Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 43 9 2014 09 15 1295 8 Asadollah Mirzaie 1. Dept. of Cardiac Surgery, Mashhad University of Medical Sciences , Mashhad, Iran. Majid Reza Erfanian-Taghvaei 2. Dept. of Community Medicine, Mashhad University of Medical Sciences , Mashhad, Iran. Maryam Mirzaie 3. Dept. of Community Medicine, Mashhad University of Medical Sciences , Mashhad, Iran. Reza Sharifi-Noghabi 4. Dept. of General Surgery, Gonabad University of Medical Sciences , Gonabad, Iran. 2015 10 15 Hydatid cyst disease should be considered in differential diagnosis in many doubtful clinical situations as can present with non-specific symptoms especially in the endemic areas. Cardiac involvement should be considered in patients with history of previous hydatid cyst disease.. Cardiac hydatid cysts account for less than 2% of all hydatid diseases. In this report we aimed to present a case of 14-year-old boy with the diagnosis of occlusion of artery of the right lower extremity. Surgical exploration of the femoral artery revealed multiple hydatid cysts. Echocardiography showed a mobile mixed mass lesion. Complete resection of the mass was done from interventricular septum. Histo-pathological examination of the removed tissue revealed a complicated hydatid cyst and complete mass excision was confirmed. In this case a 7 year clinical and serological tests evaluation follow-up after surgical treatment showed no evidence of recurrence. The finding of this case emphasizes that in endemic countries, primary cardiovascular echino-coccosis should be considered in differential diagnosis. https://ijph.tums.ac.ir/index.php/ijph/article/view/3916 https://ijph.tums.ac.ir/index.php/ijph/article/download/3916/3577