Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 42 1 2013 01 15 1 6 Dariush D Farhud School of Public Health, Tehran University of Medical Sciences, Tehran, Iran ; Tehran Genetic Clinic, 22 Keshavarz Blv, Tehran, Iran. Marjan Zarif Yeganeh 2015 10 15 The evolution of human blood groups, without doubt, has a history as old as man himself. There are at least three hypotheses about the emergence and mutation of human blood groups. Global distribution pattern of blood groups depends on various environmental factors, such as disease, climate, altitude, humidity etc. In this survey, the collection of main blood groups ABO and Rh, along with some minor groups, are presented. Several investigations of blood groups from Iran, particularly a large sampling on 291857 individuals from Iran, including the main blood groups ABO and Rh, as well as minor blood groups such as Duffy, Lutheran, Kell, KP, Kidd, and Xg, have been reviewed. https://ijph.tums.ac.ir/index.php/ijph/article/view/4769 https://ijph.tums.ac.ir/index.php/ijph/article/download/4769/4407