Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 45 3 2016 03 15 376 380 Mohammad Yahya VAHIDI MEHRJARDI Medical Genetics Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AND Dept. of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Masoud DEHGHAN TEZERJANI Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mahmoud NORI-SHADKAM Dept. of Pediatrics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Seyed Mehdi KALANTAR Dept. of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AND Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mohammadreza DEHGHANI Medical Genetics Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran AND Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 2016 03 15 2016 03 15 The interpretation of supernumerary chromosome is important for genetic counseling and prognosis. Here, we used SNP array and conventional karyotyping method to identify a denovo marker chromosome originated from chromosome 22 and 11 in a newborn transferred to the Neonatal Intensive Care Unit of Shahid Sadoughi Hospital in 2015.  Clinical abnormalities identified in the newborn were dysmorphic face, intrauterine growth retardation, atrial septal defect (ASD), the hypoplasia of corpus callosum and septum pellucidum. These clinical abnormalities can be related to this marker, and it may help genetic counselor for predicting abnormality risk in susceptible individuals as well as prenatal diagnosis.    https://ijph.tums.ac.ir/index.php/ijph/article/view/6271 https://ijph.tums.ac.ir/index.php/ijph/article/download/6271/5334