Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 54 11 2025 11 28 2395 2407 Azim Karimi Department of Occupational Health and Safety Engineering, Faculty of Health, Isfahan University of Medical Sciences, Isfahan, Iran Esmaeil Zarei Embry-Riddle Aeronautical university, prescott,AZ, 86301. USA Ehsanollah Habibi 1. Department of Safety Science, College of Aviation, Embry-Riddle Aeronautical University, Prescott, AZ, 86301, USA 2. Robertson Safety Institute (RSI), Embry-Riddle Aeronautical University, Prescott, AZ, 86301, USA Fatemeh Aminaei Department of Occupational Health and Safety Engineering, Isfahan Health Center, Isfahan University of Medical Sciences, Isfahan, Iran 2025 01 24 2025 09 02 Background: This systematic review aimed to clarify the individual factors that contribute to unsafe behaviors in industrial workplaces. Methods: An initial search across PubMed, Web of Science, Google Scholar, and Scopus yielded 2,348 articles published between 2000 and 2023. After a rigorous screening process using the PRISMA guideline, 51 studies meeting the inclusion criteria—focusing on individual determinants of unsafe behaviors in industrial environments were selected for in-depth analysis. Results: The systematic analysis revealed a multifaceted relationship between individual factors and the occurrence of unsafe behaviors. Key themes include the influence of demographic attributes, psychological needs and desires, cognitive factors, and health conditions. The dual-focused approach of addressing both organizational and individual dimensions emerged as crucial for effective safety management. The synthesis of evidence underscores the significance of individual factors in shaping workplace safety. While organizational strategies remain integral, our findings emphasize the complementary role of individual-focused initiatives. A notable gap in the absence of a comprehensive tool for examining all individual factors points toward a crucial avenue for future research. Conclusion: This review contributes essential insights for organizational leaders, safety managers, and policymakers seeking to enhance safety protocols and create safe and resilient work environments. https://ijph.tums.ac.ir/index.php/ijph/article/view/37955 https://ijph.tums.ac.ir/index.php/ijph/article/download/37955/8698