Myelodysplastic Syndrome with 6q Deletion as the Sole Chromosome Abnormality in an Iranian Patient: A Case Report with Review of Literature

Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 42 10 2013 10 15 Myelodysplastic Syndrome with 6q Deletion as the Sole Chromosome Abnormality in an Iranian Patient: A Case Report with Review of Literature 1187 1191 Shirin Ferdowsi 1. Dept. of Hematology, Iranian Blood Transfusion Organization , Tehran, Iran. Reza Shirkoohi 2. Dept. of Molecular Genetics, Cancer Research Center, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences , Tehran, Iran. Gholamreza Toogeh 3. Dept. of Hematology-Oncology and BMT Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences , Tehran, Iran. 2015 10 15 The myelodysplastic syndrome (MDS) is a highly heterogenous disorder and karyotype analysis is helpful for diagnostic and prognostic estimation. Deletion in long arm chromosome 6 (6q del) as a sole abnormality is a rare event in MDS. This is the first case report of del (6q) as the only observed diagnostic change in Iran. We also reviewed the literature of this cytogenetic lesion. https://ijph.tums.ac.ir/index.php/ijph/article/view/4376 https://ijph.tums.ac.ir/index.php/ijph/article/download/4376/4025