Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 53 11 2024 11 04 2509 2518 Se Hwa Park Jeonnam Technology and Science High School, Jeonnam, Korea Jin Hee Lee Department of Nursing, Kwangju Women’s University, Gwangju, Korea 2024 10 09 2024 11 04 Background: We aimed to identify the factors influencing safety accident management activities for hospitalized children in children’s hospitals. Methods: In August 2022, data were collected from 170 nurses across seven children’s hospitals in Gwangju Metropolitan City, Korea. The collected data were analyzed using independent t-tests, analysis of variance, Pearson’s correlation analysis, and multiple regression analysis. Results: Safety accident management activities for hospitalized children differ significantly based on nurses’ experience in children’s hospitals (P=0.048). Safety accident management activities were positively correlated with patient safety culture (r=0.47, P<0.001), critical thinking (r=0.35, P<0.001), and nursing work environment (r=0.51, P<0.001). Furthermore, the most influential determinant of safety accident management activities for hospitalized children was the nursing work environment (β=0.42, P<0.001), followed by nurses’ experience in children’s hospitals (β=0.20, P=0.004), and patient safety culture (β=0.17, P=0.041). These variables had an explanatory power of 34.0 % (adjusted R2=0.34, P<0.001). Conclusion: A positive nursing work environment and strong patient safety culture are essential for increasing safety accident management activities among children’s hospital nurses. Additionally, children’s hospitals should provide support to the nursing staff and implement policies that encourage long-term retention of experienced nurses. https://ijph.tums.ac.ir/index.php/ijph/article/view/36865 https://ijph.tums.ac.ir/index.php/ijph/article/download/36865/8394