Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 54 6 2025 06 02 1118 1131 Liang Zhang School of Foreign Studies, China University of Political Science and Law, Changping District, Beijing, 102249, China 2024 11 23 2025 01 21 Background: A meta-analysis study was conducted to measure how to forecast the effect of treatment of hypokinetic dysarthria in Parkinson's-disease with speech and language therapy. Methods: Until October 2024, a comprehensive literature research was conducted, and 1665 related studies were reviewed.  The 14 selected studies encompassed 948 participants with hypokinetic dysarthria in Parkinson's disease.  The odds ratio (OR) mean difference (MD) and 95% confidence intervals (CIs) were used to look at the outcome of treatment of hypokinetic dysarthria in Parkinson's disease with speech and language therapy using dichotomous or continuous methods with a fixed- or random-effects model. Results: In individuals with hypokinetic dysarthria in Parkinson-disease, speech and language therapy had significantly higher sound pressure level, phonation (MD, 7. 51; 95% CI, 3. 81-11. 20, p<0. 001), reading (MD, 8. 83; 95% CI, 4. 96-12. 69, p<0. 001), monologue (MD, 4. 28; 95% CI, 2. 47-6. 10, p<0. 001), and picture description (MD, 3. 64; 95% CI, 1. 78-5. 50, p<0. 001), and lower Voice Handicap Index (MD, -5. 61; 95% CI, -9. 05- -2. 17, p=0. 001) compared to control treatment. Conclusion: In individuals with hypokinetic dysarthria in Parkinson's disease, speech and language therapy had significantly higher sound pressure level, phonation, reading, monologue, and picture description, and lower Voice Handicap Index compared to control treatment. To validate these finding more studies are required, caution is needed when interpreting these results, since many comparisons had a limited number of selected studies. https://ijph.tums.ac.ir/index.php/ijph/article/view/37283 https://ijph.tums.ac.ir/index.php/ijph/article/download/37283/8564