Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 54 11 2025 11 28 The Relation of Air Pollution on Morbidity and Mortality of SARS CoV 2 Infection in Tekirdag, Türkiye 2463 2472 Gamze Varol Department of Public Health, Tekirdağ Namık Kemal University School of Medicine, Tekirdağ, Türkiye Burcu Tokuç Department of Public Health, Tekirdağ Namık Kemal University School of Medicine, Tekirdağ, Türkiye Ülfiye Çelikkalp Department of Public Health, Trakya University School of Medicine, Edirne, Türkiye Nilay Etiler Public Health Practice Department, School of Public Health, University of Okan, İstanbul, Türkiye 2024 11 27 2025 08 10 Background: We aimed to investigate the relation between environmental air pollutants such as Particulate Matter 10 (PM10), Particulate Matter 2.5 (PM2.5), Sulfur Dioxide (SO2) on daily cases and deaths associated with SARS-CoV-2 infection. Methods: The ecological research examined the correlations of the air quality metrics and the data of COVID-19 cases and deaths from March 1, 2020 to March 1, 2021 in the central District of Tekirdağ Province in Türkiye. Results: During the study period, the average PM10 concentration was 32.57±17.86 µg/m3, PM2.5 was 20.68±11.31 µg/m3, SO2 was 11.28±13.42 µg/m3, and NO2 was 19.07±7.26 µg/m3. The SARS-CoV-2 case fatality rate in the study area during this period was 3.2%. Correlation analyses between air pollutants and SARS-CoV-2 cases and deaths revealed significant positive associations between SARS-CoV-2 cases (r=0.220 for PM10, P<0.001; r=0.290 for PM2.5, P<0.001; r=0.218 for SO2, P<0.001) and deaths (r=0.203 for PM10, P<0.001; r=0.289 for PM2.5, P<0.001; r=0.278 for SO2, P<0.001). Moreover, regression analysis revealed that ambient sulfur dioxide (SO₂) levels significantly predicted both COVID-19 incidence and mortality. Conclusion: PM10, PM2.5, and SO2, key parameters for assessing air quality, exhibit a positive relationship with the increasing number of daily SARS-CoV-2 cases and daily deaths in the study area.  https://ijph.tums.ac.ir/index.php/ijph/article/view/37337 https://ijph.tums.ac.ir/index.php/ijph/article/download/37337/8703