Tehran University of Medical Sciences Iranian Journal of Public Health 2251-6085 44 4 2015 04 15 535 42 Masoumeh Mohajer Rahbari Dept. of Reproductive Health, Student Research Committee, Shahroud University of Medical Sciences, Shahroud, Iran. Mohammad Shariati Dept. of Community Medicine, Tehran University of Medical Sciences, Tehran, Iran. Afsaneh Keramat Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran. Masoud Yunesian Institute for Environmental Research, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Eslami Dept. of Population, Family and School Health, Ministry of Health and Medical Education, Tehran, Iran. Seyed Abbas Mousavi Golestan Research Center of Psychiatry, Golestan University of Medical Sciences, Gorgan, Iran. Ali Montazeri Mental Health Research Group, Health Metrics Research Center, Iranian Institute for Health Sciences Research, ACECR, Tehran, Iran. 2015 10 14 Background: Although the validity of content of program is mostly conducted with qualitative methods, this study used both qualitative and quantitative methods for the validation of content of post marriage training program provided for newly married couples. Content validity is a preliminary step of obtaining authorization required to install the program in country's health care system. Methods: This mixed methodological content validation study carried out in four steps with forming three expert panels. Altogether 24 expert panelists were involved in 3 qualitative and quantitative panels; 6 in the first item development one; 12 in the reduction kind, 4 of them were common with the first panel, and 10 executive experts in the last one organized to evaluate psychometric properties of CVR and CVI and Face validity of 57 educational objectives. Results: The raw data of post marriage program had been written by professional experts of Ministry of Health, using qualitative expert panel, the content was more developed by generating 3 topics and refining one topic and its respective content. In the second panel, totally six other objectives were deleted, three for being out of agreement cut of point and three on experts' consensus. The validity of all items was above 0.8 and their content validity indices (0.8-1) were completely appropriate in quantitative assessment. Conclusion: This study provided a good evidence for validation and accreditation of national post marriage program planned for newly married couples in health centers of the country in the near future. https://ijph.tums.ac.ir/index.php/ijph/article/view/3590 https://ijph.tums.ac.ir/index.php/ijph/article/download/3590/3265