Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 10 2016 12 14 1355 1358 Mohammad KHANAHMADI Aging Research Center, Farhud Scientific-Cultural Foundation, Tehran, Iran Dariush D.FARHUD School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Dept. of Basic Sciences/Ethics, Iranian Academy of Medical Sciences, Tehran, Iran Maryam MALMIR Research Center of Life Style, Medical Sciences Branch, Islamic Azad University, Tehran, Iran Soheila ORANG Dept. of Psychology, Kharazmi University, Tehran, Iran 2016 10 23 2016 10 23 Background: Metal ions effect on homeostasis of Alzheimer’s disease (AD) patients. The aim of this study was to assess the metal ions (Iron, Zinc and Copper) and CBC in patients with AD in comparison with normal range. Methods: The samples of study were 17 patients with AD in Tehran’s aging centers in 2015, selected as an access sample. Blood samples were analyzed in a pathobiology laboratory. Data were analyzed by one sample t-test. Results: According to the normal range, provided by laboratory, there is a significant difference between zinc in patients with AD and normal reference interval (α=0.01). The comparison of CBC of the AD patients with normal group showed also some decreases Conclusion: Zinc value in AD patients is significantly lower than normal range. It should be repeated by a larger sample size.   https://ijph.tums.ac.ir/index.php/ijph/article/view/8075 https://ijph.tums.ac.ir/index.php/ijph/article/download/8075/5583