, Semlalia School, Marrakesh, Morocco 2020 01 29 No Abstract https://ijph.tums.ac.ir/index.php/ijph/article/view/19601 https://ijph.tums.ac.ir/index.php/ijph/article/download/19601/6684

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 49 2 2020 01 29 304 311 Peiquan HUI Department of Neurosurgery, People's Hospital of Weifang, Weifang, Shandong, China Yuling WANG Department of Ultrasonography, People's Hospital of Weifang, Weifang, Shandong, China Bing CHEN Department of Neurosurgery, People's Hospital of Weifang, Weifang, Shandong, China Zengwu WANG Department of Neurosurgery, People's Hospital of Weifang, Weifang, Shandong, China Shiqiang QIN Department of Neurosurgery, People's Hospital of Weifang, Weifang, Shandong, China 2020 01 29 Background: To investigate the expression of microRNA-29c (miR-29c) in glioma and its effects on cell proliferation and apoptosis. Methods: A retrospective analysis was performed on 76 glioma patients in People's Hospital of Weifang, Weifang, Shandong, China from May 2013 to June 2017 (experimental group) and 63 healthy subjects in the same period (control group). qRT-PCR was used to detect the miR-29c expression.